This document summarizes key findings from research on case management practices that are effective in helping homeless individuals. Three factors that make case management most effective are: 1) developing a persistent, reliable and respectful relationship characterized by intimacy and trust between the case manager and client; 2) ensuring adequate staff skills, support and service system capacity; and 3) providing comprehensive and practical support to increase clients' self-care abilities. Effective case management adopts a developmental approach tailored to individual clients' needs.