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2.2  Biological  (Molecular and Cellular) Effects of Ionizing Radiation Assoc.Prof. Bengül Günalp, MD IAEA Expert
The Effects of Radiation on the Cell at the Molecular Level ,[object Object],[object Object],[object Object],[object Object]
Direct Effects ,[object Object]
Indirect Action ,[object Object],[object Object]
Indirect Action- Radiolysis of Water ,[object Object],[object Object],[object Object],[object Object],H-O-H    H +  + OH -  (ionization) H-O-H    H 0 +OH 0  (free radicals)
Indirect Action ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Indirect Action - The Lifetimes of Free Radicals ,[object Object]
Indirect Action- Free Radicals ,[object Object],[object Object]
BIOCHEMICAL REACTIONS WITH IONIZING RADIATION ,[object Object],[object Object],I  I S - AT - S I  I P   P I  I S - CG - S I  I P   P I  I S - GC - S I  I P   P I  I S - TA - S I  I
BIOCHEMICAL REACTIONS WITH IONIZING RADIATION-DNA DAMAGE ,[object Object],[object Object]
BIOCHEMICAL REACTIONS WITH IONIZING RADIATION-DNA DAMAGE ,[object Object],[object Object]
BIOCHEMICAL REACTIONS WITH IONIZING RADIATION-DNA DAMAGE ,[object Object],[object Object]
BIOCHEMICAL REACTIONS WITH IONIZING RADIATION-DNA DAMAGE ,[object Object]
Radiation Induced Chromosome Damage ,[object Object]
Radiation Induced Chromosome Damage ,[object Object]
Radiation Induced Membrane Damage ,[object Object]
Cell Cycle ,[object Object],[object Object],[object Object],[object Object]
Cell Cycle ,[object Object],[object Object]
Cell Cycle ,[object Object],[object Object]
Cell Cycle ,[object Object],[object Object]
Bergonié-Tribondeau Low ,[object Object],[object Object],[object Object],[object Object]
Radiosensitivity ,[object Object],[object Object]

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Biologicaleffectsofionizingradiation

  • 1. 2.2 Biological (Molecular and Cellular) Effects of Ionizing Radiation Assoc.Prof. Bengül Günalp, MD IAEA Expert
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