4. oM > F 7:1
Bacterial o40-50 million amoeba
Most common infections/year worldwide
M > F 3:1 oAge Extremes
Risk factor: oEndemic Areas most
• DM susceptible
• Cancer oCountry of origin or
• Liver Transplant Travel
• Pregnancy
• Steroids
• Cancer
• Endemic area travel
(short or long term)
5. o Peritonitis
To liver via portal circulation
o Direct Spread
o Biliary infections
o Hematogenous Seeding
o Bacteremia
o Sites: R lobe most common
o Blood supply
:
o Fecal-Oral transmission into GI Tract
To liver via portal circulation
o Can also spread to other extraintestinal sites
o Heart
o Brain
o Lungs
12. early
• Treated with drug and no clinical improvement occurs in 48 to 72 hour
• All large abscesses (especially those presenting as localised swellings or
bulges of right lower thorax)
• Superficial abscess
• Abscesses causing severe pain or having marked tenderness or edema
and abscess with mark elevation of the diafragma
immediate
• Impending perforation
• Cases with left lobe abscess
• Ruptuire into the pericardiac sac or peritoneal cavity