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Recruitment Of An Unexposed Control Group For A Pregnancy Registry   Teratology Society Annual Meeting June 2008 Monterey, California Caitlin R. Smith, M.P.H Lewis B. Holmes, M.D. North American Antiepileptic Drug Pregnancy Registry MassGeneral Hospital for Children, Boston, MA
Pregnancy Registries and Control Groups ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],AED Pregnancy Registry TOLL FREE:  1-888-233-2334 www.AEDPregnancyRegistry.org
Strategy for Comparison Group  ,[object Object],[object Object],[object Object]
Exposed vs. Massachusetts Births *Based on data from AED Pregnancy Registry  ** From MA births 2000, http://www.mass.gov/dph/bhsre/birth/birth2000.pdf  § Question asked after 01/01/2000
Exposed Control Submitters vs. Unexposed *Based on data from AED Pregnancy Registry  § Question asked after 01/01/2000
Techniques for Recruiting Controls   Telephone Scripts ,[object Object],[object Object],[object Object],PRO :     CON : - captive audience   - time consuming - consistent execution   - information overload - inexpensive   - easy for pt. to forget
Techniques for Recruiting Controls (cont’d):   Direct Mail Campaigns ,[object Object],[object Object],[object Object],PRO :     CON : - longer shelf life     - expensive - broad distribution   - subject to delivery failure - brand recognition   - junk mail
Techniques for Recruiting Controls (cont’d):  Email & Web Campaigns ,[object Object],[object Object],[object Object],PRO :     CON : - inexpensive     - easily ignored - targeted recipients   - subject to delivery failure - easy to share/forward  - limited audience
Cumulative Enrollment w/ Methods ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Enrollment  with Methods ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],RA turnover
Conclusions  ,[object Object],[object Object],[object Object]

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Recruitment Of An Unexposed Control Group For A Pregnancy Registry

  • 1. Recruitment Of An Unexposed Control Group For A Pregnancy Registry Teratology Society Annual Meeting June 2008 Monterey, California Caitlin R. Smith, M.P.H Lewis B. Holmes, M.D. North American Antiepileptic Drug Pregnancy Registry MassGeneral Hospital for Children, Boston, MA
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  • 5. Exposed vs. Massachusetts Births *Based on data from AED Pregnancy Registry ** From MA births 2000, http://www.mass.gov/dph/bhsre/birth/birth2000.pdf § Question asked after 01/01/2000
  • 6. Exposed Control Submitters vs. Unexposed *Based on data from AED Pregnancy Registry § Question asked after 01/01/2000
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Notas del editor

  1. Good Morning, my name is Caitlin Smith and I am the Senior Project Manager at the North American Antiepileptic Drug Pregnancy Registry, located at Massachusetts General Hospital in Boston. I will be presenting our experience with enrolling an unexposed control (or comparison) group for a pregnancy registry.