Ganoderma Lucidum

Luigi Leung 80171899 Lingzhi ( Ganoderma Lucidum )

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Area of Origin ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Area of Origin Isolated Ganoderma Ganoderma in natural habitat Shennong (aka. Yan Emperor) (aka. Father of Chinese agriculture)

Current Area of Cultivation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Current Area of Cultivation Wood log cultivation Pot or bottle cultivation Tank (box) cultivation

Historical Significance/Usage ,[object Object],[object Object],[object Object]

Current Significance ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Current Significance Fig. 3. Induction of G2/M arrest in HL-60 cells by G. lucidum extract. Panel a shows cell cycle analysis by flow cytometry after PI staining for untreated control cells. Panel b depicts cell cycle analysis for cells treated with G. lucidum , 100 μg/ml for 72 h. Increasing number of HL-60 cells in the G2/M phase of the cell cycle were detected. Horizontal and vertical axis represent DNA content and cell number, respectively. Percentages of the different cell cycle phases are calculated for the population of cells within the dashed lines. Representative of one of two experiments with similar results. Müller, Claudia I., et al. “Ganoderma lucidum causes apoptosis in leukemia, lymphoma and multiple myeloma cells.” Leukemia Research 30.7 (June 2006): 841-848. ,[object Object],[object Object],[object Object]

Current Significance Fig. 2. Growth arrest of hematologic cell lines induced by G. lucidum extract. Cells included: panel a, acute myeloid leukemia (HL-60, U937); panel b, erythroid chronic myeloid leukemia (K562); panel c, acute lymphoblastic leukemia (Blin-1, Nalm-6); panel d, multiple myeloma (RPMI8226). Cells of each line were treated with G. lucidum (10, 20, 40, 60, 80 and 100 μ g/mg) for 96 h. MTT assay was performed. Viable cells were expressed as a percentage of untreated control cultures for each line. Results represent the mean ± S.D. of three different experiments performed in triplicates. ,[object Object],[object Object],[object Object]

Components Major components found in Ganoderma Lucidum ,[object Object],[object Object],2 Lee, JH., et al. “Anti-inflammatory effect of germanium-concentrated yeast against paw oedema is related to the inhibition of arachidonic acid release and prostaglandin E production in RBL 2H3 cells.” Auton Autacoid Pharmacol. 25.4 (Oct 2005): 129-134. 1 Tao, SH., Bolger, PM. “Hazard Assessment of Germanium Supplements.” Regulatory Toxicol. and Pharmacol. 25.3 (Jun 1997): 211-219. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

“ Old Wives” Tales ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Bibliography ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Ganoderma Lucidum

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