The document discusses the global distribution and effects of AIDS. It notes that there are 42 million people worldwide living with HIV/AIDS, with 70% residing in sub-Saharan Africa. AIDS has already killed more than 14 million people in the region. The disease has more than doubled the death rate for people aged 15-34 in South Africa. Botswana's population structure is also expected to change dramatically in 20 years due to the high HIV prevalence rate of nearly 39% of the population. Lost income and medical costs from HIV/AIDS can have devastating economic impacts on families, especially when the main breadwinner is affected. Uganda has seen some success in reducing infections through aggressive public information campaigns.