Lipogenesis is the process by which fatty acids are synthesized from acetyl-CoA in the cytosol. Acetyl-CoA produced in mitochondria is transported to the cytosol via the citrate-malate shuttle. In the cytosol, acetyl-CoA and malonyl-ACP are condensed by fatty acid synthase to initiate the elongation cycle, which adds two carbon units in four steps utilizing NADPH. This cycle repeats until fatty acids of varying lengths are produced. Cholesterol synthesis is a 27 step process where acetyl-CoA is converted to mevalonate and then isopentenyl pyrophosphate, which condenses to form squalene and undergoes cyclization and