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Client Services
     Presentation
Sample Accession: Pre- to Post- Sale
What is Client Services?
• A correspondent who provides information
  and resources on genetic testing
  – Performed or Scheduled to be Performed
• A correspondent between the client and the
  remainder of the company
  – Operations
  – Financial
  – Executive
  – Medical Director
Client Services Goals
1.   Information Resource for Client
2.   Approachable and Friendly Attitude
3.   Exude Professionalism
4.   Information Resource for Company on Client
     Opinions and Comments
Client Services Needs
• Client Services needs to have:
   – CRM system
      • Allow for tracking of all communication systems
   – Communication Tools
      • Landline Phone
      • E-mail
      • Fax
   – Access to LIMS system
      • Determine where samples are
   – Access to Financial Services
      • Determine costs and insurance claim resolutions
• It would be nearly impossible to perform Client
  Services virtually without all of these capabilities
Who is a Client for Genetic Testing?
•   Genetic Counselor
•   Physician
•   Nurse Coordinator
•   Laboratory / Sendout Coordinator
•   Patient

The verbage for each client can be
 dramatically different depending on
 the situation.
Client Services is your front line
World-Class Service
• “World-Class Service” is a potential model for Client
  Services to utilize in their operations.
• "World Class Service" is a term which means that you
  anticipate the needs of your customers before they actually
  have the need. In order to do this, you must intensely study
  your customers and employees to see where

       a) your employees fail your customers,
       b) your services or products fail your customers, and
       c) how your customers change over time.


• Only by having this knowledge can you create a business
  plan that completes the prerequisites of world class
  service.
World-Class Service Example #1 –
          Action – Reaction
• Nurse Coordinators and phlembotomists often
  call Client Services to ask about blood draw
  tube type – Reason: paperwork containing
  information is in doctor’s office, not with
  nurse – Created small adhesive on inside of
  specimen kit which indicates draw tube type
World-Class Service Example #2 –
           Action – Reaction
• Preliminary report explanation –
  preliminary reports still lack
  several amplicons
   – Issue: Nurse / Doctor
     understanding may be difficult
     because genetic testing is different
     from other clinical testing
   – Use Scratch Ticket analogy –
     unable to change information on
     ticket – and information given will
     not change – more time needed to
     fill in gaps.
World-Class Service Example #3 –
          Action – Reaction
• Physician requests a genetic test which is not
  currently offered by the facility
• Issue: Testing selection is not offered by
  facility
• Provide information of potentially where test
  can be performed even if direct competitor
  – Client will view you as a resource plus provide
    information of what customer desires are
Client Service Correspondence
      •   Phone
      •   Mail Correspondence
      •   Fax
      •   E-mail

The level and type of communication varies
  dramatically and differently depending on
  the medium used especially when
  considering sensitive client information
Client Services and HIPAA
• A goal of Client Services is to be resourceful
• A goal of Client Services is to protect patient’s PHI
• The nature of genetic testing involves the
  understanding of parental information at times
Client Services Do’s & Don’ts
• Do:
  – Provide a resource for understanding genetic
    testing – even in cases where it may not directly
    help the company
  – Answer questions before even asked by clients
• Don’t:
  – Provide results to the client directly
     • Possible interpretation issues may occur
  – Sell
How does Client Services help the
             company?
• Interact with the customer in a resourceful
  manner
• Provide information of correspondence to track
  trending of samples and comments – typically
  through a CRM
• Provide input into operations how to efficiently
  handle samples
  – Flag important samples: STAT samples, Business
    Objective Samples, etc.
  – Flag lagging samples to possible finish or provide
    feedback
High Call Volume versus Growing Sales
      Client Services Call Volume
400                                 • Depending on ongoing
350
                                      interactions during the
                                      year, call volume can
300                                   vary.
250                                 • Particular actions
200
                                      performed one month
                                      can reverberate
150                                   several months later
100                                 • Oscillations in call
                                      volume should be
 50
                                      tracked, but not
  0                                   misconstrued.
High Call Volume versus Growing Sales
      Client Services Call Volume
400                                          • Depending on ongoing
350
                                                 interactions during the
                                                 year, call volume can
300                                              vary.
250                                          • Particular actions
                               Is this growing sales or just
                               a Client Services backlog?
200
                                                 performed one month
                                                 can reverberate
150                                              several months later
100                                          • Oscillations in call
                                                 volume should be
 50
                                                 tracked, but not
  0                                              misconstrued.
Importance of CRM
• CRM provides cataloging of all Client Services action on
  day-to-day basis
• Importance to log all information, however banal, with
  understanding that message would be read 3-18
  months later by another party.
• Importance for Management to establish uniform
  tracking method for all Client Services members to
  adhere – very high “learning curve”
• CRM provides “10,000 ft” view of operations through
  dashboards and other indicators
   – Importance of management to utilize and exploit CRM
     system to its fullest
CRM Primer
• CRM is a tool which provides organization to the
  Client Services representative by logging every
  correspondence – e-mail, phone, fax into the
  system
• Typically CRM is a shell program towards the e-
  mail system, so manual integration is crucial
• Faxes should be scanned in, then attached and
  cataloged into the system
• Every phone conversation must be logged in and
  a fair representation of time spent should be
  performed
How did that phone call take 10
               minutes?
• Scenario: Call received from nurse, unsure of
  ordering physician identity, needs report
• Receive call: Identify nurse from particular
  hospital, identifies patient, identifies needs
  report sent to particular fax number – this is
  physically done on scratch paper
• Post call: Using patient name, identify original
  ordering physician on order form, log
  information, print report, print appropriate cover
  sheet
How did that phone call take 10
           minutes? continued
• Phone call: 3 minutes
• Post-phone call CRM activities: 4 minutes
  –   Look at patient documents
  –   Identify doctor
  –   Find doctor entry in CRM
  –   Log phone call into CRM
• Post-phone call: 3 minutes
  –   Print report
  –   Print coversheet
  –   Send fax
  –   Confirm fax reception
Understanding Your Customer
• Keeping with “World-Class Service”, understanding
  your customer is tantamount to anticipating their
  desires.
• Although stereotyping may be considered crude, it
  helps follow a heuristic about what concerns a
  customer may have.
• Currently, Client Services faces two types of customers
  Cardiologist and Immunologists which have stark
  contrasts in their interactions.
• Understanding customer desires and worries and
  acting BEFORE it happens makes for good Client
  Services
Typical Pediatric Allergy/Immunology
                  Department
Medical Director




Staff Physicians




Fellows




Nurse Coordinators
Any Combination of Relationships
                     Possible
Medical Director




Staff Physicians




Fellows




Nurse Coordinators
Coordination between Departments
              may be necessary
                     Immunology   BMT Group
Medical Director
                     Department




Staff Physicians




Fellows




Nurse Coordinators
Typical Hospital-Based Cardiology
                       Department


Hospital
Administration
(True Decision Maker)




Medical Director

Staff Physicians

 Fellows


Nurse Coordinators
Typical Suburban Cardiology Practice

                     Appointed Leader




Staff Physicians
(Decision Makers)




Nurse Coordinators
Types of Questions answered in
              Client Services
• Technical Background Questions
   – How is my sample processed?
• Sample Completion Issues
   – Where is my sample?
• Financial Issues
   – How much will this cost me?
• Logistics Issues
   – How do I provide a sample for testing?
• Report Interpretation Issues
   – What does this on the report mean?
• Report Feedback Issues
   – How do I act accordingly with the results given?
Comparison of Customer type and
                 typical questions
             Report Interpretation
Does not                                                                         Complete
understand                                                                       Comprehension

                    C a r d i o l o g i s t s        Immunologists
             Financial Concerns to Patients
Little                                                                           Very Concerned
Concern
             Immunologists                                     Cardiologists

             Beliefs in Genetic Testing and Clinical Outcome
No Belief                                                                        Strongest Belief


                              Cardiologists                      Immunologists
Comparison of Customer type and
               typical questions
             Report Interpretation
Does not                                                                         Complete
understand                                                                       Comprehension

                     C a r d i o l o g i s t s       Immunologists

   Even if an immunologist does not Patients
               Financial Concerns to
   completely understands the genetics
Little                                                                           Very Concerned
Concern an outcome, the physician
   behind
   knows to act in a very strong manner
                Immunologists                                  Cardiologists

             Beliefs in Genetic Testing and Clinical Outcome
No Belief                                                                        Strongest Belief


                               Cardiologists                     Immunologists
Case Study AA09001828
• New Physician to ordering Genetic Testing
• Consider ordering Wiskott-Aldrich Syndrome
  testing (Immunology)
• Briefly mentioned extensive history treating
  patient – see as next step in determine best
  course of treatment
• Using this example because somewhat good
  flow with few “hiccups”
Case Study AA09001828 – Initiation –
                 CRM Log
•   2/26/2009 11:13 AM        10 minutes
•   Call Received      WAS Testing
•   Call received from Lab Tech Gerry Linden
•   understands needs 2-ml EDTA tube of blood
•   understands can pre-qualify patient from before
•   understands sending specimen kit to Alexandria office
•   confirmed location of alexandria office
•   works for Robert Dobrzynski
•   17 yM WAS
•   needs kit on Monday
•   send specimen kit to 5226 Dawes Avenue, Alexandria, VA
    22311
Case Study AA09001828 – Initiation –
              continued
• Goal is to understand situation
  – New Physician possibly ordering WAS test
• Determine who is calling
  – Gerry Linden
• Determine what is role of person calling
  – Lab Tech / Nurse Coordinator
• Determine next action items to work on
  – Send specimen kit to confirmed address
Case Study AA09001828 – Website
            Snapshot
Case Study AA09001828 – Website
          Snapshot – continued
•   Based in Northern Virginia area
•   Three practices
•   Four Physicians
•   Not accustomed to ordering genetic testing
•   Not a “Center of Excellence” location
Case Study AA09001828 – Pre-sale –
      follow-through – CRM Log
• 3/4/2009 3:27 PM 5 minutes Call Received
      WAS Testing
• Call received from Gerry
• indicated that will be sending paperwork with
  patients
• will draw patient on Tuesday
Case Study AA09001828 – Pre-sale –
    follow-through - financials – CRM Log
•   3/4/2009 4:17 PM 10 minutes
•   Call Received      WAS testing
•   Call received from mother of patient name given
•   703-815-3561
•   Patient name given
•   DOB: 4/23/1991
•   AETNA ID: W1201 43172
•   Group: 630891-10000
•   Providers # 888-802-3862
•   PO Box 9612804 El Paso, TX
•   will call back mother
Case Study AA09001828 – Pre-sale –
follow-through – financials – Insurance
            Determination
Case Study AA09001828 – Pre-sale –
    financials – Insurance Determination –
                    follow-up
•   3/4/2009 5:06 PM 10 minutes
•   Call Completed      WAS Testing
•   Spoke with Mother name given
•   send pre-auth info to Home Fax
•   Fax 703-815-5441


Sample received on 3/18/2009
Case Study AA09001828 – Pre-sale –
        financials – Final Issue
• 3/23/2009 1:21 PM 10 minutes
• Call Completed
• AA09001828 - billing issue Spoke with mother of
  patient
• took CC information
• VISA XXXX 1548 exp 02/12

After accession has been provided refer to
  FULL accession only in ALL transactions
Case Study AA09001828 – Sample in-
             process
Case Study AA09001828 – Report
               Release
• Report released on 4/26/2009
• 1 Disease-causing published variant found
• Need to provide list of references in relation
  to disease variant
Case Study AA09001828 – Report
            Release – follow-up
• 4/27/2009 2:48 PM 10 minutes
• Call Completed AA09001828 - report - follow-up

•   Spoke with receptionist
•   transferred to Dr. Dobrzynski receptionist
•   Spoke to receptionist
•   possibly speak with Dr. Dobrzynski
•   spoke with Dr. Dobrzynski
•   BPDobrzynski@hotmail.com
Case Study AA09001828 – Report
    Release – follow-up - continued
• Goal is to follow-up with Doctor
• Provide Medical Director direct line to physician
  directly
   – Indicated to Doctor that Medical Director can follow-
     up with any questions
• Provide list of variants which have been
  published
   – Direct links to Pubmed
• There is never a discussion about the results of
  the report
Case Study AA09001828 – Report
      Release – follow-up - continued
•   4/28/2009 10:56 AM        10 minutes
•   Call Completed
•   AA09001828 - report - follow-up
•   Spoke to receptionist
•   transferred to Gerry Linden
•   << on hold for some time >>
•   spoke with Gerry
•   asked to send results to patient immediately.
Case Study AA09001828 – Timeline
• Took 44 days from initial inquiry to final follow-up
• Not continuous work – need to take diligent
  notes to ensure continuity in process
Case Study - AA09001711
• Experienced Cardiologist with prior ordering
  history of genetic testing – Robert Bonow
• Physician is in Chicago area
• Cardiologist works closely with Nurse
  Coordinator Edith and Administrative
  Assistant Angela
• Cardiologist’s group utilizes e-mail extensively
• Example of Index and Respective Family
  Testing
AA09001711 – Physician Practice Hierarchy


                       Physician
                                           Important that all
                                           members be informed
                                           of all on-going actions

   Nurse Coordinator



                                   Administrative Assistant
AA09001711 – Physician Practice Hierarchy
                    Client Services View




Nurse Coordinator        Physician         Administrative Assistant



In terms of Client Services, all members are equal
AA09001711 – Physician Practice Hierarchy
                                 Client Services View




Nurse Coordinator               Physician                    Administrative Assistant
1. Partial-to-Full Decision     1. Full decision maker       1. Limited Decision Maker
   Maker                        2. Extreme Time              2. No Time Restraints
2. Limited Time Restraints         Restraints                3. No understanding of clinical
3. Decent understanding         3. Decent-to-Full               versus genetic diagnosis
   of clinical versus genetic      understanding of
   diagnosis                       clinical versus genetic
                                   diagnosis

Client Services exploits each office member to their fullest
Case Study – AA09001711
• Index Patient is located some distance from
  physician’s office
• Patient has several clinical issues to warrant
  genetic testing for greater understanding
• Patient’s mother recently passed away
Limited Family Pedigree




AA09001966   AA09001963   AA09001829




                                 AA09001711
                                  (index)
AA09001711 – Sample Reception
      - operation communications
• 2/9/2009 3:55 PM 0 minutes          E-mail Attachment
       Subject: Sample rec'd today
• Hi Al,
• Please contact Dr. Bonow’s office regarding index patient
  name , DOB: 6/12/76.
• Dr. B. checked off reflexive test, 190350, and kinda marked
  the PRKAG2 and LAMP2 genes (so perhaps he also wants
  the metabolic panel?).
• Please confirm by phone or e-mail.

• Thanks!
• Liz
AA09001711 – Sample Reception
• Sample received from Dr. Bonow on 2/9/2009
• Communication received from operations during
  in-processing procedure
• Needed to verify testing information before
  entered into LIMS system
• Critical information (verify test code) otherwise
  problems for LIMS system
• Client Services can inquire about issue directly or
  provide information to salesperson to provide
  scenario for more sales and client interaction
AA09001711 - Payment Issue –
         Salesperson notes
• 2/12/2009 11:54 AM
• Dr. Bonow will speak with the family name
  family about the $2000 deductible and he or
  they will call me back. Dr. Bonow indicates the
  family is particularly concerned with young
  patient name's sister and assumes they will
  pay if needed. Also, the test code Dr. Bonow
  wants for patient name is 190350. Bonow is
  very happy with CRLG
AA09001711 – Payment Issues
• Salesperson spoke with patient on 2/12/2009
• Communicated with Client Services that
  patient understands payment responsibilities
• Sample initiated by Client Services on
  2/12/2009
• Turn-Around Time Clock initiated by LIMS
  system
AA09001711 – Sample Status Inquiries
• Patient’s health situation critical
• Numerous inquiries both by telephone and e-
  mail about status of patient’s sample
AA09001711 – Sample Inquiry continued
• 2/24/2009 1:54 PM         0 minutes E-mail Sent
       Subject: Correlagen Diagnostics: AA09001711
   status
Hello Edith-
In regards to patient blinded patient name, there are
   seven remaining amplicons of the 113 performed. I
   anticipate the report should be released to you by the
   beginning of next week.
Please feel free to contact me with any additional
   questions.
Sincerely,
-Al
AA09001711 – Sample Inquiry continued
3/6/2009 12:05 PM    0 minutes E-mail
  Attachment    Subject: Correlagen Diagnostics:
  AA09001711 status anything yet?? Edie

Edith A. Pacheco, RN
Lead Cardiology Nurse
Bluhm Cardiovascular Institute of Northwestern
Tel 312.695.1796
AA09001711 – Preliminary Report
              Release
• In process of sample analysis, critical mutation
  found in gene analysis to warrant early
  preliminary report to raise caution to ordering
  physician.
• Understanding must be provided to all that
  final report to add to preliminary report, but
  will not change outcome most likely.
AA09001711 –
              Preliminary Report e-mail
• 3/6/2009 1:20 PM         0 minutes E-mail Sent
       Subject: Correlagen Diagnostics: AA09001711
   status
Hello Edith-
I have a preliminary report today which I will send to you
   immediately to your (312) 695-1434 number. I
   anticipate the remainder should be available next
   week.
Sincerely,
-Al
• Same e-mail sent to all three members of physician
   team
AA09001711 – preliminary report –
          related references
• 3/9/2009 2:44 PM 0 minutes             E-mail Sent     Subject:
   Correlagen Diagnostics: AA09001711: TNNT2 c.487 References
        Dear Dr. Bonow-
As per request of Edith Pacheco, please find enclosed references for
your review. The reference sheet has dynamic hyperlinks to the
respective PUBMED publications for your access.
Please feel free to contact me with any additional questions or
requests.

Sincerely,
-Al
AA09001711 – related references
AA09001711 – related references -
            comments
• Acrobat document which has list of references
  which have direct access to Hyperlinked PUBMED
  references per variant found
• Provides a higher lever of understanding for
  physicians to instantly research publically
  available literature
• Document is not specific to patient
• Document is specific to references in literature
  only – no internal data (blinded or not blinded) is
  provided
AA09001711 – preliminary report –
          Action-Reaction
• 3/9/2009 1:14 PM 10 minutes Call Received
       AA09001711 - family testing
• Call received from Edith Pacheco
• indicated mother of patient has deceased from possible
  HCM - however unsure
• needs to know if perform testing on deceased human
  tissue or blood
• will provide blood from deceased
• Salesperson will provide special family pricing to all
  members
• Edith to make several photocopies of requisition forms for
  family distribution.
AA09001711 – family testing logistics
• 3/16/2009 4:02 PM          5 minutes Call Received
       AA09001711 - family testing
• Call received from Lake County Coroner's Office Deputy
  officer name
• 847-377-2200
• mentioned had whole blood - frozen blood - collected
  in plastic vial - sodium fluoride as preservative –
• prevent clotting
• has multiple DNA standard cards
• would be able to provide some blood
AA09001711 – family sample reception
•   3/18/2009 2:50 PM        0 minutes           E-mail Sent          Subject:
    Correlagen Diagnostics: partial patient name
    Dear Dr. Bonow-
Thank you for choosing Correlagen Diagnostics as your genetics
laboratory service provider.

This e mail is confirmation that we have received your specimen(s) dated
3/18/09, and we are in the process of reviewing the documentation and
specimen as instructed. We will contact you immediately in the event we
are missing any required documentation or if the sample provided is not
adequate for testing. The corresponding accession number given to your
blood sample is AA09001829.

Please feel free to call our Client Services Manager, Al Gunduz, at
781-647-0604 x261 with any additional information you may need or
questions you might have.
AA09001711 – report inquiry
• 3/26/2009 12:22 PM 0 minutes           E-mail Attachment
        Subject: Accession #: AA09001711
• Hi Al
We received a fax copy of the genetic report for accession #
    AA09001711.
Dr. Bonow would like to know if this result really is the result of the
patient's deceased mother or more results for the patient himself?
Thanks
AD

Angelene Delk
Administrative Assistant to Robert Bonow, MD
Bluhm Cardiovascular Institute of Northwestern
AA09001711 – report inquiry - response
• 3/26/2009 12:33 PM                 0 minutes E-mail Sent Subject: Accession #: AA09001711
• Good Morning Angelene-
The patient report that arrived yesterday is the final report to patient
partial patient name. The initial report sent on March 9th, 2009 was the preliminary
report sent by the Medical Director due to the significance of the
variant found.

The sample of the patient’s mother is accession #AA09001829.

Please feel free to contact me if you have any additional questions.

Sincerely,

-Al

Al Gunduz | Manager, Immunology and Client Services | Correlagen
Diagnostics, Inc. | 781-647-0604 x261
AA09001829 – logistics background
• Patient AA09001829 is deceased and does not
  have effective insurance coverage
• Issue of sample testing payment is in question
• Initially determine from insurance of deceased
  that if coverage possible
• Learned coverage termed at date of death
AA09001829 – payment inquiry
• 4/13/2009 1:04 PM 10 minutes      Call
  Received
• AA09001829 - payment issue
• Received call from son of patient
  (AA09001711)indicated no coverage for
  patient
• offered $100.00 deal
• provided M/C XXXX 2973 exp
AA09001829 – family testing
•   4/28/2009 9:19 AM 10 minutes
•   AA09001829 - family testing
•   Call received from patient name given
•   sister of AA09001829
•   left VM
•   provided phone 847-212-5166
AA09001829 – family testing – further inquiry
•   4/28/2009 9:56 AM         15 minutes
•   Call Received      AA09001829 - family testing
•   Call received from patient full name given
•   sister of AA09001828
•   DOB date given
•   BC/BS NY
•   ID EQP80090655
•   Group 294572A11
•   # 800-582-4489
•   PO Box 5009, Middletown, Ny
•   Husband name with different surname given
AA09001829 – testing logistics
• Call received from Nurse Edith
• Indicated wanted to simplify paperwork
• Indicated to Edith will provide specialized
  paperwork specific to this family’s variant
  only.
• Sent 3 Specimen Kits with specialized
  paperwork
AA09001829 – family testing – other sister
•    4/28/2009 12:48 PM     15 minutes        Call Received   AA09001892 -
     family testing
• Call received from patient ‘s sister
• 314-469-5922
• not aware of results for AA09001892 - DOE 1/31/2009
• provided address
• Patient name given
13215 Hawkshead Court
St. Louis, MO 63131
• DOB date given
• UHC
• ID: 903631475
• Group: 714084
Subscriber: patient
• # 877-842-3210
• Providers Address: SLC, UT
AA09001829 – family testing e-mail
•   4/28/2009 5:28 PM        0 minutes          E-mail Sent          Subject:
    Correlagen Diagnostics: AA09001829 - family testing
•   Hello Edith-

The first two family members have contacted me about family testing.
You should received the package I sent tomorrow (if not today) with the
special forms specific to this family. I have provided insurance
coverage information to you for the first family member scheduled to
visit your office next week.

If you could please attach the following forms with her paperwork, this
will make the process smoother.
Please feel free to contact me if you have any additional questions or
requests.
Sincerely,
-All
AA09001966 family testing      –                                     –   receipt e-mail

•   5/12/2009 2:55 PM         0 minutes          E-mail Sent        Subject:
    Correlagen Diagnostics: Jan R. sample received         Dear Ms. Pacheco-

•   Thank you for choosing Correlagen Diagnostics as your genetics
•   laboratory service provider.

•   This e mail is confirmation that we have received your specimen(s) dated
•   5/12/2009, and we are in the process of reviewing the documentation and
•   specimen as instructed. We will contact you immediately in the event we
•   are missing any required documentation or if the sample provided is not
•   adequate for testing. The corresponding accession number given to your
•   blood sample is AA09001966.

•   Please feel free to call our Client Services Manager, Al Gunduz, at
•   781-647-0604 x261 with any additional information you may need or
•   questions you might have.
AA09001829 – family testing
• 4/28/2009 12:48 PM 15 minutes Call Received
      AA09001892 - family testing
• Call received from patient other sister
• Home phone number
• not aware of results for AA09001892 - DOE
  1/31/2009
• provided address
• provided insurance information
• Indicated will be going to physician not in Chicago
  area
AA09001829 – family testing
• 4/29/2009 3:22 PM 10 minutes       Call
  Completed
• AA09001829 - request to share information

• Spoke to Angie Delk (coordinator of Chicago
  physician)
• indicated okay to share results with patient
• will send e-mail confirming this.
AA09001829 – family testing
• 4/29/2009 3:28 PM 10 minutes         Call
  Completed AA09001829 - family test
• Spoke to receptionist Laurie
• indicated nurse to contact me
• fax send to 314-996-3268
• ATTN: Dr. Mankowitz - nurse Gerri / Lisa
AA09001829 – family testing
• 4/30/2009 9:53 AM 10 minutes Call Received
       AA09001829 - family testing
• Call received with Gerri
• gburke@im.wustl.edui
• ndicated to send list of references
• indicated that patient has specimen kit & pre-
  paid mailer
• provided contact information
• send list of references to Dr. Mankowitz and Gerri
  Burke
AA09001829 – family testing
•   4/30/2009 10:10 AM       0 minutes        E-mail Attachment Subject:
    Correlagen Diagnostics: AA09001829 / AA09001711 - related references
•   Good Morning Gerri-

•   It was excellent speaking with you this morning about your patient Second sister .
    Please find attached references in regards to this variant.

•   The references are interactive in that they automatically link to the
•   corresponding PUBMED webpage to review each publication independently.

•   Please feel free to contact me with any additional questions or requests
•   on this matter.

•   Sincerely,
•   -Al
AA09001829 – family testing
• 4/30/2009 3:40 PM        0 minutes     E-mail Attachment
      Subject: Correlagen Diagnostics: AA09001829 /
  AA09001711 - related references        Thanks

• The sister, my patient will be coming in for a gene study.

• I would like to test her for the same gene.

• Can you please send us the paperwork and tell us how
  much it will cost the patient

Sample received on 5/8/2009 for second sister
AA09001963 – family testing
• 5/12/2009 10:30 AM         10 minutes Call
  Completed AA09001963 - family testing -
  314-469-5922
• Spoke to patient
• not to be billed to insurance
• VISA XXXX 6812 exp 07/11
• final $100.00
Limited Family Pedigree




AA09001966   AA09001963   AA09001829




                                 AA09001711
                                  (index)
Grand Timeline
Grand Timeline - Full Information
Correspondence Count
• Number of Correspondences (phone, e-
  mail, fax) with each particular accession
  – AA09001711 (index): 97
  – AA09001829: 158
  – AA09001963: 11+
  – AA09001963: 18+
• Total as of 5/21/2009 for this family: 284

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Client services overview

  • 1. Client Services Presentation Sample Accession: Pre- to Post- Sale
  • 2. What is Client Services? • A correspondent who provides information and resources on genetic testing – Performed or Scheduled to be Performed • A correspondent between the client and the remainder of the company – Operations – Financial – Executive – Medical Director
  • 3. Client Services Goals 1. Information Resource for Client 2. Approachable and Friendly Attitude 3. Exude Professionalism 4. Information Resource for Company on Client Opinions and Comments
  • 4. Client Services Needs • Client Services needs to have: – CRM system • Allow for tracking of all communication systems – Communication Tools • Landline Phone • E-mail • Fax – Access to LIMS system • Determine where samples are – Access to Financial Services • Determine costs and insurance claim resolutions • It would be nearly impossible to perform Client Services virtually without all of these capabilities
  • 5. Who is a Client for Genetic Testing? • Genetic Counselor • Physician • Nurse Coordinator • Laboratory / Sendout Coordinator • Patient The verbage for each client can be dramatically different depending on the situation.
  • 6. Client Services is your front line
  • 7. World-Class Service • “World-Class Service” is a potential model for Client Services to utilize in their operations. • "World Class Service" is a term which means that you anticipate the needs of your customers before they actually have the need. In order to do this, you must intensely study your customers and employees to see where a) your employees fail your customers, b) your services or products fail your customers, and c) how your customers change over time. • Only by having this knowledge can you create a business plan that completes the prerequisites of world class service.
  • 8. World-Class Service Example #1 – Action – Reaction • Nurse Coordinators and phlembotomists often call Client Services to ask about blood draw tube type – Reason: paperwork containing information is in doctor’s office, not with nurse – Created small adhesive on inside of specimen kit which indicates draw tube type
  • 9. World-Class Service Example #2 – Action – Reaction • Preliminary report explanation – preliminary reports still lack several amplicons – Issue: Nurse / Doctor understanding may be difficult because genetic testing is different from other clinical testing – Use Scratch Ticket analogy – unable to change information on ticket – and information given will not change – more time needed to fill in gaps.
  • 10. World-Class Service Example #3 – Action – Reaction • Physician requests a genetic test which is not currently offered by the facility • Issue: Testing selection is not offered by facility • Provide information of potentially where test can be performed even if direct competitor – Client will view you as a resource plus provide information of what customer desires are
  • 11. Client Service Correspondence • Phone • Mail Correspondence • Fax • E-mail The level and type of communication varies dramatically and differently depending on the medium used especially when considering sensitive client information
  • 12. Client Services and HIPAA • A goal of Client Services is to be resourceful • A goal of Client Services is to protect patient’s PHI • The nature of genetic testing involves the understanding of parental information at times
  • 13. Client Services Do’s & Don’ts • Do: – Provide a resource for understanding genetic testing – even in cases where it may not directly help the company – Answer questions before even asked by clients • Don’t: – Provide results to the client directly • Possible interpretation issues may occur – Sell
  • 14. How does Client Services help the company? • Interact with the customer in a resourceful manner • Provide information of correspondence to track trending of samples and comments – typically through a CRM • Provide input into operations how to efficiently handle samples – Flag important samples: STAT samples, Business Objective Samples, etc. – Flag lagging samples to possible finish or provide feedback
  • 15. High Call Volume versus Growing Sales Client Services Call Volume 400 • Depending on ongoing 350 interactions during the year, call volume can 300 vary. 250 • Particular actions 200 performed one month can reverberate 150 several months later 100 • Oscillations in call volume should be 50 tracked, but not 0 misconstrued.
  • 16. High Call Volume versus Growing Sales Client Services Call Volume 400 • Depending on ongoing 350 interactions during the year, call volume can 300 vary. 250 • Particular actions Is this growing sales or just a Client Services backlog? 200 performed one month can reverberate 150 several months later 100 • Oscillations in call volume should be 50 tracked, but not 0 misconstrued.
  • 17. Importance of CRM • CRM provides cataloging of all Client Services action on day-to-day basis • Importance to log all information, however banal, with understanding that message would be read 3-18 months later by another party. • Importance for Management to establish uniform tracking method for all Client Services members to adhere – very high “learning curve” • CRM provides “10,000 ft” view of operations through dashboards and other indicators – Importance of management to utilize and exploit CRM system to its fullest
  • 18. CRM Primer • CRM is a tool which provides organization to the Client Services representative by logging every correspondence – e-mail, phone, fax into the system • Typically CRM is a shell program towards the e- mail system, so manual integration is crucial • Faxes should be scanned in, then attached and cataloged into the system • Every phone conversation must be logged in and a fair representation of time spent should be performed
  • 19. How did that phone call take 10 minutes? • Scenario: Call received from nurse, unsure of ordering physician identity, needs report • Receive call: Identify nurse from particular hospital, identifies patient, identifies needs report sent to particular fax number – this is physically done on scratch paper • Post call: Using patient name, identify original ordering physician on order form, log information, print report, print appropriate cover sheet
  • 20. How did that phone call take 10 minutes? continued • Phone call: 3 minutes • Post-phone call CRM activities: 4 minutes – Look at patient documents – Identify doctor – Find doctor entry in CRM – Log phone call into CRM • Post-phone call: 3 minutes – Print report – Print coversheet – Send fax – Confirm fax reception
  • 21. Understanding Your Customer • Keeping with “World-Class Service”, understanding your customer is tantamount to anticipating their desires. • Although stereotyping may be considered crude, it helps follow a heuristic about what concerns a customer may have. • Currently, Client Services faces two types of customers Cardiologist and Immunologists which have stark contrasts in their interactions. • Understanding customer desires and worries and acting BEFORE it happens makes for good Client Services
  • 22. Typical Pediatric Allergy/Immunology Department Medical Director Staff Physicians Fellows Nurse Coordinators
  • 23. Any Combination of Relationships Possible Medical Director Staff Physicians Fellows Nurse Coordinators
  • 24. Coordination between Departments may be necessary Immunology BMT Group Medical Director Department Staff Physicians Fellows Nurse Coordinators
  • 25. Typical Hospital-Based Cardiology Department Hospital Administration (True Decision Maker) Medical Director Staff Physicians Fellows Nurse Coordinators
  • 26. Typical Suburban Cardiology Practice Appointed Leader Staff Physicians (Decision Makers) Nurse Coordinators
  • 27. Types of Questions answered in Client Services • Technical Background Questions – How is my sample processed? • Sample Completion Issues – Where is my sample? • Financial Issues – How much will this cost me? • Logistics Issues – How do I provide a sample for testing? • Report Interpretation Issues – What does this on the report mean? • Report Feedback Issues – How do I act accordingly with the results given?
  • 28. Comparison of Customer type and typical questions Report Interpretation Does not Complete understand Comprehension C a r d i o l o g i s t s Immunologists Financial Concerns to Patients Little Very Concerned Concern Immunologists Cardiologists Beliefs in Genetic Testing and Clinical Outcome No Belief Strongest Belief Cardiologists Immunologists
  • 29. Comparison of Customer type and typical questions Report Interpretation Does not Complete understand Comprehension C a r d i o l o g i s t s Immunologists Even if an immunologist does not Patients Financial Concerns to completely understands the genetics Little Very Concerned Concern an outcome, the physician behind knows to act in a very strong manner Immunologists Cardiologists Beliefs in Genetic Testing and Clinical Outcome No Belief Strongest Belief Cardiologists Immunologists
  • 30. Case Study AA09001828 • New Physician to ordering Genetic Testing • Consider ordering Wiskott-Aldrich Syndrome testing (Immunology) • Briefly mentioned extensive history treating patient – see as next step in determine best course of treatment • Using this example because somewhat good flow with few “hiccups”
  • 31. Case Study AA09001828 – Initiation – CRM Log • 2/26/2009 11:13 AM 10 minutes • Call Received WAS Testing • Call received from Lab Tech Gerry Linden • understands needs 2-ml EDTA tube of blood • understands can pre-qualify patient from before • understands sending specimen kit to Alexandria office • confirmed location of alexandria office • works for Robert Dobrzynski • 17 yM WAS • needs kit on Monday • send specimen kit to 5226 Dawes Avenue, Alexandria, VA 22311
  • 32. Case Study AA09001828 – Initiation – continued • Goal is to understand situation – New Physician possibly ordering WAS test • Determine who is calling – Gerry Linden • Determine what is role of person calling – Lab Tech / Nurse Coordinator • Determine next action items to work on – Send specimen kit to confirmed address
  • 33. Case Study AA09001828 – Website Snapshot
  • 34. Case Study AA09001828 – Website Snapshot – continued • Based in Northern Virginia area • Three practices • Four Physicians • Not accustomed to ordering genetic testing • Not a “Center of Excellence” location
  • 35. Case Study AA09001828 – Pre-sale – follow-through – CRM Log • 3/4/2009 3:27 PM 5 minutes Call Received WAS Testing • Call received from Gerry • indicated that will be sending paperwork with patients • will draw patient on Tuesday
  • 36. Case Study AA09001828 – Pre-sale – follow-through - financials – CRM Log • 3/4/2009 4:17 PM 10 minutes • Call Received WAS testing • Call received from mother of patient name given • 703-815-3561 • Patient name given • DOB: 4/23/1991 • AETNA ID: W1201 43172 • Group: 630891-10000 • Providers # 888-802-3862 • PO Box 9612804 El Paso, TX • will call back mother
  • 37. Case Study AA09001828 – Pre-sale – follow-through – financials – Insurance Determination
  • 38. Case Study AA09001828 – Pre-sale – financials – Insurance Determination – follow-up • 3/4/2009 5:06 PM 10 minutes • Call Completed WAS Testing • Spoke with Mother name given • send pre-auth info to Home Fax • Fax 703-815-5441 Sample received on 3/18/2009
  • 39. Case Study AA09001828 – Pre-sale – financials – Final Issue • 3/23/2009 1:21 PM 10 minutes • Call Completed • AA09001828 - billing issue Spoke with mother of patient • took CC information • VISA XXXX 1548 exp 02/12 After accession has been provided refer to FULL accession only in ALL transactions
  • 40. Case Study AA09001828 – Sample in- process
  • 41. Case Study AA09001828 – Report Release • Report released on 4/26/2009 • 1 Disease-causing published variant found • Need to provide list of references in relation to disease variant
  • 42. Case Study AA09001828 – Report Release – follow-up • 4/27/2009 2:48 PM 10 minutes • Call Completed AA09001828 - report - follow-up • Spoke with receptionist • transferred to Dr. Dobrzynski receptionist • Spoke to receptionist • possibly speak with Dr. Dobrzynski • spoke with Dr. Dobrzynski • BPDobrzynski@hotmail.com
  • 43. Case Study AA09001828 – Report Release – follow-up - continued • Goal is to follow-up with Doctor • Provide Medical Director direct line to physician directly – Indicated to Doctor that Medical Director can follow- up with any questions • Provide list of variants which have been published – Direct links to Pubmed • There is never a discussion about the results of the report
  • 44. Case Study AA09001828 – Report Release – follow-up - continued • 4/28/2009 10:56 AM 10 minutes • Call Completed • AA09001828 - report - follow-up • Spoke to receptionist • transferred to Gerry Linden • << on hold for some time >> • spoke with Gerry • asked to send results to patient immediately.
  • 45. Case Study AA09001828 – Timeline • Took 44 days from initial inquiry to final follow-up • Not continuous work – need to take diligent notes to ensure continuity in process
  • 46. Case Study - AA09001711 • Experienced Cardiologist with prior ordering history of genetic testing – Robert Bonow • Physician is in Chicago area • Cardiologist works closely with Nurse Coordinator Edith and Administrative Assistant Angela • Cardiologist’s group utilizes e-mail extensively • Example of Index and Respective Family Testing
  • 47. AA09001711 – Physician Practice Hierarchy Physician Important that all members be informed of all on-going actions Nurse Coordinator Administrative Assistant
  • 48. AA09001711 – Physician Practice Hierarchy Client Services View Nurse Coordinator Physician Administrative Assistant In terms of Client Services, all members are equal
  • 49. AA09001711 – Physician Practice Hierarchy Client Services View Nurse Coordinator Physician Administrative Assistant 1. Partial-to-Full Decision 1. Full decision maker 1. Limited Decision Maker Maker 2. Extreme Time 2. No Time Restraints 2. Limited Time Restraints Restraints 3. No understanding of clinical 3. Decent understanding 3. Decent-to-Full versus genetic diagnosis of clinical versus genetic understanding of diagnosis clinical versus genetic diagnosis Client Services exploits each office member to their fullest
  • 50. Case Study – AA09001711 • Index Patient is located some distance from physician’s office • Patient has several clinical issues to warrant genetic testing for greater understanding • Patient’s mother recently passed away
  • 51. Limited Family Pedigree AA09001966 AA09001963 AA09001829 AA09001711 (index)
  • 52. AA09001711 – Sample Reception - operation communications • 2/9/2009 3:55 PM 0 minutes E-mail Attachment Subject: Sample rec'd today • Hi Al, • Please contact Dr. Bonow’s office regarding index patient name , DOB: 6/12/76. • Dr. B. checked off reflexive test, 190350, and kinda marked the PRKAG2 and LAMP2 genes (so perhaps he also wants the metabolic panel?). • Please confirm by phone or e-mail. • Thanks! • Liz
  • 53. AA09001711 – Sample Reception • Sample received from Dr. Bonow on 2/9/2009 • Communication received from operations during in-processing procedure • Needed to verify testing information before entered into LIMS system • Critical information (verify test code) otherwise problems for LIMS system • Client Services can inquire about issue directly or provide information to salesperson to provide scenario for more sales and client interaction
  • 54. AA09001711 - Payment Issue – Salesperson notes • 2/12/2009 11:54 AM • Dr. Bonow will speak with the family name family about the $2000 deductible and he or they will call me back. Dr. Bonow indicates the family is particularly concerned with young patient name's sister and assumes they will pay if needed. Also, the test code Dr. Bonow wants for patient name is 190350. Bonow is very happy with CRLG
  • 55. AA09001711 – Payment Issues • Salesperson spoke with patient on 2/12/2009 • Communicated with Client Services that patient understands payment responsibilities • Sample initiated by Client Services on 2/12/2009 • Turn-Around Time Clock initiated by LIMS system
  • 56. AA09001711 – Sample Status Inquiries • Patient’s health situation critical • Numerous inquiries both by telephone and e- mail about status of patient’s sample
  • 57. AA09001711 – Sample Inquiry continued • 2/24/2009 1:54 PM 0 minutes E-mail Sent Subject: Correlagen Diagnostics: AA09001711 status Hello Edith- In regards to patient blinded patient name, there are seven remaining amplicons of the 113 performed. I anticipate the report should be released to you by the beginning of next week. Please feel free to contact me with any additional questions. Sincerely, -Al
  • 58. AA09001711 – Sample Inquiry continued 3/6/2009 12:05 PM 0 minutes E-mail Attachment Subject: Correlagen Diagnostics: AA09001711 status anything yet?? Edie Edith A. Pacheco, RN Lead Cardiology Nurse Bluhm Cardiovascular Institute of Northwestern Tel 312.695.1796
  • 59. AA09001711 – Preliminary Report Release • In process of sample analysis, critical mutation found in gene analysis to warrant early preliminary report to raise caution to ordering physician. • Understanding must be provided to all that final report to add to preliminary report, but will not change outcome most likely.
  • 60. AA09001711 – Preliminary Report e-mail • 3/6/2009 1:20 PM 0 minutes E-mail Sent Subject: Correlagen Diagnostics: AA09001711 status Hello Edith- I have a preliminary report today which I will send to you immediately to your (312) 695-1434 number. I anticipate the remainder should be available next week. Sincerely, -Al • Same e-mail sent to all three members of physician team
  • 61. AA09001711 – preliminary report – related references • 3/9/2009 2:44 PM 0 minutes E-mail Sent Subject: Correlagen Diagnostics: AA09001711: TNNT2 c.487 References Dear Dr. Bonow- As per request of Edith Pacheco, please find enclosed references for your review. The reference sheet has dynamic hyperlinks to the respective PUBMED publications for your access. Please feel free to contact me with any additional questions or requests. Sincerely, -Al
  • 63. AA09001711 – related references - comments • Acrobat document which has list of references which have direct access to Hyperlinked PUBMED references per variant found • Provides a higher lever of understanding for physicians to instantly research publically available literature • Document is not specific to patient • Document is specific to references in literature only – no internal data (blinded or not blinded) is provided
  • 64. AA09001711 – preliminary report – Action-Reaction • 3/9/2009 1:14 PM 10 minutes Call Received AA09001711 - family testing • Call received from Edith Pacheco • indicated mother of patient has deceased from possible HCM - however unsure • needs to know if perform testing on deceased human tissue or blood • will provide blood from deceased • Salesperson will provide special family pricing to all members • Edith to make several photocopies of requisition forms for family distribution.
  • 65. AA09001711 – family testing logistics • 3/16/2009 4:02 PM 5 minutes Call Received AA09001711 - family testing • Call received from Lake County Coroner's Office Deputy officer name • 847-377-2200 • mentioned had whole blood - frozen blood - collected in plastic vial - sodium fluoride as preservative – • prevent clotting • has multiple DNA standard cards • would be able to provide some blood
  • 66. AA09001711 – family sample reception • 3/18/2009 2:50 PM 0 minutes E-mail Sent Subject: Correlagen Diagnostics: partial patient name Dear Dr. Bonow- Thank you for choosing Correlagen Diagnostics as your genetics laboratory service provider. This e mail is confirmation that we have received your specimen(s) dated 3/18/09, and we are in the process of reviewing the documentation and specimen as instructed. We will contact you immediately in the event we are missing any required documentation or if the sample provided is not adequate for testing. The corresponding accession number given to your blood sample is AA09001829. Please feel free to call our Client Services Manager, Al Gunduz, at 781-647-0604 x261 with any additional information you may need or questions you might have.
  • 67. AA09001711 – report inquiry • 3/26/2009 12:22 PM 0 minutes E-mail Attachment Subject: Accession #: AA09001711 • Hi Al We received a fax copy of the genetic report for accession # AA09001711. Dr. Bonow would like to know if this result really is the result of the patient's deceased mother or more results for the patient himself? Thanks AD Angelene Delk Administrative Assistant to Robert Bonow, MD Bluhm Cardiovascular Institute of Northwestern
  • 68. AA09001711 – report inquiry - response • 3/26/2009 12:33 PM 0 minutes E-mail Sent Subject: Accession #: AA09001711 • Good Morning Angelene- The patient report that arrived yesterday is the final report to patient partial patient name. The initial report sent on March 9th, 2009 was the preliminary report sent by the Medical Director due to the significance of the variant found. The sample of the patient’s mother is accession #AA09001829. Please feel free to contact me if you have any additional questions. Sincerely, -Al Al Gunduz | Manager, Immunology and Client Services | Correlagen Diagnostics, Inc. | 781-647-0604 x261
  • 69. AA09001829 – logistics background • Patient AA09001829 is deceased and does not have effective insurance coverage • Issue of sample testing payment is in question • Initially determine from insurance of deceased that if coverage possible • Learned coverage termed at date of death
  • 70. AA09001829 – payment inquiry • 4/13/2009 1:04 PM 10 minutes Call Received • AA09001829 - payment issue • Received call from son of patient (AA09001711)indicated no coverage for patient • offered $100.00 deal • provided M/C XXXX 2973 exp
  • 71. AA09001829 – family testing • 4/28/2009 9:19 AM 10 minutes • AA09001829 - family testing • Call received from patient name given • sister of AA09001829 • left VM • provided phone 847-212-5166
  • 72. AA09001829 – family testing – further inquiry • 4/28/2009 9:56 AM 15 minutes • Call Received AA09001829 - family testing • Call received from patient full name given • sister of AA09001828 • DOB date given • BC/BS NY • ID EQP80090655 • Group 294572A11 • # 800-582-4489 • PO Box 5009, Middletown, Ny • Husband name with different surname given
  • 73. AA09001829 – testing logistics • Call received from Nurse Edith • Indicated wanted to simplify paperwork • Indicated to Edith will provide specialized paperwork specific to this family’s variant only. • Sent 3 Specimen Kits with specialized paperwork
  • 74. AA09001829 – family testing – other sister • 4/28/2009 12:48 PM 15 minutes Call Received AA09001892 - family testing • Call received from patient ‘s sister • 314-469-5922 • not aware of results for AA09001892 - DOE 1/31/2009 • provided address • Patient name given 13215 Hawkshead Court St. Louis, MO 63131 • DOB date given • UHC • ID: 903631475 • Group: 714084 Subscriber: patient • # 877-842-3210 • Providers Address: SLC, UT
  • 75. AA09001829 – family testing e-mail • 4/28/2009 5:28 PM 0 minutes E-mail Sent Subject: Correlagen Diagnostics: AA09001829 - family testing • Hello Edith- The first two family members have contacted me about family testing. You should received the package I sent tomorrow (if not today) with the special forms specific to this family. I have provided insurance coverage information to you for the first family member scheduled to visit your office next week. If you could please attach the following forms with her paperwork, this will make the process smoother. Please feel free to contact me if you have any additional questions or requests. Sincerely, -All
  • 76. AA09001966 family testing – – receipt e-mail • 5/12/2009 2:55 PM 0 minutes E-mail Sent Subject: Correlagen Diagnostics: Jan R. sample received Dear Ms. Pacheco- • Thank you for choosing Correlagen Diagnostics as your genetics • laboratory service provider. • This e mail is confirmation that we have received your specimen(s) dated • 5/12/2009, and we are in the process of reviewing the documentation and • specimen as instructed. We will contact you immediately in the event we • are missing any required documentation or if the sample provided is not • adequate for testing. The corresponding accession number given to your • blood sample is AA09001966. • Please feel free to call our Client Services Manager, Al Gunduz, at • 781-647-0604 x261 with any additional information you may need or • questions you might have.
  • 77. AA09001829 – family testing • 4/28/2009 12:48 PM 15 minutes Call Received AA09001892 - family testing • Call received from patient other sister • Home phone number • not aware of results for AA09001892 - DOE 1/31/2009 • provided address • provided insurance information • Indicated will be going to physician not in Chicago area
  • 78. AA09001829 – family testing • 4/29/2009 3:22 PM 10 minutes Call Completed • AA09001829 - request to share information • Spoke to Angie Delk (coordinator of Chicago physician) • indicated okay to share results with patient • will send e-mail confirming this.
  • 79. AA09001829 – family testing • 4/29/2009 3:28 PM 10 minutes Call Completed AA09001829 - family test • Spoke to receptionist Laurie • indicated nurse to contact me • fax send to 314-996-3268 • ATTN: Dr. Mankowitz - nurse Gerri / Lisa
  • 80. AA09001829 – family testing • 4/30/2009 9:53 AM 10 minutes Call Received AA09001829 - family testing • Call received with Gerri • gburke@im.wustl.edui • ndicated to send list of references • indicated that patient has specimen kit & pre- paid mailer • provided contact information • send list of references to Dr. Mankowitz and Gerri Burke
  • 81. AA09001829 – family testing • 4/30/2009 10:10 AM 0 minutes E-mail Attachment Subject: Correlagen Diagnostics: AA09001829 / AA09001711 - related references • Good Morning Gerri- • It was excellent speaking with you this morning about your patient Second sister . Please find attached references in regards to this variant. • The references are interactive in that they automatically link to the • corresponding PUBMED webpage to review each publication independently. • Please feel free to contact me with any additional questions or requests • on this matter. • Sincerely, • -Al
  • 82. AA09001829 – family testing • 4/30/2009 3:40 PM 0 minutes E-mail Attachment Subject: Correlagen Diagnostics: AA09001829 / AA09001711 - related references Thanks • The sister, my patient will be coming in for a gene study. • I would like to test her for the same gene. • Can you please send us the paperwork and tell us how much it will cost the patient Sample received on 5/8/2009 for second sister
  • 83. AA09001963 – family testing • 5/12/2009 10:30 AM 10 minutes Call Completed AA09001963 - family testing - 314-469-5922 • Spoke to patient • not to be billed to insurance • VISA XXXX 6812 exp 07/11 • final $100.00
  • 84. Limited Family Pedigree AA09001966 AA09001963 AA09001829 AA09001711 (index)
  • 86. Grand Timeline - Full Information
  • 87. Correspondence Count • Number of Correspondences (phone, e- mail, fax) with each particular accession – AA09001711 (index): 97 – AA09001829: 158 – AA09001963: 11+ – AA09001963: 18+ • Total as of 5/21/2009 for this family: 284