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AMG	
  
Adjusted	
  Morbidity	
  Groups	
  
调整后的发病族群	
  
A	
  new	
  mul5-­‐morbidity	
  grouper	
  
新的多种疾病族群	
  
Barcelona	
  
巴塞罗那	
  
	
  
Emili	
  
Vela	
  
Montse	
  
Clèries	
  
David	
  Monterde	
  
Foreword	
  and	
  mo5va5on:	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  前言和动机:	
  
The	
  relevance	
  of	
  mul5-­‐morbidity	
   	
  多种疾病的相关性
Mul7-­‐morbidity	
  is	
  the	
  norm	
  rather	
  than	
  the	
  excep5on	
  
多种疾病是经常发生的状况而非例外
Pa7ents	
  with	
  mul7-­‐morbidity	
  show	
  lower	
  quality	
  life	
  scores,	
  and	
  demand	
  higher	
  health	
  care	
  resources	
  
患有多种疾病的患者显示较低的生活质量积分,而且需要较多保健资源
Low	
  effec7veness	
  of	
  disease-­‐oriented	
  treatment	
  in	
  mul7-­‐morbidity	
  pa7ents	
  
多种疾病患者疾病导向治疗效益低落
A	
  tool	
  to	
  measure	
  mul7-­‐morbidity	
  is	
  required	
  
需要能够测量多种疾病的工具
Mul7-­‐morbidity	
  benchmarking	
  goes	
  beyond	
  of	
  just	
  lis5ng	
  of	
  (chronic)	
  diagnoses	
  involved	
  
多种疾病标竿分析不仅只是列出相关的(慢性)诊断
Other	
  factors	
  such	
  as	
  “total	
  mul7-­‐morbidity	
  load”	
  must	
  also	
  be	
  take	
  into	
  considera7on	
  
其他像是“多种疾病总体负荷”也必须列入考虑
The	
  Lancet,	
  BMJ,	
  J	
  Clinical	
  Epidemiology,	
  JAMA,	
  Ann	
  Fam	
  Pract	
  
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
CRG
AMG	
  
Mul5-­‐morbidity	
  aggregator	
  elements	
  	
  多种疾病族群组成因素	
  
MORBIDITY-­‐BASED	
  
以发病为基础
POPULATION	
  
	
  
人口
AGGREGATOR	
  
MODEL	
  
群集模式
CLUSTERING	
  
	
  
群集
STRATIFICATION	
  
	
  
分层
IDENTIFICATION	
  
	
  
识别
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
Health	
  care	
  quality	
  医疗质量	
  
	
  
Efficiency	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  效率	
  
	
  
Benchmarking	
  	
  	
  	
  	
  	
  	
  	
  	
  标竿分析	
  
	
  
Evalua7on	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  评估	
  
	
  
Decision	
  criteria	
  	
  	
  	
  	
  	
  决策标准	
  
	
  
Mul5-­‐morbidity	
  aggregator	
  benefits	
  多种疾病族群的益处	
  
•  Health	
  care	
  prac5ce	
  医疗工作
•  Informa7on	
  for	
  professionals	
  	
  提供专业人员信息
•  Pa7ent	
  iden7fica7on	
  患者识别
•  Chronic	
  pa7ent	
  follow-­‐up	
  慢性患者追踪
•  Preven7ve	
  ac7ons	
  on	
  high	
  risk	
  pa7ents	
  
高危险患者的预防措施
•  Indicators	
  management	
  指标管理
•  Predic7ve	
  model	
  design	
  预测模型设计
•  Benchmarking	
  标竿分析
•  Con7nued	
  improvement	
  持续改善
•  Resource	
  management	
  资源管理
•  Human	
  resources	
  management	
  人力资源管理
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
Mul5-­‐morbidity	
  aggregator	
  benefits	
  	
  	
  多种疾病族群的益处
DECISION	
  SUPPORT	
  
决策支持	
  
KNOWLEDGE	
  
知识	
  
INFORMATION	
  
信息	
  
GMA	
   UTILITIES
效⽤用	
  
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
Clinical	
  data	
  sources:	
  Big	
  Data	
  临床数据资源:	
  大数据	
  
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
*	
  Available	
  informa5on	
  belonging	
  to	
  the	
  7.5	
  milion	
  inhabitants	
  	
  
(during	
  the	
  analysis	
  period	
  and	
  previous	
  years)	
  
	
  
*	
  获得 750 万居民的信息	
  
(在分析期间与过去几年)	
  
Yearly	
  data	
  of	
  7.5	
  million	
  ci3zens:	
  	
  	
  	
  	
   	
  750	
  万公民年度数据:	
  
	
  
v 	
  700.000	
  hospitaliza7ons	
   	
   	
  70 万住院人次	
  
v 	
  45	
  millions	
  of	
  primary	
  care	
  visits	
   	
  4 千 5	
  百万一级保健人
次	
  
v 	
  4	
  millions	
  emergency	
  room	
  visits	
   	
  4	
  百万急诊室人次	
  
v 	
  1	
  million	
  visits	
  to	
  Mental	
  Health	
  centers	
   	
  1	
  百万心理卫生中心人次	
  
v 	
  100.000	
  visits	
  to	
  socio-­‐sanitary	
  centers	
   	
  10 万社康中心人次	
  
v 	
  150	
  millions	
  of	
  drug	
  prescrip7ons	
   	
  1 亿 5 千万药物处方	
  
v 	
  	
  62	
  millions	
  of	
  diagnoses	
  records	
   	
  6 千 2	
  百万诊断记录	
  
7.5	
  million	
  ci5zens	
  	
  
750	
  万公民	
  
	
  
267	
  million	
  diagnoses	
  *	
  
2 亿 6 千 7	
  百万项诊断	
  *	
  	
  
255	
  million	
  visits	
  *	
  
2 亿 5 千 5	
  百万人次	
  *	
  	
  
360	
  million	
  prescrip5ons	
  *	
  
3 亿 6 千万件处方	
  *	
  
AMG	
  Basic	
  Architecture	
  	
  	
  基本结构	
  
Disease	
  profile	
  疾病档案	
  
Acute,	
  chronic	
  or	
  ac7ve	
  cancer	
  
急性、慢性或目前患有癌症	
  
	
  
Mul5-­‐morbidity	
  多种疾病	
  
On	
  pa7ents	
  with	
  chronic	
  disease	
  
慢性疾病的患者	
  
	
  
Complexity	
  复杂性	
  
Based	
  on	
  morbidity	
  burden	
  
依据发病负荷	
  
ACTIVE CANCER	
  	
  
目前患有癌症	
  
CHRONIC DISEASE (4+ SYSTEMS)	
  
慢性疾病 (4 个以上系统)	
  
CHRONIC DISEASE (2-3 SYSTEMS)	
  
慢性疾病 (2-3 个系统)	
  
CHORNIC DISEASE (1 SYSTEM)	
  
慢性疾病 (1 个系统)	
  
ACUTE PATHOLOGY	
  	
  
急性病理	
  
PREGNANCY AND DELIVERTY	
  	
  
怀孕与分娩	
  
HEALTHY POPULATION	
  	
  
健康人口	
  
1	
   2	
   3	
   4	
   5	
  
1	
   2	
   3	
   4	
   5	
  
1	
   2	
   3	
   4	
   5	
  
1	
   2	
   3	
   4	
   5	
  
1	
   2	
   3	
   4	
   5	
  
1	
   2	
   3	
   4	
   5	
  
1	
  
MAJOR MORBIDITY GROUP	
  	
  
重要疾病族群	
  
COMPLEXITY LEVEL	
  
复杂等级
MULTI-MORBIDITY
多种疾病
COMPLEXITY

复杂性
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
Pa5ent	
  level	
  informa5on	
  患者等级信息	
  
AMG	
  
	
  
	
  
Health	
  profile
健康档案	
  
	
  
	
  
Complexity	
  
复杂性	
  
DIABETIS	
  	
  
糖尿病	
  
COPD	
  
慢性阻塞性肺病	
  
HBP	
  	
  
高血压	
  
ARTHROSIS	
  
关节炎	
  
MIGRAINE	
  
偏头痛	
  
BACK	
  PAIN	
  	
  
背痛	
  
1	
   2	
   3	
   4	
   5	
  
1	
   2	
   3	
   4	
   5	
  
1	
   2	
   3	
   4	
   5	
  
1	
   2	
   3	
   4	
   5	
  
1	
   2	
   3	
   4	
   5	
  
1	
   2	
   3	
   4	
   5	
  
1	
  
COPD+	
  DIABETIS	
  +	
  HBP	
  +	
  ARTHOSIS	
  	
  
慢性阻塞性肺病 +	
  糖尿病	
  +	
  高血压	
  +	
  关节炎 	
  
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
Adjusted	
  Morbidity	
  Groups:	
   	
  调整后的发病族群:	
  
A	
  new	
  mul5-­‐morbidity	
  grouper	
  新的多种疾病族群	
  
AMGs	
  classify	
  pa5ents	
  into	
  unique	
  groups	
  
AMG	
  将患者分为单独的组别	
  
Each	
  pa7ent	
  belongs	
  to	
  a	
  unique	
  group	
  
每位患者都有各自的族群	
  
	
  
AMGs	
  take	
  into	
  account	
  the	
  health	
  profile	
  
AMG	
  将健康档案列入考虑	
  
It	
  specifically	
  dis7nguish	
  between	
  acute,	
  chronic	
  and	
  ac7ve	
  cancer	
  at	
  a	
  
certain	
  period	
  
特别区分急性、慢性以及各时期的癌症	
  
	
  
AMGs	
  provide	
  specific	
  informa5on	
  on	
  each	
  pa5ent	
  
AMG	
  提供每位患者的特定信息	
  
Each	
  pa7ent	
  has	
  its	
  own	
  health	
  profile	
  (morbidity	
  summary)	
  and	
  his	
  complexity	
  level	
  
(according	
  to	
  the	
  care	
  demand	
  level	
  associated	
  to	
  his	
  morbidity	
  profile)	
  
每位患者皆有自己的健康档案 (疾病摘要)	
  与复杂等级 (依据与患者疾病
档案相关的护理需求等级)	
  
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
Evalua5on	
  of	
  AMGs	
  explanatory	
  strength	
  	
  评估 AMG	
  的判断能力	
  
	
  
	
  
0	
  
5	
  
10	
  
15	
  
20	
  
25	
  
30	
  
35	
  
40	
  
Edad	
  +	
  Sexo	
   Edad	
  +	
  Sexo	
  +	
  
Charlson	
  
Edad	
  +	
  Sexo	
  +	
  
ACG	
  
PRIMARY	
  CARE	
  VISITS	
  
一级护理人次	
  
%	
  OF	
  VARIABILITY	
  	
  EXPLAINED	
  
%	
  判断变异性	
  
“Comparing	
  measures	
  of	
  
mul5-­‐morbidity	
  to	
  
predict	
  outcomes	
  in	
  
primary	
  care:	
  	
  a	
  cross	
  
sec5onal	
  study”	
  
“多种疾病比较方式	
  
预测一级护理结果:	
  
一项跨领域研究”	
  
	
  
	
  
Brilleman,	
  Samuel	
  L	
  and	
  Salisbury,	
  
Chris	
  2013.	
  Family	
  Prac+ce	
  
	
  
AGE	
  +	
  
GENDER	
  
	
  
年龄	
  +	
  
性别	
  
AGE	
  +	
  
GENDER	
  +	
  
CHARLSON	
  
年龄	
  +	
  
性别	
  +	
  
CHARLSON	
  
AGE	
  	
  +	
  
GENDER	
  +	
  
ACG	
  
年龄	
  +	
  
性别	
  +	
  	
  
ACG	
  
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
0	
  
10	
  
20	
  
30	
  
40	
  
50	
  
60	
  
Edad	
  +	
  Sexo	
   Edad	
  +	
  Sexo	
  +	
  
n	
  Crónicas	
  
Edad	
  +	
  Sexo	
  +	
  
GMA	
  
PRIMARY	
  CARE	
  VISIT	
  
一级护理人次	
  
%	
  OF	
  VARIABILITY	
  	
  EXPLAINED	
  
%	
  判断变异性	
  
0	
  
10	
  
20	
  
30	
  
40	
  
50	
  
60	
  
Edad	
  +	
  Sexo	
   Edad	
  +	
  Sexo	
  +	
  
n	
  Crónicas	
  
Edad	
  +	
  Sexo	
  +	
  
GMA	
  
PHARMACY	
  SHOP	
  VISIT	
  
药局选购	
  
%	
  OF	
  VARIABILITY	
  	
  EXPLAINED	
  
%判断变异性	
  
0.60	
  
0.65	
  
0.70	
  
0.75	
  
0.80	
  
0.85	
  
Edad	
  +	
  Sexo	
   Edad	
  +	
  Sexo	
  
+	
  n	
  Crónicas	
  
Edad	
  +	
  Sexo	
  
+	
  GMA	
  
HOSPITAL	
  ADMISSION	
  RISK	
  
住院风险	
  
AUC	
  (ROC)	
  
Evalua5on	
  of	
  AMGs	
  explanatory	
  power	
  	
  	
  	
  	
  	
  评估 AMG	
  的判斷优势	
  
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
AGE	
  +	
  	
  
GENDER	
  +	
  	
  
AMG	
  
年龄	
  +	
  	
  
性别	
  +	
  
	
  AMG	
  
AGE	
  +	
  	
  
GENDER	
  +	
  	
  
CRG	
  
年龄	
  +	
  	
  
性别	
  +	
  	
  
CRG	
  
AGE	
  +	
  	
  
GENDER	
  +	
  	
  
N	
  CHRONIC	
  
年龄	
  +	
  	
  
性别	
  +	
  	
  
N	
  CHRONIC	
  
AGE	
  +	
  	
  
GENDER	
  
	
  
年龄	
  +	
  	
  
性别	
  
AGE	
  +	
  	
  
GENDER	
  +	
  
CHARLSON	
  
年龄	
  +	
  	
  
性别	
  +	
  
CHARLSON	
  
AGE	
  +	
  	
  
GENDER	
  +	
  	
  
AMG	
  
年龄	
  +	
  	
  
性别	
  +	
  
	
  AMG	
  
AGE	
  +	
  	
  
GENDER	
  +	
  	
  
CRG	
  
年龄	
  +	
  	
  
性别	
  +	
  	
  
CRG	
  
AGE	
  +	
  	
  
GENDER	
  +	
  	
  
N	
  CHRONIC	
  
年龄	
  +	
  	
  
性别	
  +	
  	
  
N	
  CHRONIC	
  
AGE	
  +	
  	
  
GENDER	
  
	
  
年龄	
  +	
  	
  
性别	
  
AGE	
  +	
  	
  
GENDER	
  +	
  
CHARLSON	
  
年龄	
  +	
  	
  
性别	
  +	
  
CHARLSON	
  
AGE	
  +	
  	
  
GENDER	
  +	
  	
  
AMG	
  
年龄	
  +	
  	
  
性别	
  +	
  
	
  AMG	
  
AGE	
  +	
  	
  
GENDER	
  +	
  	
  
CRG	
  
年龄	
  +	
  	
  
性别	
  +	
  	
  
CRG	
  
AGE	
  +	
  	
  
GENDER	
  +	
  	
  
N	
  CHRONIC	
  
年龄	
  +	
  	
  
性别	
  +	
  	
  
N	
  CHRONIC	
  
AGE	
  +	
  	
  
GENDER	
  
	
  
年龄	
  +	
  	
  
性别	
  
AGE	
  +	
  	
  
GENDER	
  +	
  
CHARLSON	
  
年龄	
  +	
  	
  
性别	
  +	
  
CHARLSON	
  
0	
  
5	
  
10	
  
15	
  
20	
  
25	
  
30	
  
Edad	
  +	
  Sexo	
   Edad	
  +	
  Sexo	
  +	
  
CRG	
  
Edad	
  +	
  Sexo	
  +	
  
GMA	
  
RISK	
  OF	
  URGENCY	
  ROOM	
  ADMISSION	
  
急诊室住院风险	
  
SENSIBILITY	
  (VP+)	
  
敏感度(VP+)	
  
Evalua5on	
  of	
  AMGs	
  predic5ve	
  power	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  评估 AMG	
  的预测优势	
  
AGE	
  +	
  GENDER	
  +	
  AMG	
  
年龄	
  +	
  	
  
性别	
  +	
  	
  
AMG	
  
AGE	
  +	
  GENDER	
  +	
  CRG	
  
年龄	
  +	
  	
  
性别	
  +	
  	
  
CRG	
  
AGE	
  +	
  GENDER	
  
年龄	
  +	
  
性别	
  
The	
  predic7ve	
  power	
  of	
  AMGs	
  is	
  
under	
  evalua7on	
  
AMG	
  的预测能力受到低估	
  
	
  
	
  
The	
  threshold	
  used	
  is	
  the	
  meaningful	
  
epidemiologic	
  value,	
  rather	
  than	
  the	
  
op7mum	
  predictor	
  value	
  
使用的阈值是有效流行病学数值,
而非最佳预测值	
  
	
  
	
  
	
  
	
  
	
  
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
Popula5on	
  stra5fica5on	
  using	
  AMG	
  使用 AMG	
  将人口分层 	
  
	
  MORTALITY	
  	
  	
  ADMISSIONS	
  	
  	
  	
  EXPENSE	
  	
  	
  	
  	
  	
  	
  TOTAL	
  
死亡率 住院率 花费 总百分比	
  
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
MORTALITY: deaths per 1000 inhabitants
死亡率:每 1000 位居民死亡数
ADMISSIONS: admissions per 100 inhabitants
住院率:每 100 位居民住院数
EXPENSE: annual cost per patient
花费: 每位患者年度花费
TOTAL: % compared to the total
总百分比:相较总数之百分比
CHRONIC	
  DISEASE	
  IN	
  4+	
  SYSTEMS	
  	
  	
  
四个以上的系统患有慢性疾病	
  
COPD	
  +	
  T2D+	
  HBP	
  +	
  ARTHROSIS	
  +	
  PANCREATITIS	
  
慢性阻塞性肺病 +	
  第二型糖尿病 +	
  高血压	
  +	
  关节炎	
  +	
  胰脏炎	
  
	
  
	
   	
   	
  RISK	
  OF	
  DEATH:	
  	
  死亡风险:	
  
	
   	
   	
  RISK	
  OF	
  ADMISSION:	
  住院风险:	
  
Integra5ng	
  of	
  AMG	
  into	
  case	
  management	
  将 AMG	
  用于病例管理	
  
PATIENT:	
   	
  John	
  Smith	
  
患者: 	
  王大年	
  
AGE: 	
  67	
  
年龄: 	
  67	
  岁	
  
GENDER: 	
  MALE	
  
性别: 	
  男性	
  
AMG	
  +	
  HEALTH	
  PROFILE	
  
AMG	
  +	
  健康档案	
  
COMPLEXITY	
  LEVEL	
  
复杂等级	
  
INDICATORS	
  &	
  AUTOMATED	
  
RISK-­‐BASED	
  ALERTS	
  	
  
指标与自动风险基准警示	
  
FOLLOW	
  UP	
  REQUIRED	
  
需要追踪	
  
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
Summary	
  总结	
  
High	
  explanatory	
  strength	
   	
  高判断能力	
  
Explanatory	
  strength	
  has	
  been	
  validates	
  and	
  benchmarked	
  against	
  alterna7ve	
  measurement	
  
methodologies	
  
判断能力与替代测量方案比较评估证实	
  
	
  
High	
  predic5ve	
  strength	
  	
   	
  高预测能力	
  
Predic7ve	
  strength	
  has	
  been	
  validates	
  and	
  benchmarked	
  against	
  alterna7ve	
  measurement	
  
methodologies	
  
预测能力与替代测量方案比较评估证实	
  
	
  
Clinically	
  tested	
   	
   	
  经过临床检测	
  
Predic7ve	
  strength	
  has	
  been	
  validates	
  and	
  benchmarked	
  against	
  alterna7ve	
  measurement	
  
methodologies	
  
AMG	
  经过临床管理与复杂性测量证实	
  
	
  
Flexible	
  and	
  adaptable	
   	
   	
  灵活性与适应性	
  
As	
  AMGs	
  are	
  generated	
  by	
  a	
  quan7ta7ve,	
  empirical	
  complexity	
  model,	
  it	
  can	
  be	
  re-­‐calculated	
  
using	
  current	
  health	
  care	
  informa7on	
  system	
  data	
  (popula7on)	
  
AMG 以定量、实证的复杂性模型制作,可使用目前保健信息系统数据 (人口) 重新计算	
  
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  
Emili	
  
Vela	
  
Montse	
  
Clèries	
  
David	
  
Monterde	
  
Thank	
  you	
  for	
  your	
  aden5on	
  感谢您的关注	
  
Adjusted	
  morbidity	
  groups	
  调整后的发病族群	
  

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Adjusted Morbidity Groups (AMG) 调整后的发病族群

  • 1. AMG   Adjusted  Morbidity  Groups   调整后的发病族群   A  new  mul5-­‐morbidity  grouper   新的多种疾病族群   Barcelona   巴塞罗那     Emili   Vela   Montse   Clèries   David  Monterde  
  • 2. Foreword  and  mo5va5on:                              前言和动机:   The  relevance  of  mul5-­‐morbidity    多种疾病的相关性 Mul7-­‐morbidity  is  the  norm  rather  than  the  excep5on   多种疾病是经常发生的状况而非例外 Pa7ents  with  mul7-­‐morbidity  show  lower  quality  life  scores,  and  demand  higher  health  care  resources   患有多种疾病的患者显示较低的生活质量积分,而且需要较多保健资源 Low  effec7veness  of  disease-­‐oriented  treatment  in  mul7-­‐morbidity  pa7ents   多种疾病患者疾病导向治疗效益低落 A  tool  to  measure  mul7-­‐morbidity  is  required   需要能够测量多种疾病的工具 Mul7-­‐morbidity  benchmarking  goes  beyond  of  just  lis5ng  of  (chronic)  diagnoses  involved   多种疾病标竿分析不仅只是列出相关的(慢性)诊断 Other  factors  such  as  “total  mul7-­‐morbidity  load”  must  also  be  take  into  considera7on   其他像是“多种疾病总体负荷”也必须列入考虑 The  Lancet,  BMJ,  J  Clinical  Epidemiology,  JAMA,  Ann  Fam  Pract   Adjusted  morbidity  groups  调整后的发病族群  
  • 3. CRG AMG   Mul5-­‐morbidity  aggregator  elements    多种疾病族群组成因素   MORBIDITY-­‐BASED   以发病为基础 POPULATION     人口 AGGREGATOR   MODEL   群集模式 CLUSTERING     群集 STRATIFICATION     分层 IDENTIFICATION     识别 Adjusted  morbidity  groups  调整后的发病族群  
  • 4. Health  care  quality  医疗质量     Efficiency                                    效率     Benchmarking                  标竿分析     Evalua7on                                评估     Decision  criteria            决策标准     Mul5-­‐morbidity  aggregator  benefits  多种疾病族群的益处   •  Health  care  prac5ce  医疗工作 •  Informa7on  for  professionals    提供专业人员信息 •  Pa7ent  iden7fica7on  患者识别 •  Chronic  pa7ent  follow-­‐up  慢性患者追踪 •  Preven7ve  ac7ons  on  high  risk  pa7ents   高危险患者的预防措施 •  Indicators  management  指标管理 •  Predic7ve  model  design  预测模型设计 •  Benchmarking  标竿分析 •  Con7nued  improvement  持续改善 •  Resource  management  资源管理 •  Human  resources  management  人力资源管理 Adjusted  morbidity  groups  调整后的发病族群  
  • 5. Mul5-­‐morbidity  aggregator  benefits      多种疾病族群的益处 DECISION  SUPPORT   决策支持   KNOWLEDGE   知识   INFORMATION   信息   GMA   UTILITIES 效⽤用   Adjusted  morbidity  groups  调整后的发病族群  
  • 6. Clinical  data  sources:  Big  Data  临床数据资源:  大数据   Adjusted  morbidity  groups  调整后的发病族群   *  Available  informa5on  belonging  to  the  7.5  milion  inhabitants     (during  the  analysis  period  and  previous  years)     *  获得 750 万居民的信息   (在分析期间与过去几年)   Yearly  data  of  7.5  million  ci3zens:            750  万公民年度数据:     v   700.000  hospitaliza7ons      70 万住院人次   v   45  millions  of  primary  care  visits    4 千 5  百万一级保健人 次   v   4  millions  emergency  room  visits    4  百万急诊室人次   v   1  million  visits  to  Mental  Health  centers    1  百万心理卫生中心人次   v   100.000  visits  to  socio-­‐sanitary  centers    10 万社康中心人次   v   150  millions  of  drug  prescrip7ons    1 亿 5 千万药物处方   v     62  millions  of  diagnoses  records    6 千 2  百万诊断记录   7.5  million  ci5zens     750  万公民     267  million  diagnoses  *   2 亿 6 千 7  百万项诊断  *     255  million  visits  *   2 亿 5 千 5  百万人次  *     360  million  prescrip5ons  *   3 亿 6 千万件处方  *  
  • 7. AMG  Basic  Architecture      基本结构   Disease  profile  疾病档案   Acute,  chronic  or  ac7ve  cancer   急性、慢性或目前患有癌症     Mul5-­‐morbidity  多种疾病   On  pa7ents  with  chronic  disease   慢性疾病的患者     Complexity  复杂性   Based  on  morbidity  burden   依据发病负荷   ACTIVE CANCER     目前患有癌症   CHRONIC DISEASE (4+ SYSTEMS)   慢性疾病 (4 个以上系统)   CHRONIC DISEASE (2-3 SYSTEMS)   慢性疾病 (2-3 个系统)   CHORNIC DISEASE (1 SYSTEM)   慢性疾病 (1 个系统)   ACUTE PATHOLOGY     急性病理   PREGNANCY AND DELIVERTY     怀孕与分娩   HEALTHY POPULATION     健康人口   1   2   3   4   5   1   2   3   4   5   1   2   3   4   5   1   2   3   4   5   1   2   3   4   5   1   2   3   4   5   1   MAJOR MORBIDITY GROUP     重要疾病族群   COMPLEXITY LEVEL   复杂等级 MULTI-MORBIDITY 多种疾病 COMPLEXITY
 复杂性 Adjusted  morbidity  groups  调整后的发病族群  
  • 8. Pa5ent  level  informa5on  患者等级信息   AMG       Health  profile 健康档案       Complexity   复杂性   DIABETIS     糖尿病   COPD   慢性阻塞性肺病   HBP     高血压   ARTHROSIS   关节炎   MIGRAINE   偏头痛   BACK  PAIN     背痛   1   2   3   4   5   1   2   3   4   5   1   2   3   4   5   1   2   3   4   5   1   2   3   4   5   1   2   3   4   5   1   COPD+  DIABETIS  +  HBP  +  ARTHOSIS     慢性阻塞性肺病 +  糖尿病  +  高血压  +  关节炎   Adjusted  morbidity  groups  调整后的发病族群  
  • 9. Adjusted  Morbidity  Groups:    调整后的发病族群:   A  new  mul5-­‐morbidity  grouper  新的多种疾病族群   AMGs  classify  pa5ents  into  unique  groups   AMG  将患者分为单独的组别   Each  pa7ent  belongs  to  a  unique  group   每位患者都有各自的族群     AMGs  take  into  account  the  health  profile   AMG  将健康档案列入考虑   It  specifically  dis7nguish  between  acute,  chronic  and  ac7ve  cancer  at  a   certain  period   特别区分急性、慢性以及各时期的癌症     AMGs  provide  specific  informa5on  on  each  pa5ent   AMG  提供每位患者的特定信息   Each  pa7ent  has  its  own  health  profile  (morbidity  summary)  and  his  complexity  level   (according  to  the  care  demand  level  associated  to  his  morbidity  profile)   每位患者皆有自己的健康档案 (疾病摘要)  与复杂等级 (依据与患者疾病 档案相关的护理需求等级)   Adjusted  morbidity  groups  调整后的发病族群  
  • 10. Evalua5on  of  AMGs  explanatory  strength    评估 AMG  的判断能力       0   5   10   15   20   25   30   35   40   Edad  +  Sexo   Edad  +  Sexo  +   Charlson   Edad  +  Sexo  +   ACG   PRIMARY  CARE  VISITS   一级护理人次   %  OF  VARIABILITY    EXPLAINED   %  判断变异性   “Comparing  measures  of   mul5-­‐morbidity  to   predict  outcomes  in   primary  care:    a  cross   sec5onal  study”   “多种疾病比较方式   预测一级护理结果:   一项跨领域研究”       Brilleman,  Samuel  L  and  Salisbury,   Chris  2013.  Family  Prac+ce     AGE  +   GENDER     年龄  +   性别   AGE  +   GENDER  +   CHARLSON   年龄  +   性别  +   CHARLSON   AGE    +   GENDER  +   ACG   年龄  +   性别  +     ACG   Adjusted  morbidity  groups  调整后的发病族群  
  • 11. 0   10   20   30   40   50   60   Edad  +  Sexo   Edad  +  Sexo  +   n  Crónicas   Edad  +  Sexo  +   GMA   PRIMARY  CARE  VISIT   一级护理人次   %  OF  VARIABILITY    EXPLAINED   %  判断变异性   0   10   20   30   40   50   60   Edad  +  Sexo   Edad  +  Sexo  +   n  Crónicas   Edad  +  Sexo  +   GMA   PHARMACY  SHOP  VISIT   药局选购   %  OF  VARIABILITY    EXPLAINED   %判断变异性   0.60   0.65   0.70   0.75   0.80   0.85   Edad  +  Sexo   Edad  +  Sexo   +  n  Crónicas   Edad  +  Sexo   +  GMA   HOSPITAL  ADMISSION  RISK   住院风险   AUC  (ROC)   Evalua5on  of  AMGs  explanatory  power            评估 AMG  的判斷优势   Adjusted  morbidity  groups  调整后的发病族群   AGE  +     GENDER  +     AMG   年龄  +     性别  +    AMG   AGE  +     GENDER  +     CRG   年龄  +     性别  +     CRG   AGE  +     GENDER  +     N  CHRONIC   年龄  +     性别  +     N  CHRONIC   AGE  +     GENDER     年龄  +     性别   AGE  +     GENDER  +   CHARLSON   年龄  +     性别  +   CHARLSON   AGE  +     GENDER  +     AMG   年龄  +     性别  +    AMG   AGE  +     GENDER  +     CRG   年龄  +     性别  +     CRG   AGE  +     GENDER  +     N  CHRONIC   年龄  +     性别  +     N  CHRONIC   AGE  +     GENDER     年龄  +     性别   AGE  +     GENDER  +   CHARLSON   年龄  +     性别  +   CHARLSON   AGE  +     GENDER  +     AMG   年龄  +     性别  +    AMG   AGE  +     GENDER  +     CRG   年龄  +     性别  +     CRG   AGE  +     GENDER  +     N  CHRONIC   年龄  +     性别  +     N  CHRONIC   AGE  +     GENDER     年龄  +     性别   AGE  +     GENDER  +   CHARLSON   年龄  +     性别  +   CHARLSON  
  • 12. 0   5   10   15   20   25   30   Edad  +  Sexo   Edad  +  Sexo  +   CRG   Edad  +  Sexo  +   GMA   RISK  OF  URGENCY  ROOM  ADMISSION   急诊室住院风险   SENSIBILITY  (VP+)   敏感度(VP+)   Evalua5on  of  AMGs  predic5ve  power                    评估 AMG  的预测优势   AGE  +  GENDER  +  AMG   年龄  +     性别  +     AMG   AGE  +  GENDER  +  CRG   年龄  +     性别  +     CRG   AGE  +  GENDER   年龄  +   性别   The  predic7ve  power  of  AMGs  is   under  evalua7on   AMG  的预测能力受到低估       The  threshold  used  is  the  meaningful   epidemiologic  value,  rather  than  the   op7mum  predictor  value   使用的阈值是有效流行病学数值, 而非最佳预测值             Adjusted  morbidity  groups  调整后的发病族群  
  • 13. Popula5on  stra5fica5on  using  AMG  使用 AMG  将人口分层    MORTALITY      ADMISSIONS        EXPENSE              TOTAL   死亡率 住院率 花费 总百分比   Adjusted  morbidity  groups  调整后的发病族群   MORTALITY: deaths per 1000 inhabitants 死亡率:每 1000 位居民死亡数 ADMISSIONS: admissions per 100 inhabitants 住院率:每 100 位居民住院数 EXPENSE: annual cost per patient 花费: 每位患者年度花费 TOTAL: % compared to the total 总百分比:相较总数之百分比
  • 14. CHRONIC  DISEASE  IN  4+  SYSTEMS       四个以上的系统患有慢性疾病   COPD  +  T2D+  HBP  +  ARTHROSIS  +  PANCREATITIS   慢性阻塞性肺病 +  第二型糖尿病 +  高血压  +  关节炎  +  胰脏炎          RISK  OF  DEATH:    死亡风险:        RISK  OF  ADMISSION:  住院风险:   Integra5ng  of  AMG  into  case  management  将 AMG  用于病例管理   PATIENT:    John  Smith   患者:  王大年   AGE:  67   年龄:  67  岁   GENDER:  MALE   性别:  男性   AMG  +  HEALTH  PROFILE   AMG  +  健康档案   COMPLEXITY  LEVEL   复杂等级   INDICATORS  &  AUTOMATED   RISK-­‐BASED  ALERTS     指标与自动风险基准警示   FOLLOW  UP  REQUIRED   需要追踪   Adjusted  morbidity  groups  调整后的发病族群  
  • 15. Summary  总结   High  explanatory  strength    高判断能力   Explanatory  strength  has  been  validates  and  benchmarked  against  alterna7ve  measurement   methodologies   判断能力与替代测量方案比较评估证实     High  predic5ve  strength      高预测能力   Predic7ve  strength  has  been  validates  and  benchmarked  against  alterna7ve  measurement   methodologies   预测能力与替代测量方案比较评估证实     Clinically  tested      经过临床检测   Predic7ve  strength  has  been  validates  and  benchmarked  against  alterna7ve  measurement   methodologies   AMG  经过临床管理与复杂性测量证实     Flexible  and  adaptable      灵活性与适应性   As  AMGs  are  generated  by  a  quan7ta7ve,  empirical  complexity  model,  it  can  be  re-­‐calculated   using  current  health  care  informa7on  system  data  (popula7on)   AMG 以定量、实证的复杂性模型制作,可使用目前保健信息系统数据 (人口) 重新计算   Adjusted  morbidity  groups  调整后的发病族群  
  • 16. Emili   Vela   Montse   Clèries   David   Monterde   Thank  you  for  your  aden5on  感谢您的关注   Adjusted  morbidity  groups  调整后的发病族群