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What are some genetic mutations and what is their affect?
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This ppt is prepared by Sandeep Kumar Maurya , m. pharma ,department of pharmaceutical sciences, dr. harisingh gour university sagar madhya pradesh. This SlideShare covers some of genetic disorders , molecular pathology, single gene disorder type of single gene disorder and advanced level cancer , mechanism of cancer, model for cancer induction explanation. 1. Introduction of genetic disorder 2. Common genetic disorders 3. Causes of genetic disorders 4. Symptoms of genetic disorders 5. single gene disorder 6. Cancer. 8. References. Genetic disorders occur when a mutation (a harmful change to a gene, also known as a pathogenic variant) affects your genes or when you have the wrong amount of genetic material. Genes are made of DNA (deoxyribonucleic acid), which contain instructions for cell functioning and the characteristics that make you unique. You receive half your genes from each biological parent and may inherit a gene mutation from one parent or both. Sometimes genes change due to issues within the DNA (mutations). This can raise your risk of having a genetic disorder. Some cause symptoms at birth, while others develop over time.` Introduction of Cancer Cancer is caused by the failure of genetic mechanisms that control the growth and proliferation of cells. In most cases, cumulative damage to multiple genes (the "multi-hit" model) via physical and chemical agents, replication errors, etc. contribute to oncogenesis. However, a person's inherited genetic background also may strongly contribute. In cancer, a single transformed cell grows to become a primary tumor, accumulates more mutations and becomes more aggressive, then metastasizes to another tissue and forms a secondary tumor. The difference between a benign tumor and a malignant one mostly involves the latter's ability to invade and metastasize to other tissues. Tumors are classified according to the embryonic origin of the tissue from which they originate. The term carcinoma is used to denote cancers of endodermal (e.g., gut epithelia cancers) or ectodermal (e.g., skin, neural epithelia) origin. Cancers of mesodermal origin (e.g., muscle, blood cells) are called sarcomas. Carcinomas make up >90% of malignant tumors.
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Chapter 3: The New Genetics Alma Villanueva, MA California State University, Los Angeles Overview Genetic Code The Beginning of Life Male & Female Twins Genotype & Phenotype Disorders Genetic Counseling Genetic Code Cells Basic unit of life Trillions! Nucleus Chromosomes Thread– like structures made up of DNA & protein 23 pairs DNA (Deoxyribonucleic acid) 2 strands twisted in a double helix Chemical composition of molecules that contain the genes Contains all of the information required to build/maintain the cell 3 Genes Small section of the chromosome 18,000 – 23,000 genes Each gene provides a unique recipe to make a protein 4 bases Code for your traits A - adenine T - thymine C - cytosine G – guanine Only 4 possible pairs A-T; T-A; C-G; G-C http://mybrainnotes.com/brain-dna-behavior.html 4 Allele A variation of a gene Example: the gene for eye color has several variations (alleles); an allele for blue eye color or an allele for brown eyes Everyone inherits alleles from sperm & ovum Genetic diversity Distinguishes each person Allows the human species to adapt to pressures of the environment Genome Full set of genes with instructions to make a living organism Genomes exist for each species Video about Genes 5 The Beginning of Life Two Parents, Millions of Gametes Gamete Reproductive cell Sperm or Ovum Each contains 23 pairs Zygote Cell formed with union of Sperm & Ovum Produce a new individual with 23 chromosomes from each parent Conception http://predictingbabygender.info/tag/intercourse-timing/ Matching genes Genotype Organism’s entire genetic inheritance, or genetic potential. Homozygous (same zygote) Two genes of one pair that are exactly the same in every letter of their code Heterozygous Two genes of one pair that differ in some way Usually not an issue Male of Female? Humans usually possess 46 chromosomes 44 autosomes and 2 sex chromosomes SEX chromosome = 23rd pair Female – XX Male – XY Mother’s contain X Father’s may have X or Y X chrom. Is larger & more genes Y contain SRY, making male hormones & organs It's a girl! Uncertain Sex “ambiguous genitals,” = child's sex is not abundantly clear a quick analysis of the chromosomes is needed, to make sure there are exactly 46 and to see whether the 23rd pair is XY or XX shown here a baby boy (left) and girl (right). Too Many Boys? Is sex selection the parents’ right or a social wrong? Preference for boys in many areas of world Ways to prevent female birth Inactivating X sperm before conception In vitro fertilization (IVF) Aborting XX fetuses My Strength, My Daughter slogan these girls in New Delhi are shouting at a demonstration against abortion of female fetuses in India The current sex ratio of children in India suggests that this campaign has not convinced every couple. New Cells Within hours of conception 23 pairs of chromosomes carrying all the genes duplicate, forming two complete sets of the genome Two sets ...
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What are drone anti-jamming systems? The drone anti-jamming systems and anti-spoof technology protect against interference, jamming, and spoofing of the UAVs. To protect their security, countries are beginning to research drone anti-jamming systems, also known as drone strike weapons. The anti-jam and anti-spoof technology protects against interference, jamming and spoofing. A drone strike weapon is a drone attack weapon that can attack and destroy enemy drones. So what is so unique about this amazing system?
What Are The Drone Anti-jamming Systems Technology?
What Are The Drone Anti-jamming Systems Technology?
Antenna Manufacturer Coco
How to get Oracle DBA Job as fresher.
Strategies for Landing an Oracle DBA Job as a Fresher
Strategies for Landing an Oracle DBA Job as a Fresher
Remote DBA Services
Finology Group – Insurtech Innovation Award 2024
Finology Group – Insurtech Innovation Award 2024
Finology Group – Insurtech Innovation Award 2024
The Digital Insurer
This presentations targets students or working professionals. You may know Google for search, YouTube, Android, Chrome, and Gmail, but did you know Google has many developer tools, platforms & APIs? This comprehensive yet still high-level overview outlines the most impactful tools for where to run your code, store & analyze your data. It will also inspire you as to what's possible. This talk is 50 minutes in length.
Powerful Google developer tools for immediate impact! (2023-24 C)
Powerful Google developer tools for immediate impact! (2023-24 C)
wesley chun
MySQL Webinar, presented on the 25th of April, 2024. Summary: MySQL solutions enable the deployment of diverse Database Architectures tailored to specific needs, including High Availability, Disaster Recovery, and Read Scale-Out. With MySQL Shell's AdminAPI, administrators can seamlessly set up, manage, and monitor these solutions, ensuring efficiency and ease of use in their administration. MySQL Router, on the other hand, provides transparent routing from the application traffic to the backend servers in the architectures, requiring minimal configuration. Completely built in-house and supported by Oracle, these solutions have been adopted by enterprises of all sizes for their business-critical applications. In this presentation, we'll delve into various database architecture solutions to help you choose the right one based on your business requirements. Focusing on technical details and the latest features to maximize the potential of these solutions.
Mastering MySQL Database Architecture: Deep Dive into MySQL Shell and MySQL R...
Mastering MySQL Database Architecture: Deep Dive into MySQL Shell and MySQL R...
Miguel Araújo
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Delhi Call girls
Presentation on how to chat with PDF using ChatGPT code interpreter
Presentation on how to chat with PDF using ChatGPT code interpreter
Presentation on how to chat with PDF using ChatGPT code interpreter
naman860154
Read about the journey the Adobe Experience Manager team has gone through in order to become and scale API-first throughout the organisation.
Scaling API-first – The story of a global engineering organization
Scaling API-first – The story of a global engineering organization
Radu Cotescu
My presentation at the Lehigh Carbon Community College (LCCC) NSA GenCyber Cyber Security Day event that is intended to foster an interest in the cyber security field amongst college students.
GenCyber Cyber Security Day Presentation
GenCyber Cyber Security Day Presentation
Michael W. Hawkins
Presentation on the progress in the Domino Container community project as delivered at the Engage 2024 conference
2024: Domino Containers - The Next Step. News from the Domino Container commu...
2024: Domino Containers - The Next Step. News from the Domino Container commu...
Martijn de Jong
Bajaj Allianz Life Insurance Company - Insurer Innovation Award 2024
Bajaj Allianz Life Insurance Company - Insurer Innovation Award 2024
Bajaj Allianz Life Insurance Company - Insurer Innovation Award 2024
The Digital Insurer
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Workshop - Best of Both Worlds_ Combine KG and Vector search for enhanced R...
Workshop - Best of Both Worlds_ Combine KG and Vector search for enhanced R...
Driving Behavioral Change for Information Management through Data-Driven Gree...
Driving Behavioral Change for Information Management through Data-Driven Gree...
IAC 2024 - IA Fast Track to Search Focused AI Solutions
IAC 2024 - IA Fast Track to Search Focused AI Solutions
Tech Trends Report 2024 Future Today Institute.pdf
Tech Trends Report 2024 Future Today Institute.pdf
Strategies for Unlocking Knowledge Management in Microsoft 365 in the Copilot...
Strategies for Unlocking Knowledge Management in Microsoft 365 in the Copilot...
Apidays Singapore 2024 - Building Digital Trust in a Digital Economy by Veron...
Apidays Singapore 2024 - Building Digital Trust in a Digital Economy by Veron...
From Event to Action: Accelerate Your Decision Making with Real-Time Automation
From Event to Action: Accelerate Your Decision Making with Real-Time Automation
How to Troubleshoot Apps for the Modern Connected Worker
How to Troubleshoot Apps for the Modern Connected Worker
What Are The Drone Anti-jamming Systems Technology?
What Are The Drone Anti-jamming Systems Technology?
Strategies for Landing an Oracle DBA Job as a Fresher
Strategies for Landing an Oracle DBA Job as a Fresher
Finology Group – Insurtech Innovation Award 2024
Finology Group – Insurtech Innovation Award 2024
Powerful Google developer tools for immediate impact! (2023-24 C)
Powerful Google developer tools for immediate impact! (2023-24 C)
Mastering MySQL Database Architecture: Deep Dive into MySQL Shell and MySQL R...
Mastering MySQL Database Architecture: Deep Dive into MySQL Shell and MySQL R...
08448380779 Call Girls In Friends Colony Women Seeking Men
08448380779 Call Girls In Friends Colony Women Seeking Men
Presentation on how to chat with PDF using ChatGPT code interpreter
Presentation on how to chat with PDF using ChatGPT code interpreter
Scaling API-first – The story of a global engineering organization
Scaling API-first – The story of a global engineering organization
GenCyber Cyber Security Day Presentation
GenCyber Cyber Security Day Presentation
2024: Domino Containers - The Next Step. News from the Domino Container commu...
2024: Domino Containers - The Next Step. News from the Domino Container commu...
Bajaj Allianz Life Insurance Company - Insurer Innovation Award 2024
Bajaj Allianz Life Insurance Company - Insurer Innovation Award 2024
Genetic Mutations
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There are MANY
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Not all Mutations
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Descargar ahora