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New suggested treatment of
 Definition
 Symptoms
 Causes
 Risk factors
 Complications
 Mechanism of vitamine D production
 Mechanism of rickets
 Present treatment
 My suggestion
 Rickets is the softening and weakening of
bones in children, usually because of an
extreme and prolonged vitamin D deficiency.
 Delayed growth
 Pain in the spine, pelvis and legs
 Muscle weakness
 Bowed legs
 Thickened wrists and ankles
 Breastbone projection
Deficiency in
 Vitamin D
 Calcium
 phosphorous
 Age
 Dark skin
 Premature birth
 Anti-seizure medications
 Exclusive breast-feeding.
 If left untreated, rickets may lead to:
 Failure to grow
 Abnormally curved spine
 Skeletal deformities
 Dental defects
 Seizures
 vitamin D and calcium supplements
 Surgical and other procedures
 During breast feeding give oral vitamin D
daily(400 IU drops)
 Increase the activity of 1 α hydroxylase
 Decreased the activity of 24 hydroxylase
 Rocaltrol
Which is commonly used in managment of
hyperparathyriodism
Also enhances calcium absorption
 Calderol
commonly used as hypoparathyroid agents
in some areas also used as vitamin d in the
treatment of rickets
 PTH increases the activity of 1-α-
hydroxylase enzyme, which converts 25-
hydroxycholecalciferol to 1,25-
dihydroxycholecalciferol, the active form
of vitamin D.
 We can increase the production of parathroid
hormone
 http://www.mayoclinic.com
 http://www.betterhealth.com
 http://www.rxlist.com
 Journal of immunology Baltimore,Md:1950
By ifsha akhlaq

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By ifsha akhlaq

  • 2.  Definition  Symptoms  Causes  Risk factors  Complications  Mechanism of vitamine D production  Mechanism of rickets  Present treatment  My suggestion
  • 3.  Rickets is the softening and weakening of bones in children, usually because of an extreme and prolonged vitamin D deficiency.
  • 4.  Delayed growth  Pain in the spine, pelvis and legs  Muscle weakness  Bowed legs  Thickened wrists and ankles  Breastbone projection
  • 5. Deficiency in  Vitamin D  Calcium  phosphorous
  • 6.  Age  Dark skin  Premature birth  Anti-seizure medications  Exclusive breast-feeding.
  • 7.  If left untreated, rickets may lead to:  Failure to grow  Abnormally curved spine  Skeletal deformities  Dental defects  Seizures
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.  vitamin D and calcium supplements  Surgical and other procedures
  • 14.
  • 15.  During breast feeding give oral vitamin D daily(400 IU drops)  Increase the activity of 1 α hydroxylase  Decreased the activity of 24 hydroxylase
  • 16.  Rocaltrol Which is commonly used in managment of hyperparathyriodism Also enhances calcium absorption
  • 17.  Calderol commonly used as hypoparathyroid agents in some areas also used as vitamin d in the treatment of rickets
  • 18.  PTH increases the activity of 1-α- hydroxylase enzyme, which converts 25- hydroxycholecalciferol to 1,25- dihydroxycholecalciferol, the active form of vitamin D.
  • 19.
  • 20.  We can increase the production of parathroid hormone
  • 21.  http://www.mayoclinic.com  http://www.betterhealth.com  http://www.rxlist.com  Journal of immunology Baltimore,Md:1950