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Chap13 Dokka

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Kartheek Dokka

The document discusses Syntaxin Ltd., a biotech company developing recombinant proteins derived from bacterial toxins to treat chronic lung diseases involving mucus hypersecretion. It describes testing of SXN187, a recombinant botulinum neurotoxin protein, on A549 lung cells, finding it reduced intracellular mucin retention in the cells. The goal is to develop a family of medicines using such proteins to inhibit secretion in diseases where it contributes to pathology, like COPD.

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Vesicular Transport Kartheek Kumar Dokka Chapter 13
Vesicular Transport
Budding and Fusion
Clathrin Coated Vesicles
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SNARES!!
Nerve Cell
How they move!
The Bacteria! The Neurotoxin: Botulinum
Botulinum Alert!
[object Object],[object Object],[object Object],[object Object],[object Object]
Effect of Botox ,[object Object]
$$$ for Allergan!
We are… ,[object Object],[object Object],[object Object],[object Object],[object Object]
What did we do… ,[object Object],[object Object],[object Object],[object Object]
What we got… ,[object Object],[object Object],[object Object],[object Object],Through this biotech research & development model Syntaxin aims to develop a family of medicines for chronic disorders where cell secretion is a major contributor to their pathology.
So basically….. ,[object Object],[object Object]
References! ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Chap13 Dokka