1. Agnogenic myeloid metaplasia
Links : http://emedicine.medscape.com/article/197954-overview
http://www.diseasesdatabase.com/links1.asp?glngUserChoice=8616
"A chronic myeloproliferative disorder characterized by bone
marrow fibrosis, proliferation of atypical megakaryocytes and
granulocytes in the bone marrow, anemia, splenomegaly,
and extramedullary hematopoiesis. The cause is unknown.
The median survival time is 3-5 years from diagnosis. (WHO,
2001)"
"A partial or complete replacement of the bone marrow
stroma by fibrous tissue. It can be a primary bone marrow
lesion as part of the chronic myeloproliferative disorders
(chronic idiopathic myelofibrosis), a manifestation of
acute myeloid leukemia (acute panmyelosis with
myelofibrosis), or a secondary phenomenon due to bone
marrow involvement by a metastatic tumor (e.g.,
metastatic breast carcinoma). --2003"