17. What is Sepsis? Multi-Organ Failure How does sepsis effect the various organs of the body?
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45. Proposed Algorithm for the Management of Hyperdynamic Shock Hypotension/Hypoperfusion Cardiac Index Cardiac Index (CI<4.5 l/min/m ) (CI>4.5 L/min/m ) 2 2 Preload (EDV) Preload Preload Preload (PAOP<15 mmHg) (PAOP>15) (PAOP<15) (PAOP>15) Volume Inotrope Volume Inotrope Vasopressor
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69. Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock Dellinger, et al Crit Care Med 32:858-73, 2004. Recommendations (not based on expert opinion): Human activated protein C is recommended in patients with a high risk of death. After resolution of hypoperfusion and in the absence of CAD, acute hemorrhage or lactic acidosis, transfusion of rbc’s should only be done to maintain hemoglobin > 7 gm/dl.