Jean-Claude Bradley presents at the OpenSciNY conference on May 14, 2010 on Open Notebooks Science and Scientific Scholarship.

1. Open Notebook Science Jean-Claude Bradley May 14, 2010 OpenSciNY Associate Professor of Chemistry Drexel University

2. What is a Scientific Precedent? What is a Scientific Publication? What is Peer Review? What is Scholarship?

3. Asked to Review an Article…

12. “ I would never consider a claim made in a patent as blocking an author's claim of novelty.” Langmuir Editor What is a Scientific Precedent in Academia? What is a Scientific Precedent in Patent Law?

13. Chemistry Preprint Archive (Elsevier)

14. What is Scholarship?

15. What is Peer Review?

16. The Scandal of Bell’s Lab Notebook

17. How bad is our current system? Try to find the solubility EGCG?

18. =2.3 g/L WTF?!

19. The End of the Chain of Provenance

20. The NaH oxidation controversy

21. Information spreads quickly through the blogosphere

22. 15% NMR yield

24. Khalid Mirza and Marshall Moritz

26. Top results on a Google search

27. Motivation: Faster Science, Better Science

28. Open Notebook Science Logos (Andy Lang, Shirley Wu) Sharing: how much and when

29. There are NO FACTS, only measurements embedded within assumptions Open Notebook Science maintains the integrity of data provenance by making assumptions explicit

30. TRUST PROOF

31. The solubility of 4-chlorobenzaldehyde

32. The Log makes Assumptions Explicit

33. The Rationale of Findings Explicit

34. Raw Data Made Public Splatter? Some liquid

35. YouTube for demonstrating experimental set-up

36. Calculations Made Public on Google Spreadsheets

37. Revision History on Google Spreadsheets

38. Wiki Page History

39. Comparing Wiki Page Versions

40. Proof of Purity with interactive NMR spectrum using JSpecView and JCAMP-DX

41. Linking to Molecules in Chemistry Databases

42. Experimental Spectra and User-Deposited Data on ChemSpider

43. (Andy Lang, Tony Williams) Open Data JCAMP spectra for education (Andy Lang, Tony Williams, Robert Lancashire)

44. Database Curation via Game Playing

45. Over 100,000 spectrum views so far - worldwide

46. Link Spectral Game to Open Educational Content

47. The Ugi reaction: can we predict precipitation? Can we predict solubility in organic solvents?

48. Crowdsourcing Solubility Data

49. ONS Submeta Award Winners

50. ONS Challenge Judges

51. Teaching Lab: Brent Friesen (Dominican University)

52. Solubility Experiment List

53. Solubilities collected in a Google Spreadsheet

54. Rajarshi Guha’s Live Web Query using Google Viz API

55. WE ARE HERE How can the scientific process become more automated?

56. Semi-Automated Measurement of solubility via web service analysis of JCAMP-DX files (Andy Lang)

58. Understanding in addition to empirical modeling Missed in a prior publication on solubility for this compound

59. Data provenance: From Wikipedia to…

60. … the lab notebook and raw data

61. Including links to the literature

63. Paper written on Wiki

64. References to papers, blog posts, lab notebook pages, raw data

65. Paper on Journal of Visualized Experiments (JoVE)

66. Pre-print on Nature Precedings

67. ChemSpider Automated Mark-up of Chemical Names

68. BUT… Open Access: the Choice that Keeps Giving.. and Giving…

69. Beware of your addiction to metrics: redundancy will reduce them

70. Cameron Neylon’s Notebooks Other Open Notebooks

71. Anthony Salvagno’s Notebook (Steve Koch group)

73. Librarians and Science 2.0 "The Internet Archive is a 501(c)(3) non-profit that was founded to build an Internet library, with the purpose of offering permanent access for researchers, historians, and scholars to historical collections that exist in digital format." The internet Archive is not practical for practitioners of Open Notebook Science or Science 2.0

74. Good concept but.....

75. Most pages look like this....

76. Where We Began: The ONS backup spreadsheet and ONSPreserver

77. Publishing Google Spreadsheets as XLS

78. ONSArchive: Semi-Automated Snapshot of the Entire Scientific Record

79. Snapshot is Self-Contained and Live on the Internet

80. Lulu.com Data Disks

81. DSpace – Handle (hdl)

82. Bradley, Jean-Claude; Lang Andrew. Solubilities Summary Sheet. Open Notebook Science Challenge. 2009-12-11. URL:http://spreadsheets.google.com/pub?key=plwwufp30hfq0udnEmRD1aQ&output=xls. Accessed: 2009-12-11. (Archived by WebCite® at http://www.webcitation.org/5lx5ry3BV )

83. Lulu.com - ISBN Google Spreadsheets Google Documents Web Services ChemSpider & Indiana Real Time Linear Regression, Unit Conversions, Style Sheet, etc Data Book

86. Solubility Prediction (Andy Lang uses Abraham Model)

87. Reaction Attempts Book

88. Reaction Attempts Book: Reactants listed Alphabetically

89. For all Formats of ONS Projects