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Mitchell Wong, MD PhD
Director, KL2 Program
UCLA CTSI KL2
Translational Science Award
Award Overview
• Career development support for junior faculty
within the UCLA CTSI Consortium
• Interdisciplinary, translational science (basic,
clinical and HSR)
• Similar in structure to K08/K23 award
Support
• Annual award, renewable for up to 3-years
• Support
– $75k salary plus benefits
– $25k research support
– $4k for tuition or coursework
– $2k for travel
– $1500 for statistical support in addition to in-kind
support from DOM Stats
Eligibility
• Doctoral level research degree or professional degree
(with advanced research training)
• Faculty level title as of July 1, 2014 at a UCLA CTSI
Institution
• Commit 75% of effort to translational research and aims
of the KL2 (50% minimum for some specialties like
surgery)
• U.S. Citizen or non-citizen national, permanent U.S.
resident
Eligibility (Prior/Pending Grant)
• May have had a small grant (R03, R21)
• May have had prior K12 funding (total K funding cannot
exceed 5 years)
• Cannot have:
– Prior or current PI of a NIH R01 or equivalent non-PHS
reviewed research grant (direct costs>$100k per year)
– Prior or current PI of a K08/K23 award
– Prior or current PI of a VA Career Development or R01
Equivalent grant
– PI of a pending K award application, pending R award in similar
area
– Current co-investigator funding on an R01/Project grant
Future Funding for KL2
• KL2 Awardees may apply for K08/K23 or VA CDAs
– Must relinquish KL2 if awardee receives NIH/VA CDA
– Total CDA funding (KL2 + individual CDA) cannot exceed 5
years.
• KL2 Awardees may apply for R01, Program grants
– Must maintain 75% effort on KL2 in year 1
– May decrease to 50% effort in last 2 years of K support
Selection Criteria
1. Proposed research-
Quality, innovation, significance, feasibility, promise for
future funding, relevance to
interdisciplinary, translational research
2. Candidate- Training, productivity, promise
3. Mentor- Track record in mentorship and
research, commitment to candidate
4. Educational Plan- Well described and planned, fit with
research plan, provides candidate with new skill set
5. (Environment)- Commitment from
institution, department/division, availability of support
and resources to conduct research and educational
Application Components
• Letter of intent- Name, mentor, title, biosketch, specific aims (to help
KL2 selection committee identify appropriate reviewers)
• Application (6 pages)- Research, Education and Career Plan
• Mentor’s Letter (2 pages)
• Institutional Letter (2 pages) from department chair or division chief
• Letters of support (2 max)
• Candidate’s CV and other support page
• Mentor’s Biosketch
• Budget and budget justification
• References
• Data and Safety Monitoring Plan (when applicable)
• Appendices allowable (e.g. letter of support for use of equipment or
data)
Timeline
• Letter of intent deadline early February 2014
• Application deadline late February 2014
• Awardees will be notified in late April 2014
• Grant start date July 1, 2014
• Research funds will not be released until IRB
approval received
Common Pitfalls
• Inadequate education plan that does not tie in to
research plan
• Lack of clear commitment from
division/department
• Not in a faculty position by 7/1/2014
Common Questions
• Is start date flexible? No
• Can postdoctoral fellows apply? Yes, if they have a faculty appointment
no later than 7/1/2014
• Does the mentor need to be at a UCLA CTSI Institution? No, but
distance mentoring is difficult so if the primary mentor is not local, that
may raise concern.
• Does the project have to involve direct patient contact? No.
• Ok to have a VA CDA? No.
• Can an applicant have a J1 Visa? No.
• I don’t have my junior faculty appointment yet? Need an appointment
by 7/1/2014. If in process, have the chief or chair indicate in their letter
the commitment to your faculty appointment by 7/1/2014.

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UCLA CTSI KL2 Award (July 25, 2013)

  • 1. Mitchell Wong, MD PhD Director, KL2 Program UCLA CTSI KL2 Translational Science Award
  • 2. Award Overview • Career development support for junior faculty within the UCLA CTSI Consortium • Interdisciplinary, translational science (basic, clinical and HSR) • Similar in structure to K08/K23 award
  • 3. Support • Annual award, renewable for up to 3-years • Support – $75k salary plus benefits – $25k research support – $4k for tuition or coursework – $2k for travel – $1500 for statistical support in addition to in-kind support from DOM Stats
  • 4. Eligibility • Doctoral level research degree or professional degree (with advanced research training) • Faculty level title as of July 1, 2014 at a UCLA CTSI Institution • Commit 75% of effort to translational research and aims of the KL2 (50% minimum for some specialties like surgery) • U.S. Citizen or non-citizen national, permanent U.S. resident
  • 5. Eligibility (Prior/Pending Grant) • May have had a small grant (R03, R21) • May have had prior K12 funding (total K funding cannot exceed 5 years) • Cannot have: – Prior or current PI of a NIH R01 or equivalent non-PHS reviewed research grant (direct costs>$100k per year) – Prior or current PI of a K08/K23 award – Prior or current PI of a VA Career Development or R01 Equivalent grant – PI of a pending K award application, pending R award in similar area – Current co-investigator funding on an R01/Project grant
  • 6. Future Funding for KL2 • KL2 Awardees may apply for K08/K23 or VA CDAs – Must relinquish KL2 if awardee receives NIH/VA CDA – Total CDA funding (KL2 + individual CDA) cannot exceed 5 years. • KL2 Awardees may apply for R01, Program grants – Must maintain 75% effort on KL2 in year 1 – May decrease to 50% effort in last 2 years of K support
  • 7. Selection Criteria 1. Proposed research- Quality, innovation, significance, feasibility, promise for future funding, relevance to interdisciplinary, translational research 2. Candidate- Training, productivity, promise 3. Mentor- Track record in mentorship and research, commitment to candidate 4. Educational Plan- Well described and planned, fit with research plan, provides candidate with new skill set 5. (Environment)- Commitment from institution, department/division, availability of support and resources to conduct research and educational
  • 8. Application Components • Letter of intent- Name, mentor, title, biosketch, specific aims (to help KL2 selection committee identify appropriate reviewers) • Application (6 pages)- Research, Education and Career Plan • Mentor’s Letter (2 pages) • Institutional Letter (2 pages) from department chair or division chief • Letters of support (2 max) • Candidate’s CV and other support page • Mentor’s Biosketch • Budget and budget justification • References • Data and Safety Monitoring Plan (when applicable) • Appendices allowable (e.g. letter of support for use of equipment or data)
  • 9. Timeline • Letter of intent deadline early February 2014 • Application deadline late February 2014 • Awardees will be notified in late April 2014 • Grant start date July 1, 2014 • Research funds will not be released until IRB approval received
  • 10. Common Pitfalls • Inadequate education plan that does not tie in to research plan • Lack of clear commitment from division/department • Not in a faculty position by 7/1/2014
  • 11. Common Questions • Is start date flexible? No • Can postdoctoral fellows apply? Yes, if they have a faculty appointment no later than 7/1/2014 • Does the mentor need to be at a UCLA CTSI Institution? No, but distance mentoring is difficult so if the primary mentor is not local, that may raise concern. • Does the project have to involve direct patient contact? No. • Ok to have a VA CDA? No. • Can an applicant have a J1 Visa? No. • I don’t have my junior faculty appointment yet? Need an appointment by 7/1/2014. If in process, have the chief or chair indicate in their letter the commitment to your faculty appointment by 7/1/2014.