1. Dr. Scheele’s New Book:
The Obesity Cure
George A. Scheele, M.D.
Roadmap to Metabolic Health and
Sustained Weight Control with
Power Amino Acids®

2. Meet Dr. Scheele
Dr. George A. Scheele, Creator of Factor4
Weight Control®, to combat obesity and
metabolic disease:
• Board Certified in Internal Medicine
• Princeton BA & John Hopkins MD
• Professor at Rockefeller University, Yale
University School of Medicine and Harvard
Medical School.
• Two time Nobel Associate (1974 & 1999)
• First to figure out how to separate all the
proteins in the human body (est. 20,000) by
inventing 2D gel electrophoresis
“As a medical doctor with over 30 years of
research, my personal mission is to reduce
worldwide obesity and metabolic disease. That is
why I created Factor4 Weight Control®.”
– George A. Scheele, MD

3. The Obesity Cure
Book Purpose:
Call Attention to The Obesity Epidemic
Since 1980:
• Adult obesity has doubled (2x)
• Childhood obesity has tripled (3x)
• Morbid obesity has sextupled (6x)
Resolve the Long-Standing Diet Wars
• High protein/fat diets of Atkins
• Low fat diets of national policy
Provide a New Approach to Weight-Loss Health
AIM: To Resolve the Obesity Epidemic

4. Solid Scientific Research
Estimated $50 Billion of NIH Support Over 50 Years in
Digestive and Metabolic Health:
The Basic Science
The Cure
The Obesity Cure Connects the Dots
For the Clinical Breakthrough

5. Dietary Causes of Obesity
Contributory Factors:
• Excess calories in a sedentary society
• Excess saturated & trans fat
• Excess salt
Root Causes:
• Excess refined sugars & carbohydrates
• Protein Deficiency Syndrome – New!
Weight Loss Paradox Explained

6. Sugar is Addictive
Hallmarks of Sugar Addiction:
• Dependency
• Cravings
• Withdrawal symptoms
• Yo-Yo metabolism (3 meals & 3-4 snacks per day)
Hallmarks of Sugar Pathology
• Increased levels of sugar & insulin in blood
• Insulin resistance to protect cells
• High blood insulin levels shut off fat metabolism
• Forever high insulin levels: Fat Forever!
The Modern American Diet (MAD)

7. Sugar Consumption Increased
Mayor Bloomberg displays
the amount of sugar
contained in soda drinks
In Higher Dosage Sugar is Toxic:
• Over the past 100 years daily sugar consumption has increased more than
10-fold, (from 2 to 22 teaspoons per day)
• Sugar soda drinks have increased in size from 8 oz to 12 oz to 20 oz to 64 oz
• HFCS is responsible for increasing obesity rates in America since 1980
• HFCS & sugar show multiple toxic effects at high concentrations:
 Glycation of proteins lead to cross-linked proteins called Advanced
Glycation Endproducts (AGEs)
 The immune system seeks to destroy these foreign-looking bodies
 Resulting inflammation leads to endothelial plaques and arteriosclerosis
• In 2011 two fifteen year old girls required liver transplants in UCSF for fatty liver
resulting in cirrhosis
Sugar: Pure, White & Deadly

8. Sugar Addiction
The Perfect Storm:
• Consumers addicted to HFCS
• Food Industry addicted to profits
• Farmers addicted to government subsidies to
grow corn ($3.5 billion a year)
Sugar Leads to Fat Stored in 3 Places
• Fat depots throughout the body
• Fat in the Liver
• Fatty plaques throughout the arterial system
Result: Worldwide Obesity & Metabolic Disease

9. Selective Protein Deficiency Syndrome
High Carb Diets Cause Protein Deficiency
2-Dimensional Gel Analysis:
A: Health
Normal Protein Pattern
Normal body weight
B: Selective Protein Deficiency Syndrome
Positive Charged Proteins Reduced by 90%
Within 12 days (gain in body weight)
C: CORRECTION with Factor4 Weight Control®
Power Amino Acids® correct protein deficiency
(Body weight returns to normal)
Maintain Your Protein Team To Burn Fat

10. Power Amino Acids
Free Amino Acids Absorbed Early (10-90 minutes):
• Essential amino acids
• Positive-charged amino acids
• Satiety amino acids
Protein-Bound Amino Acids Absorbed Later (1-4 hours)
• Essential amino acids (9)
• Non-essential amino acids (11)
Plus: Amino Acids Enhance Protein Nutrition
• Power Amino Acids increase protein digestion
& Amino acid absorption 6-fold
Early, Sustained & Enhanced Nutrition

11. The Solution
Power Amino Acids® Correct All Dietary
Causes of Obesity:
• Curb appetite for refined sugars, processed
carbs, and fat
• Satisfy hunger with minimal calories
• Correct deficiencies in positive-charged
amino acids, proteins & metabolic pathways
to optimize fat metabolism
A Weight Loss Strategy That Works!

12. Bottom Line
Scientific Research Reveals a New & Better Approach
to Weight Control and Metabolic Health:
Power Amino Acids®
Exploit nature’s feedback mechanisms to:
• Suppress appetite to avoid food cravings
• Burn fat to reduce excess body weight
• Build muscle to improve body definition
• Boost energy to tackle life
Power Amino Acids® Essential for Weight Control!

13. The Product
* Claims have not been reviewed by the FDA
Health & Wellness Innovation at its Best

14. Timeline of Weight Loss Success
• “Sweet tooth” lost within the first few days
• Appetite suppression (comfort, satisfaction and well-being)
recognized within a few days
• Body rebuilt with pep, energy, activity, stamina &
endurance during the first month
• Body fat begins to decrease in the first week but initially
offset by increase in muscle mass
• Clothes fit better within weeks
• Body scale weight begins to decline shortly thereafter
• Weight loss adjusts when normal body weight achieved
Just a Matter of Time
Before You Meet Your Weight Loss Goals!

15. F4 Shake & Smoothie Strategies
Daily Routine for Weight Loss Strategies:
• 3 to 4 shakes per day to optimize weight loss:
 Meal replacement strategy for breakfast (smoothie)
 Portion control for lunch (Half lunch with shake)
 Snack control (shakes in lieu of snacks, particularly at night)
• Normal dinner with protein source & 2 vegetables
• Replace sugar drinks with Factor4 shakes
• Lose 5 to 10 pounds per month
• Some lose 10 to 20 pounds per month
Maintenance Strategy:
• 2 shakes per day to sustain weight control
Bon Voyage to Good Health

16. Optimize Weight Loss Health
Four Simple Tips to Normalize Weight:
• Avoid sugar, processed carbs and excess salt
• Boycott cellophane foods made by the Food
Industry
• Boycott HFCS drinks made by the beverage
industry (soft drinks, energy drinks, fruit juices)
• Drink Factor4 shakes to tame appetite, satisfy
cravings, boost energy, normalize body weight,
and ensure nutritional health
Your Weight Loss Goals Achieved!

17. Weight Loss Study
Conducted in 2007:
• History: 25 subjects with Chronic overweight
disorders for 20-30 yrs. (historical controls)
• Within 3 months 96% of subjects lost weight
• Weight loss results:
Endpoints 3 months 6 months 12 months
Weight loss in 8.4 lbs 16.2 lbs 33.4 lbs
pounds
% body weight 4.5% 8.2% 16%
loss
Weight Loss Significance:
FDA Requires a 5% Loss in Body Weight in 12 Months

18. Weight Loss Performance
Factor4™ Outperforms Popular Diet Plans:
Diet Plan Weight Loss
Factor4 Weight 33 lbs
Control®1
Factor4 Weight 16 lbs
Control®2
Atkins3 10 lbs
National 6 lbs
Guidelines3
Dean Ornish3 5 lbs
Zone3 3.5 lbs
112 month results 26 month results 312month results
NovaLife NovaLife JAMA, March, 2007

19. Obesity & Metabolic Syndrome
Overweight Disorders are Part of the
Metabolic Syndrome:
• Selective protein deficiency leads to a wide variety of
chronic degenerative disease
• Overweight disorders & obesity exist in a spectrum of
metabolic diseases associated with Metabolic Syndrome
• Includes chronic degenerative diseases that are
responsible for accelerated aging and early death
• Obesity is the most obvious manifestation of Metabolic
Syndrome
Two Epidemics: Obesity & Metabolic Disease

20. Epidemic of Metabolic Disease
Number of Cases in the US alone:
Disease Incidence
Overweight disorders 150 million
Obesity 75 million
High blood pressure 34 million
High cholesterol & TGL 30 million
High blood sugar 90 million
Type 2 Diabetes 30 million
Cardiovascular disease 57 million
Autoimmune disease 50 million
Cancer 18 million
Osteoarthritis 20 million
Gallstones 19 million
America Challenged with Chronic Degenerative Disease!

21. The Conclusion
Bon Voyage to Normal Body Weight,
Metabolic Health, and Anti-Aging Health
with
Power Shakes & Smoothies
Containing Power Amino Acids®
www.factor4health.com
Look Younger, Live Longer & Feel Better
With Power Amino Acids®

22. The Scientific Evidence
Power Amino Acids®:
• Suppress appetite centers in brain & stomach
• Correct the food-chain deficiencies in essential and
positive-charged amino acids
• Close the food chain gap to increase metabolism
• Rebalance protein health between positive-
charged and negative-charged proteins (selective
protein deficiency syndrome corrected)
• Reset metabolic pathways to burn fat
Power Amino Acids® Stimulate
Weight Loss and Sustained Weight Control