7. Clinical presentations of pancreatic endocrine tumor Name ( synonym ) Hormone responsible Clinical symptoms Principle of Medical Treatment Insulinoma (insulin-producing tumor) or Beta cell tumor Insulin Whipple triad - Mental confuse, weakness,fatigue and convulsion , palpitation - Fasting hypoglycemia - Relief of hypoglycemic symptoms after glucose administation May require immediate potassium replasement and glucose administration
8. Clinical presentations of pancreatic endocrine tumor Name ( synonym ) Hormone responsible Clinical symptoms Principle of Medical Treatment Gastrinoma (gastrin-producing tumor; ulcerogenic tumor) or G-cell tumors Gastrin Zollinger-Ellison syndrome * Severe gastrointestinal ulcerative disease * Gastric acid hypersecretion * Steatorrhea (fatty diarrhea) 1 . Stabilize hemodynamic and control bleeding from gastrointestinal ulcers 2 . Establish a nonacidic gastric pH with the use of proton pump inhibitors, eg, omeprazole 3 . Administration of the somatostatin analogue octreotide or chemotherapeutic agent