The MSDS for fluorescent DiI based liposomes used as a control for macrophage depletion studies.

1. ENCAPSULA NANOSCIENCES LLC
MATERIAL SAFTEY DATA SHEET
Date Created: 02/05/2013
1. PRODUCT AND COMPANY IDENTIFICATION
Product name: FLOURESCENT DII BASED LIPOSOMES IN PHOSPHATE BUFFERED
SALINE
Product number: FLR
Brand: FLUOROLIPOSOME®
Company Address: ENCAPSULA NANOSCIENCES LLC
441 DONELSON PIKE, SUITE 345
NASHVILLE, TN 37214, USA
Technical Phone: 615-884-4442
Fax: 615-250-8747
Emergency Phone: 615-438-8553
2. COMPOSITION/INFORMATION ON INGREDIENTS
Substance Name CAS# SARA313
FLUOROLIPOSOME NONE No
Ingredient Name CAS # Percent SARA313
WATER 7732-18-5 >90 No
SODIUM CHLORIDE 7647-14-5 <5 No
POTASSIUM CHLORIDE 7447-40-7 <5 No
DISODIUM PHOSPHATE 7558-79-4 <5 No
POTASSIUM PHOSPHATE 7758-11-4 <5 No
L-α-PHOSPHATIDYLCHOLINE 8002-43-5 <5 No
CHOLESTEROL 57-88-5 <5 No
Dil 41085-99-8 <5 No
3. HAZARDS IDENTIFICATION
HMIS RATING
FLUOROLIPOSOME www.clodrsome.com

2. ENCAPSULA NANOSCIENCES LLC
MATERIAL SAFTEY DATA SHEET
HEALTH: 0
FLAMMABILITY: 0
REACTIVITY: 0
NFPA RATING
HEALTH: 0
FLAMMABILITY: 0
REACTIVITY: 0
POTENTIAL HEALTH EFFECTS
Inhalation May be harmful if inhaled. May cause respiratory tract irritation.
Skin May be harmful if absorbed through skin. May cause skin irritation.
Eyes May cause eye irritation.
Ingestion: May be harmful if swallowed.
4. FIRST AID MEASURES
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is conscious. Call a
physician.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give artificial respiration. If
breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of contact, immediately wash skin with soap and copious amounts of
water.
EYE EXPOSURE
In case of contact, immediately flush eyes with copious amounts of water for at
least 15 minutes.
5. FIRE FIGHTING MEASURES
FLASH POINT
N/A
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA

3. ENCAPSULA NANOSCIENCES LLC
MATERIAL SAFTEY DATA SHEET
Suitable: Water spray. Carbon dioxide, dry chemical powder, or appropriate
foam.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus and protective
clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
6. ACCIDENTAL RELEASE MEASURES
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for disposal.
Ventilate area and wash spill site after material pickup is complete.
7. HANDLING AND STORAGE
HANDALING
User Exposure: Do not breathe vapor. Do not get in eyes, on skin, on clothing.
STORAGE
Suitable: Keep tightly closed under an inert gas. Store in refrigerator at 4 °C.
8. EXPOSURE CONTROLS/ PERSONAL PROTECTION
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Use respirators and components tested and approved under
appropriate government standards such as NIOSH (US) or CEN (EU).
Respiratory protection is not required. Where protection is desired, use multi
purpose combination (US) or type ABEK (EN 14387) respirator cartridges.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before reuse.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
Pink liquid dispersion
Safety data
pH 7.4

4. ENCAPSULA NANOSCIENCES LLC
MATERIAL SAFTEY DATA SHEET
Melting point
N/A
Boiling point
N/A
Flash point
N/A
Ignition temperature
N/A
Lower explosion limit
N/A
Upper explosion limit
N/A
Water solubility
N/A
10. STABILTIY AND REACTIVITY
Storage stability
Can be stored for one month under nitrogen or argon at 4 °C.
Materials to avoid
Strong acids, Strong bases
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. – Carbon
oxides, Oxides of phosphorus, Hydrogen chloride gas, Sodium oxides
11. TOXICOLOGICAL INFORMATION
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and upper respiratory
tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and toxicological
properties have not been thoroughly investigated.
12. ECOLOGICAL INFORMATION

5. ENCAPSULA NANOSCIENCES LLC
MATERIAL SAFTEY DATA SHEET
Elimination information (persistence and degradability)
N/A
Ecotoxicity effects
N/A
Further information on ecology
N/A
13. DISPOSAL CONCIDERATIONS
Product
Observe all federal, state, and local environmental regulations.
Contaminated packaging
Dispose of as unused product.
14. TRANSPORT INFORMATION
DOT (US)
Not dangerous goods
IMDG
Not dangerous goods
IATA
Not dangerous goods
15. REGULATORY INFORMATION
OSHA Hazards
No OSHA HAZARD
DSL Status
All components of this product are on the Canadian DSL list.
SARA 302 Components
SARA 302: No chemicals in this material are subject to the reporting
requirements of SARA Title III, Section 302.
SARA 313 Components
SARA 313: This material does not contain any chemical components with
known CAS numbers that exceed the threshold (De Minimis) reporting levels
established by SARA Title III, Section 313.
SARA 311/312 Hazards
NO SARA HAZARD
Massachusetts Right To Know Components

6. ENCAPSULA NANOSCIENCES LLC
MATERIAL SAFTEY DATA SHEET
No components are subject to the Massachusetts Right to Know Act.
Pennsylvania Right To Know Components
Lecithin AKA L-α-Phosphatidylcholine CAS-No. 8002-43-5 Revision Date:
Cholesterol CAS-No. 55-88-5 Revision Date:
Dil CAS-No. 41085-99-8 Revision Date:
New Jersey Right To Know Components
Lecithin AKA L-α-Phosphatidylcholine CAS-No. 8002-43-5 Revision Date:
Cholesterol CAS-No. 55-88-5 Revision Date:
Dil CAS-No. 41085-99-8 Revision Date:
California Prop. 65 Components
This product does not contain any chemicals known to State of California to
cause cancer, birth, or any other reproductive defects.
16. OTHER INFORMATION
Further information
Copyright 2009 Encapsula NanoSciences LLC license granted to make unlimited
paper copies for internal use only.
The above information is believed to be correct but does not purport to be all
inclusive and shall be used only as a guide. The information in this document is
based on the present state of our knowledge and is applicable to the product
with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Encapsula NanoSciences LLC shall
not be held liable for any damage resulting from handling or from contact with
the above product.