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                                              Health Safety of Plastics Used for Food and
                                               Drinking Water Packaging: Bisphenol A

Important Facts on Bisphenol A                               Bisphenol A: Description and Uses
Anecdotal stories about contaminants leaching from           BPA is a synthetic chemical compound that is
polycarbonate bottles and epoxy resins used in food          produced at an estimated 2.3 billion pounds a year in
                                                             the U.S.4 Commercially used since the 1950s, BPA is a
packaging materials periodically surface, in particular,
suggesting that real-life conditions of use may release      chemical ingredient commonly used in the production
harmful levels of bisphenol A (also referred to as BPA)      of polycarbonate plastic and epoxy resin, both of which
into contained food and liquids. Due the widespread          are used for a variety of applications. Polycarbonate
use of BPA as an ingredient in a variety of consumer         plastic is a hard and high-performance type plastic
products - for example, baby bottles - the Canadian          labeled using the resin code or container material
Government established a deadline of June 2008 to            symbol        with the number 7 inside and the letters
determine whether or not materials containing BPA            “PC” beneath it. Epoxy resin is commonly used as a
should be banned from use in all food-related                sealant or protective coating. 7 Examples of
consumer products. 1 Wal-Mart, the largest consumer          commonly encountered uses of BPA are to produce
product marketing company in the world, has followed         hard plastic baby bottles, reusable beverage containers
suit and announced it will discontinue the sale of baby      (e.g., water bottles), food storage containers and
bottles containing BPA in the U.S. by 2009. 2,3 Toys-R-      dinnerware, and protective coatings used in metal food
Us will also phase out the sale of baby bottles and          and beverage cans, wine vats, and dental sealants.
other baby-feeding products containing BPA. 3
                                                             Health Effects
Recently, the National Toxicology Program (NTP)
released a draft report affirming “some concern” for
                                                             The primary route of exposure to BPA is through
potential adverse brain and behavior-related
                                                             dietary intake of food and beverages packaged in BPA-
developmental effects associated with exposures to
                                                             containing materials.4 A considerable amount of
BPA. 4 However, NTP does acknowledge that the
                                                             research has been conducted by both governmental and
concerns stem from limited evidence based on
                                                             non-governmental institutions to measure levels of
laboratory animals, which demonstrates the need for
                                                             human exposure to BPA.4 BPA has been detected in
additional research, especially on the long-term health
                                                             urine, blood, breast milk, and tissues in several
effects of current exposure levels. Growing attention
                                                             studies/evaluations from people in the U.S., Europe,
on BPA in the U.S. has sparked Congressional interest
                                                             and Asia. The highest daily intakes of BPA in the
for further investigation 5 and the establishment of a
                                                             general population occur in infants and children
U.S. Food and Drug Administration (FDA) task force
                                                             because they eat, drink, and breathe more than adults
to review concerns and new research on BPA. The
                                                             on a pound for pound basis. Evidence based on animal
FDA Task Force is coordinating closely with the
                                                             testing suggests that adverse developmental effects
Canadian Ministries of Health and the Environment
                                                             related to BPA exposures occur. Some of the observed
and is reviewing the concerns presented in the NTP
                                                             effects include neural and behavioral abnormalities in
draft report and the concerns presented in a Canadian
                                                             rodents. However, these effects occur at levels several
draft risk assessment, both released in April 2008. 6
                                                             thousand times higher than any child or adult would be
                                                             expected to consume on a daily basis.4 More research
                                                             is needed to determine what risks are actually
                                                             associated with BPA, including those resulting from
                                                             long-term, low-level exposures.



                            U.S. Army Center for Health Promotion and Preventive Medicine
                                      Aberdeen Proving Ground, MD 21010-5403
                                     Commercial 410-436-3919 or DSN 584-3919
                                         Email: Water.Supply@amedd.army.mil
                                    http://chppm-www.apgea.army.mil/dehe/pgm31/
sending an email to: Water.Supply@amedd.army.mil.
Current Federal Regulations
                                                            Consumers can also obtain up-to-date news on product
Food, bottled water, and associated packaging sold in       recalls, health advisories, and research on BPA from
and imported into the U.S. are regulated under the          the following websites:
Federal Food, Drug, and Cosmetic Act, and enforced
by the U.S. Food and Drug Administration (FDA).8            U.S. Food and Drug Administration (FDA)
                                                            http://www.fda.gov
The FDA evaluates the potential for certain chemical
constituents of food/beverage packaging (also referred
                                                            www.Recalls.gov (a Federal interagency website for
to as “food contact substances”) to migrate into the
                                                            product recalls) http://www.recalls.gov
contained food or liquid. All substances used to make
packaging materials for food and beverages, including       National Toxicology Program (NTP)
plastics for bottled water, must be determined by the       http://ntp-server.niehs.nih.gov/
FDA to be safe for their intended use before they can
be marketed. 8 As part of the approval process, the         Health Canada
FDA conducts risk assessments to determine the              http://www.hc-sc.gc.ca/index_e.html
amount (if any) and toxicity of material transfer to
ensure that it does not pose a risk to human health,
                                                            References
including the health of infants and children.
                                                            1
                                                              Health Canada News Release, 18 April 2008,
Impact on Department of Defense
                                                            http://www.hc-sc.gc.ca/ahc-asc/media/nr-cp/2008
                                                            /2008_59_e.html (accessed 29 April 2008).
The U.S. Army Veterinary Command is responsible for
all matters of public health/consumer protection related    2
                                                             Ylan Q. Mui, “Wal-Mart to Pull Baby Bottles Made With
to food safety and quality, including bottled water,        Chemical BPA”, The Washington Post, 18 April 2008,
within the Department of Defense. 9 They maintain           http://www.washingtonpost.com (accessed 29 April 2008).
close relations with the FDA, the United States
                                                            3
                                                             Liz Szabo, “More U.S. Retailers Give BPA the Boot”, 21
Department of Agriculture (USDA), and other Federal,
                                                            April 2008, http://www.usatoday.com/news /health/2008-04-
state, and military agencies to ensure consumer
                                                            21-BPA-phase-out_N.htm (accessed 29 April 2008).
protection, food quality, and product safety. They
coordinate daily with Army, Navy, and Air Force             4
                                                             U.S. Department of Health and Human Services (HHS),
public health and preventive medicine organizations on
                                                            National Toxicology Program, “Draft NTP Brief on
inspections of commercial food manufacturing                Bisphenol A”, 14 April 2008.
facilities as well as inspections of military retail food
                                                            5
operations. The U.S. Army ensures that up-to-date            L. Schierow and S.A. Lister, “Bisphenol A (BPA) in
health advisories and related regulations established by    Plastics and Possible Human Health Effects”, Congressional
                                                            Research Service (CRS) Report for Congress, 5 May 2008.
Federal, state, or local agencies are followed.
                                                            6
                                                             U.S. Food and Drug Administration (FDA) News Release
Alternatives and Additional Sources of
                                                            on BPA, http://www.fda.gov (accessed 29 April 2008).
Information
                                                            7
                                                             Society of the Plastics Industry (SPI), “SPI Resin
The FDA reportedly believes that transfers of BPA
                                                            Identification Code: Guide to Correct Use”,
from food contact products to food/beverages are
                                                            http://www.plasticsindustry.org (accessed 6 May 2008).
within reasonable limits of health and safety for
consumers, and recommends that consumers continue           8
                                                             Federal Food, Drug, and Cosmetic Act, codified in the United
to consume food packaged or stored in plastics              States Code, Title 21, Chapter 9 [Food Additives and Food Contact
containing BPA.6 However, consumers may choose              Substances regulations are described in 21 Code of Federal
                                                            Regulations Parts 170-189].
alternatives to products packaged in materials that
contain BPA. Examples of alternatives include glass-        9
                                                             Department of Defense (DOD) Directive 6400.4 “DoD
made baby bottles, stainless steel beverage containers,
                                                            Veterinary Services Program” 22 August 2003 (certified
and fresh foods or foods packaged in glass jars.            current 24 November 2003).
Additional information can be obtained from the U.S.
Army Center for Health Promotion and Preventive
Medicine (USACHPPM) Water Supply Management
Program, by calling commercial (410) 436-3919 or by

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Health Safety Of Plastics Used For Food And Drinking Water Packaging Bisphenol A

  • 1. 31-011-0708 Health Safety of Plastics Used for Food and Drinking Water Packaging: Bisphenol A Important Facts on Bisphenol A Bisphenol A: Description and Uses Anecdotal stories about contaminants leaching from BPA is a synthetic chemical compound that is polycarbonate bottles and epoxy resins used in food produced at an estimated 2.3 billion pounds a year in the U.S.4 Commercially used since the 1950s, BPA is a packaging materials periodically surface, in particular, suggesting that real-life conditions of use may release chemical ingredient commonly used in the production harmful levels of bisphenol A (also referred to as BPA) of polycarbonate plastic and epoxy resin, both of which into contained food and liquids. Due the widespread are used for a variety of applications. Polycarbonate use of BPA as an ingredient in a variety of consumer plastic is a hard and high-performance type plastic products - for example, baby bottles - the Canadian labeled using the resin code or container material Government established a deadline of June 2008 to symbol with the number 7 inside and the letters determine whether or not materials containing BPA “PC” beneath it. Epoxy resin is commonly used as a should be banned from use in all food-related sealant or protective coating. 7 Examples of consumer products. 1 Wal-Mart, the largest consumer commonly encountered uses of BPA are to produce product marketing company in the world, has followed hard plastic baby bottles, reusable beverage containers suit and announced it will discontinue the sale of baby (e.g., water bottles), food storage containers and bottles containing BPA in the U.S. by 2009. 2,3 Toys-R- dinnerware, and protective coatings used in metal food Us will also phase out the sale of baby bottles and and beverage cans, wine vats, and dental sealants. other baby-feeding products containing BPA. 3 Health Effects Recently, the National Toxicology Program (NTP) released a draft report affirming “some concern” for The primary route of exposure to BPA is through potential adverse brain and behavior-related dietary intake of food and beverages packaged in BPA- developmental effects associated with exposures to containing materials.4 A considerable amount of BPA. 4 However, NTP does acknowledge that the research has been conducted by both governmental and concerns stem from limited evidence based on non-governmental institutions to measure levels of laboratory animals, which demonstrates the need for human exposure to BPA.4 BPA has been detected in additional research, especially on the long-term health urine, blood, breast milk, and tissues in several effects of current exposure levels. Growing attention studies/evaluations from people in the U.S., Europe, on BPA in the U.S. has sparked Congressional interest and Asia. The highest daily intakes of BPA in the for further investigation 5 and the establishment of a general population occur in infants and children U.S. Food and Drug Administration (FDA) task force because they eat, drink, and breathe more than adults to review concerns and new research on BPA. The on a pound for pound basis. Evidence based on animal FDA Task Force is coordinating closely with the testing suggests that adverse developmental effects Canadian Ministries of Health and the Environment related to BPA exposures occur. Some of the observed and is reviewing the concerns presented in the NTP effects include neural and behavioral abnormalities in draft report and the concerns presented in a Canadian rodents. However, these effects occur at levels several draft risk assessment, both released in April 2008. 6 thousand times higher than any child or adult would be expected to consume on a daily basis.4 More research is needed to determine what risks are actually associated with BPA, including those resulting from long-term, low-level exposures. U.S. Army Center for Health Promotion and Preventive Medicine Aberdeen Proving Ground, MD 21010-5403 Commercial 410-436-3919 or DSN 584-3919 Email: Water.Supply@amedd.army.mil http://chppm-www.apgea.army.mil/dehe/pgm31/
  • 2. sending an email to: Water.Supply@amedd.army.mil. Current Federal Regulations Consumers can also obtain up-to-date news on product Food, bottled water, and associated packaging sold in recalls, health advisories, and research on BPA from and imported into the U.S. are regulated under the the following websites: Federal Food, Drug, and Cosmetic Act, and enforced by the U.S. Food and Drug Administration (FDA).8 U.S. Food and Drug Administration (FDA) http://www.fda.gov The FDA evaluates the potential for certain chemical constituents of food/beverage packaging (also referred www.Recalls.gov (a Federal interagency website for to as “food contact substances”) to migrate into the product recalls) http://www.recalls.gov contained food or liquid. All substances used to make packaging materials for food and beverages, including National Toxicology Program (NTP) plastics for bottled water, must be determined by the http://ntp-server.niehs.nih.gov/ FDA to be safe for their intended use before they can be marketed. 8 As part of the approval process, the Health Canada FDA conducts risk assessments to determine the http://www.hc-sc.gc.ca/index_e.html amount (if any) and toxicity of material transfer to ensure that it does not pose a risk to human health, References including the health of infants and children. 1 Health Canada News Release, 18 April 2008, Impact on Department of Defense http://www.hc-sc.gc.ca/ahc-asc/media/nr-cp/2008 /2008_59_e.html (accessed 29 April 2008). The U.S. Army Veterinary Command is responsible for all matters of public health/consumer protection related 2 Ylan Q. Mui, “Wal-Mart to Pull Baby Bottles Made With to food safety and quality, including bottled water, Chemical BPA”, The Washington Post, 18 April 2008, within the Department of Defense. 9 They maintain http://www.washingtonpost.com (accessed 29 April 2008). close relations with the FDA, the United States 3 Liz Szabo, “More U.S. Retailers Give BPA the Boot”, 21 Department of Agriculture (USDA), and other Federal, April 2008, http://www.usatoday.com/news /health/2008-04- state, and military agencies to ensure consumer 21-BPA-phase-out_N.htm (accessed 29 April 2008). protection, food quality, and product safety. They coordinate daily with Army, Navy, and Air Force 4 U.S. Department of Health and Human Services (HHS), public health and preventive medicine organizations on National Toxicology Program, “Draft NTP Brief on inspections of commercial food manufacturing Bisphenol A”, 14 April 2008. facilities as well as inspections of military retail food 5 operations. The U.S. Army ensures that up-to-date L. Schierow and S.A. Lister, “Bisphenol A (BPA) in health advisories and related regulations established by Plastics and Possible Human Health Effects”, Congressional Research Service (CRS) Report for Congress, 5 May 2008. Federal, state, or local agencies are followed. 6 U.S. Food and Drug Administration (FDA) News Release Alternatives and Additional Sources of on BPA, http://www.fda.gov (accessed 29 April 2008). Information 7 Society of the Plastics Industry (SPI), “SPI Resin The FDA reportedly believes that transfers of BPA Identification Code: Guide to Correct Use”, from food contact products to food/beverages are http://www.plasticsindustry.org (accessed 6 May 2008). within reasonable limits of health and safety for consumers, and recommends that consumers continue 8 Federal Food, Drug, and Cosmetic Act, codified in the United to consume food packaged or stored in plastics States Code, Title 21, Chapter 9 [Food Additives and Food Contact containing BPA.6 However, consumers may choose Substances regulations are described in 21 Code of Federal Regulations Parts 170-189]. alternatives to products packaged in materials that contain BPA. Examples of alternatives include glass- 9 Department of Defense (DOD) Directive 6400.4 “DoD made baby bottles, stainless steel beverage containers, Veterinary Services Program” 22 August 2003 (certified and fresh foods or foods packaged in glass jars. current 24 November 2003). Additional information can be obtained from the U.S. Army Center for Health Promotion and Preventive Medicine (USACHPPM) Water Supply Management Program, by calling commercial (410) 436-3919 or by