This document discusses fibro-osseous lesions and cherubism. It notes that fibro-osseous lesions involve the replacement of normal bone with collagen fibers and fibroblasts containing mineralized substance like bone or cementum. Cherubism is described as a benign hereditary condition of the maxilla and/or mandible seen in children under 5, causing fullness of the jaws and cheeks with upward gaze. Cherubism is usually an autosomal dominant disorder with higher penetrance in males.

1. Ahmed Ali Al-Asmari

2. Introduction
 Differences remain in the classification
and diagnosis of fibro-osseous disease.
 There is a general consensus that the
common entity for all of the lesions.

3. ...CONT
 is the replacement of normal bone with a
tissue composed of collagen fibers and
fibroblasts that contain varying amounts
of mineralized substance, which can be
either bone or cementum-like material.

4. Fibrous Dysplasia

5. Cherubism:
 is a benign hereditary condition of the
maxilla and/or mandible, usually found in
children by 5 years of age. The term
cherubism has been used to describe
patients with cherubic facies of marked
fullness of the jaws and cheeks and
upwardly gazing eyes.


6. ...CONT
 Cherubism usually occurs as an autosomal-
dominant disorder, with 100% penetrance
in males and 50% to 75% penetrance in
females, with a 2-to-1 male predominance

7. cherubism

8. REFERENCE
Joseph A. Regezi , James J. Sciubba , and
Richard C.K. Jordan , Oral Pathology :
Clinical Pathologic Correlations , 5th ed 2007 ,
Ch. 15 , P.1042
g Michael Miloro, PETERSON‘ PRINCIPLES OF
ORAL AND MAXILLOFACIAL SURGERY,
Second Edition, ch:31 p:592