This presentation discusses the epidemiology of nasal polypi

1. Epidemiology of nasal polyp Dr T Balasubramanian

3. Still lots of questions remains unanswered

4. It could best be described as a clinical manifestation of co existing multiple immunologic pathways

6. Links between nasal polyp and allergic rhinitis is rather weak

7. There is a strong association between asthma & nasal polyp

8. The incidence increases with age

9. Incidence of aspirin hypersensitivity in patients with nasal polyp is high

11. Nasal polypi in children – Cystic fibrosis to be ruled out

12. AFRS is commonly associated with nasal polyposis

14. Chronic rhinosinusitis with nasal polypi

16. TH1 lymphocytes are potent inducers of inflammation

17. If antrochoanal polyp is present should be differentiated from bilateral ethmoidal polypi

19. This type of inflammation is seen in patients with bronchial asthma

21. Both these responses should be optimal to enable the body to get rid of infection

22. Disease tends to occur when either of them predomonates over the other

24. Cytokines secreted by T helper cells type II are anti-inflammatory cytokines. These cytokines are seen during allergic response

26. General atopic status

27. Bronchial asthma

29. Incidence of nasal polypi is 4 times more in patients with asthma

30. Incidence of atopy was more in patients with nasal polypi than in normal population

31. AFRS is commonly associated with nasal polypi

33. CT scan findings – Inspissated secretions with calcification

34. Eosinophilic nasal secretions with the presence of Charcot Leyden crystals

35. Positive isolation of fungal material from sinus contents

36. Thankyou