Technical Writer class assignment. A proposal to use needle free injection methods to replace hypodermic needles.

1. Needle Free Injection Technology
Advantages of Needle Free
Injection Systems

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Needle Free Injection Technology
Audience
Medical & Health Boards
Humanitarian Foundations
and Organizations
I represent manufacturers
and developers of needle
free injection technology.

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Needle Free Injection Technology
Companies

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Needle Free Injections
Introduction
I’m here to speak to you about needles,
boosters, vaccinations, flu shots
 We’ve all had to get them
 Most of us don’t like them
 Some people cry, get scared or even faint
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Introduction
Goal of this presentation:
Present alternative methods of medication
delivery.
Discuss the features and advantages of
needle free injection systems over
traditional hypodermic needles in the
administration of serums, vaccinations and
other medicines.
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Introduction
The Problem
 Vaccinations & inoculations
The Current Method
 Hypodermic needles
The Ideal Solution
 Efficient, cost effective
The Proposed Method
 Needle free injectors
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Contents
1. Current Method
 Hypodermic Needles
 Development
 Description
 Advantages
 Problems
2. Ideal Solution
3. Proposed Solution
 Alternative Delivery
Systems
 Needle Free Injectors
 Development
 Description
 Advantages
 Problems
4. Conclusion
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
1. Current
The Current Method
Liquid serums
Needle and syringe
Sterile equipment
Well trained staff
Cultural challenges to
needles
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Development
Hypodermic Needle - a brief history
1844 Irish physician Francis Rynd invented the
hollow needle.
1853 French physician Charles Pravaz &
Edinburgh physician Alexander Wood
independently developed the first practical metal
syringe adding a hollow needle to the end of a
glass syringe.
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Development
An Early Hypodermic Needle
Glass tube
& plunger
Hollow steel
needle
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Description
The Modern Hypodermic Needle
Plastic Syringe &
Plunger
Stainless Steel
Needle in Plastic Tip
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Advantages
Hypodermic Needles are
Inexpensive – needle & syringe
Versatile – wide variety of medicines
Familiar – well known technology
Scaleable – various syringe sizes accommodate different
doses
Introduction Current Ideal Proposed Conclusion
($22.95 for 100 1cc size)
($41.75 for 100 5cc size)
($42.75 for 100 10cc
size)

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Needle Free Injections
Problems
Hypodermic Needle problems
Needlephobia
Substantial training required
Difficult to insert needle to correct depth
Necessary to aspirate the needle to ensure not
hitting a blood vessel
Keeping the needle steady
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Problems
Hypodermic Needle problems
Danger of being stuck by used needle
Disposal of needle tips called “sharps”
Medication waste & ineffective treatment if
delivered to improper depth
Possible re-use of needles
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
2. Ideal Solution
Ideal Solution
Inexpensive
Low-level of Training
Powdered medication (refrigeration, transport)
Non invasive (nothing penetrates the skin except the
medicine)
Dispel Needlephobia
Disposable (no reuse or accidental stick injuries)
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
3. Proposed Solution
The Proposed Method
Needle Free Injection Technology
Safe, clean, efficient
Easy to use, reliable
Various types of medicines
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Alternates
Alternative medication delivery systems
include:
 nasal sprays and drops
 skin patches such as nitroglycerin patches for heart
patients
 inhalers for asthma which deliver pre-measured doses into
the lungs for rapid absorption into the bloodstream
 edible vaccine-packed vegetables (in 1998 potatoes
developed with genes from the cholera virus to protect
against cholera)
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Development
Needle Free Injector Systems
1940s & 1950s air powered injector systems
Gun shaped used propellant gases to force drugs
into the skin
Multiple inoculations in the
military and developing nations
Reusable – risk of infection
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Development
Needle free injectors improved
By the 1990s
 single dose from serum reservoir
 disposable nozzle
 use existing medications
 inject liquid or powder
 self contained propulsion
The Cool Click
from Bioject
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Description
How Needle Free Injectors Work
force medication at high speed through a tiny
hole that is held against the skin
ultra-fine stream of high-pressure fluid or powder
penetrates the skin to various depths
intradermal, subcutaneous, & intramuscular
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Description
Injection modes
Intradermal – very shallow between layers of skin
Subcutaneous – adipose or into the fat layer of the skin
Intramuscular – deepest type, into muscle tissue
Intradermal Subcutaneous Intramuscular
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Description
Injector design: 3 components
Injection device – hand held durable plastic
Disposable needle free syringe – only part that touches
the skin, sterilized and disposable after injection
Air cartridge – pressurized metal air cartridge in portable
units
- larger air container hook ups for in-office systems
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Description
Injector design:
Crossject uses the impact of a spring triggered by the nozzle
touching the skin to activate energetic materials which
produce gas to inject the serum.
Other systems use a re-usable spring to generate the pushing
force instead of air.
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Description
The Crossject Bioject 2000 System
System
Disposable syringe
CO2 Cartridge
Bioject 2000 Injector
Bioject Gas Tank Attachment
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Advantages
Needle Free Injectors
Advantages:
 less drug required to inject the same volume
approximately 8% savings in vaccine
 improved diffusion and more reliable depth of penetration
 reliable penetration means more efficient use of drugs
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Advantages
Needle Free Injectors
Advantages:
 improved safety and protecting against infection
 higher self-treatment rates
 operate with existing formulations which reduces
development and clinical trials, and that equals savings
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Problems
Needle Free Injectors however…
are more expensive, for example:
Biojector® 2000 Injector $1200.00
Single use, sterile, disposable needle-free
syringes $200.00 (100 syringes per box)
Box of CO2
power cartridges $8.00
(10 CO2
cartridges per box)
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Conclusion
Recap:
Hypodermic Needles
difficult to master (training)
not always effective
safety issues (stick injuries, reuse)
disposal issues
just not well liked (needlephobia)
inexpensive
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Conclusion
Recap:
Needle Free Injectors
safe & sterile
use existing meds & new developments
less medicine required
reliable depth of penetration
efficient use of medication
patients like them and use them (self treatment)
not inexpensive
Introduction Current Ideal Proposed Conclusion

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Needle Free Injections
Conclusion
Conclusion:
Needle Free Injectors are more reliable, easier to
use, more efficient, much safer and have no
disposal problems. Acceptance by patients,
continuing developments and lowering costs all
make needle free systems the best method for
vaccinations, insulin self-treatments, and large or
small scale inoculations.
Introduction Current Ideal Proposed Conclusion

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Needle Free Injection Technology
Thank you