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Duchenne Muscular Dystrophy ,[object Object],By: Tanner Evans & Christa Whoric,[object Object]
What is the disease?,[object Object],Duchenne Muscular Dystrophy is a disease that weakens the muscles in your body rapidly. It is caused by a lack of dystrophin, a protein. ,[object Object],Dystrophin helps keep the muscle cells intact.,[object Object]
How is the disease inherited?,[object Object],GirlsBoys,[object Object],XX              XY,[object Object],The disease is inherited through the X-linked recessive gene. ,[object Object],Only the X gene is affected. ,[object Object],Mothers can be carriers, but will not get the disease. ,[object Object]
Symptoms,[object Object],-Fatigue,[object Object],-Mental retardation (possible, but does not worsen over time),[object Object],-Muscle weakness,[object Object],	*Begins in legs and pelvis, but also occurs in the arms, neck and,[object Object],	other parts of the body,[object Object],	*Difficulty with motor skills,[object Object],	*Frequent falls,[object Object],	*Rapidly worsening weakness,[object Object],-Progressive difficulty walking,[object Object],	*Ability to walk may be gone by age 12,[object Object],{By age 10, person may need braces for walking. By 12, most patients,[object Object],are confined to a wheelchair},[object Object]
How is the disease tested or diagnosed?,[object Object],The patient will have an increased amount of an enzyme called creatine kinase in their blood.  ,[object Object],Boys who are thought to have Duchenne, will have a muscle biopsy. A muscle biopsy is the sampling of muscle tissue for microscopic examination. ,[object Object],Another way of testing this is through electromyography, which is a test that estimates muscle strength and evaluates the nerves that control that muscle. ,[object Object]
Occurrence of Duchenne Muscular Dystrophy ,[object Object],1 out of every 3,600 males ,[object Object],Most common of childhood ,[object Object],muscular dystrophies  ,[object Object],Boys are more at risk for inheriting,[object Object],this disease because of its X-linked gene  ,[object Object]
Treatments ,[object Object],Activity is encouraged because bed rest can ,[object Object],worsen the disease ,[object Object],Physical therapy is helpful to maintain muscle strength and function,[object Object],*Swimming is a good way to ,[object Object],help with this disease,[object Object]
More Info,[object Object],There is no cure for Duchenne Muscular Dystrophy ,[object Object],Boys with this disease will usually not survive past late teens or early adulthood  ,[object Object],Mothers who carry the trait for the disease have a 50/50 chance of passing it on to their son. Mothers alsohave a 50/50 chance of passing the  trait to their daughters.   ,[object Object]
Jesse Davidson,[object Object],Jesse Davidson was born on April 10, 1980. When he was six years old he was diagnosed with Duchenne Muscular dystrophy. When Jesse was 15, John, his father, pushed Jesse 2,050.5 miles across Canada in his wheelchair. His charity is known as Jesse’s Journey. He met the Prime Minister of Canada and Queen ,[object Object],Elizabeth II. His fund raised over 3 million dollars towards research. He died on November 6, 2009.,[object Object]
www.nlm.nih.gov,[object Object],http://depts.washington.edu,[object Object],www.muscular-dystrophy.org,[object Object]

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Duchenne Muscular Dystrophy

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