11. • Isaac Newton.
1666 • “Colors phenomenon”
• William Herschel.
1800
• Infrared radiation
• Johann Ritter.
1801 • Ultraviolet radiation
Diffey B. Methods. 2002; 28: 4-13
12. Ultraviolet light or
ultraviolet
radiation?
“beyond violet”
Exposure to UV and
its several sequellae
◦ 1932 Copenhaguen
UVC
Maverakis E, et al. Journal of Autoimmunity. 2010; 34: 47-57
29. Outdoor
activities
UV artificial
sources
Ozone layer
An estimaded 3.5 millions of new cases each year in USA. 1/5 during
lifetime. The most common skin cancer.
Camp et al. Semin Cutan Med Surg. 2011; 30: 6-13
30. Most common cancer in humans
3-8% of annual increase since 1960
Firm association with UV exposure
40 -50% recurrent CBC
80% older than 60 year
Madan V, Lear J, Szeimies R. Lancet. 2010; 375:373-85
32. Annual incidence
3-7% increase More related with
7.89 to 22.52
since 1970 mortality
for each 100000
Kanavy H, Gerstenblith M. Seminars in cutaneous Medicine and surgery. 2011; 222-8
33.
34. Melanoma geographical distribution is bigger next to this
area. 1% decrease in ozone layer increase melanoma
mortality 1-2%.
Kanavy H, Gerstenblith M. Seminars in cutaneous Medicine and surgery. 2011; 222-8
41. Sunscreens are photochemical systems that
absorb or reflect UV radiation.
Frequently use of sunscreens is the best
photoprotection strategy.
The first sunscreen was marketed in 1930
Actually there are 28 chemical filters in
Australia, 26 in Europe and 14 in USA.
Kockler J, Oelgemoller M, Robertson S, Glass B.
Journal of Photochemistry and Photobiology. 2012; 1-17
42. UVR
Dispersion
Absorption
Reflection
Chemical or physical filters
43. La capacidad de eritema depende
◦ Longitud de onda de radiación
◦ Fotosensibilidad del individuo
◦ DEM uso estudios observacionales
MED protected
SPF = ----------------
MED
unprotected
Kockler J, Oelgemoller M, Robertson S, Glass B.
Journal of Photochemistry and Photobiology. 2012; 1-17
44. La capacidad de eritema depende
◦ Longitud de onda de radiación
◦ Fotosensibilidad del individuo
◦ DEM uso estudios observacionales
MPD protected
UVA FP = ----------------
MPD
unprotected
DPM: dosis de pigmento mínima
Kockler J, Oelgemoller M, Robertson S, Glass B.
Journal of Photochemistry and Photobiology. 2012; 1-17
45. FILTROS ACCIÓN ESPECTRO
INORGÁNICOS- FÍSICOS
Dióxido de titanio al 25% 350 UVA, UVB
Óxido de cinc al 25% 350 UVA, UVB
ORGÁNICOS - QUÍMICOS
Filtros para UVA
Benzofenonas
Oxibenzonas al 6% 288-325 UVB, UVA II
Sulisobenzonas al 10% 366 UVA
Dioxibenzona al 3% 352 UVA
Dibenzolimetanos
Avobenzona 3% 360 UVA1
Antralatos
Medalimato al 3% 340 UVAII
Ecamsul (mexorilo SX) 345 UVB, UVA
Ácido terephtalilideno
diaalcanforsulfínico al 10%
46. FILTROS ACCIÓN ESPECTRO
Filtros para UVB
Aminobenzoatos (derivados del PABA)
PABA al 1 5% 283 UVB
Padimato O (octil dimetil PABA) al 8% 311 UVB
Cinamatos
Cinoxato al 3% 289 UVB
Octinoxate (octil metoxicinamato) al 7.5% 311 UVB
Salicilatos
Octilsalate (octil salicilato) al 5% 307 UVB
Homosalat (homentil salicilato) al 15% 306 UVB
Trolamina salicilato al 12% 306 UVB
Otros
Octocrileno al 10% 303 UVB, UVAII
Ensulizolo al 4% 310
Metileno-bis-benzotriazolila 305- UVB, UVA
Tetrametilbutifenol (Tinosorb M) al 10% 360 Filtro inorgánico y orgánico
Bis-etilhexiloxifenol metoxifenil triazina 310-
(Tinosorb S) al 10% 340
Moreno M, Moreno L. Rev Asoc Colomb Dermatol. 2009; 10: 1-9
47. SPF 30 (97.5 UVB)
◦ 370nm
High UVA protection
20 min before and 2 - 3
hours
SPF 30
UVA high
protection
48. 50- 80% solar damage is
Correct solar protection
before 18
Walker D. Journal of Pediatric nursing. 2011 Article in press