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CHRONIC	OTITIS	AND	
CHOLESTEATOMA	
F.	Benoudiba,	Jl	Sarrazin	
Service	de	Neuroradiologie	
CHU	Kremlin	Bicêtre	
JFIM	BARCELONA	nov	2014
Cholesteatoma	
Chronic	otitis	
Cholesteatoma	
No	cholesteatoma	
Retraction	pocket	
pre	cholesteatoma	
state	
Acquired	Cholesteatoma
Retraction	pocket	
§  Mesotympanic pocket
retraction uncontrollable
and no self cleaning
§  (accumulation of epidermal
scales
Precholesteatoma state
Acquired	cholesteatoma	
u Aetiology
Pocket retraction or
marginal perforation
with malpighian
epithelium migration
coming from the
external cavity
u 80% of cholesteatoma
From	a	pocket	retraction…	to	
cholesteatoma
Imaging	
§  CHOLESTEATOMA IS A CLINICAL DIAGNOSIS
§  Modern imaging plays a key role in management of
cholesteatoma:
§  In pre operative
§  In post operative : minimally invasive supervision
(avoid surgical 2nd look)
§  Technical imaging:
ú  CT scan (+++)
ú  MRI : growing up
   Essentially in post operative
   Before surgery when complications
Imaging
	
§  Which imaging technique:
ú  CT scan without enhancement: first choice
modality
   To assess the diagnosis when otoscopy is
inclonclusive (closed tympanic membran)
   To screen for complications
   For the staging
   Anatomical assessment of the tympanomastoid cavity
   Surgical approach Choice
Imaging	semiology	
§  Nodular tisssular mass
ú  Convex, rounded,
polycyclic
ú  location : Prussak’s
space (External attical
wall)
ú  Attical extension
§  Mass effect on
ossicular chain
Imaging	semiology	
§  Bone erosion
ú  Erosion of the external
epitympanic wall
(scutum): early sign
ú  Ossicular erosion: 70%
ú  Not specific
   Long process of incus
   Incus body
   Head of malleus
Imaging	semiology	
§  Mastoid antrum extension
§  Enlargement of additus
§  Disappearance	of	mastoid		
cell	trabeculation
Imaging	semiology	
§  Exceptionally, the
tissular mass may be
absent
§  It has been removed
by the ENT physician
just before the CT
scan
§  Empty pocket
Congenital	cholesteatoma	
§  Unusual
§  Pathogenetic explanation:
persistence of residual
squamous cells usually
existing in embryo between
the 10th and the 30th week
of gestation (Mickaels’
theory).
Congénital	Cholesteatoma	
§  Petrous apex
§  EAC
§  Hypotympanum
§  Petrous pyramid
Complications	
§  Erosion of the
LSCC
(rarely the posterior)
§  Tegmen destruction
§  Carotid canal
erosion
Erosion of the facial canal
Complications	
§  Intralabyrinthine
Extension (MRI+++)
§  Intra cranial
extension
§  Cerebral infection
Surgical	approach	
§  Canal	wall	up	with		tympanoplasty
CAUTION	
§  Prolapsed	and	superficial	
sigmoid	sinus	
§  Jugular	vein	
§  Emissary	vein	
§  Intrapetrous	carotid
CAUTION	
§  Prolapsed	Tegmen	
§  Temporal	meningocele
Surgical	approach	
§  Canal	wall	down	mastoidectomy
Hearing	rehabilitation	
Kurz	TTP	Vario	(Collin)	
Universal	prosthesis	titane	
(Xomed-Medtronic)	
Spiggle&Theis	
Titanium	middle	ear	
partial-total	implant	
(Pouret	Médical)
Ossicular	prosthesis	
II	
III
Prosthesis	
PORP	 TORP
Rehabilation	prosthesis	
TORP	
PORP	
Double	tray	tympanoplasty	
Incus	transposition
Cholesteatoma:	post	
operative	following	
§  Imaging of post operative cholesteatoma
ú  To assess a residual cholesteatoma
ú  Staging (extension/complications) if residual or
recurrent cholesteatoma.
ú  Post operative hearing loss without explanation
ú  Best choice of imaging: depends on the situation
MRI:	
u Technical MRI
T2 HR
T1 SE
Diffusion non EPI or SE
+/- T1 with contrast
enhancement
MRI:	results	
T1	 T2	
b1000	 ADC	 T1	Gado	
Cholesteatoma	
Fibrosis	
granuloma	
abcess	
Thiriat S Am J Neuroradiol 2009
MRI	diffusion:	False	positive	
§  Cerumen	
§  Sebaceous	cyst	
§  Cholesterol	
Granuloma
How	to	avoid	the	false	
positive	
§  Well	located	the	lesion	
ú  Correlate	different	sequences	and	the	CT	scan	
	
§  Correlate	non	Epi	and	ADC	
§  Cholesteatoma:		decrease	ADC	
§  	T1	WI	without	contrast:	
ú  hyperintense:	It’s	not	a	cholesteatoma
Residual	cholesteatoma
Residual	cholesteatoma
Image	fusion:	anatomical	
location
Children	
§  Avoid iterative CT scan (radiation)
§  Prefer MRI diffusion
§  1 month after surgery
§  No injection
§  Binary response: chole + or chole –
ú  Chole + : surgery (+/- CT)
ú  Chole – : MRI (1 month later)
Adult	
§  Good audition , no otorrhea: 1 question
ú  Residual Cholesteatoma?
§  Conductive hearing loss or mixed: 2 questions
ú  Residual Cholesteatoma?
ú  Functional evaluation
Clinical
No opacity
Audition OK Hearing loss
CT
Partial
opacity
Total opacity
Post	operative	monitoring	
Dubuous
image
No doubt Residual No
residual
Audition
OK Hearing loss
surgery Surgery
Ossicular
rehabilita
tion
CT
Ossicular
rehabilitation
CT CT or MRI
MRI	
12 months
12,24 months 12 ,24months 12 ,24months
Post	operative	hearing	loss	
§  Failure : persistence or recurrence of
conductive hearing loss
§  Complication : occured of a sensorineural
hearing loss
Failure	of	rehabilitation	
Incus	transposition	
displacement	
	PORP	dislocation
Asensorineural hearing loss 	
Labyrinthitis	ossificant
Conclusion	
§  Major role of imaging for the diagnosisof pre
operative cholesteatoma
§  Systematic in pre operative: the first modality
imaging is CT scan without contrast
§  CT may be supplemented by MRI if
complications (labyrinthine fistula or extension,
tegmen erosion, intra cranial extension,
meningocele)

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