6. N e u r o p r a x i a Mildest form, reversible conduction block (function loss), for hours or days due to direct mechanical compression, ischemia, mild burn trauma or stretch
7. A x o n t m e s i s Axonal and myelin sheath disruption while fascicular integrity is maintained--Wallerian degeneration occurs (prognosis is good—days, weeks)
8. N e u r o t m e s i s Laceration from sharp or blunt forces causing complete disruption of the axon and supporting connective tissue---very poor prognosis without surgical repair
9.
10.
11. C l i n i c a l S i g n s Motor function, Tinel’s sign (positive-sensory function negative (after 4-6weeks)-total interruption, Sweating-sympathetic fiber, Sensory function
13. C h r o n i c N e r v e E n t r a p m e n t Paresthesia Loss of function Pain
14. P a t h o p h y s i o l o g y Direct compression Segmental demyelination Wallerian degeneration(distal) Ischemia Swelling of nerve Microcompartment SD
37. C o n s e r v a t i v e t r e a t m e n t Indications Short history, mild-moderate, intermittent, reversible cause (pregnancy, oral contraceptive, endocrine abnormalities, type writer) Method Non-steroidal anti-inflammatory drugs, splint
38. T r e a t m e n t Time of operation Open injury Closed injury Early intervention Delayed intervention Delayed intervention
39. S u r g i c a l I n d i c a t i o n s Failed conservative treatment Severe injury (sensory loss, muscle atrophy, motor weakness)