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5-Cyanoindole (cas 15861-24-2) MSDS
      1.     IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
      1.1    Product identifiers
             Product name                     :   Indole-5-carbonitrile
             Product Number                   :   C92006
             Brand                            :
             CAS-No.                        15861-24-2
                                              :
      1.2    Relevant identified uses of the substance or mixture and uses advised against
             Identified uses                  :   Laboratory chemicals, Manufacture of substances
      2.     HAZARDS IDENTIFICATION
      2.1    Classification of the substance or mixture
             Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
             Skin irritation (Category 2)
             Eye irritation (Category 2)
             Specific target organ toxicity - single exposure (Category 3)
             Classification according to EU Directives 67/548/EEC or 1999/45/EC
             Irritating to eyes, respiratory system and skin.
      2.2    Label elements
             Labelling according Regulation (EC) No 1272/2008 [CLP]
             Pictogram

             Signal word                          Warning
             Hazard statement(s)
             H315                                 Causes skin irritation.
             H319                                 Causes serious eye irritation.
             H335                                 May cause respiratory irritation.
             Precautionary statement(s)
             P261                                 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
             P305 + P351 + P338                   IF IN EYES: Rinse cautiously with water for several minutes. Remove
                                                  contact lenses, if present and easy to do. Continue rinsing.
      - C92006
             Supplemental Hazard                  none
             Statements
             According to European Directive 67/548/EEC as amended.
             Hazard symbol(s)


             R-phrase(s)
             R36/37/38                            Irritating to eyes, respiratory system and skin.
             S-phrase(s)
             S26                                  In case of contact with eyes, rinse immediately with plenty of water and
                                                  seek medical advice.
             S36                                  Wear suitable protective clothing.
      2.3    Other hazards - none
      3.     COMPOSITION/INFORMATION ON INGREDIENTS
      3.1    Substances
             Synonyms             : 5-cyanoindole

             Formula                          :   C9H6N2
             Molecular Weight                 :   142,16 g/mol
             Component                                                                                        Concentration
             Indole-5-carbonitrile
CAS-No.                      15861-24-2                                                      -
             EC-No.                       239-986-4


4.     FIRST AID MEASURES
4.1    Description of first aid measures
       General advice
       Consult a physician. Show this safety data sheet to the doctor in attendance.
       If inhaled
       If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
       In case of skin contact
       Wash off with soap and plenty of water. Consult a physician.
       In case of eye contact
       Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
       If swallowed
       Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2    Most important symptoms and effects, both acute and delayed
       To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly
       investigated.
4.3    Indication of any immediate medical attention and special treatment needed
       no data available

5.     FIREFIGHTING MEASURES
5.1    Extinguishing media
       Suitable extinguishing media
       Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.


- C92006
5.2    Special hazards arising from the substance or mixture
       Carbon oxides, nitrogen oxides (NOx)
5.3    Advice for firefighters
       Wear self contained breathing apparatus for fire fighting if necessary.
5.4    Further information
       no data available

6.     ACCIDENTAL RELEASE MEASURES
6.1    Personal precautions, protective equipment and emergency procedures
       Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure
       adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
6.2    Environmental precautions
       Do not let product enter drains.
6.3    Methods and materials for containment and cleaning up
       Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
       containers for disposal.
6.4    Reference to other sections
       For disposal see section 13.

7.     HANDLING AND STORAGE
7.1    Precautions for safe handling
       Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
       Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire
       protection.
7.2    Conditions for safe storage, including any incompatibilities
       Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
       Light sensitive.
7.3    Specific end uses
       no data available

8.     EXPOSURE CONTROLS/PERSONAL PROTECTION
8.1    Control parameters
       Components with workplace control parameters
8.2    Exposure controls
Appropriate engineering controls
       Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at
       the end of workday.
       Personal protective equipment
            Eye/face protection
             Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and
             approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
             Skin protection
             Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
             (without touching glove's outer surface) to avoid skin contact with this product. Dispose of
             contaminated gloves after use in accordance with applicable laws and good laboratory practices.
             Wash and dry hands.
             The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the
             standard EN 374 derived from it.


- C92006
             Body Protection
             impervious clothing, The type of protective equipment must be selected according to the
             concentration and amount of the dangerous substance at the specific workplace.
             Respiratory protection
             For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher
             level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use
             respirators and components tested and approved under appropriate government standards such as
             NIOSH (US) or CEN (EU).

9.     PHYSICAL AND CHEMICAL PROPERTIES
9.1    Information on basic physical and chemical properties
       a) Appearance                  Form: crystalline
                                      Colour: beige
       b) Odour                       no data available
       c) Odour Threshold             no data available
       d) pH                          no data available
       e) Melting point/freezing      Melting point/range: 106 - 108 °C - lit.
          point
       f) Initial boiling point and   no data available
          boiling range
       g) Flash point                 no data available
       h) Evaporation rate            no data available
       i)   Flammability (solid, gas) no data available
       j)   Upper/lower                no data available
            flammability or
            explosive limits
       k) Vapour pressure             no data available
       l) Vapour density              no data available
       m) Relative density            no data available
       n) Water solubility            no data available
       o) Partition coefficient: n-   no data available
          octanol/water
       p) Autoignition                no data available
          temperature
       q) Decomposition               no data available
          temperature
       r) Viscosity                   no data available
       s) Explosive properties        no data available
       t) Oxidizing properties        no data available
9.2    Other safety information
       no data available

10. STABILITY AND REACTIVITY
10.1 Reactivity
       no data available
10.2 Chemical stability
       no data available
- C92006
10.3 Possibility of hazardous reactions
       no data available
10.4 Conditions to avoid
       no data available
10.5 Incompatible materials
       Strong oxidizing agents, Strong acids, Strong bases
10.6 Hazardous decomposition products
       Other decomposition products - no data available

11. TOXICOLOGICAL INFORMATION
11.1 Information on toxicological effects
     Acute toxicity
       LD50 Intravenous - mouse - 100 mg/kg
       Skin corrosion/irritation
       no data available
       Serious eye damage/eye irritation
       no data available
       Respiratory or skin sensitization
       no data available
       Germ cell mutagenicity
       no data available
       Carcinogenicity
       IARC:        No component of this product present at levels greater than or equal to 0.1% is identified as
                    probable, possible or confirmed human carcinogen by IARC.
       Reproductive toxicity
       no data available
       Specific target organ toxicity - single exposure
       Inhalation - May cause respiratory irritation.
       Specific target organ toxicity - repeated exposure
       no data available
       Aspiration hazard
       no data available
       Potential health effects
            Inhalation          May be harmful if inhaled. Causes respiratory tract irritation.
            Ingestion           May be harmful if swallowed.
            Skin                May be harmful if absorbed through skin. Causes skin irritation.
            Eyes                Causes serious eye irritation.
       Signs and Symptoms of Exposure
       To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly
       investigated.
       Additional Information
       RTECS: NL5993120

12. ECOLOGICAL INFORMATION
12.1 Toxicity
       no data available
12.2 Persistence and degradability
       no data available
- C92006
12.3 Bioaccumulative potential
       no data available
12.4 Mobility in soil
       no data available
12.5 Results of PBT and vPvB assessment
       no data available
12.6 Other adverse effects
       no data available
13. DISPOSAL CONSIDERATIONS
13.1 Waste treatment methods
     Product
      Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional
      waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent
      and burn in a chemical incinerator equipped with an afterburner and scrubber.
      Contaminated packaging
      Dispose of as unused product.

14. TRANSPORT INFORMATION
14.1 UN number
      ADR/RID: -                          IMDG: -                              IATA: -
14.2 UN proper shipping name
      ADR/RID: Not dangerous goods
      IMDG:    Not dangerous goods
      IATA:    Not dangerous goods
14.3 Transport hazard class(es)
      ADR/RID: -                          IMDG: -                              IATA: -
14.4 Packaging group
      ADR/RID: -                          IMDG: -                              IATA: -
14.5 Environmental hazards
      ADR/RID: no                         IMDG Marine pollutant: no            IATA: no
14.6 Special precautions for user
      no data available

15.   REGULATORY INFORMATION
      This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
      no data available
15.2 Chemical Safety Assessment
      no data available

16.   OTHER INFORMATION
      Further information
      The above information is believed to be correct but does not purport to be all inclusive and
      shall be used only as a guide. The information this document is based on the resent state
      of our knowledge and is applicable to the product with regard to appropriate safety precautions.
      It does not represent any guarantee of the properties of the product. guidechem shall not be
      held liable for any damage resulting from handling or from contact with the above product.
      See reverse side of invoice or packing slip for additional terms and conditions of sale.

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15861 24-2

  • 1. Click http://www.guidechem.com/cas-158/15861-24-2.html for suppliers of this product 5-Cyanoindole (cas 15861-24-2) MSDS 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product identifiers Product name : Indole-5-carbonitrile Product Number : C92006 Brand : CAS-No. 15861-24-2 : 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Manufacture of substances 2. HAZARDS IDENTIFICATION 2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP] Skin irritation (Category 2) Eye irritation (Category 2) Specific target organ toxicity - single exposure (Category 3) Classification according to EU Directives 67/548/EEC or 1999/45/EC Irritating to eyes, respiratory system and skin. 2.2 Label elements Labelling according Regulation (EC) No 1272/2008 [CLP] Pictogram Signal word Warning Hazard statement(s) H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. Precautionary statement(s) P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. - C92006 Supplemental Hazard none Statements According to European Directive 67/548/EEC as amended. Hazard symbol(s) R-phrase(s) R36/37/38 Irritating to eyes, respiratory system and skin. S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 Wear suitable protective clothing. 2.3 Other hazards - none 3. COMPOSITION/INFORMATION ON INGREDIENTS 3.1 Substances Synonyms : 5-cyanoindole Formula : C9H6N2 Molecular Weight : 142,16 g/mol Component Concentration Indole-5-carbonitrile
  • 2. CAS-No. 15861-24-2 - EC-No. 239-986-4 4. FIRST AID MEASURES 4.1 Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 4.2 Most important symptoms and effects, both acute and delayed To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. 4.3 Indication of any immediate medical attention and special treatment needed no data available 5. FIREFIGHTING MEASURES 5.1 Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. - C92006 5.2 Special hazards arising from the substance or mixture Carbon oxides, nitrogen oxides (NOx) 5.3 Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. 5.4 Further information no data available 6. ACCIDENTAL RELEASE MEASURES 6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. 6.2 Environmental precautions Do not let product enter drains. 6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal. 6.4 Reference to other sections For disposal see section 13. 7. HANDLING AND STORAGE 7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection. 7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. 7.3 Specific end uses no data available 8. EXPOSURE CONTROLS/PERSONAL PROTECTION 8.1 Control parameters Components with workplace control parameters 8.2 Exposure controls
  • 3. Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Personal protective equipment Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. - C92006 Body Protection impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). 9. PHYSICAL AND CHEMICAL PROPERTIES 9.1 Information on basic physical and chemical properties a) Appearance Form: crystalline Colour: beige b) Odour no data available c) Odour Threshold no data available d) pH no data available e) Melting point/freezing Melting point/range: 106 - 108 °C - lit. point f) Initial boiling point and no data available boiling range g) Flash point no data available h) Evaporation rate no data available i) Flammability (solid, gas) no data available j) Upper/lower no data available flammability or explosive limits k) Vapour pressure no data available l) Vapour density no data available m) Relative density no data available n) Water solubility no data available o) Partition coefficient: n- no data available octanol/water p) Autoignition no data available temperature q) Decomposition no data available temperature r) Viscosity no data available s) Explosive properties no data available t) Oxidizing properties no data available 9.2 Other safety information no data available 10. STABILITY AND REACTIVITY 10.1 Reactivity no data available
  • 4. 10.2 Chemical stability no data available - C92006 10.3 Possibility of hazardous reactions no data available 10.4 Conditions to avoid no data available 10.5 Incompatible materials Strong oxidizing agents, Strong acids, Strong bases 10.6 Hazardous decomposition products Other decomposition products - no data available 11. TOXICOLOGICAL INFORMATION 11.1 Information on toxicological effects Acute toxicity LD50 Intravenous - mouse - 100 mg/kg Skin corrosion/irritation no data available Serious eye damage/eye irritation no data available Respiratory or skin sensitization no data available Germ cell mutagenicity no data available Carcinogenicity IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity no data available Specific target organ toxicity - single exposure Inhalation - May cause respiratory irritation. Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Potential health effects Inhalation May be harmful if inhaled. Causes respiratory tract irritation. Ingestion May be harmful if swallowed. Skin May be harmful if absorbed through skin. Causes skin irritation. Eyes Causes serious eye irritation. Signs and Symptoms of Exposure To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Additional Information RTECS: NL5993120 12. ECOLOGICAL INFORMATION 12.1 Toxicity no data available 12.2 Persistence and degradability no data available - C92006 12.3 Bioaccumulative potential no data available 12.4 Mobility in soil no data available 12.5 Results of PBT and vPvB assessment no data available 12.6 Other adverse effects no data available
  • 5. 13. DISPOSAL CONSIDERATIONS 13.1 Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION 14.1 UN number ADR/RID: - IMDG: - IATA: - 14.2 UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods 14.3 Transport hazard class(es) ADR/RID: - IMDG: - IATA: - 14.4 Packaging group ADR/RID: - IMDG: - IATA: - 14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no 14.6 Special precautions for user no data available 15. REGULATORY INFORMATION This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture no data available 15.2 Chemical Safety Assessment no data available 16. OTHER INFORMATION Further information The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information this document is based on the resent state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. guidechem shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale.