4. Henry Wentworth AclandHenry Wentworth Acland
Regius Professor ofRegius Professor of
Medicine, 1857-94Medicine, 1857-94
Helped to found theHelped to found the
Honour School ofHonour School of
Natural Science,Natural Science,
18501850
Championed theChampioned the
building of thebuilding of the
University MuseumUniversity Museum
6. Aims and objectivesAims and objectives
DiscoverDiscover
PreservePreserve
PromotePromote
7. Survey workSurvey work
Survey of archives of RegiusSurvey of archives of Regius
Professors of Medicine at Oxford,Professors of Medicine at Oxford,
1900-20001900-2000
Survey of all clinical and non-clinicalSurvey of all clinical and non-clinical
departments in the Medical Sciencesdepartments in the Medical Sciences
DivisionDivision
8. Records of the RegiusRecords of the Regius
Professors of MedicineProfessors of Medicine
J.S. BurdonJ.S. Burdon
SandersonSanderson
Regius Professor ofRegius Professor of
MedicineMedicine
1895-19041895-1904
9. Acquisitions, 2011-2014Acquisitions, 2011-2014
Hugh CairnsHugh Cairns
Hugh SinclairHugh Sinclair
Dorothy HodgkinDorothy Hodgkin
Rod PorterRod Porter
James GowansJames Gowans
Bronwen LoderBronwen Loder
David WeatherallDavid Weatherall
Louise JohnsonLouise Johnson
13. Rodney Robert PorterRodney Robert Porter
(1917-1985) immunologist(1917-1985) immunologist
Hand-colouredHand-coloured
lantern slidelantern slide
showing equipmentshowing equipment
demonstratingdemonstrating
columncolumn
chromatography,chromatography,
19571957
14. James L. GowansJames L. Gowans (b.1924)(b.1924)
immunologistimmunologist
A humanA human
lymphocyte, viewedlymphocyte, viewed
under an electronunder an electron
microscope.microscope.
Gowans discoveredGowans discovered
the life-cycle of thethe life-cycle of the
lymphocyte in 1959.lymphocyte in 1959.
15. Bronwen LoderBronwen Loder (b.1932)(b.1932)
biochemist and scientific administratorbiochemist and scientific administrator
29. Preserving ModernPreserving Modern
Science CollectionsScience Collections
The papers of geneticists Sir WalterThe papers of geneticists Sir Walter
Bodmer and Lady Julia BodmerBodmer and Lady Julia Bodmer
30. Genetics archive projectsGenetics archive projects
– the landscape– the landscape
The Bodmers – biographyThe Bodmers – biography
and the collectionand the collection
Archivists and modernArchivists and modern
science collections:science collections:
challenges and solutionschallenges and solutions
PreservationPreservation
InterpretationInterpretation
Access – Data Protection ActAccess – Data Protection Act
31. 1. Cataloguing Projects1. Cataloguing Projects
(Bodleian Library, Oxford) Cataloguing the Papers of(Bodleian Library, Oxford) Cataloguing the Papers of
Sir Walter and Lady Julia Bodmer (Saving OxfordSir Walter and Lady Julia Bodmer (Saving Oxford
Medicine)Medicine)
(Edinburgh University Library) ‘Towards Dolly:(Edinburgh University Library) ‘Towards Dolly:
Edinburgh, Roslin and the Birth of Modern Genetics’Edinburgh, Roslin and the Birth of Modern Genetics’
(John Innes Research Centre, Norwich) ‘Cataloguing(John Innes Research Centre, Norwich) ‘Cataloguing
the archives of William Bateson and Cyril D. Darlington’the archives of William Bateson and Cyril D. Darlington’
(Kings College, London) ‘DNA and Social(Kings College, London) ‘DNA and Social
Responsibility: Cataloguing and preserving the papersResponsibility: Cataloguing and preserving the papers
33. 3. Human Genome Archive Project3. Human Genome Archive Project
Scoping initiative launched 2012 byScoping initiative launched 2012 by
Wellcome LibraryWellcome Library
Survey of archives created duringSurvey of archives created during
Human Genome Project (1977-2004)Human Genome Project (1977-2004)
Emphasis on harvesting born-digitalEmphasis on harvesting born-digital
material – saving contemporarymaterial – saving contemporary
sciencescience
34. SummarySummary
Substantial body of genetics resources nowSubstantial body of genetics resources now
availableavailable
Network of archivists working on scienceNetwork of archivists working on science
collectionscollections
Bodmer project at Bodleian contributes
significantly towards wider documentation of
this crucial field of scientific endeavour
35. Walter Bodmer (b. 1936)Walter Bodmer (b. 1936)
Manchester Grammar SchoolManchester Grammar School
Cambridge University (1956-60) –Cambridge University (1956-60) –
Undergrad/Ph.D (Undergrad/Ph.D (maths, statistics, population genetics)maths, statistics, population genetics)
Stanford University (1961-69)Stanford University (1961-69)
Oxford University (1970-79) – First ProfessorOxford University (1970-79) – First Professor
of Geneticsof Genetics
Imperial Cancer Research Fund, Director ofImperial Cancer Research Fund, Director of
Research, Director-General (1980-96)Research, Director-General (1980-96)
Principal of Hertford Collection, OxfordPrincipal of Hertford Collection, Oxford
University (1996-2005)University (1996-2005)
Head of Cancer and Immunogenetics Lab,Head of Cancer and Immunogenetics Lab,
Weatherall Institute of Molecular Medicine,Weatherall Institute of Molecular Medicine,
Oxford (1996- present day)Oxford (1996- present day)
36. Julia Bodmer (1934-2001)Julia Bodmer (1934-2001)
State scholarship from ManchesterState scholarship from Manchester
High School to read (PPE) at OxfordHigh School to read (PPE) at Oxford
UniversityUniversity
Statistical Assistant, CambridgeStatistical Assistant, Cambridge
University (1956-60)University (1956-60)
Research Assistant, StanfordResearch Assistant, Stanford
University (1961-69)University (1961-69)
Research Officer, GeneticsResearch Officer, Genetics
Laboratory, Oxford UniversityLaboratory, Oxford University
(1970-79)(1970-79)
Head of Tissue AntigenHead of Tissue Antigen
Laboratory, ICRF, London (1980-Laboratory, ICRF, London (1980-
96)96)
Joint Head of Cancer andJoint Head of Cancer and
Immunogenetics Lab, WeatherallImmunogenetics Lab, Weatherall
Institute of Molecular Medicine,Institute of Molecular Medicine,
Oxford (1996-2001)Oxford (1996-2001)
37. ““To my wife, please doTo my wife, please do
not shred all mynot shred all my
papers!”papers!”
48. Interpretation - solutionsInterpretation - solutions
Work in partnership with donor/recordWork in partnership with donor/record
creator if possible – build a relationshipcreator if possible – build a relationship
Connections with other archivistsConnections with other archivists
Consult externally – scientists, medicalConsult externally – scientists, medical
profession, historians, etc.profession, historians, etc.
49. Access and Legislation –Access and Legislation –
challengeschallenges
Data Protection Act – sensitive personal dataData Protection Act – sensitive personal data
Finding balance between providing accessFinding balance between providing access
with protecting individual’s privacywith protecting individual’s privacy
Over 1/3 of collection has some level ofOver 1/3 of collection has some level of
sensitivitysensitivity
50. Sensitive or confidentialSensitive or confidential
material in Bodmer archivematerial in Bodmer archive
Named blood donor dataNamed blood donor data
Named donor data of families and family treesNamed donor data of families and family trees
Photographs of individual’s which reveal medical conditionsPhotographs of individual’s which reveal medical conditions
Hospital patient lists/records (structured case notes or informal)Hospital patient lists/records (structured case notes or informal)
Grant applications containing confidential references/statements ofGrant applications containing confidential references/statements of
opinionopinion
ICRF personnel files incl. staff appraisals, staff appointments,ICRF personnel files incl. staff appraisals, staff appointments,
pension details, etc.pension details, etc.
References and recommendationsReferences and recommendations
Corporate confidentiality – high level meetingsCorporate confidentiality – high level meetings
Opinions on staff, other scientists and their researchOpinions on staff, other scientists and their research
Nominations for Royal Society, Nobel Prize, etc.Nominations for Royal Society, Nobel Prize, etc.
Architectural plans of research units identifying location of animal-Architectural plans of research units identifying location of animal-
houseshouses
51. Access and Legislation:Access and Legislation:
solutionssolutions
Forward plan: identify common types ofForward plan: identify common types of
sensitivities early– make consistentsensitivities early– make consistent
decisions on ‘closed’ datadecisions on ‘closed’ data
Targeted correspondence, partiallyTargeted correspondence, partially
restricted boxes that were originally markedrestricted boxes that were originally marked
for full closure – 70 % correspondencefor full closure – 70 % correspondence
opened upopened up
Genetics Laboratory- c. 1973Same step outside Physiology building – Hugh Sinclair Archive 1894
Other geneticists not included in this list of digitised archives include: Peter Medewar, Arthur Mourant, Lionel Penrose and Gerard Wyatt
Chromatography : Gel electrophoresis (papers have shiny film): developed from the 1970s - method of analysing DNA by using electricity to charge the molecules and separate DNA fragments as they pass through a gel matrix. (monkey spleen fusions to produce antibody) Used in Western blotting or Southern blotting tests.
Colorectal cell lines
Western blot tests – uses gel electrophoresis to separate proteins making it possible to identify specific proteins; Southern blotting is used for the detection of a specific DNA sequence
Very small selection - over 100 boxes –chromatography dyes contain carcinogens- traces on filter paper that fluoresced under UV light