SlideShare una empresa de Scribd logo
1 de 26
Radiobiology A Preview By: Katherine Walz Callie Widmayer
Ionizing Radiation ,[object Object],http://www.paradigmlink.com/ionrad.shtml
Linear Energy Transfer (LET) ,[object Object],[object Object]
Low LET / High LET ,[object Object],[object Object],[object Object],[object Object],http://staff.jccc.net/PDECELL/biochemistry/dna.gif e -
Low LET / High LET ,[object Object],[object Object],[object Object],http://staff.jccc.net/PDECELL/biochemistry/dna.gif α ++
Ionizing Radiation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],The following are the most common types of ionizing radiation: http://www.paradigmlink.com/ionrad.shtml
Ionizing Radiation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],http://www.paradigmlink.com/ionrad.shtml
Ionizing Radiation ,[object Object],[object Object]
H 2 O HOH + e - water electron Positively charged water molecule Radiation reacts with water to produce an electron and a positively charged water molecule.
H 2 O HOH + e - + H 2 O HOH - water negatively charged water molecule electron water Positively charged water molecule The electron reacts with another water molecule to produce a negatively charged water molecule
H 2 O HOH + H + OH * e - + H 2 O HOH - water negatively charged water molecule Hydrogen ion Hydroxyl radical electron water Positively charged water molecule The positively charged water molecule dissociates into a hydrogen ion and a hydroxyl radical.
H 2 O HOH + H + OH * H * OH - e - + H 2 O HOH - water negatively charged water molecule Hydrogen ion Hydroxyl radical electron water Positively charged water molecule hydrogen radical Hydroxyl ion The negatively charged water molecule dissociates into a hydrogen radical and a hydroxyl ion.
Reactions ,[object Object],[object Object]
HOH +  +  e -  H 2 O The positively charged water molecule and the electron recombine to form water. H 2 O HOH + H + OH * H * OH - e - + H 2 O HOH -
H +   +  OH -   H 2 O The ions combine to form water. H 2 O HOH + H + OH * H * OH - e - + H 2 O HOH -
H *   +  OH *   H 2 O The radicals combine to form water. H 2 O HOH + H + OH * H * OH - e - + H 2 O HOH -
H 2 O HOH + H + OH * H * OH - e - + H 2 O HOH - OH* OH*  +  OH*  H 2 O 2 The hydroxyl radical reacts with another hydroxyl radical to form hydrogen peroxide.
Free Radicals ,[object Object],[object Object]
Direct Action / Indirect Action ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DNA Damage ,[object Object],[object Object],[object Object],[object Object]
http://www.greenfacts.org/glossary/def/dna.htm
Chromosome Aberrations ,[object Object],[object Object],[object Object],Translocation Inversion Deletion
Radiosensitivity ,[object Object],[object Object],[object Object]
Fractionation ,[object Object],[object Object],[object Object],http://www.usoncology.com/CompanyInfo/PhotoLibrary.asp
References ,[object Object],[object Object],[object Object],[object Object],[object Object]
References ,[object Object],[object Object],[object Object],[object Object],[object Object]

Más contenido relacionado

La actualidad más candente

radiation protection...Koustav Majumder....
radiation protection...Koustav Majumder....radiation protection...Koustav Majumder....
radiation protection...Koustav Majumder....
Koustav Majumder
 
Radiation oncology
Radiation oncologyRadiation oncology
Radiation oncology
Rad Tech
 

La actualidad más candente (20)

Quality Assurance in Radiotherapy and Dosimetry
Quality Assurance in Radiotherapy and DosimetryQuality Assurance in Radiotherapy and Dosimetry
Quality Assurance in Radiotherapy and Dosimetry
 
Lecture 4-Biological Effects of Ionizing Radiation
Lecture 4-Biological Effects of Ionizing RadiationLecture 4-Biological Effects of Ionizing Radiation
Lecture 4-Biological Effects of Ionizing Radiation
 
Radiobiology
RadiobiologyRadiobiology
Radiobiology
 
INTERACTION OF IONIZING RADIATION WITH MATTER
INTERACTION OF IONIZING RADIATION WITH MATTERINTERACTION OF IONIZING RADIATION WITH MATTER
INTERACTION OF IONIZING RADIATION WITH MATTER
 
TIME DOSE & FRACTIONATION
TIME DOSE & FRACTIONATIONTIME DOSE & FRACTIONATION
TIME DOSE & FRACTIONATION
 
Chap1 physics and chemistry of radiation absorption
Chap1 physics and chemistry of radiation absorptionChap1 physics and chemistry of radiation absorption
Chap1 physics and chemistry of radiation absorption
 
Radiation carcinogenesis
Radiation carcinogenesis Radiation carcinogenesis
Radiation carcinogenesis
 
Epid
EpidEpid
Epid
 
Intro of co 60 unit
Intro of co 60 unitIntro of co 60 unit
Intro of co 60 unit
 
Radiation cataractogenesis
Radiation cataractogenesisRadiation cataractogenesis
Radiation cataractogenesis
 
radIATION UNITS
radIATION UNITS radIATION UNITS
radIATION UNITS
 
radiation protection...Koustav Majumder....
radiation protection...Koustav Majumder....radiation protection...Koustav Majumder....
radiation protection...Koustav Majumder....
 
Radiation protection
Radiation protection   Radiation protection
Radiation protection
 
Radiation oncology
Radiation oncologyRadiation oncology
Radiation oncology
 
Cobalt & linac
Cobalt & linacCobalt & linac
Cobalt & linac
 
Thimble Ion chamber
Thimble Ion chamberThimble Ion chamber
Thimble Ion chamber
 
Principals of brachytherapy shk
Principals of brachytherapy shk Principals of brachytherapy shk
Principals of brachytherapy shk
 
EPID AND CBCT ON RADIATION THERAPY
EPID AND CBCT ON RADIATION THERAPYEPID AND CBCT ON RADIATION THERAPY
EPID AND CBCT ON RADIATION THERAPY
 
Radioisotopes and dose rates used for brachytherapy
Radioisotopes and dose rates used for brachytherapyRadioisotopes and dose rates used for brachytherapy
Radioisotopes and dose rates used for brachytherapy
 
BASICS RADIOBIOLOGY FOR RADIOTHERAPY
BASICS RADIOBIOLOGY FOR RADIOTHERAPYBASICS RADIOBIOLOGY FOR RADIOTHERAPY
BASICS RADIOBIOLOGY FOR RADIOTHERAPY
 

Destacado

Radiation therapy
Radiation therapyRadiation therapy
Radiation therapy
Rad Tech
 

Destacado (19)

Isotopic Teletherapy Machines
Isotopic Teletherapy MachinesIsotopic Teletherapy Machines
Isotopic Teletherapy Machines
 
Cancer Warning Signs
Cancer Warning SignsCancer Warning Signs
Cancer Warning Signs
 
Cancer
CancerCancer
Cancer
 
Cancer symptoms and treatment
Cancer symptoms and  treatmentCancer symptoms and  treatment
Cancer symptoms and treatment
 
Chemotherapy
ChemotherapyChemotherapy
Chemotherapy
 
Brachytherapy
BrachytherapyBrachytherapy
Brachytherapy
 
Cancer ppt
Cancer pptCancer ppt
Cancer ppt
 
Foundation of Radiotherapy (RT)
Foundation of Radiotherapy (RT)Foundation of Radiotherapy (RT)
Foundation of Radiotherapy (RT)
 
Radiation for Glioblastoma
Radiation for GlioblastomaRadiation for Glioblastoma
Radiation for Glioblastoma
 
Radiotherapy
RadiotherapyRadiotherapy
Radiotherapy
 
Radiation therapy
Radiation therapyRadiation therapy
Radiation therapy
 
New Techniques in Radiotherapy
New Techniques in RadiotherapyNew Techniques in Radiotherapy
New Techniques in Radiotherapy
 
Brain tumors 2
Brain tumors 2Brain tumors 2
Brain tumors 2
 
Radioisotopes
RadioisotopesRadioisotopes
Radioisotopes
 
Cancer Powerpoint
Cancer PowerpointCancer Powerpoint
Cancer Powerpoint
 
Uses of radioisotopes
Uses of radioisotopesUses of radioisotopes
Uses of radioisotopes
 
Radiation application
Radiation applicationRadiation application
Radiation application
 
Uses of radioisotopes
Uses of radioisotopesUses of radioisotopes
Uses of radioisotopes
 
Radiation therapy
Radiation therapyRadiation therapy
Radiation therapy
 

Similar a Radiation Therapy

Biological effects of ionizing radiations..what every physician must know
Biological effects of ionizing radiations..what every physician must knowBiological effects of ionizing radiations..what every physician must know
Biological effects of ionizing radiations..what every physician must know
Ahmed Bahnassy
 
Biologicaleffectsofionizingradiation
BiologicaleffectsofionizingradiationBiologicaleffectsofionizingradiation
Biologicaleffectsofionizingradiation
afzamalik
 
Linear energy transfer
Linear energy transferLinear energy transfer
Linear energy transfer
DeepaGautam
 
New Microsoft Office PowerPoint Presentation.pptx
New Microsoft Office PowerPoint Presentation.pptxNew Microsoft Office PowerPoint Presentation.pptx
New Microsoft Office PowerPoint Presentation.pptx
drjatin2
 
Biological effects of radiation
Biological effects of radiationBiological effects of radiation
Biological effects of radiation
DR.URVASHI NIKTE
 

Similar a Radiation Therapy (20)

Biological effects of ionizing radiations..what every physician must know
Biological effects of ionizing radiations..what every physician must knowBiological effects of ionizing radiations..what every physician must know
Biological effects of ionizing radiations..what every physician must know
 
Radiobiology- Basic Guide
Radiobiology- Basic Guide Radiobiology- Basic Guide
Radiobiology- Basic Guide
 
BIOLOGICAL BASIS OF RADIOTHERAPY
BIOLOGICAL BASIS OF RADIOTHERAPY BIOLOGICAL BASIS OF RADIOTHERAPY
BIOLOGICAL BASIS OF RADIOTHERAPY
 
Biologicaleffectsofionizingradiation
BiologicaleffectsofionizingradiationBiologicaleffectsofionizingradiation
Biologicaleffectsofionizingradiation
 
Biological effects of ionizing radiations
Biological effects of ionizing radiationsBiological effects of ionizing radiations
Biological effects of ionizing radiations
 
Mutation 2
Mutation 2Mutation 2
Mutation 2
 
Radiobiology Lec.ppt
Radiobiology Lec.pptRadiobiology Lec.ppt
Radiobiology Lec.ppt
 
Radiobiology for Clinical Oncologists, Introduction
Radiobiology for Clinical Oncologists, IntroductionRadiobiology for Clinical Oncologists, Introduction
Radiobiology for Clinical Oncologists, Introduction
 
Linear energy transfer
Linear energy transferLinear energy transfer
Linear energy transfer
 
Radiobiology
RadiobiologyRadiobiology
Radiobiology
 
radiation biology / dental implant courses by Indian dental academy 
radiation biology / dental implant courses by Indian dental academy radiation biology / dental implant courses by Indian dental academy 
radiation biology / dental implant courses by Indian dental academy 
 
Radiobiology -Physics and Chemistry of Radiation Absorption
Radiobiology -Physics and Chemistry of Radiation AbsorptionRadiobiology -Physics and Chemistry of Radiation Absorption
Radiobiology -Physics and Chemistry of Radiation Absorption
 
Radiation Biology
Radiation BiologyRadiation Biology
Radiation Biology
 
New Microsoft Office PowerPoint Presentation.pptx
New Microsoft Office PowerPoint Presentation.pptxNew Microsoft Office PowerPoint Presentation.pptx
New Microsoft Office PowerPoint Presentation.pptx
 
Oxidative stress
Oxidative stressOxidative stress
Oxidative stress
 
The Chemical Basis of Life
The Chemical Basis of LifeThe Chemical Basis of Life
The Chemical Basis of Life
 
Biological effects of radiation
Biological effects of radiationBiological effects of radiation
Biological effects of radiation
 
Ionizing radiation protection
Ionizing radiation protectionIonizing radiation protection
Ionizing radiation protection
 
Radioactivity & Radiopharmaceuticals Manik
Radioactivity & Radiopharmaceuticals ManikRadioactivity & Radiopharmaceuticals Manik
Radioactivity & Radiopharmaceuticals Manik
 
Radiation hazards in ortho
Radiation hazards in orthoRadiation hazards in ortho
Radiation hazards in ortho
 

Último

Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers:  A Deep Dive into Serverless Spatial Data and FMECloud Frontiers:  A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
Safe Software
 
Why Teams call analytics are critical to your entire business
Why Teams call analytics are critical to your entire businessWhy Teams call analytics are critical to your entire business
Why Teams call analytics are critical to your entire business
panagenda
 

Último (20)

AWS Community Day CPH - Three problems of Terraform
AWS Community Day CPH - Three problems of TerraformAWS Community Day CPH - Three problems of Terraform
AWS Community Day CPH - Three problems of Terraform
 
CNIC Information System with Pakdata Cf In Pakistan
CNIC Information System with Pakdata Cf In PakistanCNIC Information System with Pakdata Cf In Pakistan
CNIC Information System with Pakdata Cf In Pakistan
 
Boost Fertility New Invention Ups Success Rates.pdf
Boost Fertility New Invention Ups Success Rates.pdfBoost Fertility New Invention Ups Success Rates.pdf
Boost Fertility New Invention Ups Success Rates.pdf
 
Apidays New York 2024 - Accelerating FinTech Innovation by Vasa Krishnan, Fin...
Apidays New York 2024 - Accelerating FinTech Innovation by Vasa Krishnan, Fin...Apidays New York 2024 - Accelerating FinTech Innovation by Vasa Krishnan, Fin...
Apidays New York 2024 - Accelerating FinTech Innovation by Vasa Krishnan, Fin...
 
Apidays New York 2024 - The Good, the Bad and the Governed by David O'Neill, ...
Apidays New York 2024 - The Good, the Bad and the Governed by David O'Neill, ...Apidays New York 2024 - The Good, the Bad and the Governed by David O'Neill, ...
Apidays New York 2024 - The Good, the Bad and the Governed by David O'Neill, ...
 
ProductAnonymous-April2024-WinProductDiscovery-MelissaKlemke
ProductAnonymous-April2024-WinProductDiscovery-MelissaKlemkeProductAnonymous-April2024-WinProductDiscovery-MelissaKlemke
ProductAnonymous-April2024-WinProductDiscovery-MelissaKlemke
 
[BuildWithAI] Introduction to Gemini.pdf
[BuildWithAI] Introduction to Gemini.pdf[BuildWithAI] Introduction to Gemini.pdf
[BuildWithAI] Introduction to Gemini.pdf
 
Strategize a Smooth Tenant-to-tenant Migration and Copilot Takeoff
Strategize a Smooth Tenant-to-tenant Migration and Copilot TakeoffStrategize a Smooth Tenant-to-tenant Migration and Copilot Takeoff
Strategize a Smooth Tenant-to-tenant Migration and Copilot Takeoff
 
"I see eyes in my soup": How Delivery Hero implemented the safety system for ...
"I see eyes in my soup": How Delivery Hero implemented the safety system for ..."I see eyes in my soup": How Delivery Hero implemented the safety system for ...
"I see eyes in my soup": How Delivery Hero implemented the safety system for ...
 
TrustArc Webinar - Unlock the Power of AI-Driven Data Discovery
TrustArc Webinar - Unlock the Power of AI-Driven Data DiscoveryTrustArc Webinar - Unlock the Power of AI-Driven Data Discovery
TrustArc Webinar - Unlock the Power of AI-Driven Data Discovery
 
Platformless Horizons for Digital Adaptability
Platformless Horizons for Digital AdaptabilityPlatformless Horizons for Digital Adaptability
Platformless Horizons for Digital Adaptability
 
Understanding the FAA Part 107 License ..
Understanding the FAA Part 107 License ..Understanding the FAA Part 107 License ..
Understanding the FAA Part 107 License ..
 
presentation ICT roal in 21st century education
presentation ICT roal in 21st century educationpresentation ICT roal in 21st century education
presentation ICT roal in 21st century education
 
Exploring Multimodal Embeddings with Milvus
Exploring Multimodal Embeddings with MilvusExploring Multimodal Embeddings with Milvus
Exploring Multimodal Embeddings with Milvus
 
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers:  A Deep Dive into Serverless Spatial Data and FMECloud Frontiers:  A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
 
Corporate and higher education May webinar.pptx
Corporate and higher education May webinar.pptxCorporate and higher education May webinar.pptx
Corporate and higher education May webinar.pptx
 
Why Teams call analytics are critical to your entire business
Why Teams call analytics are critical to your entire businessWhy Teams call analytics are critical to your entire business
Why Teams call analytics are critical to your entire business
 
Vector Search -An Introduction in Oracle Database 23ai.pptx
Vector Search -An Introduction in Oracle Database 23ai.pptxVector Search -An Introduction in Oracle Database 23ai.pptx
Vector Search -An Introduction in Oracle Database 23ai.pptx
 
How to Troubleshoot Apps for the Modern Connected Worker
How to Troubleshoot Apps for the Modern Connected WorkerHow to Troubleshoot Apps for the Modern Connected Worker
How to Troubleshoot Apps for the Modern Connected Worker
 
Apidays New York 2024 - The value of a flexible API Management solution for O...
Apidays New York 2024 - The value of a flexible API Management solution for O...Apidays New York 2024 - The value of a flexible API Management solution for O...
Apidays New York 2024 - The value of a flexible API Management solution for O...
 

Radiation Therapy

  • 1. Radiobiology A Preview By: Katherine Walz Callie Widmayer
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9. H 2 O HOH + e - water electron Positively charged water molecule Radiation reacts with water to produce an electron and a positively charged water molecule.
  • 10. H 2 O HOH + e - + H 2 O HOH - water negatively charged water molecule electron water Positively charged water molecule The electron reacts with another water molecule to produce a negatively charged water molecule
  • 11. H 2 O HOH + H + OH * e - + H 2 O HOH - water negatively charged water molecule Hydrogen ion Hydroxyl radical electron water Positively charged water molecule The positively charged water molecule dissociates into a hydrogen ion and a hydroxyl radical.
  • 12. H 2 O HOH + H + OH * H * OH - e - + H 2 O HOH - water negatively charged water molecule Hydrogen ion Hydroxyl radical electron water Positively charged water molecule hydrogen radical Hydroxyl ion The negatively charged water molecule dissociates into a hydrogen radical and a hydroxyl ion.
  • 13.
  • 14. HOH + + e - H 2 O The positively charged water molecule and the electron recombine to form water. H 2 O HOH + H + OH * H * OH - e - + H 2 O HOH -
  • 15. H + + OH - H 2 O The ions combine to form water. H 2 O HOH + H + OH * H * OH - e - + H 2 O HOH -
  • 16. H * + OH * H 2 O The radicals combine to form water. H 2 O HOH + H + OH * H * OH - e - + H 2 O HOH -
  • 17. H 2 O HOH + H + OH * H * OH - e - + H 2 O HOH - OH* OH* + OH* H 2 O 2 The hydroxyl radical reacts with another hydroxyl radical to form hydrogen peroxide.
  • 18.
  • 19.
  • 20.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26.