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12
The Cardiovascular
System: Transport and
Supply
Part One
Cardiovascular
System


Cardiovascular
system
transports
nutrients and
oxygen to cells
in body while
carbon dioxide
and waste
products of
cells' metabolism
are removed
Cardiovascular
System

Pump that
circulates the
transport
medium
(blood) is the
heart
System Overview


The circulatory
The circulatory
system uses the
system uses the
heart as a
heart as a
pump and
pump and
transports
transports
through blood
through blood
vessels to
vessels to
organs and the
organs and the
smallest
smallest
tissues and
tissues and
cell
cell
Cardiovascular
System

Cardiovascular
System

 Veins differ from arteries
because they carry
blood toward heart,
have valves, and have
thinner walls; they are
more numerous and have
larger capacity
Figure 12-1
Four Functions of the
Cardiovascular system.



FOUR FUNCTIONS
How the Heart Works


https://www.youtube.com/watch?v=oZ1_TAwCUWw
The Heart


The size of your fist
and located slightly
left of center of chest.

Base is
proximal to
your head
while apex is
distal
The Heart


Pericardium includes
the parietal and
visceral layers with
potential cavity
The Heart


3 layers to heart:
•Outer: Epicardium
•Middle: Myocardium
•Inner endocardium
The Heart

Although heart is one
single organ, it is easier
to understand if you
think of it as two
pumps working
together
.
The Heart

Right side collects
blood from body and
sends it to lungs; left
side collects blood
from lungs and sends
it to rest of body
.
Chambers of the
Heart

Four chambers in
heart
Two chambers on left
side are separated
from two chambers
on right side by wall
called septum
Septums of the Heart

Wall between
upper, smaller
chambers (atria)
is interatrial
septum
Wall between two
larger chambers
(ventricles) is
interventricular
septum
Figure 12-2
The anatomy of the heart


Flow of blood through
the Heart

 Two large veins
that return blood
from the body to
right atrium are
superior (SVC)
and inferior (IVC)
vena cava
Flow of blood through
the Heart


 Right atrium (RAtr)
(locations are
based on patient’s
perspective) is
collecting chamber
where blood is
returned to heart
after trip around
the body
FIRST
Flow of blood through
the Heart


 Blood travels from
right atrium,
through one-way
atrioventricular
valve called
tricuspid valve
(TCVa) , and into
right ventricle
(RVe)
Flow of blood through
the Heart


 When right ventricle
is full of blood, heart
contracts; tricuspid
valve prevents
backflow and so
blood flows through
pulmonary valve
(PVa) to pulmonary
arteries (PA)
Second
Flow of blood through
the Heart


 Right pulmonary
artery (PA)* goes
to right lung, left
pulmonary artery
(PA) goes to left
lung

*Remember: Arteries go
AWAY from the heart
THIRD
Flow of blood through
the Heart

Vessels then get
smaller and
smaller,
eventually
ending in
capillaries
around each air
sac (alveolus);
Flow of blood through
the Heart

Blood then returns
to heart via left
(LPV) and right
pulmonary (RPV)
veins*
*Remember: Veins go
TOWARD the heart
Flow of blood through
the Heart


Pulmonary veins
return blood to left
atrium (LAtr).
Blood flows through
atrioventricular
valve, called mitral
valve (MiVa) , and
into left ventricle
(LVe)

Fourth
Flow of blood through
the Heart


Ventricular pressure
increases as it fills,
and heart
contracts forcing
mitral valve closed,
blood is ejected
through aortic
valve (Ava) to
aorta, and then out
to rest of body

Fifth
Figure 12-3
The functioning of heart valves
and blood flow.


Flow of Blood through
the Heart

Blood is
ejected
during
systole, or
contraction (of
ventricles)
phase
Flow of Blood through
the Heart


Both atria fill at
same time, both
ventricles fill at
same time, and
both ventricles
eject blood at
same time when
heart contracts
Flow of Blood through
the Heart


After blood is
ejected from
ventricles, heart
enters resting
period called
diastole
During diastole,
ventricles fill
with blood
Flow of Blood through
the Heart

Contraction
begins at
apex and
travels
upward
Flow of Blood through
the Heart


Valve located at
exit to each
chamber because
the circulatory
system is a
pressurized system
and valves
prevent any
ejected blood
from flowing
backwards
Measuring Heart Rate

Heart rate is
measured by
counting rhythmic
expansion and
contraction of
arteries due to
opening & closing
of the aortic
semilunar valves
Measuring Heart Rate

The Heart

Atrial walls are
thinner than
ventricular walls
Higher
pressures are
generated in
ventricles to
move blood
throughout entire
body

THIN WALL

THICK WALL
Coronary Arteries

Portion of newly
oxygen-enriched
blood leaving
heart is diverted
from aorta by
right and left
coronary
arteries
Figure 12-4
Coronary circulation.



Regular aerobic
exercise improves the
ability of the heart to
increase the density
(number of vessels in
one area) of blood
vessels that branch
from the main
coronary arteries.
Coronary Circulation

By increasing the

density of blood
vessels that branch
off the main arteries,
there will be
alternate routes for
blood to travel in
case of a blockage
and decrease risk
of myocardial
infarction
Figure 12-6
Atherosclerosis.



Fatty deposits called plaque
develop on the inside of the
blood vessels and restrict
flow
Mainly the aorta, coronary
arteries and cerebral
arteries are effected
Why do you think this is?
PA/Instructor Asks:

The material that deposits in the
arteries is made up mainly of:
A. Glucose
B. Calcium
C. Cholesterol
D. Protein
PA/Instructor Asks:

The material that deposits in the
arteries is made up mainly of:
A. Glucose
B. Calcium
C. Cholesterol
D. Protein
Electrical System of
the Heart



Cardiac muscle is
auto rhythmic,
meaning it can
contract
without nerve
impulses or
hormones
Electrical System of
the Heart



There are
specialized
cardiac cells that
create and
distribute
electrical current
that causes
controlled and
directed
contraction of
heart
Electrical System of
the Heart

Nodal cells, or
pacemaker cells,
are specialized cells
that not only
create electrical
impulse, but
create impulses at
regular interval
Electrical System
of theHeart
The Electric Pathway

Sino atrial node
sends impulse to
atrio ventricular
node before AV
node can send
signal
The Electric Pathway

However, atrio
ventricular node
acts as backup if
sinoatrial node fails to
fire, resulting in
slower heartbeat
due to reduced firing
rate
Figure 12-9
Conduction system of the
heart.


•• SA node causes
SA node causes
atria to contract
atria to contract
•• Stimulus arrives
Stimulus arrives
at AV node
at AV node
•• Follows AV
Follows AV
bundle and
bundle and
travels through
travels through
apex branches
apex branches
•• Purkinjie fibers
Purkinjie fibers
stimulate
stimulate
ventricles to
ventricles to
contract
contract
Factors Affecting
Heart Rate

Factors Affecting
Heart Rate

Low
potassium
can lead to
weak
heartbeat,
while high
calcium can
prolong heart
muscle
contractions to
point where
heart can
stop beating
Factors that Affect
Heart Rate

EKG & Electrical Activity

 EKG represents
Normal

•P wave-impulse generated
by SA node, atria contract
•QRS wave-Depolarization
of ventricles right before
ventricles contract
•T wave-repolarization of
ventricles when they are at
rest before next beat
Figure 12-10
Typical ECG tracing.


Take A Break

Problems with the Pump


Problems with the
Pump

Problems with the
Pump

Problems with the
Pump

Figure 12-20
The multisystem effects of heart
failure.



•
•
•
•
•
•
•

Page 336
Page 336

Neurologic
Respiratory
Cardiovascular
Gastrointestinal
Genitourinary
Musculoskeletal
Metabolic Processes
Heart Attack & CPR


CPR consists of artificial
blood circulation & artificial
respirations. It’s purpose is
to maintain a flow of
oxygenated blood to the
brain and heart

Watch video on “Myocardial Infarction”
Ventricular Assist Devicea bridge to transplant



http://abcnews.go.com/
Blood Vessels

Blood leaves heart

through aorta,
which branches into
large vessels called
arteries
Arteries divide into
smaller and smaller
vessels, smallest of
which are called
arterioles
Blood Vessels
 Arterioles feed into

capillaries that
form capillary beds
in body's tissues,
allowing oxygen
and nutrients to
infuse into cells
and picking up
carbon dioxide
and waste
products for
removal
Blood Vessels

Diameter of only
0.008 mm (slightly
larger than
diameter of single
red blood cell) Allow
easy movement
of oxygen and
nutrients through
wall, while carbon
dioxide and
wastes can move
into blood
Blood Vessels
 Blood then makes

its return trip to the
heart by draining
into tiny venules,
which combine into
veins which
eventually become
great veins (SVC
and IVC) that
return to heart
Figure 12-15
B. Locations of major arteries.
C. Locations of the major veins.


Blood Vessel
Structure  Function
&
Blood Vessel
Structure  Function
&
Figure 12-16
Blood pressure measurement.



Done with a
stethoscope and
sphygmomanometer
an inflatable cuff
placed around the arm,
so that when it is
inflated, it squeezes
brachial artery shut
Figure 12-16
Blood pressure measurement.



Stethoscope placed
over artery near elbow
and cuff inflated until
30 mm Hg past the
point that pulse no
longer heard.
Open release valve
slightly
Figure 12-16
Blood pressure measurement.



Listen for sound of blood
coming through artery,
which is the peak
systolic pressure (top
number)
Cuff pressure
decreases until sound is
not heard. The last sound
is diastolic pressure
(lower number)
Elevated Blood Pressure


Desirable blood pressure is:
•Systolic - from 90 to 119
•Diastolic - from 60 to 79
Prehypertension is:
•Systolic-from 120 to 139
•Diastolic- from 80- 89
Hypertension is:
•Systolic over 140
•Diastolic over 90
Plugging the “Leaks” of
Blood Vessels



CV system is closed
and pressurized
system
If break or leak in
system couldn't be
stopped, you would
lose large amount of
blood
Several substances in
blood plug leaks

Fibrin traps blood cells and
platelets to form blood clot
Plugging the “Leaks” of
Blood Vessels



When inner wall of
vessel is damaged,
underlying collagen
fiber becomes
exposed
Platelets floating in
blood begin to attach
to that rough
damaged site
Plugging the “Leaks” of
Blood Vessels



Attached platelets
release several
chemicals that draw
more platelets,
creating platelet plug
Clotting Process

Platelets
secrete
serotonin,
which causes
blood vessels
to spasm,
decreasing
blood flow to
that area
Clotting Process


Fibrin forms netlike
patch at site of
injury, snagging
more blood cells
and platelets;
within 3 to 6
minutes a clot is
created
Fibrin traps blood cells and
platelets to form blood clot
Clotting Process
Once clot is formed,
it begins to retract
and pulls edges of
damaged tissue
together allowing
edges to
regenerate
necessary
epithelial cells to
make permanent
repair over time


Figure 12-18
The clotting process.


WEAR YOUR ASSIGNED
COLOR



Meet here at Room 108 on
Thursday and we’ll go to room
over in AAR building for
exercise
Complete Handout “Heart
Activity” as you will need to
hand that in at the end of
Thursday’s class for credit
“The Heart Activity”


Work on the handout
“The Heart Activity”
Read through the first
two pages on the
Blood Flow
Sequence. The third
page shows structure
of the heart.
Complete the 15
questions on back
page

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Survey of Anatomy and Physiology Chap 12 Part One

  • 2. Cardiovascular System  Cardiovascular system transports nutrients and oxygen to cells in body while carbon dioxide and waste products of cells' metabolism are removed
  • 4. System Overview  The circulatory The circulatory system uses the system uses the heart as a heart as a pump and pump and transports transports through blood through blood vessels to vessels to organs and the organs and the smallest smallest tissues and tissues and cell cell
  • 6. Cardiovascular System   Veins differ from arteries because they carry blood toward heart, have valves, and have thinner walls; they are more numerous and have larger capacity
  • 7. Figure 12-1 Four Functions of the Cardiovascular system.  FOUR FUNCTIONS
  • 8. How the Heart Works  https://www.youtube.com/watch?v=oZ1_TAwCUWw
  • 9. The Heart  The size of your fist and located slightly left of center of chest. Base is proximal to your head while apex is distal
  • 10. The Heart  Pericardium includes the parietal and visceral layers with potential cavity
  • 11. The Heart  3 layers to heart: •Outer: Epicardium •Middle: Myocardium •Inner endocardium
  • 12. The Heart  Although heart is one single organ, it is easier to understand if you think of it as two pumps working together .
  • 13. The Heart  Right side collects blood from body and sends it to lungs; left side collects blood from lungs and sends it to rest of body .
  • 14. Chambers of the Heart  Four chambers in heart Two chambers on left side are separated from two chambers on right side by wall called septum
  • 15. Septums of the Heart  Wall between upper, smaller chambers (atria) is interatrial septum Wall between two larger chambers (ventricles) is interventricular septum
  • 16. Figure 12-2 The anatomy of the heart 
  • 17. Flow of blood through the Heart   Two large veins that return blood from the body to right atrium are superior (SVC) and inferior (IVC) vena cava
  • 18. Flow of blood through the Heart   Right atrium (RAtr) (locations are based on patient’s perspective) is collecting chamber where blood is returned to heart after trip around the body FIRST
  • 19. Flow of blood through the Heart   Blood travels from right atrium, through one-way atrioventricular valve called tricuspid valve (TCVa) , and into right ventricle (RVe)
  • 20. Flow of blood through the Heart   When right ventricle is full of blood, heart contracts; tricuspid valve prevents backflow and so blood flows through pulmonary valve (PVa) to pulmonary arteries (PA) Second
  • 21. Flow of blood through the Heart   Right pulmonary artery (PA)* goes to right lung, left pulmonary artery (PA) goes to left lung *Remember: Arteries go AWAY from the heart THIRD
  • 22. Flow of blood through the Heart  Vessels then get smaller and smaller, eventually ending in capillaries around each air sac (alveolus);
  • 23. Flow of blood through the Heart  Blood then returns to heart via left (LPV) and right pulmonary (RPV) veins* *Remember: Veins go TOWARD the heart
  • 24. Flow of blood through the Heart  Pulmonary veins return blood to left atrium (LAtr). Blood flows through atrioventricular valve, called mitral valve (MiVa) , and into left ventricle (LVe) Fourth
  • 25. Flow of blood through the Heart  Ventricular pressure increases as it fills, and heart contracts forcing mitral valve closed, blood is ejected through aortic valve (Ava) to aorta, and then out to rest of body Fifth
  • 26. Figure 12-3 The functioning of heart valves and blood flow. 
  • 27. Flow of Blood through the Heart  Blood is ejected during systole, or contraction (of ventricles) phase
  • 28. Flow of Blood through the Heart  Both atria fill at same time, both ventricles fill at same time, and both ventricles eject blood at same time when heart contracts
  • 29. Flow of Blood through the Heart  After blood is ejected from ventricles, heart enters resting period called diastole During diastole, ventricles fill with blood
  • 30. Flow of Blood through the Heart  Contraction begins at apex and travels upward
  • 31. Flow of Blood through the Heart  Valve located at exit to each chamber because the circulatory system is a pressurized system and valves prevent any ejected blood from flowing backwards
  • 32. Measuring Heart Rate  Heart rate is measured by counting rhythmic expansion and contraction of arteries due to opening & closing of the aortic semilunar valves
  • 34. The Heart  Atrial walls are thinner than ventricular walls Higher pressures are generated in ventricles to move blood throughout entire body THIN WALL THICK WALL
  • 35. Coronary Arteries  Portion of newly oxygen-enriched blood leaving heart is diverted from aorta by right and left coronary arteries
  • 36. Figure 12-4 Coronary circulation.  Regular aerobic exercise improves the ability of the heart to increase the density (number of vessels in one area) of blood vessels that branch from the main coronary arteries.
  • 37. Coronary Circulation  By increasing the density of blood vessels that branch off the main arteries, there will be alternate routes for blood to travel in case of a blockage and decrease risk of myocardial infarction
  • 38. Figure 12-6 Atherosclerosis.  Fatty deposits called plaque develop on the inside of the blood vessels and restrict flow Mainly the aorta, coronary arteries and cerebral arteries are effected Why do you think this is?
  • 39. PA/Instructor Asks:  The material that deposits in the arteries is made up mainly of: A. Glucose B. Calcium C. Cholesterol D. Protein
  • 40. PA/Instructor Asks:  The material that deposits in the arteries is made up mainly of: A. Glucose B. Calcium C. Cholesterol D. Protein
  • 41. Electrical System of the Heart  Cardiac muscle is auto rhythmic, meaning it can contract without nerve impulses or hormones
  • 42. Electrical System of the Heart  There are specialized cardiac cells that create and distribute electrical current that causes controlled and directed contraction of heart
  • 43. Electrical System of the Heart  Nodal cells, or pacemaker cells, are specialized cells that not only create electrical impulse, but create impulses at regular interval
  • 45. The Electric Pathway  Sino atrial node sends impulse to atrio ventricular node before AV node can send signal
  • 46. The Electric Pathway  However, atrio ventricular node acts as backup if sinoatrial node fails to fire, resulting in slower heartbeat due to reduced firing rate
  • 47. Figure 12-9 Conduction system of the heart.  •• SA node causes SA node causes atria to contract atria to contract •• Stimulus arrives Stimulus arrives at AV node at AV node •• Follows AV Follows AV bundle and bundle and travels through travels through apex branches apex branches •• Purkinjie fibers Purkinjie fibers stimulate stimulate ventricles to ventricles to contract contract
  • 49. Factors Affecting Heart Rate  Low potassium can lead to weak heartbeat, while high calcium can prolong heart muscle contractions to point where heart can stop beating
  • 51. EKG & Electrical Activity  EKG represents Normal •P wave-impulse generated by SA node, atria contract •QRS wave-Depolarization of ventricles right before ventricles contract •T wave-repolarization of ventricles when they are at rest before next beat
  • 52. Figure 12-10 Typical ECG tracing. 
  • 54. Problems with the Pump 
  • 58. Figure 12-20 The multisystem effects of heart failure.  • • • • • • • Page 336 Page 336 Neurologic Respiratory Cardiovascular Gastrointestinal Genitourinary Musculoskeletal Metabolic Processes
  • 59. Heart Attack & CPR  CPR consists of artificial blood circulation & artificial respirations. It’s purpose is to maintain a flow of oxygenated blood to the brain and heart Watch video on “Myocardial Infarction”
  • 60. Ventricular Assist Devicea bridge to transplant  http://abcnews.go.com/
  • 61. Blood Vessels  Blood leaves heart through aorta, which branches into large vessels called arteries Arteries divide into smaller and smaller vessels, smallest of which are called arterioles
  • 62. Blood Vessels  Arterioles feed into capillaries that form capillary beds in body's tissues, allowing oxygen and nutrients to infuse into cells and picking up carbon dioxide and waste products for removal
  • 63. Blood Vessels  Diameter of only 0.008 mm (slightly larger than diameter of single red blood cell) Allow easy movement of oxygen and nutrients through wall, while carbon dioxide and wastes can move into blood
  • 64. Blood Vessels  Blood then makes its return trip to the heart by draining into tiny venules, which combine into veins which eventually become great veins (SVC and IVC) that return to heart
  • 65. Figure 12-15 B. Locations of major arteries. C. Locations of the major veins. 
  • 68. Figure 12-16 Blood pressure measurement.  Done with a stethoscope and sphygmomanometer an inflatable cuff placed around the arm, so that when it is inflated, it squeezes brachial artery shut
  • 69. Figure 12-16 Blood pressure measurement.  Stethoscope placed over artery near elbow and cuff inflated until 30 mm Hg past the point that pulse no longer heard. Open release valve slightly
  • 70. Figure 12-16 Blood pressure measurement.  Listen for sound of blood coming through artery, which is the peak systolic pressure (top number) Cuff pressure decreases until sound is not heard. The last sound is diastolic pressure (lower number)
  • 71. Elevated Blood Pressure  Desirable blood pressure is: •Systolic - from 90 to 119 •Diastolic - from 60 to 79 Prehypertension is: •Systolic-from 120 to 139 •Diastolic- from 80- 89 Hypertension is: •Systolic over 140 •Diastolic over 90
  • 72. Plugging the “Leaks” of Blood Vessels  CV system is closed and pressurized system If break or leak in system couldn't be stopped, you would lose large amount of blood Several substances in blood plug leaks Fibrin traps blood cells and platelets to form blood clot
  • 73. Plugging the “Leaks” of Blood Vessels  When inner wall of vessel is damaged, underlying collagen fiber becomes exposed Platelets floating in blood begin to attach to that rough damaged site
  • 74. Plugging the “Leaks” of Blood Vessels  Attached platelets release several chemicals that draw more platelets, creating platelet plug
  • 75. Clotting Process  Platelets secrete serotonin, which causes blood vessels to spasm, decreasing blood flow to that area
  • 76. Clotting Process  Fibrin forms netlike patch at site of injury, snagging more blood cells and platelets; within 3 to 6 minutes a clot is created Fibrin traps blood cells and platelets to form blood clot
  • 77. Clotting Process Once clot is formed, it begins to retract and pulls edges of damaged tissue together allowing edges to regenerate necessary epithelial cells to make permanent repair over time 
  • 79. WEAR YOUR ASSIGNED COLOR  Meet here at Room 108 on Thursday and we’ll go to room over in AAR building for exercise Complete Handout “Heart Activity” as you will need to hand that in at the end of Thursday’s class for credit
  • 80. “The Heart Activity”  Work on the handout “The Heart Activity” Read through the first two pages on the Blood Flow Sequence. The third page shows structure of the heart. Complete the 15 questions on back page

Editor's Notes

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