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…Improving Health Through Technology




          Credit Suisse Healthcare
                 Conference
                 November 14, 2012
Safe Harbor Statement
“Safe Harbor” Statement under the Private Securities Litigation Reform Act of 1995:

To the extent any statements made in this presentation contain information that is not historical, these statements are
forward-looking in nature and express the beliefs and expectations of management. Such statements are based on current
expectations and involve a number of known and unknown risks and uncertainties that could cause the Company’s future
results, performance or achievements to differ significantly from the results, performance or achievements expressed or
implied by such forward-looking statements. Such risks and uncertainties include, but are not limited to, the effect of current
economic conditions on the Company’s industry, business, financial position and results of operations, fluctuations in the
Company’s revenues and operating income, the Company’s ability to successfully develop and commercialize pharmaceutical
products, reductions or loss of business with any significant customer, the impact of consolidation of the Company’s customer
base, the impact of competition, the Company’s ability to sustain profitability and positive cash flows, any delays or
unanticipated expenses in connection with the operation of the Company’s Taiwan facility, the effect of foreign economic,
political, legal and other risks on the Company’s operations abroad, the uncertainty of patent litigation, increased government
scrutiny on the Company’s agreements with brand pharmaceutical companies, consumer acceptance and demand for new
pharmaceutical products, the difficulty of predicting Food and Drug Administration filings and approvals, the Company’s
inexperience in conducting clinical trials and submitting new drug applications, the Company’s ability to successfully conduct
clinical trials, the Company’s reliance on third parties to conduct clinical trials and testing, the availability of raw materials and
impact of interruptions in the Company’s supply chain, the use of controlled substances in the Company’s products,
disruptions or failures in the Company’s information technology systems and network infrastructure, the Company’s reliance
on alliance and collaboration agreements, the Company’s dependence on certain employees, the Company’s ability to comply
with legal and regulatory requirements governing the healthcare industry, the regulatory environment, the Company’s ability to
protect the Company’s intellectual property, exposure to product liability claims, changes in tax regulations, the Company’s
ability to manage the Company’s growth, including through potential acquisitions, the restrictions imposed by the Company’s
credit facility, uncertainties involved in the preparation of the Company’s financial statements, the Company’s ability to
maintain an effective system of internal control over financial reporting, any manufacturing difficulties or delays, the effect of
terrorist attacks on the Company’s business, the location of the Company’s manufacturing and research and development
facilities near earthquake fault lines and other risks described in the Company’s periodic reports filed with the Securities and
Exchange Commission. Forward-looking statements speak only as to the date on which they are made, and Impax
undertakes no obligation to update publicly or revise any forward-looking statement, regardless of whether new information
becomes available, future developments occur or otherwise.

Note: All product sales data included herein are derived from data published by Wolters Kluwer Health for the 12 months
ended September 2012.
Trademarks referenced herein are the property of their respective owners.
©2012 Impax Laboratories, Inc. All Rights Reserved.
2
Impax’s Dual Strategic Focus




     Unique targeted ANDAs                Create valued CNS products
     First-to-File, First-to-Market       Develop strong IP positions
     Sustainability through               IPX066 (RYTARYTM) NDA
     technically challenging,             filed 4Q11 as 505(b)(2) filing
     difficult to formulate products
     Partnership for in-licensing         IPX159 in Phase IIb as
     or co-development of                 505(b)(1) filing
     alternative dosage forms
                                          Licensed exclusive U.S.
     45 apps pending at FDA               commercialization rights to
     24 under development                 Zomig®


3     Note: Data as of November 1, 2012
Healthy Balance Sheet Supports Ongoing M&A
    Significant cash and no debt for investments in growth initiatives




                                       Strategically
                         Financially      Right
                         Attractive


                                 Manageable
                                  Execution
                                    Risk




              Generic & Brand M&A Candidates
4
Dr. Carole Ben-Maimon
President, Global Pharmaceuticals




   …A Leader in Generic Medicines
Generic Growth Initiatives




6
69 Products Pending or Under Development

                                                         Future Targeted Opportunities
                                                      $25 Billion Current U.S. Brand/Generic Sales


                       Present
                                                                                          45
                                                                                    Pending at FDA
                         48                                                             ($20 Billion)

                     Currently
                     Marketed
                      ANDAs                                                               24
                                                                               Under Development
                                                                                        ($5 Billion)

      Note: All product sales data included herein are derived from data published by
7     Wolters Kluwer Health for the 12 months ended September 2012.
Alternative Dosage Form Partnership Portfolio

                          Currently ADF portfolio of 24 products:
    – 9 approved
                                                          Brand and Generic sales >$2.7B…a number
    – 6 pending at the FDA                                of them still First-to-File or First-to-Market
    – 9 under development                                 opportunities

                                    • 9 approved products (expected launch throughout Oct/Nov 2012)
                                    • 2 topical products pending at FDA
                                    • 7 topical and other ADF products under development


                                    • 2 softgel capsule products pending at FDA


                                    • 2 nasal spray products pending at FDA


                                    • 2 topical products under development

       Note: All product sales data included herein are derived from data published by
8
       Wolters Kluwer Health for the 12 months ended September 2012.
A Snapshot of Generic Launch Opportunities

                •   Original Opana ER® (FTF – 6 months exclusivity expected)
                •   Doryx®
                •   Concerta®
2013            •   Numerous undisclosed pending ANDA opportunities


                • Trilipix®
                • Renvela® tablets (FTF - 6 months exclusivity expected)
2014            • Numerous undisclosed pending ANDA opportunities



                • Welchol® tablets (3 months exclusivity expected)
                • Numerous undisclosed pending ANDA opportunities
2015

     Note: Original Opana ER® ANDA currently approved. Commercialization of pending ANDAs
9    will depend on FDA approval and market dynamics at time of approval.
Michael Nestor
President, Impax Pharmaceuticals




     …Advancing CNS Treatment
Brand Growth Initiatives




                           Internal R&D
                             Programs



                        Approval and launch
                         of RytaryTM in U.S.
                             Market
                          Zomig® in U.S.




11
RYTARY™ (IPX066): ER Carbidopa and Levodopa

     • Extended release capsule formulation of CD-LD intended to
       maintain consistent plasma concentration of levodopa for a longer
       duration verses competitive levodopa products

     • Indicated for the symptomatic treatment of adult patients with
       idiopathic Parkinson’s disease

     • Three phase III studies completed in naive and advanced patients,
       with primary endpoint measuring reduction of “off time”




12
RYTARYTM (IPX066): Next Steps in 2012/1Q13

      Formulation Patent                  Dec.            Feb.            Jan. 21,
                                                                                          Throughout 2012/1Q13
         Information                      2011            2012             2013(a)
                                                                                         Pre-launch
                   Development Milestones
                                                                                         preparation and
                                                                                         launch planning
 1st patent granted
      Aug. 2006                                 FDA                                         Building
      Expires May 2022                   NDA acceptance PDUFA                                marketing and
                                          filed of NDA    Date                                sales team
 2nd patent submission                           Filing                                      Conducting
      Dec. 2008                                                                              commercial pre-
      Expires Dec. 2028                                                                      launch activities
                                                                                             Prepare for
                                                                                              launch in 1Q13




      (a) The Company announced on Oct. 12, 2012 that the FDA extended the PDUFA date three
13    months to review additional requested information. The initial PDUFA date was Oct. 21, 2012.
Clinical Stage Pipeline - IPX159
                                        IPX159 – Restless Legs Syndrome (RLS)
      Product                     •    Ex-US compound (for a different indication), NCE US
      Overview                    •    Inhibits uptake of neurotransmitters



       IPX159                  Phase IIb study underway
     Development
      Overview                 US registration path 505(b)(1) – 5 year regulatory exclusivity


                                                         Significant Commercial Opportunity
     RLS Market                                                                  25 million in          ~$800 million
     Opportunity                   Large                  Improve                   U.S.
                                                                                                            total          Good
                                opportunity in           Treatment               experience
                                                                                                         prescription   commercial fit
                                  the U.S.               Opportunity                RLS
                                                                                  symptoms               market size



       Note: Patient information derived from Datamonitor. All product sales data included herein are derived
       from data published by Wolters Kluwer Health and IMS NDTI June 2010.
       “Data on file, Impax Laboratories”
14
IPX159: Development Status

 Preclinical & POC   Phase I Phase IIa            Phase IIb – Initiated December 2011


                                              • Primary endpoint: International Restless
        Completed

                      Completed
                                  Completed
                                                Legs Syndrome Study Group (IRLSSG)
                                                Rating Scale
                                              • Safety and efficacy study
                                              • North America, randomized, double-
                                                blind, placebo-controlled trial
                                              • Approximately 120 subjects
                                              • 11 week trial
                                              • Results expected first quarter 2013




15
Taiwan Manufacturing Expansion

     • July 2012 FDA preapproval inspection for RYTARYTM and
       undisclosed generic drug with no Form 483 observations

     • Primary manufacturing site for RYTARYTM

     • Two year expansion project to be completed mid 2013

     • Expanded footprint provides space for installation of additional
       equipment as needed

        – Capable of supporting annual production of 2B doses




16
Strong Platform for Long Term Growth



                  Generic                       Brand
              Unique Targeted             Offering Long-Term
             High Value ANDAs               Growth Drivers




                                Drug Delivery
                                  Expertise




                            Core Competency
                           Product         Formulation
                         Development       Technology

17

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Healthcare Through Technology

  • 1. …Improving Health Through Technology Credit Suisse Healthcare Conference November 14, 2012
  • 2. Safe Harbor Statement “Safe Harbor” Statement under the Private Securities Litigation Reform Act of 1995: To the extent any statements made in this presentation contain information that is not historical, these statements are forward-looking in nature and express the beliefs and expectations of management. Such statements are based on current expectations and involve a number of known and unknown risks and uncertainties that could cause the Company’s future results, performance or achievements to differ significantly from the results, performance or achievements expressed or implied by such forward-looking statements. Such risks and uncertainties include, but are not limited to, the effect of current economic conditions on the Company’s industry, business, financial position and results of operations, fluctuations in the Company’s revenues and operating income, the Company’s ability to successfully develop and commercialize pharmaceutical products, reductions or loss of business with any significant customer, the impact of consolidation of the Company’s customer base, the impact of competition, the Company’s ability to sustain profitability and positive cash flows, any delays or unanticipated expenses in connection with the operation of the Company’s Taiwan facility, the effect of foreign economic, political, legal and other risks on the Company’s operations abroad, the uncertainty of patent litigation, increased government scrutiny on the Company’s agreements with brand pharmaceutical companies, consumer acceptance and demand for new pharmaceutical products, the difficulty of predicting Food and Drug Administration filings and approvals, the Company’s inexperience in conducting clinical trials and submitting new drug applications, the Company’s ability to successfully conduct clinical trials, the Company’s reliance on third parties to conduct clinical trials and testing, the availability of raw materials and impact of interruptions in the Company’s supply chain, the use of controlled substances in the Company’s products, disruptions or failures in the Company’s information technology systems and network infrastructure, the Company’s reliance on alliance and collaboration agreements, the Company’s dependence on certain employees, the Company’s ability to comply with legal and regulatory requirements governing the healthcare industry, the regulatory environment, the Company’s ability to protect the Company’s intellectual property, exposure to product liability claims, changes in tax regulations, the Company’s ability to manage the Company’s growth, including through potential acquisitions, the restrictions imposed by the Company’s credit facility, uncertainties involved in the preparation of the Company’s financial statements, the Company’s ability to maintain an effective system of internal control over financial reporting, any manufacturing difficulties or delays, the effect of terrorist attacks on the Company’s business, the location of the Company’s manufacturing and research and development facilities near earthquake fault lines and other risks described in the Company’s periodic reports filed with the Securities and Exchange Commission. Forward-looking statements speak only as to the date on which they are made, and Impax undertakes no obligation to update publicly or revise any forward-looking statement, regardless of whether new information becomes available, future developments occur or otherwise. Note: All product sales data included herein are derived from data published by Wolters Kluwer Health for the 12 months ended September 2012. Trademarks referenced herein are the property of their respective owners. ©2012 Impax Laboratories, Inc. All Rights Reserved. 2
  • 3. Impax’s Dual Strategic Focus Unique targeted ANDAs Create valued CNS products First-to-File, First-to-Market Develop strong IP positions Sustainability through IPX066 (RYTARYTM) NDA technically challenging, filed 4Q11 as 505(b)(2) filing difficult to formulate products Partnership for in-licensing IPX159 in Phase IIb as or co-development of 505(b)(1) filing alternative dosage forms Licensed exclusive U.S. 45 apps pending at FDA commercialization rights to 24 under development Zomig® 3 Note: Data as of November 1, 2012
  • 4. Healthy Balance Sheet Supports Ongoing M&A Significant cash and no debt for investments in growth initiatives Strategically Financially Right Attractive Manageable Execution Risk Generic & Brand M&A Candidates 4
  • 5. Dr. Carole Ben-Maimon President, Global Pharmaceuticals …A Leader in Generic Medicines
  • 7. 69 Products Pending or Under Development Future Targeted Opportunities $25 Billion Current U.S. Brand/Generic Sales Present 45 Pending at FDA 48 ($20 Billion) Currently Marketed ANDAs 24 Under Development ($5 Billion) Note: All product sales data included herein are derived from data published by 7 Wolters Kluwer Health for the 12 months ended September 2012.
  • 8. Alternative Dosage Form Partnership Portfolio Currently ADF portfolio of 24 products: – 9 approved Brand and Generic sales >$2.7B…a number – 6 pending at the FDA of them still First-to-File or First-to-Market – 9 under development opportunities • 9 approved products (expected launch throughout Oct/Nov 2012) • 2 topical products pending at FDA • 7 topical and other ADF products under development • 2 softgel capsule products pending at FDA • 2 nasal spray products pending at FDA • 2 topical products under development Note: All product sales data included herein are derived from data published by 8 Wolters Kluwer Health for the 12 months ended September 2012.
  • 9. A Snapshot of Generic Launch Opportunities • Original Opana ER® (FTF – 6 months exclusivity expected) • Doryx® • Concerta® 2013 • Numerous undisclosed pending ANDA opportunities • Trilipix® • Renvela® tablets (FTF - 6 months exclusivity expected) 2014 • Numerous undisclosed pending ANDA opportunities • Welchol® tablets (3 months exclusivity expected) • Numerous undisclosed pending ANDA opportunities 2015 Note: Original Opana ER® ANDA currently approved. Commercialization of pending ANDAs 9 will depend on FDA approval and market dynamics at time of approval.
  • 10. Michael Nestor President, Impax Pharmaceuticals …Advancing CNS Treatment
  • 11. Brand Growth Initiatives Internal R&D Programs Approval and launch of RytaryTM in U.S. Market Zomig® in U.S. 11
  • 12. RYTARY™ (IPX066): ER Carbidopa and Levodopa • Extended release capsule formulation of CD-LD intended to maintain consistent plasma concentration of levodopa for a longer duration verses competitive levodopa products • Indicated for the symptomatic treatment of adult patients with idiopathic Parkinson’s disease • Three phase III studies completed in naive and advanced patients, with primary endpoint measuring reduction of “off time” 12
  • 13. RYTARYTM (IPX066): Next Steps in 2012/1Q13 Formulation Patent Dec. Feb. Jan. 21, Throughout 2012/1Q13 Information 2011 2012 2013(a) Pre-launch Development Milestones preparation and launch planning 1st patent granted  Aug. 2006 FDA  Building  Expires May 2022 NDA acceptance PDUFA marketing and filed of NDA Date sales team 2nd patent submission Filing  Conducting  Dec. 2008 commercial pre-  Expires Dec. 2028 launch activities  Prepare for launch in 1Q13 (a) The Company announced on Oct. 12, 2012 that the FDA extended the PDUFA date three 13 months to review additional requested information. The initial PDUFA date was Oct. 21, 2012.
  • 14. Clinical Stage Pipeline - IPX159 IPX159 – Restless Legs Syndrome (RLS) Product • Ex-US compound (for a different indication), NCE US Overview • Inhibits uptake of neurotransmitters IPX159 Phase IIb study underway Development Overview US registration path 505(b)(1) – 5 year regulatory exclusivity Significant Commercial Opportunity RLS Market 25 million in ~$800 million Opportunity Large Improve U.S. total Good opportunity in Treatment experience prescription commercial fit the U.S. Opportunity RLS symptoms market size Note: Patient information derived from Datamonitor. All product sales data included herein are derived from data published by Wolters Kluwer Health and IMS NDTI June 2010. “Data on file, Impax Laboratories” 14
  • 15. IPX159: Development Status Preclinical & POC Phase I Phase IIa Phase IIb – Initiated December 2011 • Primary endpoint: International Restless Completed Completed Completed Legs Syndrome Study Group (IRLSSG) Rating Scale • Safety and efficacy study • North America, randomized, double- blind, placebo-controlled trial • Approximately 120 subjects • 11 week trial • Results expected first quarter 2013 15
  • 16. Taiwan Manufacturing Expansion • July 2012 FDA preapproval inspection for RYTARYTM and undisclosed generic drug with no Form 483 observations • Primary manufacturing site for RYTARYTM • Two year expansion project to be completed mid 2013 • Expanded footprint provides space for installation of additional equipment as needed – Capable of supporting annual production of 2B doses 16
  • 17. Strong Platform for Long Term Growth Generic Brand Unique Targeted Offering Long-Term High Value ANDAs Growth Drivers Drug Delivery Expertise Core Competency Product Formulation Development Technology 17