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Classification of general anaesthetics and pharmacokinetics

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CLASSIFICATION OF GENERAL ANAESTHETICS
1.INHALATIONAL Gases: N 2 O,Cyclopropane,Xenon Liquids: Ether, Halothane, Enflurane, Desflurane, Isoflurane, Sevoflurane, Methoxyflurane
2.INTRAVENOUS Inducing Agents : Thiopentone sodium, Methohexitone sodium, Propofol, Etomidate Dissociative Anaesthesia: Ketamine Neuroleptanalgesia: Fentanyl+Droperidol (Analgesic)(Neuroleptic) BZDs: Diazepam,Lorazepam,Midazolam
Pharmacokinetics ,[object Object],[object Object],[object Object],[object Object]
Minimum Alveolar Concentration ,[object Object],Halothane 0.75% Ether 1.9% Enflurane 1.68% Isoflurane 1.2% Desflurane 6% Sevoflurane 2% Nitrous oxide 105%
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Minimum Alveolar Concentration limitations ,[object Object],[object Object],[object Object],[object Object],[object Object]
Factors affecting pp of anaesthetic in brain ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
1.PP of the anaesthetic in inspired air
PP of the anaesthetic in inspired air ,[object Object],[object Object]
Fick’s Law of Diffusion ,[object Object],[object Object]
2.PULMONARY VENTILATION
2.Pulmonary Ventilation Rate ,[object Object],[object Object],[object Object]
3.ALVEOLAR EXCHANGE
ALVEOLAR EXCHANGE ,[object Object],[object Object]
4.SOLUBILITY IN BLOOD
SOLUBILITY IN BLOOD ,[object Object],[object Object],[object Object]
5.SOLUBILITY IN TISSUES
SOLUBILITY IN TISSUES ,[object Object],[object Object],[object Object],[object Object]
6.CEREBRAL BLOOD FLOW
CEREBRAL BLOOD FLOW ,[object Object],[object Object],[object Object]
Second gas effect ,[object Object],[object Object]
Concentration effect ,[object Object]
e Elimination ,[object Object],[object Object],[object Object],[object Object]

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Classification of general anaesthetics and pharmacokinetics