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How megatrends are affecting the pharma
       industry, and how the CI function can use
      megatrends to increase its strategic relevance




Frederic De Meyer
Senior CI Investigator
I.S.I.S. – Integrated Strategic Information Services, Inc. – www.isisglobal.com
Office Switzerland: +41.41.455.2522


                                              www.isisglobal.com
Aim of this presentation


 Raising awareness of the multitude of trends
  affecting the pharma business, either directly or
  indirectly
 Learn how to use these insights to increase the CI
  function to the highest strategic level within your
  company




                        www.isisglobal.com
let’s start with a challenge:
what do these have in common?




            www.isisglobal.com
here’s a hint…




                            In 2002 Barbie lost its      Until 2006 Coca Cola
Ford almost got out of      market predominance             was boycotted           GM’s Hummer saw
 business in the early       to a new competitor         multiple times in India   sales drop 85% from
1900’s for sticking to it    who just entered this         due to its water            2006 to 2009
standardized products          market the year             mismanagement
                                    before                      practices




                                             www.isisglobal.com
sometimes long-term shifts can
have short-term consequences!




            www.isisglobal.com
before we start… what are megatrends
exactly?

           one hurricane is not a trend, it’s an event...



           an increasing number of hurricanes in the US
           is a trend, not necessarily a megatrend



           a worldwide increase in number and intensity of
           hurricanes would be a megatrend



           and the consequences might trigger new
           (mega)trends



                         www.isisglobal.com
Outline

• …a brain teaser as a starter
• Long-term trends affecting the pharma industry in
  the coming decade
   • The most obvious ones…
   • Trends currently forming, outcome uncertain
   • Some speculation…
• How to use these insights to increase the strategic
  relevancy of the CI function in your company
   • Setting up a megatrend exercise within your company
   • Using megatrends to assess your competitive positioning
     for the long run



                          www.isisglobal.com
we currently track +40 megatrends closely

    DEMOGRAPHIC                       TECHNOLOGY                         GEOPOLITICS
• aging population              • ubiquitous computing             • power shift to East
• increasing world population   • disintermediation                • globalization 3.0
• genY/Milennials               • crowdsourcing                    • trade blocs and unions
• urbanization/geographic       • social Media                     • rising middle class
mobility                        • augmented Reality                • the Market State
• multi-ethnic society          • SaaS, DIY
• gap rich-poor                 • cloud Computing
                                • 3D                                   SUSTAINABILITY
                                • enhanced humans                  • global warming
                                                                   • scarcity of resources
   BUSINESS TRENDS                                                 • energy dependency
                                                                   • biodiversity
• shared value (CSR)                                               • green technologies
• social Entrepreneurship
                                          SOCIETY
• social Business               • dematerialization
• open source/ innovation       (digitization)                            CONSUMER
• decentralization              • talent shortage                  • mass customization
• gamification                  • boundary blurring                • radical transparency
• virtualization                • have’s and have not’s (digital   • social buying
• disruptive business models    divide)                            • sustainable/ethical buying


                                          www.isisglobal.com
…but not all of them are relevant for pharma



Trends with an obvious     Early signs of times to        Somewhat more
        impact                     come?                   speculative…

• aging population         • informed patients         • market State
• climate change           • customization             • enhanced humans (GRIN,
• global mobility          • open source pharma        genetic engineering,
• new migration patterns   • DIY health                bioprinting, …)
• urbanization             • shared value
                           • health ‘as a service’




                                  www.isisglobal.com
…let’s start with the ones that we can clearly see, but
      from which the full extent is yet unknown



 Trends with an obvious     Early signs of times to        Somewhat more
         impact                     come?                   speculative…

 • Aging population         • informed patients         • Market State
 • Climate change           • customization             • Enhanced humans
 • Global mobility          • open source pharma
 • new migration patterns   • DIY health
 • urbanization             • shared value
                            • health ‘as a service’




                                   www.isisglobal.com
the patient has limitless ways to be as
          knowledgeable as the doctor




Do you have a direct touch with the ultimate patient?

                     www.isisglobal.com
(mass) Customization is the new paradigm




   Is this potentially a new source of revenue?

                   www.isisglobal.com
Open source pharma challenges the current
          business R&D model




   Should you embrace or fight this new model?

                   www.isisglobal.com
Shared value and social entrepreneurship can
           unleash new innovations
 Dynamics of changes vs social environment

                                            Social
 Core                                   Entrepreneurs
product               Threat area
                                       Social Innovation



                          Comply
                                         Corporate
peripheral             (legislation,
                                        foundations
                      standards, …)

                       Imposed by             Own
                       community            initiative
(Frederic De Meyer)




    How to combine profitability with social responsibility?

                                               www.isisglobal.com
New market for DIY health
(9000 Apple apps for personal health care)




     is the doctor still your ‘route to market’?

                     www.isisglobal.com
The underlying transformation for Health Care
                  providers
                    institutions




                       TRUST
       reactive                                             pro-active
                               ATTITUDE




                     community
                                          (based on a chart from Across consultancy)




  How do you redefine your position in this new
                  paradigm?
                   www.isisglobal.com
…some speculative trends and their
             consequences for pharma


Trends with an obvious     Early signs of times to        Somewhat more
        impact                     come?                   speculative…

• Aging population         • Informed patients         • Market State
• Climate change           • Customization             • Enhanced humans
• Global mobility          • Open source pharma
• new migration patterns   • DIY health
• urbanization             • Shared value
                           • Health ‘as a service’




                                  www.isisglobal.com
The market state, an imperative or a delusion?




Will government become your key partner in the future?
                      www.isisglobal.com
Human enhancement as an alternative to
              medicine?




Who will be your key partners in the future (technology,
                     insurers, …)?
                       www.isisglobal.com
Are these trends applicable to Europe?




               www.isisglobal.com
Outline

• …a brain teaser as a starter
• Long-term trends affecting the pharma industry in
  the coming decade
   • The most obvious ones…
   • Trends currently forming, outcome uncertain
   • Some speculation…
• How to use these insights to increase the strategic
  relevancy of the CI function in your company
   • Setting up a megatrend exercise within your company
   • Using megatrends to assess your competitive positioning
     for the long run



                          www.isisglobal.com
Where tomorrow’s pharma innovation will
                 come from
•   Aging population
•   Global warming                               •   New ‘go-to-market’
•   Urbanization                                 •   New markets
•   New migration                                •   New customers
                                                 •   New partners
•   DIY Health                                   •   New channels
•   Informed patients                            •   New ways of
•   Open sourcing                                    influencing patients
•   Shared value                                 •   New vision/mission
•   Customization                                •   New organization
•   Health ‘as a service’                        •   New business model
                                                 •   More efficient R&D
•   Market State
•   Enhanced humans                              •   More successful future



      Do you take the lead or do you wait for disruptive
                     models to emerge?
                            www.isisglobal.com
how the CI function could use megatrends
  assessment to increase its impact on
            business strategy




          www.isisglobal.com
here’s a simple process to assess the impact of
megatrends on your company:


                 #1 identify              Mega trends
              Megatrends to discuss



                  #2 discuss Megatrends
                         internally



                   #3draw conclusions
                  and recommendations



              #4 Communicate    results
              internally and externally
but the devil is in the detail…




            www.isisglobal.com
guidelines for selecting trends to assess in your company


                Mega trends
                              •   don’t select (exclusively) trends with
                                  an obvious impact on your industry
                                  or company… the most successful
                                  ideas for innovation will come from
                                  elsewhere;

                              •   get your ideas and selection from a
                                  combination of internal (survey) and
                                  external (consultants) input;

                              •   generate 50 ideas for megatrends,
                                  select 20 to discuss.
guidelines for discussing trends in your company


                           •   Invite people with different
                               background, functions and seniority

                           •   follow a discussion template -for
                               instance Osterwalder’s business
                               model canvas:




                           •   5-6 persons per theme, 30-60 min. per
                               trend;

                           •   also look at anti-trends;

                           •   keep it fun !
guidelines for drawing conclusions from the trends
discussions


                           •   segment the trends so as to show
                               which ones need action or close
                               monitoring




                           •   map the way megatrends impact your
                               customer segments and stakeholders
guidelines for communicating the conclusions of the
megatrends exercise



                          •   Set up different documents dependent
                              on target group and aim:
Outline

• …a brain teaser as a starter
• Long-term trends affecting the pharma industry in
  the coming decade
   • The most obvious ones…
   • Trends currently forming, outcome uncertain
   • Some speculation…
• How to use these insights to increase the strategic
  relevancy of the CI function in your company
   • Setting up a megatrend exercise within your company
   • Using megatrends to assess your competitive positioning
     for the long run



                          www.isisglobal.com
How to assess your long-term competitiveness
        and short-term actions needed



                                        1. List of 25 metrics that
                                           indicate long-term
                                       competitiveness (industry
                                               dependent)



                                       2. Weigh the topic in terms
                                       of importance/relevance to
                                              the industry



                                        3. Do a neutral benchmark
                                       (1-5 scores) based on public
                                             sources and info




                  www.isisglobal.com
How to assess your long-term competitiveness
   and short-term actions needed (cont.)

     Future readiness benchmark company <YOU>
                                                                       4. Draw conclusions, set
                Demographics
                                                                          recommendations


     Strategy                  Sustainability
                                                       YOU
                                                                      In this case:
                                                       Top overall        1. Preparedness for
                                                       performer          geopolitical trends is
 New Business                                          Average of 6        currently your key
                               Consumers
   models                                              companies       competitive differentiator.
                                                                         This needs to be kept!

                 Geopolitics
                                                                      2. Top performer overall has
                                                                        introduced key disruptive
                                                                           business model and
                                                                        customer innovation. You
                                                                      need to study which of these
                                                                       you can leverage profitably
                                                                             for your business


                                        www.isisglobal.com
Overall conclusion

• Investigating long-term trends has short-term relevance:
   » Ideas for innovation
   » Find competitive differentiators
   » Refine strategy for future success
• There is an easy, structured way to get the maximum
  value out of a megatrend exercise;
• By taking the lead of this exercise, the CI function would
  elevate its relevance in the strategic direction of the
  company.




                               www.isisglobal.com
The future can not be predicted…
                          but it can be made !
                                          (ancient African saying)




  prepare your business now, and make sure CI has
                the leading role in it!




Frederic De Meyer, Senior CI Investigator, I.S.I.S.- frederic@isisglobal.com
Marc Limacher, Managing Director, I.S.I.S. – marc@isisglobal.com
Europe (Switzerland): +41.41.455.2522          U.S.: +1.650.298.8555
www.isisglobal.com

               Lucerne – San Francisco – Princeton (NJ) – Shanghai – Bangalore – Miami
                                            www.isisglobal.com

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Using megatrend assessments in pharma in order to raise the relevance of the CI department within your organization

  • 1. How megatrends are affecting the pharma industry, and how the CI function can use megatrends to increase its strategic relevance Frederic De Meyer Senior CI Investigator I.S.I.S. – Integrated Strategic Information Services, Inc. – www.isisglobal.com Office Switzerland: +41.41.455.2522 www.isisglobal.com
  • 2. Aim of this presentation  Raising awareness of the multitude of trends affecting the pharma business, either directly or indirectly  Learn how to use these insights to increase the CI function to the highest strategic level within your company www.isisglobal.com
  • 3. let’s start with a challenge: what do these have in common? www.isisglobal.com
  • 4. here’s a hint… In 2002 Barbie lost its Until 2006 Coca Cola Ford almost got out of market predominance was boycotted GM’s Hummer saw business in the early to a new competitor multiple times in India sales drop 85% from 1900’s for sticking to it who just entered this due to its water 2006 to 2009 standardized products market the year mismanagement before practices www.isisglobal.com
  • 5. sometimes long-term shifts can have short-term consequences! www.isisglobal.com
  • 6. before we start… what are megatrends exactly? one hurricane is not a trend, it’s an event... an increasing number of hurricanes in the US is a trend, not necessarily a megatrend a worldwide increase in number and intensity of hurricanes would be a megatrend and the consequences might trigger new (mega)trends www.isisglobal.com
  • 7. Outline • …a brain teaser as a starter • Long-term trends affecting the pharma industry in the coming decade • The most obvious ones… • Trends currently forming, outcome uncertain • Some speculation… • How to use these insights to increase the strategic relevancy of the CI function in your company • Setting up a megatrend exercise within your company • Using megatrends to assess your competitive positioning for the long run www.isisglobal.com
  • 8. we currently track +40 megatrends closely DEMOGRAPHIC TECHNOLOGY GEOPOLITICS • aging population • ubiquitous computing • power shift to East • increasing world population • disintermediation • globalization 3.0 • genY/Milennials • crowdsourcing • trade blocs and unions • urbanization/geographic • social Media • rising middle class mobility • augmented Reality • the Market State • multi-ethnic society • SaaS, DIY • gap rich-poor • cloud Computing • 3D SUSTAINABILITY • enhanced humans • global warming • scarcity of resources BUSINESS TRENDS • energy dependency • biodiversity • shared value (CSR) • green technologies • social Entrepreneurship SOCIETY • social Business • dematerialization • open source/ innovation (digitization) CONSUMER • decentralization • talent shortage • mass customization • gamification • boundary blurring • radical transparency • virtualization • have’s and have not’s (digital • social buying • disruptive business models divide) • sustainable/ethical buying www.isisglobal.com
  • 9. …but not all of them are relevant for pharma Trends with an obvious Early signs of times to Somewhat more impact come? speculative… • aging population • informed patients • market State • climate change • customization • enhanced humans (GRIN, • global mobility • open source pharma genetic engineering, • new migration patterns • DIY health bioprinting, …) • urbanization • shared value • health ‘as a service’ www.isisglobal.com
  • 10. …let’s start with the ones that we can clearly see, but from which the full extent is yet unknown Trends with an obvious Early signs of times to Somewhat more impact come? speculative… • Aging population • informed patients • Market State • Climate change • customization • Enhanced humans • Global mobility • open source pharma • new migration patterns • DIY health • urbanization • shared value • health ‘as a service’ www.isisglobal.com
  • 11. the patient has limitless ways to be as knowledgeable as the doctor Do you have a direct touch with the ultimate patient? www.isisglobal.com
  • 12. (mass) Customization is the new paradigm Is this potentially a new source of revenue? www.isisglobal.com
  • 13. Open source pharma challenges the current business R&D model Should you embrace or fight this new model? www.isisglobal.com
  • 14. Shared value and social entrepreneurship can unleash new innovations Dynamics of changes vs social environment Social Core Entrepreneurs product Threat area Social Innovation Comply Corporate peripheral (legislation, foundations standards, …) Imposed by Own community initiative (Frederic De Meyer) How to combine profitability with social responsibility? www.isisglobal.com
  • 15. New market for DIY health (9000 Apple apps for personal health care) is the doctor still your ‘route to market’? www.isisglobal.com
  • 16. The underlying transformation for Health Care providers institutions TRUST reactive pro-active ATTITUDE community (based on a chart from Across consultancy) How do you redefine your position in this new paradigm? www.isisglobal.com
  • 17. …some speculative trends and their consequences for pharma Trends with an obvious Early signs of times to Somewhat more impact come? speculative… • Aging population • Informed patients • Market State • Climate change • Customization • Enhanced humans • Global mobility • Open source pharma • new migration patterns • DIY health • urbanization • Shared value • Health ‘as a service’ www.isisglobal.com
  • 18. The market state, an imperative or a delusion? Will government become your key partner in the future? www.isisglobal.com
  • 19. Human enhancement as an alternative to medicine? Who will be your key partners in the future (technology, insurers, …)? www.isisglobal.com
  • 20. Are these trends applicable to Europe? www.isisglobal.com
  • 21. Outline • …a brain teaser as a starter • Long-term trends affecting the pharma industry in the coming decade • The most obvious ones… • Trends currently forming, outcome uncertain • Some speculation… • How to use these insights to increase the strategic relevancy of the CI function in your company • Setting up a megatrend exercise within your company • Using megatrends to assess your competitive positioning for the long run www.isisglobal.com
  • 22. Where tomorrow’s pharma innovation will come from • Aging population • Global warming • New ‘go-to-market’ • Urbanization • New markets • New migration • New customers • New partners • DIY Health • New channels • Informed patients • New ways of • Open sourcing influencing patients • Shared value • New vision/mission • Customization • New organization • Health ‘as a service’ • New business model • More efficient R&D • Market State • Enhanced humans • More successful future Do you take the lead or do you wait for disruptive models to emerge? www.isisglobal.com
  • 23. how the CI function could use megatrends assessment to increase its impact on business strategy www.isisglobal.com
  • 24. here’s a simple process to assess the impact of megatrends on your company: #1 identify Mega trends Megatrends to discuss #2 discuss Megatrends internally #3draw conclusions and recommendations #4 Communicate results internally and externally
  • 25. but the devil is in the detail… www.isisglobal.com
  • 26. guidelines for selecting trends to assess in your company Mega trends • don’t select (exclusively) trends with an obvious impact on your industry or company… the most successful ideas for innovation will come from elsewhere; • get your ideas and selection from a combination of internal (survey) and external (consultants) input; • generate 50 ideas for megatrends, select 20 to discuss.
  • 27. guidelines for discussing trends in your company • Invite people with different background, functions and seniority • follow a discussion template -for instance Osterwalder’s business model canvas: • 5-6 persons per theme, 30-60 min. per trend; • also look at anti-trends; • keep it fun !
  • 28. guidelines for drawing conclusions from the trends discussions • segment the trends so as to show which ones need action or close monitoring • map the way megatrends impact your customer segments and stakeholders
  • 29. guidelines for communicating the conclusions of the megatrends exercise • Set up different documents dependent on target group and aim:
  • 30. Outline • …a brain teaser as a starter • Long-term trends affecting the pharma industry in the coming decade • The most obvious ones… • Trends currently forming, outcome uncertain • Some speculation… • How to use these insights to increase the strategic relevancy of the CI function in your company • Setting up a megatrend exercise within your company • Using megatrends to assess your competitive positioning for the long run www.isisglobal.com
  • 31. How to assess your long-term competitiveness and short-term actions needed 1. List of 25 metrics that indicate long-term competitiveness (industry dependent) 2. Weigh the topic in terms of importance/relevance to the industry 3. Do a neutral benchmark (1-5 scores) based on public sources and info www.isisglobal.com
  • 32. How to assess your long-term competitiveness and short-term actions needed (cont.) Future readiness benchmark company <YOU> 4. Draw conclusions, set Demographics recommendations Strategy Sustainability YOU In this case: Top overall 1. Preparedness for performer geopolitical trends is New Business Average of 6 currently your key Consumers models companies competitive differentiator. This needs to be kept! Geopolitics 2. Top performer overall has introduced key disruptive business model and customer innovation. You need to study which of these you can leverage profitably for your business www.isisglobal.com
  • 33. Overall conclusion • Investigating long-term trends has short-term relevance: » Ideas for innovation » Find competitive differentiators » Refine strategy for future success • There is an easy, structured way to get the maximum value out of a megatrend exercise; • By taking the lead of this exercise, the CI function would elevate its relevance in the strategic direction of the company. www.isisglobal.com
  • 34. The future can not be predicted… but it can be made ! (ancient African saying) prepare your business now, and make sure CI has the leading role in it! Frederic De Meyer, Senior CI Investigator, I.S.I.S.- frederic@isisglobal.com Marc Limacher, Managing Director, I.S.I.S. – marc@isisglobal.com Europe (Switzerland): +41.41.455.2522 U.S.: +1.650.298.8555 www.isisglobal.com Lucerne – San Francisco – Princeton (NJ) – Shanghai – Bangalore – Miami www.isisglobal.com