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              Type 2 Diabetes Mellitus    Iris Thiele Isip Tan MD, MSc,
                                          FPCP, FPSEM
               in the Transition Period   Chief, Medical Informatics Unit
          from Childhood to Adulthood     Assoc. Professor 4, UPCM

Saturday, August 4, 12
Peters et al. Diabetes Care for Emerging Adults:
              Recommendations for Transition from
         Pediatric to Adult Diabetes Care Systems.     Reference
                   Diabetes Care Nov 2011;34:2477-85
Saturday, August 4, 12
http://www.flickr.com/photos/dullhunk/3389581452/




                                                Diabetes transition care



                                                                Peters et al. Diabetes Care for Emerging Adults: Recommendations for
                                                        Transition from Pediatric to Adult Diabetes Care Systems. Diabetes Care 2011




           Dearth of empirical evidence                                                Challenges in the
                   on best approaches                                                  transition
Saturday, August 4, 12
http://www.flickr.com/photos/pasukaru76/4320261170/




                         Fundamental differences
                                                     Challenges in the
                            in pediatric and adult
                                                     transition
                            health care providers            Peters et al. Diabetes Care 2011
Saturday, August 4, 12
http://www.flickr.com/photos/jurvetson/3031088430/




     Lack of well-defined criteria to                Challenges in the
     determine transition readiness                 transition
                                                            Peters et al. Diabetes Care 2011
Saturday, August 4, 12
https://www.facebook.com/AlodiaGosiengfiao




                 Changing social and
                                            Challenges in the
           demographic characteristics
                                            transition
                      of young adults               Peters et al. Diabetes Care 2011
Saturday, August 4, 12
http://www.flickr.com/photos/hawee/3527878000/




          Differences in learning styles    Challenges in the
                in the transition period   transition
                                                      Peters et al. Diabetes Care 2011
Saturday, August 4, 12
http://www.flickr.com/photos/andresrueda/3454095552/




             Deficiencies in training
                                                      Challenges in the
                 in care delivery for
                                                      transition
       emerging adults with diabetes                          Peters et al. Diabetes Care 2011
Saturday, August 4, 12
Approaches
             Issues




                            Recommendations
Saturday, August 4, 12
Issues




Saturday, August 4, 12
http://www.sxc.hu/photo/1285834




                           Differences between
                                                    Issues
                         pediatric and adult care
                                                         Peters et al. Diabetes Care 2011
Saturday, August 4, 12
http://www.flickr.com/photos/aldenchadwick/4293213857/




                     Poor control of glycemia
                                                         Issues
                       and other risk factors
                                                              Peters et al. Diabetes Care 2011
Saturday, August 4, 12
NNHES: 56% of adults achieved A1c <7%




                                                          http://www.sxc.hu/photo/1215912



         Only 32% of youth with T1DM
       aged 13-18 y and 18% of those       SEARCH for diabetes in Youth
                                           Study. J Pediatr 2009;155:688-672
      aged >19 y achieved ADA targets
Saturday, August 4, 12
Greatest proportion of youth with T1DM or T2DM
                   in poor glycemic control were teenagers




                                                        http://www.sxc.hu/photo/1066055




            One of every 4 patients     SEARCH for diabetes in Youth
         aged >12 y had A1c >9.5%       Study. J Pediatr 2009;155:688-672

Saturday, August 4, 12
⬆ hypertension and dyslipidemia
                                                               related to obesity




                                                                        http://www.sxc.hu/photo/718085




         ⬆Prevalence of CV risk factors               SEARCH for diabetes in Youth
                         in youth with T2DM vs T1DM   Study. Diabetes Care 2006;29:1891-96

Saturday, August 4, 12
http://www.flickr.com/photos/78428166@N00/4296824658/



          Fatty liver disease is more   SEARCH for diabetes in Youth
     common among obese children        case-control study. Diabetes Care
                                        2009;32:416-20
 with insulin resistance and diabetes
Saturday, August 4, 12
http://www.sxc.hu/photo/544230




                         Loss to follow-up   Issues
                                                      Peters et al. Diabetes Care 2011
Saturday, August 4, 12
http://www.sxc.hu/photo/65898




                                   Increased risk
                         for acute complications
                                                    Issues
                                                             Peters et al. Diabetes Care 2011
Saturday, August 4, 12
http://www.sxc.hu/photo/1159994




                         Psychosocial Issues   Issues
                                                        Peters et al. Diabetes Care 2011
Saturday, August 4, 12
http://www.sxc.hu/photo/550152




    Anxiety disorders can complicate
         self-management of diabetes   Psychosocial Issues
                                                  Peters et al. Diabetes Care 2011
Saturday, August 4, 12
Depressive symptoms in DM

                                                  15-33% of adolescents
                                                      (including 18 to 20 year-olds)

                                                     23-35% of emerging
                                                           adults (18-28 y)

                                                       Clinically significant
                                                     symptoms in 20% of
                                                 older adolescent females

                                                                 http://www.sxc.hu/photo/747912




                    Depression is a well-known
                           comorbid condition.     Psychosocial Issues
                                                              Peters et al. Diabetes Care 2011
Saturday, August 4, 12
Poor metabolic control
                           Reduced adherence


                                                    ⬆risk of DKA
                             ⬆risk of microvascular complications

                           Adolescent and
         postadolescent women with DM       Psychosocial Issues
             at risk for eating disorders           Peters et al. Diabetes Care 2011
Saturday, August 4, 12
16% of teens aged 13-19 y
                                                  with DM reported
                                           using birth control vs
                                                      67% of those
                                                ever sexually active


                                                 Fewer than 1 in 4
                                                    young women
                                            aged 16-20 y aware of
                                              risks of pregnancy



                             Sexual and
               reproductive health issues
                                            Issues
                                                     Peters et al. Diabetes Care 2011
Saturday, August 4, 12
Alcohol use worsens
   glycemic control




   Smoking ⬆CV risk
   and risk for
   microalbuminuria

                         Alcohol, smoking and
                                   drug abuse
                                                Issues
                                                         Peters et al. Diabetes Care 2011
Saturday, August 4, 12
Microalbuminuria in teens:
 10% T1DM and 30% T2DM
                                 Neuropathy in 20% of
                                  adolescents with DM

   Emergence of signs of chronic
         diabetes complications
                                 Issues
                                          Peters et al. Diabetes Care 2011
Saturday, August 4, 12
Approaches
             Issues




                            Recommendations
Saturday, August 4, 12
Approaches




Saturday, August 4, 12
http://www.flickr.com/photos/53370644@N06/4976497160/




                  Fragmented
                 follow-up care


                                                        Poorer glycemic
                                                        control & ⬆ rate
                                                        of hospitalization



         Gaps in follow-up care with a                 Easing the transfer
    decrease in MD visits after transfer               process
                                                               Peters et al. Diabetes Care 2011
Saturday, August 4, 12
http://www.sxc.hu/photo/1008265




                     Observational studies or   No published RCTS
                      uncontrolled programs
                                                       Peters et al. Diabetes Care 2011
Saturday, August 4, 12
http://www.flickr.com/photos/alancleaver/2661425133/




            Time is a major challenge to
        maintaining contact after transfer
                                                       Peters et al. Diabetes Care 2011
Saturday, August 4, 12
Evening hours or flexible clinics

     Longer visit as the initial
     meeting with the adult provider

     Provision of special clinic times
     exclusively for young adults up
     to age 30 y




                Provide written information re:   Provide medical summary
                transfer process and new MD       to receiving MD
                                                          Peters et al. Diabetes Care 2011
Saturday, August 4, 12
http://www.flickr.com/photos/absorbingman/6035479910/




                     Transfer to an adult clinic or    Models of
                                 different hospital    transition care
Saturday, August 4, 12
http://www.flickr.com/photos/absorbingman/6035479910/




         Transition to a combination of                Models of
       pediatric and adult care providers              transition care
Saturday, August 4, 12
http://www.flickr.com/photos/absorbingman/6035479910/




         Transfer to a young adult clinic              Models of
     within the same pediatric hospital                transition care
Saturday, August 4, 12
Patient navigators
       Care ambassadors




                                                   Models of
                         Transition Coordinators   transition care
Saturday, August 4, 12
Workshops to prepare      Models of
                          the transitioning teen   transition care
Saturday, August 4, 12
Approaches
             Issues




                            Recommendations
Saturday, August 4, 12
Recommendations
Saturday, August 4, 12
Prepare for the transition at least
             one year prior; likely during      ADA Recommendation
                   early adolescent years.
Saturday, August 4, 12
Beyond glucose self-monitoring
                                       and insulin administration

                                 Include scheduling appointments
                                   and ensuring medication supply




        Gradual transfer of diabetes care   ADA Recommendation
             responsibilities to the teen
Saturday, August 4, 12
Inform re: differences between    ADA Recommendation
                    pediatric and adult providers
Saturday, August 4, 12
Active problem list       Summary of past
                                                  glycemic control & DM-
                             Medication list       related comorbidities




                                                    Summary of any
                                                     mental health
                         Assessment of diabetes      problems and
                             self-care skills           referrals



       Pediatric provider should provide
        both the patient and future adult             ADA Recommendation
       care provider a written summary
Saturday, August 4, 12
Provide support and
                          links to resources that    ADA Recommendation
                         could benefit the patient.
Saturday, August 4, 12
http://www.sxc.hu/photo/693790




                           Directory of adult
                                                 ADA Recommendation
                         health care providers
Saturday, August 4, 12
Schedule first
                                              appointment with
                                             adult care provider
                                           within 3-4 months of
                                         the final pediatric visit.



    Empower with resources to help
reconnect to care if lost to follow-up    ADA Recommendation

Saturday, August 4, 12
http://www.sxc.hu/photo/586475



             Emphasize consistent use of
         glucose-lowering medications to   ADA Recommendation
                  prevent complications.
Saturday, August 4, 12
http://www.sxc.hu/photo/318333




                              Evaluate and treat for
                         disordered eating behaviors    ADA Recommendation
                             and affective disorders.
Saturday, August 4, 12
http://www.sxc.hu/photo/214353




    Visits q3 mos if taking insulin and
    q3-6 mos for T2DM not on insulin.     ADA Recommendation

Saturday, August 4, 12
Screen for micro- and
                 macrovascular complications.   ADA Recommendation

Saturday, August 4, 12
http://www.sxc.hu/photo/440697




      Discuss birth control, pregnancy
      planning and risks and prevention      ADA Recommendation
        of sexually transmitted illnesses.
Saturday, August 4, 12
Discuss use of alcohol and
                         drugs, smoking and driving.   ADA Recommendation

Saturday, August 4, 12
Ensure that patients receive ongoing
     primary & preventive health care             ADA Recommendation
        (separate from diabetes specialty care)
Saturday, August 4, 12
Approaches
             Issues




                            Recommendations
Saturday, August 4, 12
Thank You
       @endocrine_witch




Saturday, August 4, 12

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Diabetes Mellitus in the Transition Period: From Childhood to Adulthood

  • 1. http://www.sxc.hu/photo/483163 Type 2 Diabetes Mellitus Iris Thiele Isip Tan MD, MSc, FPCP, FPSEM in the Transition Period Chief, Medical Informatics Unit from Childhood to Adulthood Assoc. Professor 4, UPCM Saturday, August 4, 12
  • 2. Peters et al. Diabetes Care for Emerging Adults: Recommendations for Transition from Pediatric to Adult Diabetes Care Systems. Reference Diabetes Care Nov 2011;34:2477-85 Saturday, August 4, 12
  • 3. http://www.flickr.com/photos/dullhunk/3389581452/ Diabetes transition care Peters et al. Diabetes Care for Emerging Adults: Recommendations for Transition from Pediatric to Adult Diabetes Care Systems. Diabetes Care 2011 Dearth of empirical evidence Challenges in the on best approaches transition Saturday, August 4, 12
  • 4. http://www.flickr.com/photos/pasukaru76/4320261170/ Fundamental differences Challenges in the in pediatric and adult transition health care providers Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 5. http://www.flickr.com/photos/jurvetson/3031088430/ Lack of well-defined criteria to Challenges in the determine transition readiness transition Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 6. https://www.facebook.com/AlodiaGosiengfiao Changing social and Challenges in the demographic characteristics transition of young adults Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 7. http://www.flickr.com/photos/hawee/3527878000/ Differences in learning styles Challenges in the in the transition period transition Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 8. http://www.flickr.com/photos/andresrueda/3454095552/ Deficiencies in training Challenges in the in care delivery for transition emerging adults with diabetes Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 9. Approaches Issues Recommendations Saturday, August 4, 12
  • 11. http://www.sxc.hu/photo/1285834 Differences between Issues pediatric and adult care Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 12. http://www.flickr.com/photos/aldenchadwick/4293213857/ Poor control of glycemia Issues and other risk factors Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 13. NNHES: 56% of adults achieved A1c <7% http://www.sxc.hu/photo/1215912 Only 32% of youth with T1DM aged 13-18 y and 18% of those SEARCH for diabetes in Youth Study. J Pediatr 2009;155:688-672 aged >19 y achieved ADA targets Saturday, August 4, 12
  • 14. Greatest proportion of youth with T1DM or T2DM in poor glycemic control were teenagers http://www.sxc.hu/photo/1066055 One of every 4 patients SEARCH for diabetes in Youth aged >12 y had A1c >9.5% Study. J Pediatr 2009;155:688-672 Saturday, August 4, 12
  • 15. ⬆ hypertension and dyslipidemia related to obesity http://www.sxc.hu/photo/718085 ⬆Prevalence of CV risk factors SEARCH for diabetes in Youth in youth with T2DM vs T1DM Study. Diabetes Care 2006;29:1891-96 Saturday, August 4, 12
  • 16. http://www.flickr.com/photos/78428166@N00/4296824658/ Fatty liver disease is more SEARCH for diabetes in Youth common among obese children case-control study. Diabetes Care 2009;32:416-20 with insulin resistance and diabetes Saturday, August 4, 12
  • 17. http://www.sxc.hu/photo/544230 Loss to follow-up Issues Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 18. http://www.sxc.hu/photo/65898 Increased risk for acute complications Issues Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 19. http://www.sxc.hu/photo/1159994 Psychosocial Issues Issues Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 20. http://www.sxc.hu/photo/550152 Anxiety disorders can complicate self-management of diabetes Psychosocial Issues Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 21. Depressive symptoms in DM 15-33% of adolescents (including 18 to 20 year-olds) 23-35% of emerging adults (18-28 y) Clinically significant symptoms in 20% of older adolescent females http://www.sxc.hu/photo/747912 Depression is a well-known comorbid condition. Psychosocial Issues Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 22. Poor metabolic control Reduced adherence ⬆risk of DKA ⬆risk of microvascular complications Adolescent and postadolescent women with DM Psychosocial Issues at risk for eating disorders Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 23. 16% of teens aged 13-19 y with DM reported using birth control vs 67% of those ever sexually active Fewer than 1 in 4 young women aged 16-20 y aware of risks of pregnancy Sexual and reproductive health issues Issues Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 24. Alcohol use worsens glycemic control Smoking ⬆CV risk and risk for microalbuminuria Alcohol, smoking and drug abuse Issues Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 25. Microalbuminuria in teens: 10% T1DM and 30% T2DM Neuropathy in 20% of adolescents with DM Emergence of signs of chronic diabetes complications Issues Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 26. Approaches Issues Recommendations Saturday, August 4, 12
  • 28. http://www.flickr.com/photos/53370644@N06/4976497160/ Fragmented follow-up care Poorer glycemic control & ⬆ rate of hospitalization Gaps in follow-up care with a Easing the transfer decrease in MD visits after transfer process Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 29. http://www.sxc.hu/photo/1008265 Observational studies or No published RCTS uncontrolled programs Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 30. http://www.flickr.com/photos/alancleaver/2661425133/ Time is a major challenge to maintaining contact after transfer Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 31. Evening hours or flexible clinics Longer visit as the initial meeting with the adult provider Provision of special clinic times exclusively for young adults up to age 30 y Provide written information re: Provide medical summary transfer process and new MD to receiving MD Peters et al. Diabetes Care 2011 Saturday, August 4, 12
  • 32. http://www.flickr.com/photos/absorbingman/6035479910/ Transfer to an adult clinic or Models of different hospital transition care Saturday, August 4, 12
  • 33. http://www.flickr.com/photos/absorbingman/6035479910/ Transition to a combination of Models of pediatric and adult care providers transition care Saturday, August 4, 12
  • 34. http://www.flickr.com/photos/absorbingman/6035479910/ Transfer to a young adult clinic Models of within the same pediatric hospital transition care Saturday, August 4, 12
  • 35. Patient navigators Care ambassadors Models of Transition Coordinators transition care Saturday, August 4, 12
  • 36. Workshops to prepare Models of the transitioning teen transition care Saturday, August 4, 12
  • 37. Approaches Issues Recommendations Saturday, August 4, 12
  • 39. Prepare for the transition at least one year prior; likely during ADA Recommendation early adolescent years. Saturday, August 4, 12
  • 40. Beyond glucose self-monitoring and insulin administration Include scheduling appointments and ensuring medication supply Gradual transfer of diabetes care ADA Recommendation responsibilities to the teen Saturday, August 4, 12
  • 41. Inform re: differences between ADA Recommendation pediatric and adult providers Saturday, August 4, 12
  • 42. Active problem list Summary of past glycemic control & DM- Medication list related comorbidities Summary of any mental health Assessment of diabetes problems and self-care skills referrals Pediatric provider should provide both the patient and future adult ADA Recommendation care provider a written summary Saturday, August 4, 12
  • 43. Provide support and links to resources that ADA Recommendation could benefit the patient. Saturday, August 4, 12
  • 44. http://www.sxc.hu/photo/693790 Directory of adult ADA Recommendation health care providers Saturday, August 4, 12
  • 45. Schedule first appointment with adult care provider within 3-4 months of the final pediatric visit. Empower with resources to help reconnect to care if lost to follow-up ADA Recommendation Saturday, August 4, 12
  • 46. http://www.sxc.hu/photo/586475 Emphasize consistent use of glucose-lowering medications to ADA Recommendation prevent complications. Saturday, August 4, 12
  • 47. http://www.sxc.hu/photo/318333 Evaluate and treat for disordered eating behaviors ADA Recommendation and affective disorders. Saturday, August 4, 12
  • 48. http://www.sxc.hu/photo/214353 Visits q3 mos if taking insulin and q3-6 mos for T2DM not on insulin. ADA Recommendation Saturday, August 4, 12
  • 49. Screen for micro- and macrovascular complications. ADA Recommendation Saturday, August 4, 12
  • 50. http://www.sxc.hu/photo/440697 Discuss birth control, pregnancy planning and risks and prevention ADA Recommendation of sexually transmitted illnesses. Saturday, August 4, 12
  • 51. Discuss use of alcohol and drugs, smoking and driving. ADA Recommendation Saturday, August 4, 12
  • 52. Ensure that patients receive ongoing primary & preventive health care ADA Recommendation (separate from diabetes specialty care) Saturday, August 4, 12
  • 53. Approaches Issues Recommendations Saturday, August 4, 12
  • 54. Thank You @endocrine_witch Saturday, August 4, 12