1. © 2003 Simone Protective Pharmaceuticals

2. During your life, there are people you would like to meet….and there are people you should meet. Meet now Dr. Charles B. Simone, who is a Medical Oncologist, Immunologist, and Radiation Oncologist. He trained in Internal Medicine at the Cleveland Clinic, then trained as a Medical Oncologist and Tumor Immunologist at the National Cancer Institute in Bethesda, MD. At the University of Pennsylvania in Philadelphia he continued his training as a Radiation Oncologist.

3. Dr. Simone writes many books including Cancer and Nutrition, and The Truth About Breast Health – Breast Cancer . Dr. Simone has been intensely involved in nutrition since 1981. Dr. Simone has worked in cancer research and treatment since 1976. He is the Founder of the Simone Protective Cancer Center.

4. He is called upon to testify in the United States Senate and Congress about nutrition, cancer, health care and FDA issues. Dr. Simone is a consultant to heads of state and celebrities and has appeared on 60 Minutes, Primetime Live, Fox News Channel, and numerous other TV and radio shows. Now please meet Dr. Charles B. Simone.

5. Muscle Cramping and Pain are major enemies of an athlete.

6. Nothing is more frustrating to a highly conditioned athlete than being unable to continue a competition because of cramping and fatigue.

7. Now there is a solution. It’s an amazing new nutritional formula called

8. CRAMPING, FATIGUE , PHYSICAL EXHAUSTION and DEHYDRATION result from exercise causing the depletion of sugars, electrolytes, amino acids, vitamins, minerals, and water – SIMONE SUPER ENERGY , Scientific Leader , replaces these.* * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

9. Hello, I’m Dr. Charles B. Simone, and I would like to provide you with factual information about dehydration that can lead to cellular death, fatigue, and make you aware of the many myths surrounding sports activity drinks. Charles B. Simone, M.D.

10. Athletes,

11. people in deserts,

12. or people doing strenuous physical activity

13. can lose 1 - 2 liters of sweat per hour – that’s 8 - 17 ounces every 15 minutes.

14. And they can lose up to 4 liters per hour if they wear heavy clothing on a hot day.

15. I was asked to create a comprehensive nutritional formula that would address the issues of exercise induced cramping, fatigue, and also hydration.

16. I examined my personal experiences from investigating extremely hot climates, like the Grand Canyon,

17. deserts,

18. and the jungle, and also from treating cancer patients – 75% have fatigue, and 40% die from malnutrition and dehydration.

20. I applied my scientific and extensive medical training to develop SIMONE SUPER ENERGY drink formula.

21. Muscle Nerve Neuromuscular Junction This was done by researching and understanding the physiological and nutritional needs of the

22. The problem with some sports activity drinks is that they have high levels of sodium, reflecting the widely held fallacy that strenuous activity calls for salt. This is wrong and potentially dangerous.

24. The orange flavored SIMONE SUPER ENERGY has an osmolality of less than 265, and therefore gets quickly absorbed into the bloodstream. Drinks that have osmolalities greater than 330 are slowly absorbed.

25. Muscle Nerve Neuromuscular Junction I will now review with you the findings of my medical and scientific research regarding the most effective and optimum nutritional needs of the

26. Muscle EXERCISE causes: FREE RADICALS to form that damage your muscles LACTIC ACID and AMMONIA accumulation causing pain in your muscles that limits your performance. Let’s first talk about the muscle

27. Muscles Need: Antioxidants Lactic Acid Neutralizers Ammonia Neutralizers Nutrients Proper Electrolytes Amino Acids Energy, Oxygen, Water

28. Next, the Nerve It transmits information from the brain to the muscle The NERVE NEEDS Antioxidants Proper Electrolytes Vitamins, Minerals C alcium Energy, Oxygen, Water

29. Muscle Nerve Neuromuscular Junction is composed of To transmit information efficiently • The membranes must be stabilized • The junction must be cleaned often and • Neuromuscular enhancing molecules are needed

30. NEUROMUSCULAR JUNCTION Membranes must be stabilized Junction must be cleaned Antioxidants Electrolytes Amino Acids Vitamins Minerals Calcium Energy, O 2 , H 2 O Antioxidants Electrolytes Amino Acids Vitamins, Minerals Energy, O 2 , H 2 O Neutralizers for: Lactic Acid Ammonia Nutrient Needs of Neuro-Muscular Complex Muscle Nerve

31. Knowing the scientific facts, SIMONE SUPER ENERGY was created. SIMONE SUPER ENERGY has the Essential Factors that makes it a QUALITY FORMULA AND PUTS IT IN A CLASS OF ITS OWN MAKING IT A SCIENTIFIC LEADER.

32. LOW HIGH Potassium >330 <300 Osmolality 0 YES Membrane Stabilizers 0 YES Methyl Donors 0 YES Ammonia Neutralizers 0 YES Lactic Acid Neutralizers 0 YES Muscle Enhancers 0 YES Nerve Enhancers 0 YES Energy Enhancers 0 YES Amino Acids 0 YES Antioxidants 0 100% Vitamins HIGH LOW Sodium 0 1 gm Protein Others Simone Super Energy Factor

33. Clean membranes to optimize transport of cellular materials Membrane Stabilizers Essential for muscle performance Methyl Donors Neutralize harmful build-up in muscles that impede performance Lactic Acid and Ammonia Neutralizers Provide efficient communication between nerve and muscle Nerve and Muscle Enhancers Allow efficient use of energy source Energy Enhancers Essential muscle building blocks Amino Acids Neutralize Free Radicals generated by muscle Antioxidants Replace all daily vitamins Vitamins 100% The proper ratio is critical for function Sodium & Potassium Essential for the body and muscles Protein Function Factor

34. SIMONE SUPER ENERGY is truly in a Class of its Own Patented in many countries International Olympic Committee International Athletic Federation National Collegiate Athletic Assoc. USA Track and Field, NFL

35. SIMONE SUPER ENERGY is successfully used by World Class Athletes and successfully used in the harsh conditions of the North African desert. It is a healthy nutritional drink that provides These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

36. SIMONE SUPER ENERGY is a perfect nutritional product. Some drinks are nothing more than salt, sugar, and water.

37. SIMONE SUPER ENERGY is successfully used by some World Class, Professional, and amateur athletes, as well as people in everyday activities, and those seeking better health and fitness.

38. SIMONE SUPER ENERGY is a real quality drink that you deserve because you will FEEL THE DIFFERENCE and your body will feel the difference. Once you FEEL THE DIFFERENCE, YOU WILL MAKE A DIFFERENCE . Thank you for taking the time to review this information about SIMONE SUPER ENERGY .