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- 1. National Science Council, Taipei, Taiwan A Fantastic Journey of Learning Innovative Medical Devices in Stanford University and Silicon Valley John Tsung-Chun Lee, M.D. Staff Physician Clinical Instructor Gastroenterology, Internal Medicine, National Taiwan University Hospital 2012/04/11 E-mail: johnlee0212@gmail.com www.linkedin.com/in/johntclee
- 2. 國科會報告 , 台北 , 台灣 一位台灣醫生走出象牙塔外之 美國史丹福大學與矽谷高階醫療器材產 業的奇幻旅程 李宗錞醫師 內科 胃腸肝膽科 消化內視鏡專科 主治醫師 教育部部定講師 台灣大學醫學院 台大醫院 2012/04/11 E-mail: johnlee0212@gmail.com www.linkedin.com/in/johntclee
- 3. Outline • One-year journey at Stanford and Silicon Valley • Biodesign Program • Ecosystem of medical device industry • What we can do in Taiwan • Alumnus’ view on STB program – Recruit, in-program, afterwards • National Architect to replicate Silicon Valley! • Ｄ isclosure 2012/04/11 copyright John Tsung-Chun Lee 3
- 4. Stanford University (established since 1891) 2012/04/11 copyright John Tsung-Chun Lee 4
- 5. Stanford-Taiwan Biomedical (STB) program • Since October 2008, 2 batches per year • A group of physicians, engineers • Duration: one-year – 2010/10/01 – 2011/09/30 • Hosted by Prof. Peter Fitzgerald – Cardiovascular Medicine, School of Medicine, Stanford – Engineer, Interventional cardiologist, Inventor, Venture Capitalist • Office at – Center for Cardiovascular Technologies (CCVT) – Stanford University Medical Center (SUMC) • Status – Visiting Scholar of Stanford University – Audit classes of interest (medical, engineering, business schools) 2012/04/11 copyright John Tsung-Chun Lee 5
- 6. Where do innovation come from? 2012/03/09 copyright John Tsung-Chun Lee 6
- 7. My journey- 3 essential credits 2012/04/11 copyright John Tsung-Chun Lee 7
- 8. 2012/03/09 copyright John Tsung-Chun Lee 8 http://www.siliconmaps.com/silicon_valley.html
- 9. The Silicon Valley Way (mindset) • Dream Big ! • Change the world ! • Dare to dream • Dare to try • Rapid prototyping • Fail fast then try another one • Rapid iteration • Lean startup • Partnership between entrepreneur and venture capitalist • “The StartUp Game” (William H Draper III) 2012/04/11 copyright John Tsung-Chun Lee 9 http://www.amazon.com
- 10. Design thinking (d.school at Stanford Univ) "Human–Centered Design" How to conduct an high-impact brainstorming: •Warming-up •Empathy: prime sub-consciousness •Focus – problem – Status quo and Specifications •Explore four quadrants for insights – X-axis: Logics & Emotion – Y-axis: Spoken & Unspoken •Creative within constraints • Time; Resources •Forget all the rules, Let’s brainstorm! •Think by prototyping; Try by prototyping 2012/04/11 copyright John Tsung-Chun Lee 10
- 11. Design thinking crash course at d.school, 2012/03/09 Stanford Univ., 2011/01/08 copyright John Tsung-Chun Lee 11
- 12. Snapshot at d.school 2012/04/11 Design thinking crash course at d.school, copyright John Tsung-Chun Lee 12 Stanford Univ., 2011/01/08
- 13. Creativity comes with child-like excitement 2012/04/11 Design thinking crash course at d.school, copyright John Tsung-Chun Lee 13 Stanford Univ., 2011/01/08
- 14. Dialogue between MD and Engineer 雞同鴨講？ 非也 , 異中求同 - 同中求創新 ! Apprenticeship; Different tracks Vall Silicon Valle CBA: Biotech, Life Science Organization in Bay Area, California - A Biotech ORGANIZATION MEMB 2012/03/09 copyright John Tsung-Chun Lee HOME AB OU T U S EVENTS NEWS MEMBERS 14 CONTACT Board Members Advisors
- 15. Biodesign thinking process -new thinking, forget about SCI ! • Identification (Disease insight) • Solid unmet clinical need • Large market potential; Back-of-envelop analysis • Innovation (Device insight) • Design thinking • Rapid iteration • Implementation (Business insight) • Three hurdles to overcome: Intellectual Property, Regulatory, Reimbursement • Clinical adoption, Sales and Marketing, Channels • Business model • Exit strategies 2012/03/09 copyright John Tsung-Chun Lee 15
- 16. P. G. Yock, T. J. Brinton, S. A. Zenios, Teaching Biomedical Technology 2012/03/09 copyright John Tsung-Chun Lee Discipline. Sci. Transl. Med. 3, 92cm18 (2011). 16 Innovation as a DOI: 10.1126/scitranslmed.3002222
- 17. Essence of Bio-design • Design: purposeful invention for the good of patients • Patient – first; Patient – centered; Patient - oriented • Disruptive innovation, not incremental improvement or cost-down approach (although affordable medicine is the trend) • Market-driven (global market, emerging market, niche market) • Reasonable anticipated return • Therapeutic device better than diagnostic • Multi-disciplinary approach/team from beginning to end • Rapid iteration • Industrial feedback (instant, timely, practical) • Business project, not scientific project for SCI academic publications 2012/03/09 copyright John Tsung-Chun Lee 17
- 18. Secrets of successful innovation for entrepreneurs • Find solid, data-proven unmet clinical need • Passion about it • Follow you heart • Dive deep, Know everything about it • Find the best professionals to form a complimentary team • Form hypothesis along the way, test and revise • Rapid iteration • Intellectual property (IP) portofolio protection as the most early and important task 2012/04/11 copyright John Tsung-Chun Lee 18
- 19. Eco-System of medical device industry • Entrepreneurial team • Venture capitalist, Angel investor • Design and prototyping companies • Pre-clinical testing companies • Attorneys (IP, Legal, Accounting, M & A, IPO) • Consultants (regulatory, manufacturing, reimbursement) • Doctors, Scientists, Hospitals • Contrast Research Organizations (CRO, trialists) • Businessmen (Salesforce, Marketing, Channels) • Experienced entrepreneurs, mentors 2012/04/11 copyright John Tsung-Chun Lee 19
- 20. Importance of networking • “Silicon Valley is built on “Merit”( 成人之美 ) (Trust) • “Merit rules out” (John Roos, CEO of WSGR) • Proximity within Silicon Valley area: work & life together • We need to – Learn from them about “Insider’s know-how” – Get involved – Tap into the US medical device value chain 2012/04/11 copyright John Tsung-Chun Lee 20
- 21. Building connections … LinkedIn, Tweeter Medical Device conferences Starbucks coffee, Peet’s coffee, … 2012/04/11 copyright John Tsung-Chun Lee 21
- 22. Cross-Pacific Strategy -- Rooted in Taiwan, Leveraging Silicon Valley 2012/04/11 copyright John Tsung-Chun Lee 22
- 23. Strategies to design and build EcoSystem of medical device industry in Taiwan • Bottom-up and Top-down approaches • What resources do we have ? • Incentives for stakeholders inside and outside Taiwan ? 2012/04/11 copyright John Tsung-Chun Lee 23
- 24. Taiwan’s advantages Precision manufacture P. G. Yock, T. J. Brinton, S. A. Zenios, Teaching Biomedical Technology 2012/03/09 copyright John Tsung-Chun Lee Discipline. Sci. Transl. Med. 3, 92cm18 (2011). 24 Innovation as a DOI: 10.1126/scitranslmed.3002222
- 25. What are missing? Entrepreneurs, Job-shifting Talents, Experienced Executives P. G. Yock, T. J. Brinton, S. A. Zenios, Teaching Biomedical Technology 2012/03/09 copyright John Tsung-Chun Lee Discipline. Sci. Transl. Med. 3, 92cm18 (2011). 25 Innovation as a DOI: 10.1126/scitranslmed.3002222
- 26. What can we do in Taiwan ? • Biodesign innovation workshops – Educate physicians, engineers, and investors • Clinical shadow observation in the hospital – Source of unmet needs and new ideas • Prototyping services for medical devices – Rapid iteration, proof-of-concept testing • Early-stage investment in medical devices – Government or Corporate seed funding • First-in-man trials in Taiwan • Close and continuous connection with Silicon Valley 2012/04/11 copyright John Tsung-Chun Lee 26
- 27. Important professionals in Silicon Valley Dr. Paul Yock Dr. Peter Dr. Jay Pasricha Mark Deem Jim Swick Fitzgerald, CV, Biodesign GI, Innovator CTO, Foundry Ex-CTO, LyChron CV, VC Dr. Yue-Teh Jang Dr. Joseph Yang Entrepreneur, VC TECO, San Francisco 2012/04/11 copyright John Tsung-Chun Lee 27
- 28. Taiwan -- innovation starts from here! Conceived in Taiwan First-Trialed in Taiwan “ 台灣發想 矽谷設計 台歐認證 行銷全球 ” 2012/04/11 copyright John Tsung-Chun Lee 28
- 29. 居廟堂之高 ，則憂其民 范仲淹 岳陽樓記 替未來的年青學子 謝謝國科會的長官們
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