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Chapter (1) Introduction to EEG
Agenda  Introduction. History. Neural Activities. Action Potentials. EEG Generation. Brain Rhythms. EEG Recording and Measurement. Conditioning the Signals. Abnormal EEG Patterns. Ageing. Mental Disorders.
Agenda  Introduction. History. Neural Activities. Action Potentials. EEG Generation. Brain Rhythms. EEG Recording and Measurement. Conditioning the Signals. Abnormal EEG Patterns. Ageing. Mental Disorders.
Introduction The human brain activity start between 4-5 months before parental development. The human brain represent the brain functional side to side the status of the whole body. EEG signals measured from the brain of a human. The medium defines the path from neurons, as so called signal sources to electro nodes which are the sensors.
             studying neural functions and neurophysicological properties of the brain together with the mechanisms underlying the generation of the signals for detection, diagnosis and treatment of brain disorders and the related diseases.  Note :-
Agenda  Introduction. History. Neural Activities. Action Potentials. EEG Generation. Brain Rhythms. EEG Recording and Measurement. Conditioning the Signals. Abnormal EEG Patterns. Ageing. Mental Disorders.
History  Carlo Matteucci (1811–1868) and Emil Du Bois-Reymond (1818–1896) were the first people to register the electrical signals emitted from muscle nerves using a galvanometer and established the concept of neurophysiology. Analysis of EEG signals started during the early days of EEG measurement. Berger assisted by Dietch (1932) applied Fourier analysis to EEG sequences.
[object Object],Nerve Cell. glia Cell.
[object Object],                                  it consists of         Axons                           Dendrites                 Cell Bodies
Nerve cell components Axons :- ,[object Object]
Transmits an electrical impulse and can be several meters long in vertebrates.
In animals can be several meters but in humans the length can be a percentage of millimeter to a meter .
An axonal transport system for delivering proteins to the ends of the cell exists and the transport system has ‘molecular motors’, which ride upon tubulin rails.,[object Object]
1 nerve cell connected 10,000 other nerve cells.,[object Object]
Agenda  Introduction. History. Neural Activities. Action Potentials. EEG Generation. Brain Rhythms. EEG Recording and Measurement. Conditioning the Signals. Abnormal EEG Patterns. Ageing. Mental Disorders.
Neural Activities A potential of 60–70 mV with negative polarity may be recorded under the membrane of the cell body. ,[object Object]
If an action potential travels along the fibre, which ends in an excitatory synapse, an excitatory postsynaptic potential (EPSP) occurs in the following neuron.
If two action potentials travel along the same fibre over a short distance, there will be a summation of EPSPs producing an action potential on the postsynaptic neuron providing a certain threshold of membrane potential is reached.,[object Object]
Note  ,[object Object],         EEG + DC potentials = Abnormalities in the           brain. ,[object Object],[object Object]
Action Potentials (AP) APs are caused by an exchange of ions across the neuron membrane and an AP is a temporary change in the membrane potential that is transmitted along the axon. The conduction velocity of action potentials lies between 1 and 100 m/s. APs are initiated by many different types of stimuli; sensory nerves respond to many types of stimuli, such as chemical, light, electricity, pressure, touch, and stretching.
Action potentials processes The action must be more than gate threshold value. Depolarization . Sodium gates close. 4.   Potassium gates open. Repolarization. Hyperpolarization.
EEG Generation ,[object Object]
Brain cells active mode (get a new action potential), the cell produced within dendrites so this current generate a magnetic field (EMG) that cover over scalp.
By the anatomical of the human head we found that it consists of three main layers.1-scalp  2-skull 3-brain ,[object Object]
When the human receive the action he could feel 1 % of the action, as it arrives to his brain and the other noise generated within scalp and skull.
Therefore, to feel action potential there must be a lot of active neurons can generate potential.
When the human born, he got a large number of neurons (10^11) nerve.,[object Object]
The amplitudes and frequencies of such signals change from one to another.
This waves from low to high (alpha , theta, beta ,delta ,gamma)
The history about found this frequencies.
Draft that show the frequencies' of this signals.(figure 1.7),[object Object]
Agenda  Introduction. History. Neural Activities. Action Potentials. EEG Generation. Brain Rhythms. EEG Recording and Measurement. Conditioning the Signals. Abnormal EEG Patterns. Ageing. Mental Disorders.
EEG Recording and Measurement                                                     Signal            EEG                                  FMRI                          MEG  EEG :- Electroencephalogram.                             FMRI:- Functional Magmatic                  Resonance imaging. MEG:- Magnetoencephalogram. The functional and physiological changes within brain can registered by EEG,MEG and FMRI.
The reasons of not using FMRI about using EEG,MEG Time resolution of FMRI image is very low (2 frames/sec).EEG bandwidth can be viewed using EEG or MEG signal. Many types of mental activities brain disorders cannot be registered using FMRI. Accessibility of FMRI systems is limited and costly.
EEG system consists of To convert from analog signal to digital signal:- 1) Sampling.      2) Quantization. 3) Encoding. Needle Electrodes Filters Amplifiers
Characteristics of EEG signal:- If data volume is increased then the number of bits increase. ,[object Object]
Minimum frequency 200 sample/sec.
Higher resolution (brain activities)=2000 sample/sec.               1 sample            16 bit Note
Note  Although the format of reading the EEG data may be different for different EEG machines, these formats are easily convertible to spreadsheets readable by most signal processing software packages such as MATLAB.
Different types of electrodes:- Disposable (gel-less, and pre-gelled types). Reusable dice electrodes (gold ,silver, stainless steel or tin). Headbands and electrode caps. Saline based electrodes. Needle electrodes. ,[object Object],[object Object]
Filters  Are used to make suitable for processing and visualization. Is divided to:- High pass filter:-                    remove distributing very low                   frequency components. 2) Low pass filter:-                   remove distributing very high                   frequency components.
Categories abnormal EEG patterns:- ,[object Object]
Bilateral persistent EEG.
Focal persistent EEG.,[object Object]

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Chapter (1) Introduction to EEG

  • 2. Agenda Introduction. History. Neural Activities. Action Potentials. EEG Generation. Brain Rhythms. EEG Recording and Measurement. Conditioning the Signals. Abnormal EEG Patterns. Ageing. Mental Disorders.
  • 3. Agenda Introduction. History. Neural Activities. Action Potentials. EEG Generation. Brain Rhythms. EEG Recording and Measurement. Conditioning the Signals. Abnormal EEG Patterns. Ageing. Mental Disorders.
  • 4. Introduction The human brain activity start between 4-5 months before parental development. The human brain represent the brain functional side to side the status of the whole body. EEG signals measured from the brain of a human. The medium defines the path from neurons, as so called signal sources to electro nodes which are the sensors.
  • 5. studying neural functions and neurophysicological properties of the brain together with the mechanisms underlying the generation of the signals for detection, diagnosis and treatment of brain disorders and the related diseases. Note :-
  • 6. Agenda Introduction. History. Neural Activities. Action Potentials. EEG Generation. Brain Rhythms. EEG Recording and Measurement. Conditioning the Signals. Abnormal EEG Patterns. Ageing. Mental Disorders.
  • 7. History Carlo Matteucci (1811–1868) and Emil Du Bois-Reymond (1818–1896) were the first people to register the electrical signals emitted from muscle nerves using a galvanometer and established the concept of neurophysiology. Analysis of EEG signals started during the early days of EEG measurement. Berger assisted by Dietch (1932) applied Fourier analysis to EEG sequences.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12. Transmits an electrical impulse and can be several meters long in vertebrates.
  • 13. In animals can be several meters but in humans the length can be a percentage of millimeter to a meter .
  • 14.
  • 15.
  • 16. Agenda Introduction. History. Neural Activities. Action Potentials. EEG Generation. Brain Rhythms. EEG Recording and Measurement. Conditioning the Signals. Abnormal EEG Patterns. Ageing. Mental Disorders.
  • 17.
  • 18. If an action potential travels along the fibre, which ends in an excitatory synapse, an excitatory postsynaptic potential (EPSP) occurs in the following neuron.
  • 19.
  • 20.
  • 21. Action Potentials (AP) APs are caused by an exchange of ions across the neuron membrane and an AP is a temporary change in the membrane potential that is transmitted along the axon. The conduction velocity of action potentials lies between 1 and 100 m/s. APs are initiated by many different types of stimuli; sensory nerves respond to many types of stimuli, such as chemical, light, electricity, pressure, touch, and stretching.
  • 22. Action potentials processes The action must be more than gate threshold value. Depolarization . Sodium gates close. 4. Potassium gates open. Repolarization. Hyperpolarization.
  • 23.
  • 24. Brain cells active mode (get a new action potential), the cell produced within dendrites so this current generate a magnetic field (EMG) that cover over scalp.
  • 25.
  • 26. When the human receive the action he could feel 1 % of the action, as it arrives to his brain and the other noise generated within scalp and skull.
  • 27. Therefore, to feel action potential there must be a lot of active neurons can generate potential.
  • 28.
  • 29. The amplitudes and frequencies of such signals change from one to another.
  • 30. This waves from low to high (alpha , theta, beta ,delta ,gamma)
  • 31. The history about found this frequencies.
  • 32.
  • 33. Agenda Introduction. History. Neural Activities. Action Potentials. EEG Generation. Brain Rhythms. EEG Recording and Measurement. Conditioning the Signals. Abnormal EEG Patterns. Ageing. Mental Disorders.
  • 34. EEG Recording and Measurement Signal EEG FMRI MEG EEG :- Electroencephalogram. FMRI:- Functional Magmatic Resonance imaging. MEG:- Magnetoencephalogram. The functional and physiological changes within brain can registered by EEG,MEG and FMRI.
  • 35. The reasons of not using FMRI about using EEG,MEG Time resolution of FMRI image is very low (2 frames/sec).EEG bandwidth can be viewed using EEG or MEG signal. Many types of mental activities brain disorders cannot be registered using FMRI. Accessibility of FMRI systems is limited and costly.
  • 36. EEG system consists of To convert from analog signal to digital signal:- 1) Sampling. 2) Quantization. 3) Encoding. Needle Electrodes Filters Amplifiers
  • 37.
  • 38.
  • 39. Minimum frequency 200 sample/sec.
  • 40. Higher resolution (brain activities)=2000 sample/sec. 1 sample 16 bit Note
  • 41. Note Although the format of reading the EEG data may be different for different EEG machines, these formats are easily convertible to spreadsheets readable by most signal processing software packages such as MATLAB.
  • 42.
  • 43. Filters Are used to make suitable for processing and visualization. Is divided to:- High pass filter:- remove distributing very low frequency components. 2) Low pass filter:- remove distributing very high frequency components.
  • 44.
  • 46.
  • 47. Agenda Introduction. History. Neural Activities. Action Potentials. EEG Generation. Brain Rhythms. EEG Recording and Measurement. Conditioning the Signals. Abnormal EEG Patterns. Ageing. Mental Disorders.
  • 48. Ageing The ageing process affects the normal cerebral activity in waking and sleep, and changes the response of the brain to stimuli. The charges stem from reducing the number of neurons and due to a general change in the brain pathology. General cause for ageing of brain may be decrease in cerebral blood flow. The REM duration decrease during the night. Dementia increases dramatically with ageing.  
  • 49. Agenda Introduction. History. Neural Activities. Action Potentials. EEG Generation. Brain Rhythms. EEG Recording and Measurement. Conditioning the Signals. Abnormal EEG Patterns. Ageing. Mental Disorders.
  • 50. Mental Disorders Is divided to Epileptic Seizure and No epileptic attacks Psychiatric Disorders Dementia External Effects
  • 51.
  • 52.
  • 53. Sub cortical dementias introduce less abnormality to the EEG patterns than the cortical ones.
  • 54.
  • 55.
  • 56. 4)External Effects EEG signal patterns may significantly change when using drugs for the treatment and suppression of various mental and CNS abnormalities. Variations in EEG patterns may also arise by just looking at the TV screen or listening to music without any attention. However, among the external effects the most significant ones are the pharmacological and drug effects. Therefore, it is important to know the effects of these drugs on the changes of EEG

Editor's Notes

  1. EEG or MEG (magneto encephalogram) machines may be integrated with other neuroimaging systems such as functional magnetic resonance imaging (fMRI).