These slides are from the April 2012 Bio-Link Summit in St. Louis, MO.

1. BIO-LINK SUMMIT
Bioscience Businesses/Education Models: Economic and Educational Impact
April 18-20, 2 012

2. WELCOME!

3. Panel 1: Bioscience Business/Education Models
MODERATOR: Eilene Lyons, Acting Dean MSET Division, STLCC-Florissant Valley
PANELISTS:
Adam Blaszczak, InnovaBio CRO, Salt Lake Community College
Vivian Ngan-Winward, STUDENTfacturED, Salt Lake Community College
R. Kevin Pegg, Florida State College at Jacksonville
Wendie Johnston, Pasadena City College
Suzanne Winters, BioInnovations Gateway, St. Lake City

4. Eilene Lyons
St. Louis Community College-Florissant Valley

5. BIO-LINK SUMMIT April 18-20, 2012
STLCC BioBench CRO
Community College/ Incubator Model
Eilene Lyons
Interim Dean, STEM Division STLCC-Florissant Valley
STLCC Biotechnology Program
Founding Coordinator

6. Pathway for Success
• Founded Fall 1999; R&D based
• 2+2+2 Pathway
• Bridge to STEM and Life Science CS
• AAS Biotechnology
• Post-baccalaureate certificate

7. Vision for Growth: Step 1
Battelle study, January 2005
“As the region’s start-up companies expand, there is likely to be
greater demand for technicians than can be produced
currently. An option that might be considered to enable STLCC
to expand their biotechnology offerings would be to provide
lab space for the college in the new multi-tenant building
being planned…”

8. Vision for Growth: Step 2
• NSF funded CRO within BRDG Park
• Primary Goal: Internships in research
• Secondary Goal: Build the industry and jobs
– Lab space
– High end equipment and instrumentation
– Lab assistants

9. Growth Realized
• Successful placement out of CRO
– 6 Monsanto/ Divergence
– 2 Phycal
– 1 Electrochaea
– 1 Danforth Plant Science Center
– 10 interns currently
– 1 engineering student
– 1 horticulture student

10. BIO-LINK SUMMIT April 18-20, 2012

11. Adam Blaszczak
InnovaBio, Salt Lake Community College

12. A new concept to partner with
businesses to provide service to one
partner
And educational credit to another within
the structure of the educational
institution.
Lessons learned:
It works.
Fine print (word of caution) don’t
try it at home. Well, try… but in
our opinion…
Not as easy at it sounds

13. Mission
• Our mission is to mentor the next generation of
Biotechnology Graduates and simultaneously assist
local scientific and biotech enterprises in
developing research projects.
• Recipe for success – key ingredient? True balance
Business
Students

14. The Model
Real Science, Real Lab, Real Scientists.
• Business side
– Blanket contract reviewed by legal departments (long process) covers
for 2-5 yrs.
– Scientific design for each project (short process) with proposed budget
– Clearly stated deliverable (including negative data)
– Set deadline for completion (give yourself extra time)
– Projects with the greatest corporate attention will likely not be
contracted to Innovabio – Backburner projects yes.
– Moderate priority projects with moderate to low investment
– Build a reputation.
– Establish trust – honesty about limitations.

15. Disadvantages of InnovaBio
• Confidentiality
– Cannot enforce confidentiality agreement (under 18)
• Innovabio’s limited area of expertise
– Cannot be specialists in all areas
– Availability of equipment for specialized protocols
• Not a quick process
– If you want it done now Innovabio is not for you
• Company needs to be involved in Innovabio for the
process to work

16. Advantages of InnovaBio
• Company owns the intellectual property
• Accomplish a moderate priority project without sacrificing existing personnel
allocations
– Company has only enough time for high priority projects
– Moderate priority projects are still important to bottom line
• Costs are equal to or less than performing the experiment in house
– Cheaper than hiring consultants
• Use of equipment and facilities for project completion
– Innovabio uses their own equipment and lab space
• Minimal corporate oversight
– Company provides goals and objectives
– Innovabio provides updates and all developed product information and/or
materials
– No need to provide direct supervision
• Availability of qualified labour pool

17. The Model
Real Science, Real Lab, Real Scientists.
• Student side
• Each student 30 minute interview – assessment of the skills (course 1010 and 1015 or
equivalent) and time commitment (at least 12 – 15 hours a week)
• Real Challenge: Realized that as our projects are real science things are unknown and hard
to control so we are unable to tell whether the project is hard and needs some
troubleshooting or the students is messing up. Real Solution: Training Packet – Great Tool for
us. A set of experiments designed to give certain results when done right, plus some other
lab training. This allows us to asses whether a student is truly ready to be assigned to a real
project. We reserve the right to let students know during this period that they need to take
more classes. Very often during this time students themselves decide that this is way over
their heads and decide to take more classes and then return. Current Innovation: Short
training movies embedded into Training Packet. Interactive Training Packet as an APP on
iPads.
• Students assigned to real projects contracted by companies to InnovaBio.
• Project Leaders – Leadership Academy. Real Challenge: how to ensure skill consistency on
projects. Real Solution: Select group of students after completion stick around – we offer
them opportunities for growth – they lead and help train students for specific projects.
Current Innovation: “Training Packet on Steroids”

18. Adam Blaszczak Mary Nelson Alejandro Pabon
Director, InnovaBio Assistant Director, Research Associate,
>20 years research InnovaBio InnovaBio
experience > 10 years research > 7 years of research
experience experience
Director – Team leader. Scientific design, oversight and management of all
the projects. Business relations and negotiations with clients. Marketing,
billing and accounting. Public Relations.
Assistant Director – day-to-day student oversight, evaluations and
supervision. Daily project coordination and scientific resource. Recruitment.
Research Associate – Project troubleshooting. Scientific resource. Report
writing.

19. InnovaBio in a business of
“Talent creation, not discovery”
Genius? Or just Smart…enough
People used to believe in “natural” talents
• Step1. Separate • What really matters:
“talented” from the – Who gets the best teaching
and most attention
“untalented”
– Who gets the most coaching
• Step2.Provide the and practice
“talented” with a – Who gets all the
extraordinary opportunities
superior experience

21. Vivian Ngan-Winward
STUDENTfracturED, Salt Lake City Community College

22. Vivian Ngan-Winward
Director, Biomanufacturing Program
Biotechnology Department
This material is based upon work
supported by the National Science
Foundation under Grant No. 1003292.

23. What’s unique ?
• Contract manufacturing organization
• A complete business enterprise:
 Biotechnology / biomanufacturing
 Accounting
 Business Management
 Marketing
• A regulated yet learning-centered
environment
Comprehensive entrepreneurial experience

24. Sustainability Potential
• Products: instructional supplies
 Biotechnology, & Biology, Chemistry, Health Sci ?
 Custom
 Equipment ?
• Customers: educators
 SLCC & local high schools
 ???
• Income $$$: reinvest into CMO for
 Mentor / staff support
 New product development

25. Outcomes
• Forced application of knowledge and
skills
• Mistakes → lessons learned
• Integrated and deep learning –
Bloom’s Analyzing/Evaluating/Creating levels
• On-the-job training, before the job
• Transformative mentoring
• Interns want additional training

26. Student Testimonials
“ . . .I have learned again the importance of
communication, mutual support . . .”
“. . . This experience has made me more excited
and confident to work for a company . . .”
“. . .The best part about STUDENTfacturED is
that I got real world knowledge and I did not
have to spend hundreds of dollars on a new
text book . . .”

27. Student Testimonials
“. . . One the most important lessons I can
take from this experience is how to work in
teams . . .”
“. . . All the skills I have learned will definitely
help build my resume . . .”
“STUDENTfacturED provides great exposure
to working in a regulated industry. This
type of experience is unrivaled in any
classroom I've ever seen.”

28. R. Kevin Pegg
Florida State College at Jacksonville

29. The Co-located CRO Model:
R. Kevin Pegg, Florida State College at Jacksonville
Panel 1: Bioscience Business/Education Models 8:45am – 10:00am
The FSCJ Biotechnology program
is an A.S. laboratory technician training
with two tracks:
an academic track that trains for
Mayo Clinic, UF Shands;
and a food safety testing track.
The facility incorporates a “third-party”
International testing company fully
integrated into the program:
Physically, financially, an academically.

30. • Eurofins Partnership:
– Eurofins companies have about US $800 million annual sales and 7,000 employees
across 150 sites in 29 countries
• FSCJ is their only site in Florida
• Portfolio of over 40,000 analytical methods, familiar brands such as MWG Operon
• Eurofins operates under a Memorandum of Understanding (MOU) with the
college
– Request for Information December 2008
• Request for Proposal April 2009
– Negotiations throughout 2010
» Operations proceeded starting Summer 2010
– Launched officially in October 2010
• First cohort of students in 2010/2011
• Eurofins pays rent based on local averages
– Utilities are flat-rate
– Returns share of profits based on modified “Lehman formula” (1M:2M:3M:4M:5M)
– Agreements on IP, confidentiality, no exclusivity
– Require TPO to intern and provide traineeships—
• But not agreement to hire students preferentially
Third Party Operator Model

31. Separate, Shared, and “mirrored” spaces
Current crop of students
observing Eurofins
operations
via view ports
Interns and
trainees
Graduate, now full time
Physically Integrated

32. • Eurofins participates directly in program
goals:
– Curriculum reviews
– SOP development
– Advising students interested in the field
– Advisory Boards
• College participates in industry directions
– Standards development
– Technical meetings
– Best practices, materials
Academically Integrated

33. • “Access”
– Steady stream of people--scientists and Intangibles
corporate– one would never encounter in a
purely academic environment
• Trends
– Eurofins called the FSMA legislation two years
before it was passed (hint: they wrote it)
• Vendor credibility
– Ultra LC-MS
*

34. Wendie Johnston
Pasadena City College

35. Shared use wetlab BCN Biosciences
Month to month rent:
Bench, desk, shelves
Fully equipped lab
Tissue culture facility
Not for profit

36. ORIGINAL FUNDING: 2004:
STATE LEGISLATION - 500 sq ft in shared
FOUNDING MEMBERS: use facility
City, Industry, SoCalBio, - 2 tenants
Community College, - Donated desks,
State University, Caltech casework, equipment

37. DetonCorp
2012: Jobs Created
- 10,000+ sq ft Current tenants: 78
- 16+ tenants Graduates: 55
- 6 successful graduates 2 spin-offs

38. Benefit to Tenant
100% ownership of IP
Discounted supplies - BIO
Collaboration - other tenants
High speed internet
Basic office equipment
Interns available
Resource list Ophidion
Trade Organization membership

39. Collaborations
Industry and university donations
Amgen Bruce Wallace Lab Program
Saturday mentored workdays for high
school and college students -
internship preparation

40. Suzanne Winters
BioInnovations Gateway, Salt Lake City

41. BioInnovations Gateway
Growing Talent… Growing Business
Governor Herbert’s Agenda:
 Strengthen and grow Utah businesses
 Increase innovation, entrepreneurship and investment
 Increase national and international business
 Prioritize education to develop the workforce of the future
GOALS
To provide life science start-up businesses a competitive edge by providing access to state-of-
the-art space, equipment and talent in a cost-effective manner
To provide a workforce training program offering real-life, hands on experience in which
students develop creative thinking and life science work skills in a product-driven environment

42. BioInnovations Gateway
Growing Talent… Growing Business
Incubator Companies Biomanufacturing /Biotechnology/Engineering
 7 Company Labs  Industry driven curricula
 Biotech & Medical Device  Concurrent enrollment with SLC
 Quarterly milestone evaluation  Internships strongly encouraged
 CEO Lunch and Learn
Facilities BiG
 Classrooms
 Teaching Labs
 Company Labs Students
 Shared Wet/Analytical Labs
BioIn BioMan
 CAD Lab
 Machine Shop/Prototyping Lab

43. BioInnovations Gateway
Growing Talent… Growing Business
Workforce Training Component-
3 Tier Learning Model
1. Basic labs (yr 1)-- Research equipment (yr 2)
2. BioInnovateTM – Student Design/Development Projects
Contract Manufacturing and Distribution
2b. Intern-in-Training
3. Resident company internships

44. BioInnovations Gateway
Growing Talent… Growing Business
Life Science Business Incubator Component
 Companies must be committed to the workforce training
component of the facility
 Companies required to conduct seminars for students/classes
 Companies strongly encouraged to hire student interns
 (min 8 wks)
 If equipment scheduling conflicts occur, classes take priority

45. BioInnovations Gateway
Growing Talent… Growing Business
Benefits to Students/Teachers
 Internships/experiential learning
BiG  Advanced skills
 Improved employability
 Professional development
Students  Networking w/ entrepreneurs
 Networking w/ chief scientists
CRO BioMan Benefits to Companies
 Access to high-end equipment
Benefits to Utah  Availability to interns
 New companies and jobs  Grooming of potential employees
 Trained workforce pipeline  Affordable office/laboratory
 Serve as a national model space
 Contract research capabilities

46. BioInnovations Gateway
Growing Talent… Growing Business
Incubator Metrics
 Currently 5 client companies- 28 new jobs created
 5 patent filings, 2 license agreements, 4- 510(k) submissions and 2
scientific publications
 Ongoing monthly CEO seminars/training
 Quarterly technical and business milestones reviews with each client
 More than $11.5 Million investment capital secured
 First graduation June 2012!

47. BioInnovations Gateway
Growing Talent… Growing Business
Workforce Metrics
 155 high school students
 1000 9th graders (pipeline)
 Biomanufacturing curriculum revisions
 Injection Molding certification program
 Ongoing student seminar series and industry field trips
 Senior project credit for BioInnovate/Internships
 Intern-in-Training program for students
 Completed BioInnovate project (Patent issued and interested
licensee)

48. BioInnovations Gateway
Growing Talent… Growing Business
Thank You!
Suzanne Winters, Ph.D.
Director, BioInnovations Gateway
2500 South State Street
South Salt Lake, UT 84115
phone: 385.646.4625
fax: 385.646.4381
suzannewinters@utah.gov
www.bioinnovationsgateway.org

49. Panel 2: Challenges in setting up Business/Education
Models
MODERATOR: Dr. Kathryn Birmingham, Dean, Florida State College at Jacksonville
PANELISTS:
Elizabeth Boedeker, St. Louis Community College
Linnea Fletcher, Austin Community College
Tami Goetz, Former Biotechnology Program Chair, Salt Lake Community College
Chuck Crabtree, Director - Iowa BioDevelopment, Indian Hills Community College

50. Panel 3: Educational & Workforce Development Impacts
of Business/Education Models
MODERATOR: Laurence Clement, Synergy-B2B Project Leader, Bio-Link
PANELISTS:
Candiya Mann (by Skype), Senior Research Manager at Washington State University
Peggy Weeks, BioBench Evaluator, St. Louis Community College
Alicia Manfre, Hagerstown Community College
Ian Rappold, student in St. Louis CC Program
Adam Blaszczak, Salt Lake Community College

51. Panel 4: Economic/Business Impacts of
Business/Education Models
MODERATOR: John Carrese, Centers of Excellence/Bio-Link,City college of San Francisco
PANELISTS:
Beth Noonan, St. Louis County Economic Council
Marc Vanacht, Trophomax, St. Louis
Tim Nieman, CEO, Zien Medical, BioInnovations Gateway, Salt Lake City
Tami Goetz, Governor’s Office of Economic Development, Salt Lake City

52. Open Mic Topic: Quality Assurance for National
CRO/CMO Programs
Craig Caldwell (by Skype), Biotechnology Department Chair, Salt Lake
Community

53. THANK YOU!