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Local analgesia in animals_ Dr. Awad Rizk
1. Presented by Dr. Awad Rizk (Mvsc, Ph.D-Tiho-Hannover,Germany) 03.11.2011
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9. + + - - + + -- - - + + + + - - Na + + + + + - - - - Resting (Closed**) Open (brief) inactivated Very slow repolarization in presence of LA LA receptor LA have highest affinity for the inactivated form Refractory period **Closed state may exist in various forms as it moves from resting to open. LA have a high affinity for the different closed forms and may prevent them from opening.
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66. The inverted red L is the site of inverted L block and the green line is the site of linear infiltration for rumenotomy