1. By: Khuram aziz Cell signaling: Communication Between Cells and Their Environment Study hard and stay focused on your educational goals. But always have a backup plan! Remember: while chance favors the prepared mind, you can’t always be where the lighting strikes. Overview of intracellular signaling: Initiation and responses
22. Take home message #2 Hydrolysis is the turn-off signal that induces heterotrimeric G protein subunits (G ) to disengage their effectors. Note change in structure of GTP versus GDP bound G protein
25. Do you remember everything from yesterday’s lecture? If you say yes, you get a donut! If not, then you need to pay attention to the CREB story. Fact: CREB: cAMP response element binding protein. Binds to DNA at the CRE (cAMP Response Element) and activates transcription.
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28. cAMP is generated from ATP by an enzyme: adenylyl cyclase. AC is regulated by G proteins