24. Explain why ATP yield in aerobic cell respiration is so much higher than in anaerobic respiration. (Long answer question – think about knock-on effects of reduced O2). 8 marks<br />Link question:<br />Draw and annotate sketch graphs of the effects of the following variables on rate of respiration – temperature, CoA concentration, pH. <br />Sample exam questions: <br />Practice these in your own time. <br />Describe the role of Acetyl CoA in the metabolism of lipids. (2 marks)<br />Explain chemiosmosis as it occurs in respiration. (2 marks)<br />Explain the process of aerobic respiration, including oxidative phosphorylation (8 marks)<br />Compare aerobic and anaerobic respiration, including yield of ATP. (8 marks)<br />Interesting reading: <br />Nobel prizewinners: Krebs and Lipmann:<br />http://nobelprize.org/nobel_prizes/medicine/laureates/1953/ <br />Sample data analysis question (from IB QuestionBank)<br />At the start of glycolysis, glucose is phosphorylated to produce glucose 6-phosphate, which is converted into fructose 6-phosphate. A second phosphorylation reaction is then carried out, in which fructose 6-phosphate is converted into fructose 1,6-bisphosphate. This reaction is catalyzed by the enzyme phosphofructokinase. <br />80962564198500Biochemists measured the enzyme activity of phosphofructokinase (the rate at which it catalyzed the reaction) at different concentrations of fructose 6-phosphate. The enzyme activity was measured with a low concentration of ATP and a high concentration of ATP in the reaction mixture. The graph below shows the results. <br />(a)(i)Using only the data in the above graph, outline the effect of increasing fructose 6-phosphate concentration on the activity of phosphofructokinase, at a low ATP concentration.<br />...............................................................................................................................<br />...............................................................................................................................<br />...............................................................................................................................<br />(2)<br />(ii)Explain how increases in fructose 6-phosphate concentration affect the activity of the enzyme.<br />...............................................................................................................................<br />........................................................................................................................<br />...............................................................................................................................<br />...............................................................................................................................<br />(2)<br />(b)(i)Outline the effect of increasing the ATP concentration on the activity of phosphofructokinase.<br />...............................................................................................................................<br />...............................................................................................................................<br />...............................................................................................................................<br />...............................................................................................................................<br />(2)<br />(ii)Suggest an advantage to living organisms of the effect of ATP on phosphofructokinase.<br />...............................................................................................................................<br />...............................................................................................................................<br />(1)<br />(Total 7 marks)<br />Works Cited BIBLIOGRAPHY 1. Allott, Andrew. IB Study Guide: Biology for the IB Diploma. s.l. : Oxford University Press, 2007. 978-0-19-915143-1.2. Mindorff, D and Allott, A. Biology Course Companion. Oxford : Oxford University Press, 2007. 978-099151240.3. Clegg, CJ. Biology for the IB Diploma. London : Hodder Murray, 2007. 978-0340926529.4. Campbell N., Reece J., Taylor M., Simon. E. Biology Concepts and Connections. San Fransisco : Pearson Benjamin Cummings, 2006. 0-8053-7160-5.5. Taylor, Stephen. Science Video Resources. [Online] Wordpress, 2010. http://sciencevideos.wordpress.com.6. Burrell, John. Click4Biology. [Online] 2010. http://click4biology.info/.7. IBO. Biology Subject Guide. [Online] 2007. http://xmltwo.ibo.org/publications/migrated/production-app2.ibo.org/publication/7/part/2/chapter/1.html.<br />Self Assessment:<br />Essential BiologyAssessmentCriterionComplete (2)Partially complete (1)SelfMrTPresentation & OrganisationNAComplete and neat. All command terms highlighted, tables and diagrams well presented. Academic HonestyNASources cited using the CSE (ISO 690 numerical) method, with Works Cited section complete and correct. Objective 1 understandingAll answers for the following command terms correct:Most answers for the following command terms correct:Define Draw Label List Measure StateObjective 2 understandingAll answers for the following command terms correct:Most answers for the following command terms correct:Annotate Apply Calculate Describe Distinguish Estimate Identify OutlineObjective3understandingAll answers for the following command terms correct:Most answers for the following command terms correct:Analyse Comment Compare Construct Deduce Derive Design Determine DiscussEvaluate Explain Predict Show Solve Sketch SuggestLogic, notation, mathematical workingNAAnswers are presented in a logical and concise manner. SI units used most times, with correct unit symbols and definitions of terms. All mathematical working shown.Further researchNAEvidence is apparent of research and reading beyond the textbook and presentations to find correct answers to challenging questions. If any questions are unanswered, this criterion scores zero. Total (max 10):<br />