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pyogenic



trauma                        amebic




         TB              candida
oM > F 7:1
 Bacterial              o40-50 million amoeba
 Most common            infections/year worldwide
 M > F 3:1              oAge Extremes
 Risk factor:           oEndemic Areas most
    • DM                 susceptible
    • Cancer             oCountry of origin or
    • Liver Transplant   Travel
                         •   Pregnancy
                         •   Steroids
                         •   Cancer
                         •   Endemic area travel
                             (short or long term)
o Peritonitis
      To liver via portal circulation
 o Direct Spread
     o Biliary infections
 o Hematogenous Seeding
     o Bacteremia
o Sites: R lobe most common
     o Blood supply

              :
 o Fecal-Oral transmission into GI Tract
      To liver via portal circulation
 o Can also spread to other extraintestinal sites
     o Heart
     o Brain
     o Lungs
ANTIBIOTIC
• Pyogenic: Gram Neg + Anaerobe cov.
  • Penisilin
  • Combination :
  1. ampisilin+aminoglikoside
  • +sefalosprin 3th
  2. Sefalosporin 3th+klindamisin
  3. Metronidazol
  48-72 jam  perbaikan -  kultur
• Perenteral 10-14 hari, 6 minggu oral

• Amoeba: Metronidazol, tinidazol
   •   50 mg/kgBB  10 hari
early

• Treated with drug and no clinical improvement occurs in 48 to 72 hour
• All large abscesses (especially those presenting as localised swellings or
  bulges of right lower thorax)
• Superficial abscess
• Abscesses causing severe pain or having marked tenderness or edema
  and abscess with mark elevation of the diafragma

immediate

• Impending perforation
• Cases with left lobe abscess
• Ruptuire into the pericardiac sac or peritoneal cavity
Liver abcess
Liver abcess

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Liver abcess

  • 1.
  • 2. .
  • 3. pyogenic trauma amebic TB candida
  • 4. oM > F 7:1  Bacterial o40-50 million amoeba  Most common infections/year worldwide  M > F 3:1 oAge Extremes  Risk factor: oEndemic Areas most • DM susceptible • Cancer oCountry of origin or • Liver Transplant Travel • Pregnancy • Steroids • Cancer • Endemic area travel (short or long term)
  • 5. o Peritonitis  To liver via portal circulation o Direct Spread o Biliary infections o Hematogenous Seeding o Bacteremia o Sites: R lobe most common o Blood supply : o Fecal-Oral transmission into GI Tract  To liver via portal circulation o Can also spread to other extraintestinal sites o Heart o Brain o Lungs
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11. ANTIBIOTIC • Pyogenic: Gram Neg + Anaerobe cov. • Penisilin • Combination : 1. ampisilin+aminoglikoside • +sefalosprin 3th 2. Sefalosporin 3th+klindamisin 3. Metronidazol 48-72 jam  perbaikan -  kultur • Perenteral 10-14 hari, 6 minggu oral • Amoeba: Metronidazol, tinidazol • 50 mg/kgBB  10 hari
  • 12. early • Treated with drug and no clinical improvement occurs in 48 to 72 hour • All large abscesses (especially those presenting as localised swellings or bulges of right lower thorax) • Superficial abscess • Abscesses causing severe pain or having marked tenderness or edema and abscess with mark elevation of the diafragma immediate • Impending perforation • Cases with left lobe abscess • Ruptuire into the pericardiac sac or peritoneal cavity