The final exam for the Chemical Information Retrieval course CHEM367/767 in 2009 by Jean-Claude Bradley at Drexel University. http://getcheminfo.wikispaces.com/

1. Chemical Information Retrieval Final Exam
2009
Drexel University - Instructor: Jean-Claude Bradley
1. Give 5 examples of primary sources (5 points)
2. Give 5 examples of secondary or tertiary sources (5 points)
3. Give 5 examples of sections in a typical journal article (5 points)
4. Give 5 examples of article-level metrics (5 points)
5. Give 3 examples of Creative Commons licenses (3 points)
6. List 2 of the 4 criteria used to determine if the use of a copyrighted work is considered
fair (2 points)
7. List 5 free chemistry databases (5 points)
8. List 3 commercial chemistry databases that Drexel provides (3 points)

2. All Questions below 1 point each
9. What does DOI stand for?
10. The Beilstein Journal of Organic Chemistry charges this much for publication
a. nothing
b. $400
c. $800
d. $1700
e. 23 to 38 Euros per page
f. $95 per page
11. The printing press was invented in:
a. 1236
b. 1336
c. 1436
d. 1536
e. 1636
12. In a double-blind review:
a. the editor and reviewers don't know who the author is
b. the editor and author don't know who the reviewers are
c. the editor knows who the author and reviewers are
d. the author knows who the editor and reviewers are
e. the reviewers don't know who the editor and author are
13. In an open review system
a. the author may recommend reviewers
b. the author may not recommend reviewers
c. the author must recommend reviewers
d. the reviewer may not know who the author is
e. the editor must use one of the author's recommended reviewers
14. The 2005 Thomson Impact Factor is calculated by
a. dividing the number of citations in 2005 by the number of citable articles in 2005
b. dividing the number of citations in 2005 by the number of citable articles in 2004
c. dividing the number of citations in 2005 and 2004 by the number of citable articles in
2004 and 2005
d. dividing the number of citations in 2004 and 2003 by the number of citable articles in
2004 and 2003
e. dividing the number of citations in 2005, 2004 and 2003 by the number of citable articles
in 2005, 2004 and 2003
15. How many ILL requests may Drexel undergraduates make in a term?
a. 0
b. 5
c. 10
d. 20
e. 100
f. unlimited

3. 16. The American Chemical Society
a. does not permit self-archiving under any conditions
b. does permit self-archiving under any conditions
c. permits self-archiving for papers resulting from work funded by the National Science
Foundation
d. allows authors to pay to make their articles Open Access
e. pays authors to self-archive their papers
17. Drexel's repository is an example of
a. Green Access
b. Gold Access
c. Green and Gold Access
d. neither Green or Gold
e. Drexel does not have a repository
18. Which of the following takes into account the importance of incoming citations?
a. Thomson Impact Factor
b. Eigenfactor
c. Web of Science
d. Citation Summary Factor
e. none of the above
19. During peer review:
a. reviewers must repeat at least one experiment in the submitted paper
b. reviewers are expected to redo every calculation in the submitted paper
c. reviewers are paid at least minimum wage for their effort
d. reviewers ensure that nonsense cannot be included in the peer-reviewed literature
e. none of the above
20. What percentage of Open Access chemistry journals charge a publication fee?
a. 0%
b. 42%
c. 49%
d. 9%
e. 100%
21. Harold Varmus founded:
a. PubChem
b. Public Library of Science
c. arXiv
d. PNAS
e. Thomson Impact Factor
22. Many identifiers can be associated with a chemical structure. Which of these is MOST
appropriate to enable structure based searching across the internet via Google?
a. Molfile
b. InChI String
c. InChIKey
d. ChemSpider ID

4. 23. Which of the following identifiers can be used to resolve to a scientific article on the
web.
a. CAS Number
b. Digital Object Identifier
c. InChI Key
d. Publication ID
24. Which of the following structure databases offers the ability for crowdsourced curation of
the data?
a. PubChem
b. ChemSpider
c. Sigma Aldrich website
d. NIST Webbook
25. If two molecules are identical what is their Tanimoto similarity?
a. 0.5
b. 0.0
c. 1.0
d. 1.5
26. Suppose we define a fingerprint of 4 bits: Bit 1 (from the left) corresponds to the
presence of aromaticity, bit 2 corresponds to the presence of carboxyl groups, bit 3
corresponds to the presence of amide bonds and bit 4 corresponds to the presence of an
allylic group. With this definition what is the fingerprint for benzoic acid?
a. 1100
b. 0000
c.1111
d 1011
27. If you do not have the 3D structure of a protein target, which virtual screening method
can you *not* use
a. QSAR
b. Substructure searching
c. Docking
d. Similarity searching