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SAFS GSS Nov 2008: Characterization of prostaglandins in the Pacific oyster Crassostrea gigas: evidence for a role in immune response

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School of Aquatic & Fishery Sciences Graduate Student Symposium

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Characterization of prostaglandins in the Pacific oyster Crassostrea gigas : evidence for a role in immune response Mackenzie Gavery, M.S. Student Roberts Lab
Molecules with Diverse Functions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Molecules with Diverse Functions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Roberts et al
What are prostaglandins? ,[object Object],[object Object],[object Object]
Arachidonic Acid Cascade PGE receptor
Outline ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Arachidonic Acid Cascade PGE receptor
Sequences PGE receptor ESTs: snail, mussel ,[object Object],[object Object],ESTs: ongoing ,[object Object],[object Object]
Data PGE receptor
Full-length Sequence PGE receptor ,[object Object],[object Object],[object Object],[object Object]
COX Gene Similarities
Outline ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Experiments ,[object Object],[object Object]
Analytical Results ,[object Object],[object Object],PGE receptor
Vibrio exposure-ELISA results PGE conjugate PGE sample 100% 0%
Gill Tissue/Vibrio– qPCR PGE receptor
Plated hemocytes/Vibrio - qPCR
Outline ,[object Object],[object Object],[object Object],[object Object]
Applied Research ,[object Object],[object Object],[object Object],[object Object],[object Object],temperature pathogen exposure acidification pesticides
Applied Research ,[object Object],[object Object],[object Object],[object Object]
Acknowledgements ,[object Object],[object Object],[object Object]

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SAFS GSS Nov 2008: Characterization of prostaglandins in the Pacific oyster Crassostrea gigas: evidence for a role in immune response