8. Dr. Gutmann8
Prevalence of Cleft Lip & Palate
Country Years Prevalence Author
Finland 1948-1975 1.74 Rintala, 1986
Israel 1974-1988 0.97 Tolarova, 1998
USA 1983-1990 1.30 Druschel, 1996
Japan 1948-1954 2.68 Vanderas, 1987
France 1974-1996 1.9 Stoll, 2000
China 1980-1989 1.2 Cooper, 2000
Nigeria 1976-1980 0.37 Iregbulem, 1982
14. Dr. Gutmann14
Frequency
Unilateral left to Unilateral right to
Bilateral
6:3:1
CL/P male to female 2:1
CP female to male 2:1
CL/P to CL 1.5-3:1
CL to CL/P to CP 21%to 46% to 33%
Majority of CL/Ps are isolated
Majority of CPs are syndromic )McCarthy(
15. Dr. Gutmann15
Predicted Occurrence, %
)McCarthy(
CL/P P
One sibling affected 4 2
One parent affected 4 6
One sibling and one parent affected 17 15
Two siblings affected 9 1
One sibling plus family history 4 7
16. Dr. Gutmann16
Examples of Cleft Palate
Cleft of Back Soft Palate
Cleft of Soft Palate
Cleft of Soft and Hard Palate
Cleft of Soft and Hard Palate and Cleft Lip