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Diagnostic Fetal Assessment
            tests

  Sandy Warner RNC-OB, MSN
        August 3, 2011
    Inpatient Review Class
Prenatal Assessments and
            screening
   Chorionic Villous sampling:
       10-12 wk using U/S to aspirate
        trophoblastic tissue
       Can be done either transabdominally or
        transvaginally
       Detects chromosome abnormality
       Risks: miscarriage, bleeding, infection &
        PROM
Prenatal Assessments and
          screening cont.
   Triple or Quad Screen
       Blood drawn between 15-20 wks
       Can detect Down’s syndrome, other
        chromosomal abnormalities and neural
        tube defects
       Values of blood tests added together to
        determine risk
       Screening tool – further testing needed for
        definitive diagnosis
Ultrasound
   Developed in WWII with submarines

   Diagnostic use since 1950s

   Definition: transmission of sound
    waves to investigate an object
            (Kline-Fath & Bitters, 2007)
Placental grading
   Grade 0 – smooth, dense w/o
    echogenic areas
   Grade 1 – undulations present, some
    echogenic areas
   Grade 2 – deeper and > indentations,
    more echogenic areas
   Grade 3 – dense echogenic areas w/
    indentations, areas of calcification
Amniocentesis
   Trans-abdominal needle aspiration of
    10-20 ml of amniotic fluid for lab
    analysis
   Done under ultrasound
   Requires sterile technique and time out
Amniocentesis

   Indications:
       Genetic
       R/O infection
       Fetal lung maturity
       Assess for bilirubin with hemolytic
        incompatibility
Amniocentesis
   Timing:
       Early – performed between 11-14 wks
            Significantly higher pregnancy loss
            Post procedure fluid loss
       2nd trimester – performed between 15-20 wks
            Usually for genetic screening
       3rd trimester
            Usually for fetal lung maturity
                      (Gilbert, 4th edition, pg 93)
Cordocentesis /
Fetal Blood Transfusion

   Blood Transfusion for
    anemia
       How much blood is
        given?
       Graph is used correlating
        the hematocrit of donor
        blood to the hematocrit of
        the fetus to determine
        donor blood volume to be
        given
Cordocentesis /
Fetal Blood Transfusion
Amnioreduction
   Reduces amount of amniotic fluid
    around fetus
   Procedure like amniocentesis only with
    tubing to suction canister or stopcock
   Done to relieve maternal symptoms or
    with twin to twin transfusion syndrome
Amnioreduction
Fetal MRI
   Superior soft tissue contrast test
   Does not use radiation
   Used for fetal brain, spinal deformities,
    lesions, masses
       Also can assess placental and cord malformations
   Also used to measure lung volume
            Research still continuing for PPROM pts
                      (Kline-Fath & Bitters, 2007)
Fetal MRI Con’t
   Not recommended in first trimester
        (no documented studies on harm
        from heat or sound, but not recommended)

   Not used routinely, only after U/S not able to detect

   Contrast dye not recommended

   Informed consent
           (Kline-Fath & Bitters, 2007)
Fetal Echocardiogram
   Timing: between 18-22 weeks
   Indications:
       Family history congenital heart defects
       Maternal diabetes
       Drug exposure
       Teratogenic exposure
       Chromosomal abnormalities
       Non-immune hydrops
       Maternal PKU
       Fetal arrhythmias
                   Queenan, Hobbins & Spong (4th edition, 2007)
Vibroaccoustic Stimulation (VAS)
   Artificial acoustic stimulation

   Done after 25 wks gestation when fetus can hear

   After 10 minutes of baseline and no
    accelerations, place the artificial larynx on the
    maternal abdomen over the fetal head
Vibroaccoustic Stimulation
   Provide 5-10 sec stimulation near fetal
    head, wait one minute

   If no acceleration repeat cycle for a
    total of three times

   if non-reactive after 40 minutes,
    proceed with further evaluation
Vibroaccoustic Stimulation
   Fetuses 28 weeks or greater respond
    to VAS with a consistent increase in
    heart rate.

   Observed changes are greater as term
    is approached.
Vibroaccoustic Stimulation
(VAS)
References

   Gilbert, E. S., (2011) 5th edition Manual of High Risk
    Pregnancy and Delivery.

   Kline-Fath, B. & Bitters, C. (2007) “Prenatal Imaging”
    Newborn and Infant Nursing Reviews, Vol.7, No. 4.

   Mattson, S. & Smith, J.E., (2011) 4th edition Core
    Curriculum for Maternal-Newborn Nursing.

   Queenan, J.T., Hobbins, J. C., & Spong, C. Y. (2005)
    4th edition, Protocols for High-Risk Pregnancies

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Wiki.diagnostic fetal assessment tests 2011

  • 1. Diagnostic Fetal Assessment tests Sandy Warner RNC-OB, MSN August 3, 2011 Inpatient Review Class
  • 2. Prenatal Assessments and screening  Chorionic Villous sampling:  10-12 wk using U/S to aspirate trophoblastic tissue  Can be done either transabdominally or transvaginally  Detects chromosome abnormality  Risks: miscarriage, bleeding, infection & PROM
  • 3. Prenatal Assessments and screening cont.  Triple or Quad Screen  Blood drawn between 15-20 wks  Can detect Down’s syndrome, other chromosomal abnormalities and neural tube defects  Values of blood tests added together to determine risk  Screening tool – further testing needed for definitive diagnosis
  • 4. Ultrasound  Developed in WWII with submarines  Diagnostic use since 1950s  Definition: transmission of sound waves to investigate an object  (Kline-Fath & Bitters, 2007)
  • 5.
  • 6. Placental grading  Grade 0 – smooth, dense w/o echogenic areas  Grade 1 – undulations present, some echogenic areas  Grade 2 – deeper and > indentations, more echogenic areas  Grade 3 – dense echogenic areas w/ indentations, areas of calcification
  • 7.
  • 8. Amniocentesis  Trans-abdominal needle aspiration of 10-20 ml of amniotic fluid for lab analysis  Done under ultrasound  Requires sterile technique and time out
  • 9. Amniocentesis  Indications:  Genetic  R/O infection  Fetal lung maturity  Assess for bilirubin with hemolytic incompatibility
  • 10. Amniocentesis  Timing:  Early – performed between 11-14 wks  Significantly higher pregnancy loss  Post procedure fluid loss  2nd trimester – performed between 15-20 wks  Usually for genetic screening  3rd trimester  Usually for fetal lung maturity  (Gilbert, 4th edition, pg 93)
  • 11. Cordocentesis / Fetal Blood Transfusion  Blood Transfusion for anemia  How much blood is given?  Graph is used correlating the hematocrit of donor blood to the hematocrit of the fetus to determine donor blood volume to be given
  • 13. Amnioreduction  Reduces amount of amniotic fluid around fetus  Procedure like amniocentesis only with tubing to suction canister or stopcock  Done to relieve maternal symptoms or with twin to twin transfusion syndrome
  • 15. Fetal MRI  Superior soft tissue contrast test  Does not use radiation  Used for fetal brain, spinal deformities, lesions, masses  Also can assess placental and cord malformations  Also used to measure lung volume  Research still continuing for PPROM pts  (Kline-Fath & Bitters, 2007)
  • 16. Fetal MRI Con’t  Not recommended in first trimester (no documented studies on harm from heat or sound, but not recommended)  Not used routinely, only after U/S not able to detect  Contrast dye not recommended  Informed consent  (Kline-Fath & Bitters, 2007)
  • 17. Fetal Echocardiogram  Timing: between 18-22 weeks  Indications:  Family history congenital heart defects  Maternal diabetes  Drug exposure  Teratogenic exposure  Chromosomal abnormalities  Non-immune hydrops  Maternal PKU  Fetal arrhythmias  Queenan, Hobbins & Spong (4th edition, 2007)
  • 18. Vibroaccoustic Stimulation (VAS)  Artificial acoustic stimulation  Done after 25 wks gestation when fetus can hear  After 10 minutes of baseline and no accelerations, place the artificial larynx on the maternal abdomen over the fetal head
  • 19. Vibroaccoustic Stimulation  Provide 5-10 sec stimulation near fetal head, wait one minute  If no acceleration repeat cycle for a total of three times  if non-reactive after 40 minutes, proceed with further evaluation
  • 20. Vibroaccoustic Stimulation  Fetuses 28 weeks or greater respond to VAS with a consistent increase in heart rate.  Observed changes are greater as term is approached.
  • 22. References  Gilbert, E. S., (2011) 5th edition Manual of High Risk Pregnancy and Delivery.  Kline-Fath, B. & Bitters, C. (2007) “Prenatal Imaging” Newborn and Infant Nursing Reviews, Vol.7, No. 4.  Mattson, S. & Smith, J.E., (2011) 4th edition Core Curriculum for Maternal-Newborn Nursing.  Queenan, J.T., Hobbins, J. C., & Spong, C. Y. (2005) 4th edition, Protocols for High-Risk Pregnancies

Notas del editor

  1. Several sites are utilized in aspiration. Can be done earlier than anmio
  2. Triple screen: maternal serum alpha fetoprotein (MSAFP), beta hCG, uncongigated estriol Quad Screen: above plus pregnancy associated plasma A protein Need to be aware of maternal weight, gestational age, multiple gestation, race and diabetes – all these can skew results
  3. Many studies, none to find side effects to fetus
  4. Done with U/S
  5. For ABO incompatibilities or hydrops, can tell amt of bilirubin in amniotic fluid to see if fetus needs transfusion
  6. Isoimmunization(mom antibodies attack fetal RBC), parvo virus (slows production of RBC), fetal maternal hemorrhage
  7. Graph is little blurry but shows how much blood to transfuse.
  8. Maternal symptoms: difficulty breathing, uterine contractions
  9. Magnetic resonance imaging Able to separate maternal and fetal tissue, clearer image Claustrophobia, size of abd and fitting in chamber
  10. Due to organ formation
  11. Watch language with pt – tazer, buzzer, zapper VAS programmed for this time, push button till stops Decels common Do not use if fetus compromised or has heart issues