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Telemedical Project for Integrative Stroke Care
             in Bavaria, Germany

   Conférence Télémédicine et Télésanté en Europe
                 FIEEC / ASIP Santé
                  Paris, 21.10.2011

                 Dr. Peter Müller-Barna
                    Department of Neurology
                      Klinikum Harlaching
             Städtisches Klinikum München GmbH
Overview


• the need for stroke networks


• TEMPiS: key features


• TEMPiS: quality data


• TEMPiS: outcome analysis


• Summary
Overview


• the need for stroke networks


• TEMPiS: key features


• TEMPiS: quality data


• TEMPiS: outcome analysis


• Summary
Burden of Stroke



Strokes in Germany:
• 260.000 strokes every year
• #3 for death:
  40% of the stroke patients die within 1 year
• #1 for disability:
  1 million patients with long-term disability
  caused by stroke
                 Kolominsky-Rabas, Stroke 1998




→ Stroke is a public health challenge of prime importance
Changes in Age Distribution

               2000                           2050




→ Stroke is a public health challenge of prime importance
  with increasing relevance !!!
What to do?

  Stroke unit care                               i.v.-Thrombolysis
  • reduces death or dependency                  increases favourable outcome
    (OR 0.82; 95% CI 0.73 to 0.92; P = 0.001)
                                                 • OTT 0-90 min         NNT 4,5
    NNT = 5                                        (OR 2,55; 95% CI 1,44 to 4,52; P = 0.001)
                                                 • OTT 90-180 min             NNT 9
                                                   (OR 1,64; 95% CI 1,12 to 2,40; P = 0.012)
                                                 • OTT 180-270min             NNT 14
                                                   (OR 1,34; 95% CI 1,06 to 1,68; P = 0.014)




                                                            Time is Brain
                                                            In acute stroke 1.9 million
                                                            neurons die every minute!

                                                  Only a minority of all stroke
                                                  patients in Europe receive
                                                  stroke unit care Leys, Stroke 2007

Cochrane Database of Systematic Reviews 2009                             Lees et al., Lancet 2010
Stroke Units in Bavaria, Germany, in 2002



The need in 2002 was
to improve stroke care
in the underserved
areas of Bavaria.




         Stroke Unit
                                             4
         Stroke Center

        Network-Hospital
Overview


• the need for stroke networks


• TEMPiS: key features


• TEMPiS: quality data


• TEMPiS: outcome analysis


• Summary
Key features of the TEMPiS-Network

Implementation of Stroke        Standard                Training –
  wards in each hospital   treatment protocols   center-based and onsite




Exchange of Experience     Quality Management       Teleconsultations
1. Stroke Wards


Implementation of Stroke Wards
  in each network hospital:
• stroke wards with
  3-6 monitored beds and
  ~ 15 additional beds
• well defined stroke team consisting of:
  doctors, nurses, physiotherapists, ergotherapists,
  speech & swallowing therapists and social workers
• (on site) ward round of a neurologist from Monday
  to Friday
• continuous medical training
• concept of early rehabilitation
2. Standard treatment protocols - SOPs

Our TEMPiS-SOPs form our common basis of
managing stroke:
• TEMPiS-SOPs were developed and are updated
yearly in a cooperative effort
• with statements for doctors,
  nurses and therapists
• we obligate and control network
  hospitals to follow the SOPs
3. Centre based Training

   Stroke classes                      Training days for
                                speech & swallowing therapists




Stroke Update             Sonography            Laryngoscopy
3. Onsite training


                                    Bedside training for nurses
 Regular ward rounds
in each network hospital




                                   Bedside training for therapists
4. Exchange of Experience

Ward rounds & Meetings

                                    Newsletter




    www.tempis.de
5. Quality Management



 Visitation of all network hospitals by the project manager at
  least 3 times per year
 Evaluation of teleconsultations
 benchmarking of the rate of thrombolysis, the door-to-needle-
  time, etc.
 obligatory participation in the German stroke register database
 documentation and analysis of critical incidences
6. Teleconsultation - Network Hospital




           DSL


 Academic Stroke Center
6. Stationary workstation – Stroke Center
6. Teleconsultation – mobile solution




          works with fast UMTS
          = HSDPA (High Speed Downlink Packet Access)
6. Teleconsultations


                 Obligatory indication for a teleconsultation:
                 • onset of symptoms within 4.5 hours
                 • intracranial hemorrhage
                 • impaired consciousness
                 • progressive stroke
                 • brainstem symptoms
                 • NIH-SS  12
                 • stroke patients aged < 60 years



A voluntary teleconsultation is possible whenever requested !
Main capabilities of the TEMPiS-Network


Implementation of Stroke      Standardized              Training –
  wards in each hospital   treatment protocols   center-based and onsite




Exchange of Experience     Quality Management       Teleconsultations




 TEMPiS is based on personal relationship,

 know-how transfer, quality management

 and telemedicine

 ► TEMPiS is a regional network with limited size
Overview


• the need for stroke networks


• TEMPiS: key features


• TEMPiS: quality data


• TEMPiS: outcome analysis


• Summary
number of teleconsultations per year

                                                                                 3.560

                                                          3.216       3.187
                                               3.062
3.000                       2.859   2.837
                2.688




2.000   1.924




1.000




   0

        2003    2004       2005     2006       2007       2008       2009       2010
                                            Source : TEMPiS-database of teleconsultations
admission to CT-scan: less than 60 minutes

100%                2009                    2010                                                                                                          96%
                                                                                                                                                 94%
                                                                                                                                       93%
                                                                                                                           92%
                                                                                                    91%        91%


90%                                                           87%      88%      88%       88%
                                                                                                                                                                       87%
                                         85%       85%


                               81%
                                                                                                                                                                               80%
80%
                    76%




70%       67%




60%




                                                                                                                                                       Bad Tölz
                                                Traunst.




                                                                                                                                                                     TEMPiS
                                                                                                                                                                              BAQ
                                                                              Dachau
                            Ebersb.
                                      Rosenh.
       Eggenf.
                 Mühldorf




                                                                     Pasing




                                                                                                                       Burgl`feld
                                                                                                 Freising




                                                                                                                                    Straubing
                                                                                                            Landshut




                                                                                                                                                Cham
                                                           Kelheim




                                                                                       Zwiesel




                                                                                                                                                                  Source: BAQ
TEMPiS



Teleconsultations
 since 2003 more than 25.000 teleconsultations
 currently ~ 360 per month

Thrombolysis with rt-PA
 since 2003 about 2.300 thrombolysis
 currently ~ 45 per month

~ 6.500 strokes per year in the 15 regional
network hospitals (extra 1.800 strokes in the stroke
centres Harlaching and Regensburg)
tele-stroke units vs. conventional stroke units

                       Todesfälle
                       mortality                TEMPiS-Kooperationskliniken (15)
                   Pneumonierate                BAQ gesamt (80 Kliniken)
              rate of pneumonia
             door toto needletime
              Door needle time
          Frühzeitige Thrombolyse
              early thrombolysis
         Antikoagulation bei in AF
          anticoagulation VHFli
 antiplatelet drugsbei discharge
               TAH at Entlassung
                TAH innerhalb 48h
        antiplatelet drugs at 48h
          carotid Gefäßdiagnostik
                  duplex or CTA
                       Bildgebung
                        CT scan
                      Logopädie
           early speech therapy
   Screening nach for dysphagia
       screening Schluckstörung
                     Mobilisierung
               early mobilisation
      Physiotherpie / Ergotherapie
            early physiotherapy
Information Patient und Angehörige
 information for patient/relatives

                                     0%   20%      40%      60%          80%        100%

                                                           Source: BAQ; analysis for 2010
Overview


• the need for stroke networks


• TEMPiS: key features


• TEMPiS: quality data


• TEMPiS: outcome analysis


• Summary
TEMPiS outcome trial




• Prospectively obtained data of 3122 stroke patients

• Comparing
  Outcome of patients treated in network hospitals
 to
 Outcome of patients treated in control hospitals
• poor Outcome
  dead or
  institutional care or
  at home with severe disability



                                             Lancet Neurol 2006; 5: 742–48
Poor Outcome after 3 Months
           43,0%                          53,4%

-10,4%**

                     At home with
           14,3%                          21%
                    severe disability


           12,5%     Institutional       14,2%
                         Care


           16,2%         Dead            18,1%


           TEMPiS                    Control hospitals
                                            Lancet Neurol 2006; 5: 742–48
overview


• the need for stroke networks


• TEMPiS: key features


• TEMPiS: quality data


• TEMPiS: outcome analysis


• Summary
Take home ...


TEMPiS is a regional network based on personal relationship,

know-how transfer, quality management and telemedicine.



Stroke care within this kind of network improves the prognosis

of stroke patients.



   Telestroke is part of routine stroke care in Bavaria.
Acknowledgement
We thank
► all participating stroke neurologists in the stroke centres
► all TEMPiS hospitals:
  Asklepios Stadtklinik Bad Tölz       Kreiskrankenhaus Kelheim
  Kreisklinik Bad Reichenhall          Kreisklinik Mühldorf
  Asklepios Klinik Burglengenfeld      Klinik München-Pasing
  Kreisklinik Cham                     Klinikum Rosenheim
  Klinikum Dachau                      Klinikum St. Elisabeth Straubing
  Kreisklinik Ebersberg                Klinikum Traunstein
  Kreisklinik Eggenfelden              Krankenhaus Zwiesel
  Klinikum Freising
Thank you for your attention!

         Dr. Peter Müller-Barna
   Consultant - Coordinator of TEMPiS
      Department of Neurology and
         Neurologic Intensive Care
   Städtisches Klinikum München GmbH
            Klinikum Harlaching
    Sanatoriumsplatz 2 - 81545 München
             Tel. 089 6210 2259
E-Mail: peter.mueller-barna@klinikum-muenchen.de


    www.tempis.de

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2011-10-21 ASIP Santé Conférence Télémédecine "Présentation TEMPiS"

  • 1. Telemedical Project for Integrative Stroke Care in Bavaria, Germany Conférence Télémédicine et Télésanté en Europe FIEEC / ASIP Santé Paris, 21.10.2011 Dr. Peter Müller-Barna Department of Neurology Klinikum Harlaching Städtisches Klinikum München GmbH
  • 2. Overview • the need for stroke networks • TEMPiS: key features • TEMPiS: quality data • TEMPiS: outcome analysis • Summary
  • 3. Overview • the need for stroke networks • TEMPiS: key features • TEMPiS: quality data • TEMPiS: outcome analysis • Summary
  • 4. Burden of Stroke Strokes in Germany: • 260.000 strokes every year • #3 for death: 40% of the stroke patients die within 1 year • #1 for disability: 1 million patients with long-term disability caused by stroke Kolominsky-Rabas, Stroke 1998 → Stroke is a public health challenge of prime importance
  • 5. Changes in Age Distribution 2000  2050 → Stroke is a public health challenge of prime importance with increasing relevance !!!
  • 6. What to do? Stroke unit care i.v.-Thrombolysis • reduces death or dependency increases favourable outcome (OR 0.82; 95% CI 0.73 to 0.92; P = 0.001) • OTT 0-90 min NNT 4,5 NNT = 5 (OR 2,55; 95% CI 1,44 to 4,52; P = 0.001) • OTT 90-180 min NNT 9 (OR 1,64; 95% CI 1,12 to 2,40; P = 0.012) • OTT 180-270min NNT 14 (OR 1,34; 95% CI 1,06 to 1,68; P = 0.014) Time is Brain In acute stroke 1.9 million neurons die every minute! Only a minority of all stroke patients in Europe receive stroke unit care Leys, Stroke 2007 Cochrane Database of Systematic Reviews 2009 Lees et al., Lancet 2010
  • 7. Stroke Units in Bavaria, Germany, in 2002 The need in 2002 was to improve stroke care in the underserved areas of Bavaria. Stroke Unit 4 Stroke Center Network-Hospital
  • 8. Overview • the need for stroke networks • TEMPiS: key features • TEMPiS: quality data • TEMPiS: outcome analysis • Summary
  • 9. Key features of the TEMPiS-Network Implementation of Stroke Standard Training – wards in each hospital treatment protocols center-based and onsite Exchange of Experience Quality Management Teleconsultations
  • 10. 1. Stroke Wards Implementation of Stroke Wards in each network hospital: • stroke wards with 3-6 monitored beds and ~ 15 additional beds • well defined stroke team consisting of: doctors, nurses, physiotherapists, ergotherapists, speech & swallowing therapists and social workers • (on site) ward round of a neurologist from Monday to Friday • continuous medical training • concept of early rehabilitation
  • 11. 2. Standard treatment protocols - SOPs Our TEMPiS-SOPs form our common basis of managing stroke: • TEMPiS-SOPs were developed and are updated yearly in a cooperative effort • with statements for doctors, nurses and therapists • we obligate and control network hospitals to follow the SOPs
  • 12. 3. Centre based Training Stroke classes Training days for speech & swallowing therapists Stroke Update Sonography Laryngoscopy
  • 13. 3. Onsite training Bedside training for nurses Regular ward rounds in each network hospital Bedside training for therapists
  • 14. 4. Exchange of Experience Ward rounds & Meetings Newsletter www.tempis.de
  • 15. 5. Quality Management  Visitation of all network hospitals by the project manager at least 3 times per year  Evaluation of teleconsultations  benchmarking of the rate of thrombolysis, the door-to-needle- time, etc.  obligatory participation in the German stroke register database  documentation and analysis of critical incidences
  • 16. 6. Teleconsultation - Network Hospital DSL Academic Stroke Center
  • 17. 6. Stationary workstation – Stroke Center
  • 18. 6. Teleconsultation – mobile solution works with fast UMTS = HSDPA (High Speed Downlink Packet Access)
  • 19. 6. Teleconsultations Obligatory indication for a teleconsultation: • onset of symptoms within 4.5 hours • intracranial hemorrhage • impaired consciousness • progressive stroke • brainstem symptoms • NIH-SS  12 • stroke patients aged < 60 years A voluntary teleconsultation is possible whenever requested !
  • 20. Main capabilities of the TEMPiS-Network Implementation of Stroke Standardized Training – wards in each hospital treatment protocols center-based and onsite Exchange of Experience Quality Management Teleconsultations TEMPiS is based on personal relationship, know-how transfer, quality management and telemedicine ► TEMPiS is a regional network with limited size
  • 21. Overview • the need for stroke networks • TEMPiS: key features • TEMPiS: quality data • TEMPiS: outcome analysis • Summary
  • 22. number of teleconsultations per year 3.560 3.216 3.187 3.062 3.000 2.859 2.837 2.688 2.000 1.924 1.000 0 2003 2004 2005 2006 2007 2008 2009 2010 Source : TEMPiS-database of teleconsultations
  • 23. admission to CT-scan: less than 60 minutes 100% 2009 2010 96% 94% 93% 92% 91% 91% 90% 87% 88% 88% 88% 87% 85% 85% 81% 80% 80% 76% 70% 67% 60% Bad Tölz Traunst. TEMPiS BAQ Dachau Ebersb. Rosenh. Eggenf. Mühldorf Pasing Burgl`feld Freising Straubing Landshut Cham Kelheim Zwiesel Source: BAQ
  • 24. TEMPiS Teleconsultations  since 2003 more than 25.000 teleconsultations  currently ~ 360 per month Thrombolysis with rt-PA  since 2003 about 2.300 thrombolysis  currently ~ 45 per month ~ 6.500 strokes per year in the 15 regional network hospitals (extra 1.800 strokes in the stroke centres Harlaching and Regensburg)
  • 25. tele-stroke units vs. conventional stroke units Todesfälle mortality TEMPiS-Kooperationskliniken (15) Pneumonierate BAQ gesamt (80 Kliniken) rate of pneumonia door toto needletime Door needle time Frühzeitige Thrombolyse early thrombolysis Antikoagulation bei in AF anticoagulation VHFli antiplatelet drugsbei discharge TAH at Entlassung TAH innerhalb 48h antiplatelet drugs at 48h carotid Gefäßdiagnostik duplex or CTA Bildgebung CT scan Logopädie early speech therapy Screening nach for dysphagia screening Schluckstörung Mobilisierung early mobilisation Physiotherpie / Ergotherapie early physiotherapy Information Patient und Angehörige information for patient/relatives 0% 20% 40% 60% 80% 100% Source: BAQ; analysis for 2010
  • 26. Overview • the need for stroke networks • TEMPiS: key features • TEMPiS: quality data • TEMPiS: outcome analysis • Summary
  • 27. TEMPiS outcome trial • Prospectively obtained data of 3122 stroke patients • Comparing Outcome of patients treated in network hospitals to Outcome of patients treated in control hospitals • poor Outcome dead or institutional care or at home with severe disability Lancet Neurol 2006; 5: 742–48
  • 28. Poor Outcome after 3 Months 43,0% 53,4% -10,4%** At home with 14,3% 21% severe disability 12,5% Institutional 14,2% Care 16,2% Dead 18,1% TEMPiS Control hospitals Lancet Neurol 2006; 5: 742–48
  • 29. overview • the need for stroke networks • TEMPiS: key features • TEMPiS: quality data • TEMPiS: outcome analysis • Summary
  • 30. Take home ... TEMPiS is a regional network based on personal relationship, know-how transfer, quality management and telemedicine. Stroke care within this kind of network improves the prognosis of stroke patients. Telestroke is part of routine stroke care in Bavaria.
  • 31. Acknowledgement We thank ► all participating stroke neurologists in the stroke centres ► all TEMPiS hospitals: Asklepios Stadtklinik Bad Tölz Kreiskrankenhaus Kelheim Kreisklinik Bad Reichenhall Kreisklinik Mühldorf Asklepios Klinik Burglengenfeld Klinik München-Pasing Kreisklinik Cham Klinikum Rosenheim Klinikum Dachau Klinikum St. Elisabeth Straubing Kreisklinik Ebersberg Klinikum Traunstein Kreisklinik Eggenfelden Krankenhaus Zwiesel Klinikum Freising
  • 32. Thank you for your attention! Dr. Peter Müller-Barna Consultant - Coordinator of TEMPiS Department of Neurology and Neurologic Intensive Care Städtisches Klinikum München GmbH Klinikum Harlaching Sanatoriumsplatz 2 - 81545 München Tel. 089 6210 2259 E-Mail: peter.mueller-barna@klinikum-muenchen.de www.tempis.de