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MITOSIS

 How somatic (non-sex cells) divide and multiply.
Interphase
the cell gets itself ready for mitosis
the phase of the cell cycle in which the cell spends
the majority of its time and performs the majority
of its purposes including preparation for cell
division
In preparation for cell division, it increases its size
and makes a copy of its DNA
the cell obtains nutrients, grows, reads its DNA
Prophase
 the chromosomes become visible
 the centrosomes start to move away from each other
 the nuclear envelope starts to disperse
 the spindle begins to form
 the nucleoli disappear
 Chromatin present in the nucleus starts to condense and it can be
 seen through the light microscope as chromosomes. The nucleolus
 disappears. It begins to move to opposite poles of the cell and
 fibers extend from the centromeres.
Prometaphase
  tetrads become connected to the spindle fibers by kinetochores
  the nuclear envelope fragments
  Microtubules emerging from the centromeres at the poles (ends)
  of the spindle reach the chromosomes
  each sister chromatid has a protein structure called a
  kinetochore
  Some of the spindle microtubules attach to the kinetochores,
  throwing the chromosomes into agitated motion
  The nuclear membrane will be dissolved and it indicates the start
  of prometaphase stage. Kinetochores will be created because of
  the attachment of proteins to the centromeres. The
  chromosomes begin its movement when Microtubules attach at
  the kinetochores.
Metaphase
                plate



Spindle




          Centrosome at
          one spindle pole
Metaphase
 the alignment of chromosomes at the center of
 the cell
 the separation of sister chromatids to opposite
 mitotic spindle poles
 the centrosomes are now at opposite poles of the
 cell
 Spindle fibers align the chromosomes along the
 middle of the cell nucleus named metaphase plate
Daughter
chromosomes
Anaphase
  the chromatids separate and move toward the spindle poles
  Anaphase begins when the duplicated centromeres of each pair of
  sister chromatids separate
  At the end of anaphase, a complete set of chromosomes are
  assembled at each pole of the cell.
  The chromosome pairs separate at the kinetochores and move to
  opposite sides of the cell.
Telophase and Cytokinesis
     The polar fibers continue to lengthen
     Nuclei (plural form of nucleus) begin to form at opposite poles
     The nuclear envelopes of these nuclei are formed from remnant
     pieces of the parent cell's nuclear envelope
     Nucleoli (plural form of nucleolus) also reappear
     Chromatin fibers of chromosomes uncoil
     After these changes, telophase is complete and the genetic
     "contents" of one cell have been divided equally into two
     Cytokinesis, the division of the original cell's cytoplasm, begins
     prior to the end of mitosis and completes shortly after telophase
     In animal cells, cytokinesis involves involves the formation of a
     cleavage furrow, which pinches the cell in two

At the end of cytokinesis, there are two distinct daughter cells
MITOSIS

 The two daughter cells now become parent cells and each produce
two more daughter cell. This process continues to repeat

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Mitosis

  • 1. MITOSIS  How somatic (non-sex cells) divide and multiply.
  • 2.
  • 3. Interphase the cell gets itself ready for mitosis the phase of the cell cycle in which the cell spends the majority of its time and performs the majority of its purposes including preparation for cell division In preparation for cell division, it increases its size and makes a copy of its DNA the cell obtains nutrients, grows, reads its DNA
  • 4.
  • 5. Prophase the chromosomes become visible the centrosomes start to move away from each other the nuclear envelope starts to disperse the spindle begins to form the nucleoli disappear Chromatin present in the nucleus starts to condense and it can be seen through the light microscope as chromosomes. The nucleolus disappears. It begins to move to opposite poles of the cell and fibers extend from the centromeres.
  • 6.
  • 7. Prometaphase tetrads become connected to the spindle fibers by kinetochores the nuclear envelope fragments Microtubules emerging from the centromeres at the poles (ends) of the spindle reach the chromosomes each sister chromatid has a protein structure called a kinetochore Some of the spindle microtubules attach to the kinetochores, throwing the chromosomes into agitated motion The nuclear membrane will be dissolved and it indicates the start of prometaphase stage. Kinetochores will be created because of the attachment of proteins to the centromeres. The chromosomes begin its movement when Microtubules attach at the kinetochores.
  • 8. Metaphase plate Spindle Centrosome at one spindle pole
  • 9. Metaphase the alignment of chromosomes at the center of the cell the separation of sister chromatids to opposite mitotic spindle poles the centrosomes are now at opposite poles of the cell Spindle fibers align the chromosomes along the middle of the cell nucleus named metaphase plate
  • 11. Anaphase the chromatids separate and move toward the spindle poles Anaphase begins when the duplicated centromeres of each pair of sister chromatids separate At the end of anaphase, a complete set of chromosomes are assembled at each pole of the cell. The chromosome pairs separate at the kinetochores and move to opposite sides of the cell.
  • 12.
  • 13. Telophase and Cytokinesis The polar fibers continue to lengthen Nuclei (plural form of nucleus) begin to form at opposite poles The nuclear envelopes of these nuclei are formed from remnant pieces of the parent cell's nuclear envelope Nucleoli (plural form of nucleolus) also reappear Chromatin fibers of chromosomes uncoil After these changes, telophase is complete and the genetic "contents" of one cell have been divided equally into two Cytokinesis, the division of the original cell's cytoplasm, begins prior to the end of mitosis and completes shortly after telophase In animal cells, cytokinesis involves involves the formation of a cleavage furrow, which pinches the cell in two At the end of cytokinesis, there are two distinct daughter cells
  • 14. MITOSIS  The two daughter cells now become parent cells and each produce two more daughter cell. This process continues to repeat