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Università	
  di	
  Padova	
  

Founded	
  in	
  1222	
  
More	
  than	
  65.000	
  students	
  
More	
  than	
  2.400	
  researchers	
  
Strong	
  engineering,	
  agricultural,medical	
  and	
  law	
  
schools	
  
Budget	
  >	
  600	
  Mln	
  Euro	
  




                                                               2
Tech	
  Transfer	
  Offices	
  in	
  Italy	
  

TT	
  offices	
  have	
  been	
  opened	
  only	
  recently	
  


Only	
  5	
  TT	
  offices	
  opened	
  before	
  the	
  year	
  2000,	
  58	
  
in	
  the	
  year	
  2008	
  




                                                                                 3
Yearly	
  budget	
  of	
  Universi<es	
  with	
  TTO	
  
Budget	
  of	
  the	
  top	
  5	
  UniversiJes	
  on	
  average	
  	
  ~	
  650	
  Mln	
  
Euro	
  
Average	
  on	
  all	
  UniversiJes	
  ~	
  210	
  Mln	
  Euro	
  

Approximately	
   26%	
   of	
   the	
   funding	
   comes	
   from	
   the	
  
government	
  
Another	
  26%	
  from	
  research	
  contracts	
  
12%	
  comes	
  from	
  the	
  European	
  Union	
  
12%	
  from	
  local	
  regional	
  government	
  	
  
14%	
  from	
  the	
  universiJes	
  own	
  resources	
  
the	
   remaining	
   10%	
   from	
   different	
   sources,	
   bank      	
  
foundaJons,	
  etc.	
  

                                                                                             4
TTO activities	
  

The	
  TT	
  offices	
  declare	
  the	
  following	
  main	
  
ac<vi<es:	
  

Support	
  to	
  creaJon	
  and	
  to	
  the	
  development	
  
of	
  spinout	
  companies	
  

IP	
  management	
  

Research	
  contracts	
  with	
  companies	
  

Management	
  of	
  conflicts	
  of	
  interest	
  



                                                                  5
Support	
  to	
  spinout	
  companies	
  

Business	
  Plan	
  compeJJons,	
  seminars	
  on	
  business	
  
plan	
  wriJng,	
  entrepreneurship	
  

Beneficial	
  condiJons	
  on	
  IP	
  licensing	
  to	
  spinout	
  
companies	
  

Lab	
  space,	
  instruments	
  

Company	
  incubators	
  

The	
  University	
  may	
  become	
  a	
  minority	
  shareholder	
  

                                                                         6
The	
  spinout	
  scenario	
  

How	
  many,	
  where,	
  sectors:	
  
In	
  2008	
  the	
  overall	
  number	
  of	
  university	
  spinout	
  
companies	
  was	
  higher	
  than	
  800	
  
The	
  average	
  revenues	
  are	
  about	
  500	
  K	
  Euro	
  per	
  year	
  
The	
  creaJon	
  rate	
  was	
  higher	
  than	
  100/per	
  year	
  since	
  	
  
2006	
  
Spinouts	
  are	
  based	
  mostly	
  in	
  northern	
  and	
  central	
  Italy,	
  
but	
  also	
  in	
  some	
  regions	
  of	
  the	
  south	
  like	
  Puglia	
  
The	
  three	
  main	
  sectors	
  are:	
  ICT	
  33%,	
  Energy	
  cleantech	
  
16%,	
  Life	
  sciences	
  15%	
  	
  

                                                                                       7
Spinout	
  and	
  venture	
  

According	
  to	
  AIFI,	
  the	
  Venture	
  Capital	
  and	
  Business	
  
Angel	
  Associa<on	
  in	
  Italy,	
  	
  the	
  total	
  seed	
  investment	
  in	
  
Italy	
  is	
  lower	
  than	
  40	
  Mln	
  Euro	
  per	
  year	
  
The	
  investments	
  are	
  mostly	
  in	
  companies	
  that	
  are	
  NOT	
  
university	
  spinout	
  




                                                                                          8
Spinout	
  and	
  venture	
  


Most	
  spinout	
  companies	
  are	
  not	
  fit	
  for	
  investments	
  
by	
  venture	
  capitals	
  
Some	
  direct	
  examples	
  of	
  two	
  spinout	
  companies	
  that	
  
I	
  personally	
  founded	
  before	
  M31:	
  
eMoJon	
  Srl,	
  first	
  official	
  spinout	
  company	
  of	
  the	
  
University	
  of	
  Padova;	
  
VI-­‐grade	
  GMBH.	
  




                                                                              9
eMo<on	
  Srl	
  

Founded	
  in	
  the	
  year	
  2000	
  with	
  an	
  investment	
  of	
  300	
  K	
  Euro	
  
from	
  a	
  business	
  angel	
  and	
  a	
  private	
  company	
  




  It	
  offers	
  moJon	
  capture	
  systems	
  for	
  clinical	
  applicaJons	
  
  Based	
  on	
  research	
  on	
  tracking	
  and	
  data	
  associaJon	
  

                                                                                             10
eMo<on	
  Srl	
  

Sold	
  in	
  2002	
  to	
  a	
  public	
  company	
  and	
  merged	
  into	
  BTS	
  Spa	
  
www.bts.it	
  




  Today	
  it	
  counts	
  28	
  employees	
  and	
  it	
  has	
  revenues	
  for	
  about	
  
  5	
  Mln	
  Euro	
  	
  

                                                                                                11
VI-­‐grade	
  GMBH	
  
Founded	
  with	
  a	
  manager	
  who	
  had	
  an	
  important	
  sale	
  
experience	
  in	
  the	
  area	
  




 It	
  offers	
  CAE	
  tools	
  for	
  the	
  automoJve,	
  train	
  and	
  aerospace	
  
 industry	
  
 Based	
  on	
  research	
  on	
  the	
  control	
  of	
  mechanical	
  systems	
  
                                                                                        12
VI-­‐grade	
  GMBH	
  

VI-­‐grade	
  counts	
  25	
  employees	
  and	
  it	
  has	
  revenues	
  for	
  2.5	
  
Mln	
  Euro	
  




  It	
  is	
  owned	
  by	
  the	
  managers	
  who	
  joined	
  the	
  company	
  one	
  
  year	
  acer	
  its	
  incorporaJon	
  


                                                                                            13
IP	
  issues	
  


In	
  both	
  eMoJon	
  and	
  VI-­‐grade	
  cases	
  the	
  support	
  by	
  the	
  TTO	
  
on	
  the	
  possibility	
  of	
  protecJng	
  the	
  products	
  with	
  patents	
  
was	
  non	
  existent.	
  There	
  was	
  no	
  “procedure”	
  

The	
  Italian	
  law	
  assigns	
  the	
  ownership	
  of	
  the	
  invenJon	
  and	
  
the	
  rights	
  to	
  the	
  inventor,	
  not	
  to	
  the	
  University	
  

Most	
  TTO	
  do	
  not	
  have	
  budget	
  to	
  cover	
  the	
  costs	
  for	
  the	
  
deposit	
  of	
  the	
  patent	
  applicaJon	
  	
  




                                                                                              14
The	
  IP	
  scenario	
  

The	
  “top	
  5”	
  universiJes	
  count	
  at	
  the	
  end	
  of	
  2008	
  a	
  
porfolio	
  of	
  about	
  200	
  patents	
  each	
  

The	
  average	
  of	
  all	
  the	
  universiJes	
  that	
  have	
  a	
  TTO	
  is	
  of	
  
about	
  40	
  patents	
  each	
  

The	
  investment	
  in	
  IP	
  is,	
  on	
  the	
  average,	
  of	
  about	
  220	
  
thousand	
  Euro	
  per	
  year	
  for	
  the	
  “top	
  5”	
  and	
  of	
  somewhat	
  
more	
  than	
  50	
  thousand	
  Euro	
  for	
  all	
  the	
  universiJes	
  with	
  a	
  
TTO	
  

On	
  the	
  average	
  the	
  “top	
  5”	
  close	
  5	
  to	
  7	
  licensing	
  deals	
  per	
  
year	
  and	
  all	
  the	
  universiJes	
  1	
  



                                                                                                      15
The	
  IP	
  scenario	
  



The	
  revenues	
  generated	
  by	
  the	
  licensing	
  deals	
  for	
  the	
  “top	
  
5”	
  universiJes	
  is	
  about	
  150	
  thousand	
  Euro	
  per	
  year	
  on	
  
average	
  

Netval,	
  an	
  associaJon	
  of	
  46	
  TTO	
  in	
  Italy	
  recently	
  assigned	
  
to	
  a	
  private	
  company	
  the	
  commercializaJon	
  of	
  their	
  IP	
  




                                                                                            16
The	
  minuses	
  of	
  the	
  Italian	
  scenario	
  
Doctoral	
  schools	
  	
  
• 	
  There	
  are	
  few	
  students	
  
• 	
  The	
  basin	
  of	
  airacJon	
  is	
  local,	
  few	
  internaJonal	
  
students	
  
• 	
  Entrepreneurship	
  is	
  weak	
  amongst	
  the	
  PhD	
  students	
  	
  
• 	
  The	
  recruiJng	
  process	
  is	
  defecJve	
  
The	
  innova<on	
  ecosystem	
  
• 	
  There	
  is	
  a	
  limited	
  M&A	
  acJvity	
  on	
  high	
  technology	
  
companies	
  
• 	
  The	
  intangibles	
  are	
  ocen	
  not	
  considered	
  in	
  the	
  
evaluaJon	
  of	
  a	
  company	
  
• 	
  There	
  is	
  no	
  altude	
  to	
  design	
  companies	
  that	
  work	
  in	
  
the	
  early	
  stages	
  of	
  the	
  supply	
  chain	
  offering	
  IP	
  

                                                                                           17
The	
  pluses	
  of	
  the	
  Italian	
  scenario	
  

Opportuni<es	
  
• 	
  There	
  are	
  numerous	
  pockets	
  of	
  excellency	
  in	
  research	
  
Italy	
  is	
  the	
  third	
  country	
  in	
  the	
  world	
  for	
  number	
  of	
  
scienJfic	
  publicaJons	
  
• 	
  Engineers	
  are	
  prepared,	
  skilled,	
  loyal	
  and	
  do	
  not	
  cost	
  
astronomically	
  
• 	
  Funds	
  are	
  becoming	
  available,	
  see	
  for	
  example	
  the	
  
Fondo	
  Italiano	
  di	
  InvesJmento	
  
• 	
  The	
  UE	
  is	
  pushing	
  on	
  the	
  local	
  regional	
  governments	
  
to	
  support	
  the	
  creaJon	
  of	
  new	
  ventures	
  
• 	
  The	
  quality	
  of	
  life	
  is	
  high	
  and	
  can	
  airact	
  skilled	
  
managers	
  and	
  researchers	
  from	
  abroad	
  


                                                                                           18
The	
  needs	
  of	
  the	
  Italian	
  scenario	
  

Doctoral	
  schools	
  and	
  research	
  
• 	
  InternazionalizaJon	
  
• 	
  Stronger	
  and	
  focused	
  public	
  investments	
  on	
  doctoral	
  
programs	
  
• 	
  Support	
  for	
  hiring	
  few	
  qualified	
  research	
  managers,	
  
world	
  famous	
  scienJsts	
  capable	
  of	
  managing	
  large	
  labs	
  

The	
  innova<on	
  eco	
  system	
  
• 	
  Build	
  the	
  innovaJon	
  supply	
  chain	
  starJng	
  from	
  
companies	
  accellerators	
  linked	
  to	
  early	
  stage	
  venture	
  
capitals	
  
• 	
  Focus	
  on	
  the	
  global	
  market	
  for	
  the	
  M&A	
  acJvity	
  


                                                                                   19
What	
  does	
  M31	
  do?	
  

M31	
  Italia	
  turns	
  innovaJve	
  technologies	
  into	
  start-­‐
ups.	
  
M31	
  USA	
  turns	
  technology	
  start-­‐ups	
  into	
  successful	
  
global	
  companies.	
  
M31	
  was	
  incubated	
  in	
  Startcube	
  the	
  University	
  of	
  
Padova	
  start	
  up	
  accellerator	
  




                                                                            20

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Ruggero Frezza - Uni Padova - M31 - Stanford - Feb 14 2011

  • 1.
  • 2. Università  di  Padova   Founded  in  1222   More  than  65.000  students   More  than  2.400  researchers   Strong  engineering,  agricultural,medical  and  law   schools   Budget  >  600  Mln  Euro   2
  • 3. Tech  Transfer  Offices  in  Italy   TT  offices  have  been  opened  only  recently   Only  5  TT  offices  opened  before  the  year  2000,  58   in  the  year  2008   3
  • 4. Yearly  budget  of  Universi<es  with  TTO   Budget  of  the  top  5  UniversiJes  on  average    ~  650  Mln   Euro   Average  on  all  UniversiJes  ~  210  Mln  Euro   Approximately   26%   of   the   funding   comes   from   the   government   Another  26%  from  research  contracts   12%  comes  from  the  European  Union   12%  from  local  regional  government     14%  from  the  universiJes  own  resources   the   remaining   10%   from   different   sources,   bank   foundaJons,  etc.   4
  • 5. TTO activities   The  TT  offices  declare  the  following  main   ac<vi<es:   Support  to  creaJon  and  to  the  development   of  spinout  companies   IP  management   Research  contracts  with  companies   Management  of  conflicts  of  interest   5
  • 6. Support  to  spinout  companies   Business  Plan  compeJJons,  seminars  on  business   plan  wriJng,  entrepreneurship   Beneficial  condiJons  on  IP  licensing  to  spinout   companies   Lab  space,  instruments   Company  incubators   The  University  may  become  a  minority  shareholder   6
  • 7. The  spinout  scenario   How  many,  where,  sectors:   In  2008  the  overall  number  of  university  spinout   companies  was  higher  than  800   The  average  revenues  are  about  500  K  Euro  per  year   The  creaJon  rate  was  higher  than  100/per  year  since     2006   Spinouts  are  based  mostly  in  northern  and  central  Italy,   but  also  in  some  regions  of  the  south  like  Puglia   The  three  main  sectors  are:  ICT  33%,  Energy  cleantech   16%,  Life  sciences  15%     7
  • 8. Spinout  and  venture   According  to  AIFI,  the  Venture  Capital  and  Business   Angel  Associa<on  in  Italy,    the  total  seed  investment  in   Italy  is  lower  than  40  Mln  Euro  per  year   The  investments  are  mostly  in  companies  that  are  NOT   university  spinout   8
  • 9. Spinout  and  venture   Most  spinout  companies  are  not  fit  for  investments   by  venture  capitals   Some  direct  examples  of  two  spinout  companies  that   I  personally  founded  before  M31:   eMoJon  Srl,  first  official  spinout  company  of  the   University  of  Padova;   VI-­‐grade  GMBH.   9
  • 10. eMo<on  Srl   Founded  in  the  year  2000  with  an  investment  of  300  K  Euro   from  a  business  angel  and  a  private  company   It  offers  moJon  capture  systems  for  clinical  applicaJons   Based  on  research  on  tracking  and  data  associaJon   10
  • 11. eMo<on  Srl   Sold  in  2002  to  a  public  company  and  merged  into  BTS  Spa   www.bts.it   Today  it  counts  28  employees  and  it  has  revenues  for  about   5  Mln  Euro     11
  • 12. VI-­‐grade  GMBH   Founded  with  a  manager  who  had  an  important  sale   experience  in  the  area   It  offers  CAE  tools  for  the  automoJve,  train  and  aerospace   industry   Based  on  research  on  the  control  of  mechanical  systems   12
  • 13. VI-­‐grade  GMBH   VI-­‐grade  counts  25  employees  and  it  has  revenues  for  2.5   Mln  Euro   It  is  owned  by  the  managers  who  joined  the  company  one   year  acer  its  incorporaJon   13
  • 14. IP  issues   In  both  eMoJon  and  VI-­‐grade  cases  the  support  by  the  TTO   on  the  possibility  of  protecJng  the  products  with  patents   was  non  existent.  There  was  no  “procedure”   The  Italian  law  assigns  the  ownership  of  the  invenJon  and   the  rights  to  the  inventor,  not  to  the  University   Most  TTO  do  not  have  budget  to  cover  the  costs  for  the   deposit  of  the  patent  applicaJon     14
  • 15. The  IP  scenario   The  “top  5”  universiJes  count  at  the  end  of  2008  a   porfolio  of  about  200  patents  each   The  average  of  all  the  universiJes  that  have  a  TTO  is  of   about  40  patents  each   The  investment  in  IP  is,  on  the  average,  of  about  220   thousand  Euro  per  year  for  the  “top  5”  and  of  somewhat   more  than  50  thousand  Euro  for  all  the  universiJes  with  a   TTO   On  the  average  the  “top  5”  close  5  to  7  licensing  deals  per   year  and  all  the  universiJes  1   15
  • 16. The  IP  scenario   The  revenues  generated  by  the  licensing  deals  for  the  “top   5”  universiJes  is  about  150  thousand  Euro  per  year  on   average   Netval,  an  associaJon  of  46  TTO  in  Italy  recently  assigned   to  a  private  company  the  commercializaJon  of  their  IP   16
  • 17. The  minuses  of  the  Italian  scenario   Doctoral  schools     •   There  are  few  students   •   The  basin  of  airacJon  is  local,  few  internaJonal   students   •   Entrepreneurship  is  weak  amongst  the  PhD  students     •   The  recruiJng  process  is  defecJve   The  innova<on  ecosystem   •   There  is  a  limited  M&A  acJvity  on  high  technology   companies   •   The  intangibles  are  ocen  not  considered  in  the   evaluaJon  of  a  company   •   There  is  no  altude  to  design  companies  that  work  in   the  early  stages  of  the  supply  chain  offering  IP   17
  • 18. The  pluses  of  the  Italian  scenario   Opportuni<es   •   There  are  numerous  pockets  of  excellency  in  research   Italy  is  the  third  country  in  the  world  for  number  of   scienJfic  publicaJons   •   Engineers  are  prepared,  skilled,  loyal  and  do  not  cost   astronomically   •   Funds  are  becoming  available,  see  for  example  the   Fondo  Italiano  di  InvesJmento   •   The  UE  is  pushing  on  the  local  regional  governments   to  support  the  creaJon  of  new  ventures   •   The  quality  of  life  is  high  and  can  airact  skilled   managers  and  researchers  from  abroad   18
  • 19. The  needs  of  the  Italian  scenario   Doctoral  schools  and  research   •   InternazionalizaJon   •   Stronger  and  focused  public  investments  on  doctoral   programs   •   Support  for  hiring  few  qualified  research  managers,   world  famous  scienJsts  capable  of  managing  large  labs   The  innova<on  eco  system   •   Build  the  innovaJon  supply  chain  starJng  from   companies  accellerators  linked  to  early  stage  venture   capitals   •   Focus  on  the  global  market  for  the  M&A  acJvity   19
  • 20. What  does  M31  do?   M31  Italia  turns  innovaJve  technologies  into  start-­‐ ups.   M31  USA  turns  technology  start-­‐ups  into  successful   global  companies.   M31  was  incubated  in  Startcube  the  University  of   Padova  start  up  accellerator   20