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Incretin Based Therapy of Type 2 Diabetes Mellitus BY Prof. ADEL A EL-SAYED MD Prof. of Internal Medicine Sohag Faculty of Medicine SOHAG EGYPT
Pathophysiology of Type 2 Diabetes  ,[object Object],[object Object]
Pathophysiology of Type 2 Diabetes Insulin Resistance ,[object Object],[object Object]
Pathophysiology of Type 2 Diabetes   Beta cell defect ,[object Object],[object Object],[object Object]
Pathophysiology of Type 2 Diabetes   Beta cell defect ,[object Object],[object Object],[object Object]
Pathophysiology of Type 2 Diabetes   Beta cell defect ,[object Object],[object Object]
Pathophysiology of Type 2 Diabetes   Other Factors ,[object Object],[object Object]
Pathophysiology of Type 2 Diabetes   Other Factors ,[object Object],[object Object],[object Object]
Pathophysiology of Type 2 Diabetes   The Glucagon Factor ,[object Object],[object Object],[object Object]
Pathophysiology of Type 2 Diabetes   The Glucagon Factor ,[object Object],[object Object],[object Object],[object Object]
 
Pathophysiology of Type 2 Diabetes   The Gastric Emptying Factor ,[object Object],[object Object],[object Object]
Pathophysiology of Type 2 Diabetes   One last observation ,[object Object],[object Object],[object Object],[object Object]
What are incretins? ,[object Object],[object Object],[object Object]
What are incretins? Gastric Inhibitory Polypeptide (GIP)   ,[object Object]
What are incretins?   Glucagon-like peptide-1 (GLP-1)  ,[object Object],[object Object],[object Object]
Actions of GLP-1 ,[object Object],[object Object],[object Object],[object Object],[object Object]
Actions of GLP-1 ,[object Object],[object Object],[object Object],[object Object]
Actions of GLP-1 ,[object Object]
 
Actions of GLP-1   The Problem ,[object Object]
The solution ,[object Object],[object Object],[object Object]
Incretin mimetics Exenatide   ,[object Object],[object Object],[object Object],[object Object]
 
Incretin mimetics Exenatide ,[object Object],[object Object],[object Object]
 
Clinical Trials of Exenatide   ,[object Object],[object Object],[object Object]
 
Weight Loss With Exenatide   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Nausea With Exenatide   ,[object Object],[object Object]
Incretin mimetics   Recent Advances ,[object Object],[object Object]
Dipeptidyl Peptidase-IV Antagonists   ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Dipeptidyl Peptidase-IV Antagonists   Sitagliptin and Vildagliptin ,[object Object],[object Object],[object Object],[object Object]
Dipeptidyl Peptidase-IV Antagonists   Recent Advances ,[object Object],[object Object]
Summary ,[object Object],[object Object],[object Object],[object Object],[object Object]
Summary ,[object Object],[object Object],[object Object]
Summary ,[object Object],[object Object],[object Object],[object Object]
 
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